Genome-wide identification of the ATP-dependent zinc metalloprotease (FtsH) in Triticeae species reveals that TaFtsH-1 regulates cadmium tolerance in Triticum aestivum. by Yuxi Huang, Lifan Cao, Tanxing Chen, Xiaoqiang Chang, Yumei Fang, Liuliu Wu

“…Barley stripe mosaic virus-induced gene silencing (BSMV-VIGS) technology confirmed the function of TaFtsH-1, indicating that silencing TaFtsH-1 enhances common wheat's resistance to cadmium (Cd) toxicity. …”
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The C-terminal domain of the Arabinosyltransferase Mycobacterium tuberculosis EmbC is a lectin-like carbohydrate binding module. by Luke J Alderwick, Georgina S Lloyd, Hemza Ghadbane, John W May, Apoorva Bhatt, Lothar Eggeling, Klaus Fütterer, Gurdyal S Besra

“…The same substitutions differentially abrogated binding of di- and penta-arabinofuranoside acceptor analogues to EmbC(CT), linking the loss of activity to compromised acceptor substrate binding, indicating the presence of two separate carbohydrate binding sites, and demonstrating that subdomain II indeed functions as a carbohydrate-binding module. This work provides the first step towards unravelling the structure and function of a GT-C-type glycosyltransferase that is essential in M. tuberculosis.…”
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Genome wide identification of AGC kinase genes and their expression in response to heat and cold stresses in barley by Zohreh HAJIBARAT, Abbas SAIDI

“…AGC kinases are highly conserved regulators in a variety of cellular processes such as differentiation, proliferation, and growth.  …”
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The Result of the Treatment of Optic Nerve Edema after COVID-19 by E. E. Ioyleva, A. Yu. Safonenko, A. O. Otyrba, E. S. Loban

“…A 59-year-old man with reduced visual functions in the post-surgical period was examined. …”
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Basonuclin-2 requirements for zebrafish adult pigment pattern development and female fertility. by Michael R Lang, Larissa B Patterson, Tiffany N Gordon, Stephen L Johnson, David M Parichy

“…We show that the bonaparte mutant phenotype arises from mutations in basonuclin-2 (bnc2), encoding a highly conserved, nuclear-localized zinc finger protein of unknown function. …”
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Transvaginal natural orifice specimen extraction surgery in simple nephrectomy by Jeena R. Kudunthail, Kartik Sharma, Deepak Prakash Bhirud, Mahendra Singh, Gautam Ram Choudhary, Shiv Charan Navriya, Arjun Singh Sandhu

“…The complication rate was 6.67%, with one case of vaginal bleeding which was managed conservatively. Postoperative pelvic floor and sexual functions were preserved without significant adverse effects. …”
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The crystal structure of the orphan nuclear receptor NR2E3/PNR ligand binding domain reveals a dimeric auto-repressed conformation. by M H Eileen Tan, X Edward Zhou, Fen-Fen Soon, Xiaodan Li, Jun Li, Eu-Leong Yong, Karsten Melcher, H Eric Xu

“…In this conformation, the putative ligand binding pocket is filled with bulky hydrophobic residues and the activation-function-2 (AF2) helix occupies the canonical cofactor binding site. …”
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A novel sterol regulatory element-binding protein gene (sreA) identified in penicillium digitatum is required for prochloraz resistance, full virulence and erg11 (cyp51) regulation... by Jing Liu, Yongze Yuan, Zhi Wu, Na Li, Yuanlei Chen, Tingting Qin, Hui Geng, Li Xiong, Deli Liu

“…The putative SreA protein contains a conserved domain of unknown function (DUF2014) at its carboxyl terminus and a helix-loop-helix (HLH) leucine zipper DNA binding domain at its amino terminus, domains that are functionally associated with SREBP transcription factors. …”
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Exploring the influence of symbiosis between arbuscular mycorrhizal fungi and beans on potassium uptake and the activity of AKT and HKT genes by Zahra Alizadeh, Parviz Heidari, Hamid Reza Asghari

“…Abstract In plants, potassium (K+) serves multiple functions, despite being scarce due to strong soil adsorption. …”
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Caspase 3 and caspase 7 promote cytoprotective autophagy and the DNA damage response during non-lethal stress conditions in human breast cancer cells. by Gayathri Samarasekera, Nancy E Go, Courtney Choutka, Jing Xu, Yuka Takemon, Jennifer Chan, Michelle Chan, Shivani Perera, Samuel Aparicio, Gregg B Morin, Marco A Marra, Suganthi Chittaranjan, Sharon M Gorski

