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  1. 5401

    Difficulties in diagnosing acute myocarditis by the example of a patient with decompensated chronic heart failure by T.M. Shibaeva, A.E. Sheina, T.N. Belugina, E.S. Fokina, M.A. Saakyan

    Published 2024-11-01
    “…This clinical case demonstrates the high effectiveness of conservative therapy for CHF, its almost complete regression in a relatively short period. …”
    Article
  2. 5402

    Study of signal transduction factors involved in mycoparasitic response of Trichoderma atroviride by Scala V, Zeilinger S, Ambrosino P, Brunner K, Reithner B, Mach R L, Woo S L, Cristilli M, Scala F, Lorito M

    Published 2004-07-01
    “…For this purpose we have cloned the first genes (tmk1, tga1, tga3) from T. atroviride showing a high similarity to MAP kinase and G protein subunits (see abstract by Zeilinger et al.), which have been found to have an important role in pathogenicity by Magnaporthe grisea. To identify the function and involvement of these factors in mycoparasitism by T. atroviride, tmk1, tga1, tga3 disruptant strains were produced. …”
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    Article
  3. 5403

    Managing Cracked Teeth with Root Extension: A Prospective Preliminary Study Using Biodentine™ Material by Kênia Maria Soares de Toubes, Isabella Sousa Corrêa, Regina Célia Lopes Valadares, Stephanie Quadros Tonelli, Fábio Fernandes Borém Bruzinga, Frank Ferreira Silveira

    Published 2024-01-01
    “…Furthermore, these teeth were in occlusal function. Both radiographic and tomographic assessments revealed the absence of bone loss along the crack line. …”
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    Article
  4. 5404

    From boundary data to bound states by Gregor Kälin, Rafael A. Porto

    Published 2020-01-01
    “…A simplified (more geometrical) map can be obtained for circular orbits, enabling us to extract the orbital frequency as a function of the (conserved) binding energy, Ω(E), directly from scattering information. …”
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    Article
  5. 5405

    Classification of shoulder diseases in older adult patients: a narrative review by Hyo-Jin Lee, Jong-Ho Kim

    Published 2025-01-01
    “…Future research should focus on targeted interventions, standardized diagnostic criteria, and multidisciplinary collaboration to minimize disability, optimize function, and improve overall quality of life in this growing patient population. …”
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    Article
  6. 5406

    Rapid and efficient isolation of high-quality small RNAs from recalcitrant plant species rich in polyphenols and polysaccharides. by Jun Peng, Zihao Xia, Ling Chen, Minjing Shi, Jinji Pu, Jianrong Guo, Zaifeng Fan

    Published 2014-01-01
    “…The acquisition of high-quality small RNAs is the first step in the study of its expression and function analysis, yet the extraction method of small RNAs in recalcitrant plant tissues with various secondary metabolites is not well established, especially for tropical and subtropical plant species rich in polysaccharides and polyphenols. …”
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    Article
  7. 5407

    EV-D68 cleaves LARP1 and PABPC1 by 3Cpro to redirect host mRNA translation machinery toward its genomic RNA. by Ruyang Tan, Yuling Zhang, Mengqian Huang, Honghua Chen, Zixiang Liu, Zining Wang, Xiaoyan Li, Tao Wang, Zhiyun Wang

    Published 2025-04-01
    “…We found that LARP1 interacts with the 5'UTR of EV-D68 RNA through its LAM domain, and this interaction is crucial for its antiviral function. LARP1 translation modulation is also influenced by the mTOR and CDK1 signaling pathways. …”
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    Article
  8. 5408

    A Small Protein Associated with Fungal Energy Metabolism Affects the Virulence of Cryptococcus neoformans in Mammals. by Erin E McClelland, Udupi A Ramagopal, Johanna Rivera, James Cox, Antonio Nakouzi, Moses M Prabu, Steven C Almo, Arturo Casadevall

    Published 2016-09-01
    “…This gene, hereafter identified as HVA1 (hypervirulence-associated protein 1), encodes a protein that has homologs of unknown function in plant and animal fungi, consistent with a conserved mechanism. …”
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    Article
  9. 5409

    Signal peptide-binding drug as a selective inhibitor of co-translational protein translocation. by Kurt Vermeire, Thomas W Bell, Victor Van Puyenbroeck, Anne Giraut, Sam Noppen, Sandra Liekens, Dominique Schols, Enno Hartmann, Kai-Uwe Kalies, Mark Marsh

    Published 2014-12-01
    “…Despite their common function in Sec61 targeting and ER translocation, SPs have diverse but unique primary sequences. …”
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    Article
  10. 5410

    Distinct Phenotypes Caused by Mutation of MSH2 in Trypanosome Insect and Mammalian Life Cycle Forms Are Associated with Parasite Adaptation to Oxidative Stress. by Viviane Grazielle-Silva, Tehseen Fatima Zeb, Jason Bolderson, Priscila C Campos, Julia B Miranda, Ceres L Alves, Carlos R Machado, Richard McCulloch, Santuza M R Teixeira

    Published 2015-06-01
    “…Loss of the latter function results in life cycle dependent differences in phenotypic outcomes in T. brucei MSH2 mutants, most likely because of the greater burden of oxidative stress in the insect stage of the parasite.…”
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    Article
  11. 5411

