Suggested Topics within your search.
Suggested Topics within your search.
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5401
Difficulties in diagnosing acute myocarditis by the example of a patient with decompensated chronic heart failure
Published 2024-11-01“…This clinical case demonstrates the high effectiveness of conservative therapy for CHF, its almost complete regression in a relatively short period. …”
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5402
Study of signal transduction factors involved in mycoparasitic response of Trichoderma atroviride
Published 2004-07-01“…For this purpose we have cloned the first genes (tmk1, tga1, tga3) from T. atroviride showing a high similarity to MAP kinase and G protein subunits (see abstract by Zeilinger et al.), which have been found to have an important role in pathogenicity by Magnaporthe grisea. To identify the function and involvement of these factors in mycoparasitism by T. atroviride, tmk1, tga1, tga3 disruptant strains were produced. …”
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5403
Managing Cracked Teeth with Root Extension: A Prospective Preliminary Study Using Biodentine™ Material
Published 2024-01-01“…Furthermore, these teeth were in occlusal function. Both radiographic and tomographic assessments revealed the absence of bone loss along the crack line. …”
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5404
From boundary data to bound states
Published 2020-01-01“…A simplified (more geometrical) map can be obtained for circular orbits, enabling us to extract the orbital frequency as a function of the (conserved) binding energy, Ω(E), directly from scattering information. …”
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5405
Classification of shoulder diseases in older adult patients: a narrative review
Published 2025-01-01“…Future research should focus on targeted interventions, standardized diagnostic criteria, and multidisciplinary collaboration to minimize disability, optimize function, and improve overall quality of life in this growing patient population. …”
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5406
Rapid and efficient isolation of high-quality small RNAs from recalcitrant plant species rich in polyphenols and polysaccharides.
Published 2014-01-01“…The acquisition of high-quality small RNAs is the first step in the study of its expression and function analysis, yet the extraction method of small RNAs in recalcitrant plant tissues with various secondary metabolites is not well established, especially for tropical and subtropical plant species rich in polysaccharides and polyphenols. …”
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5407
EV-D68 cleaves LARP1 and PABPC1 by 3Cpro to redirect host mRNA translation machinery toward its genomic RNA.
Published 2025-04-01“…We found that LARP1 interacts with the 5'UTR of EV-D68 RNA through its LAM domain, and this interaction is crucial for its antiviral function. LARP1 translation modulation is also influenced by the mTOR and CDK1 signaling pathways. …”
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5408
A Small Protein Associated with Fungal Energy Metabolism Affects the Virulence of Cryptococcus neoformans in Mammals.
Published 2016-09-01“…This gene, hereafter identified as HVA1 (hypervirulence-associated protein 1), encodes a protein that has homologs of unknown function in plant and animal fungi, consistent with a conserved mechanism. …”
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5409
Signal peptide-binding drug as a selective inhibitor of co-translational protein translocation.
Published 2014-12-01“…Despite their common function in Sec61 targeting and ER translocation, SPs have diverse but unique primary sequences. …”
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5410
Distinct Phenotypes Caused by Mutation of MSH2 in Trypanosome Insect and Mammalian Life Cycle Forms Are Associated with Parasite Adaptation to Oxidative Stress.
Published 2015-06-01“…Loss of the latter function results in life cycle dependent differences in phenotypic outcomes in T. brucei MSH2 mutants, most likely because of the greater burden of oxidative stress in the insect stage of the parasite.…”
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5411
Autosomal recessive transmission of a rare KRT74 variant causes hair and nail ectodermal dysplasia: allelism with dominant woolly hair/hypotrichosis.
Published 2014-01-01“…Furthermore, hair follicles and epidermis of an affected family member stained negative for Keratin-74 suggesting a loss of function mechanism mediated by the Phe274Ser substitution. …”
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5412
The significance of anti-PLA2R antibody in the diagnosis and treatment of primary membranous nephropathy
Published 2019-01-01“…Low anti-PLA2R baseline levels or decreased anti-PLA2R titers strongly predict spontaneous remission of PMN and are therefore more likely to be treated conservatively. In contrast, high anti-PLA2R baseline levels or elevated anti-PLA2R titers are associated with continuous presence of proteinuria and progressive decline in renal function, and thus tends to initiate immunosuppressive therapy. …”
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5413
An Angelman syndrome substitution in the HECT E3 ubiquitin ligase C-terminal Lobe of E6AP affects protein stability and activity.
Published 2020-01-01“…The HECT domain consists of an N-lobe, required for E2~ubiquitin recruitment, while the C-lobe contains the conserved catalytic cysteine required for ubiquitin transfer. …”
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5414
Identification of 17 HrpX-regulated proteins including two novel type III effectors, XOC_3956 and XOC_1550, in Xanthomonas oryzae pv. oryzicola.
Published 2014-01-01“…The function of some hypothetical proteins, possibly regulated by key hrp regulators, in the pathogenicity of phytopathogenic bacteria remains largely unknown. …”
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5415
Comparison of Different Prognostic Scoring Systems in Predicting the Severity and Outcome in Alcoholic Hepatitis in Indian Patients
Published 2025-05-01“…The various scores – Maddrey’s discriminant function (mDF), Glasgow AH score (GAHS), age, bilirubin, international normalized ratio (INR), creatinine score, and model of end-stage liver disease (MELD) including its modification MELD-sodium were calculated. …”
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5416
Resistance of <i>Wolbachia</i> to Trimethoprim: Insights into Genes Encoding Dihydrofolate Reductase, Thymidylate Synthase and Serine Hydroxymethyltransferase in the Rickettsiales
Published 2024-12-01“…The exclusive use of FAD-TS suggests that <i>Wolbachia</i> DHFR provides a supplementary rather than an essential function for de novo synthesis of dTMP, possibly reflecting the relative availability of, and competing demands for, FAD and NAD coenzymes in the diverse intracellular environments of its hosts. …”
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5417
Tibial Nerve injury in Medial Open Wedge-High Tibial Osteotomy – A Rare Complication with 14-Year Follow-Up
Published 2025-01-01“…At the end of 14 years, the motor function was fully recovered, but the patient still had residual paresthesia. …”
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5418
Tracking autophagy during proliferation and differentiation of Trypanosoma brucei
Published 2016-03-01“…The dynamins represent a superfamily of proteins that have been shown to function in a wide range of membrane fusion and fission events. …”
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5419
Augmenter of liver regeneration (alr) promotes liver outgrowth during zebrafish hepatogenesis.
Published 2012-01-01“…Augmenter of Liver Regeneration (ALR) is a sulfhydryl oxidase carrying out fundamental functions facilitating protein disulfide bond formation. …”
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5420
Identification and Expression Analysis of Polyphenol Oxidase Gene Family Members in Response to Wound Stress in Lettuce (<i>Lactuca sativa</i> L.)
Published 2025-03-01“…The results of this study provide a foundation for further investigation into the functional role of <i>LsPPOs</i> and support the development of lettuce varieties with enhanced resistance to browning.…”
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