“…We found a functionally conserved role for effector caspase 3 (CASP3) and caspase 7 (CASP7) in promoting starvation or proteasome inhibition-induced cytoprotective autophagy in human breast cancer cells. …”
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The gene regulatory cascade linking proneural specification with differentiation in Drosophila sensory neurons. by Sebastián Cachero, T Ian Simpson, Petra I Zur Lage, Lina Ma, Fay G Newton, Eimear E Holohan, J Douglas Armstrong, Andrew P Jarman

“…High-resolution temporal profiling of gene expression reveals the events downstream of atonal proneural gene function during the development of Drosophila chordotonal (mechanosensory) neurons. …”
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NS5A domain I antagonises PKR to facilitate the assembly of infectious hepatitis C virus particles. by Shucheng Chen, Mark Harris

“…DI and DII have been shown to function in genome replication, whereas DIII has a role in virus assembly. …”
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Current Measurement and Fault Detection Based on the Non-Invasive Smart Internet of Things Technique by Abhrodeep Chanda, Abhishek Gudipalli

“…Nonlinearity varies from 0.2% to 0.3% as a function of increasing current; nonetheless, offsets are imperceptible under typical operating conditions. …”
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New Insights into Meteorological and Hydrological Drought Modeling: A Comparative Analysis of Parametric and Non-Parametric Distributions by Ahmad Abu Arra, Eyüp Şişman

“…Accurate drought monitoring depends on selecting an appropriate cumulative distribution function (CDF) to model the original data, resulting in the standardized drought indices. …”
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In-depth analysis of endogenous retrovirus expression in glioblastoma by Daniel A. Murimi-Worstell, Irene B. Murimi-Worstell, Farrah M. Roy, Aidan Burn, Michael Freeman, Ralph B. Puchalski, John M. Coffin

“…Abstract Background Human endogenous retroviruses (HERVs) are remnants of ancient viral infections and comprise 6–8% of the human genome. Their biological functions in cancer remain poorly understood, especially in glioblastoma, the most common and deadly primary brain cancer in adults. …”
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The Efficacy of Treatment of Hemangiomas in Infants with Nonselective β-Blockers (Propranolol) by Kuzyk A.

“…Hemangiomas – are tumorlike vessel changes that occur in children starting from an early age and can appear as minor cosmetic defects that sometimes spontaneously decrease, or can cause serious functional disorders or even be a threat to life. As of today the choice of treatment strategy remains controversial. …”
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Expression divergence of BAG gene family in maize under heat stress by Babar Farid, Muhammad Abu Bakar Saddique, Muhammad Hammad Nadeem Tahir, Rao Muhammad Ikram, Zulfiqar Ali, Waseem Akbar

“…Once the plant is under heat stress, the BAG genes act as co-chaperones and modulate the molecular functions of HSP70/HSC70 saving the plant from the damage of high temperature stress. …”
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Characterizing genetic pathways unique to autism spectrum disorder at multiple levels of biological analysis by Lukas S. Schaffer, Sophie Breunig, Jeremy M. Lawrence, Isabelle F. Foote, Andrew D. Grotzinger

“…Abstract Background Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by atypical patterns of social functioning and repetitive/restricted behaviors. ASD commonly co-occurs with ADHD and, despite their clinical distinctiveness, the two share considerable genetic overlap. …”
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Identification and expression analysis of TALE superfamily genes explore their key roles in response to abiotic stress in Brassica napus by Meili Xie, Xiaojuan Zhang, Kexin Liu, Zhixian Qiao, Xiaohui Cheng

“…BnTALE members in the same subclass or branch of the phylogenetic tree generally showed similar gene structures and conserved domain compositions, which may indicate that they have similar biological functions. …”
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Mechanism of Rad51 filament formation by Rad52 and Rad55-Rad57 in homologous recombination by Jaigeeth Deveryshetty, Ayush Mistry, Sushil Pangeni, Mohamed Ghoneim, Monica Tokmina-Lukaszewska, Steven K. Gore, Jie Liu, Vikas Kaushik, Simrithaa Karunakaran, Angela Taddei, Wolf-Dietrich Heyer, Taekjip Ha, Brian Bothner, Edwin Antony

“…Despite structural differences, Rad52 and BRCA2 share conserved functional features. We propose a unified “Sort, Stack & Extend” (SSE) mechanism by which mediator proteins and paralogs coordinate Rad51 filament assembly during HR.…”
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