    Autosomal recessive transmission of a rare KRT74 variant causes hair and nail ectodermal dysplasia: allelism with dominant woolly hair/hypotrichosis. by Doroteya Raykova, Joakim Klar, Aysha Azhar, Tahir Naeem Khan, Naveed Altaf Malik, Muhammad Iqbal, Muhammad Tariq, Shahid Mahmood Baig, Niklas Dahl

    Published 2014-01-01
    “…Furthermore, hair follicles and epidermis of an affected family member stained negative for Keratin-74 suggesting a loss of function mechanism mediated by the Phe274Ser substitution. …”
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    Article
  12. 5412

    The significance of anti-PLA2R antibody in the diagnosis and treatment of primary membranous nephropathy by XU Dong-mei, LIU Yi-peng

    Published 2019-01-01
    “…Low anti-PLA2R baseline levels or decreased anti-PLA2R titers strongly predict spontaneous remission of PMN and are therefore more likely to be treated conservatively. In contrast, high anti-PLA2R baseline levels or elevated anti-PLA2R titers are associated with continuous presence of proteinuria and progressive decline in renal function, and thus tends to initiate immunosuppressive therapy. …”
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    Article
  13. 5413

    An Angelman syndrome substitution in the HECT E3 ubiquitin ligase C-terminal Lobe of E6AP affects protein stability and activity. by Steven A Beasley, Chloe E Kellum, Rachel J Orlomoski, Feston Idrizi, Donald E Spratt

    Published 2020-01-01
    “…The HECT domain consists of an N-lobe, required for E2~ubiquitin recruitment, while the C-lobe contains the conserved catalytic cysteine required for ubiquitin transfer. …”
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    Article
  14. 5414

    Identification of 17 HrpX-regulated proteins including two novel type III effectors, XOC_3956 and XOC_1550, in Xanthomonas oryzae pv. oryzicola. by Xiao-bo Xue, Li-fang Zou, Wen-xiu Ma, Zhi-yang Liu, Gong-you Chen

    Published 2014-01-01
    “…The function of some hypothetical proteins, possibly regulated by key hrp regulators, in the pathogenicity of phytopathogenic bacteria remains largely unknown. …”
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    Article
  15. 5415

    Comparison of Different Prognostic Scoring Systems in Predicting the Severity and Outcome in Alcoholic Hepatitis in Indian Patients by Priyank Dhiman, Ritu Grewal, Pankaj Puri, Neel Kanth Issar, AS Prasad, Rahul Jain, Manasvi Kalra, Harshul Jain

    Published 2025-05-01
    “…The various scores – Maddrey’s discriminant function (mDF), Glasgow AH score (GAHS), age, bilirubin, international normalized ratio (INR), creatinine score, and model of end-stage liver disease (MELD) including its modification MELD-sodium were calculated. …”
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    Article
  16. 5416

    Resistance of <i>Wolbachia</i> to Trimethoprim: Insights into Genes Encoding Dihydrofolate Reductase, Thymidylate Synthase and Serine Hydroxymethyltransferase in the Rickettsiales by Ann M. Fallon

    Published 2024-12-01
    “…The exclusive use of FAD-TS suggests that <i>Wolbachia</i> DHFR provides a supplementary rather than an essential function for de novo synthesis of dTMP, possibly reflecting the relative availability of, and competing demands for, FAD and NAD coenzymes in the diverse intracellular environments of its hosts. …”
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    Article
  17. 5417

    Tibial Nerve injury in Medial Open Wedge-High Tibial Osteotomy – A Rare Complication with 14-Year Follow-Up by Woon-Hwa Jung, Aniket Wagh, Minseok Seo

    Published 2025-01-01
    “…At the end of 14 years, the motor function was fully recovered, but the patient still had residual paresthesia. …”
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    Article
  18. 5418

    Tracking autophagy during proliferation and differentiation of Trypanosoma brucei by Laila Moustaq, Iwona I. Smaczynska-de Rooij, Sarah E. Palmer, Christopher J. Marklew, Kathryn R. Ayscough

    Published 2016-03-01
    “…The dynamins represent a superfamily of proteins that have been shown to function in a wide range of membrane fusion and fission events. …”
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    Article
  19. 5419

    Augmenter of liver regeneration (alr) promotes liver outgrowth during zebrafish hepatogenesis. by Yan Li, Muhammad Farooq, Donglai Sheng, Chanchal Chandramouli, Tian Lan, Nilesh K Mahajan, R Manjunatha Kini, Yunhan Hong, Thomas Lisowsky, Ruowen Ge

    Published 2012-01-01
    “…Augmenter of Liver Regeneration (ALR) is a sulfhydryl oxidase carrying out fundamental functions facilitating protein disulfide bond formation. …”
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    Article
  20. 5420

    Identification and Expression Analysis of Polyphenol Oxidase Gene Family Members in Response to Wound Stress in Lettuce (<i>Lactuca sativa</i> L.) by Mei Guo, Yueming Tang, Yiwen Yang, Jinghong Luo, Jia Gao

    Published 2025-03-01
    “…The results of this study provide a foundation for further investigation into the functional role of <i>LsPPOs</i> and support the development of lettuce varieties with enhanced resistance to browning.…”
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    Article