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The light chains of microtubule-associated proteins MAP1A and MAP1B interact with α1-syntrophin in the central and peripheral nervous system.
Published 2012-01-01“…Microtubule-associated proteins of the MAP1 family (MAP1A, MAP1B, and MAP1S) share, among other features, a highly conserved COOH-terminal domain approximately 125 amino acids in length. …”
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5203
Maternal Oxytocin Is Linked to Close Mother-Infant Proximity in Grey Seals (Halichoerus grypus).
Published 2015-01-01“…Oxytocin's structure and function is widely conserved across mammalian mothers, including humans. …”
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A High Affinity hRpn2-Derived Peptide That Displaces Human Rpn13 from Proteasome in 293T Cells.
Published 2015-01-01“…We propose that this hRpn2-derived peptide could be used to develop peptide-based strategies that specifically target hRpn13 function in the proteasome.…”
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Microtubule actin crosslinking factor 1 regulates the Balbiani body and animal-vegetal polarity of the zebrafish oocyte.
Published 2010-08-01“…In mgn mutants, the oocyte nucleus is mislocalized; and the Balbiani body, localized mRNAs, and organelles are absent from the periphery of the oocyte, consistent with a function for macf1 in nuclear anchoring and cortical localization. …”
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The Hippo Pathway Targets Rae1 to Regulate Mitosis and Organ Size and to Feed Back to Regulate Upstream Components Merlin, Hippo, and Warts.
Published 2016-08-01“…Here we identify Rae1 as a highly-conserved target of the Hippo Pathway integrating proliferation and organ size. …”
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Model-Based Offline Reinforcement Learning for AUV Path-Following Under Unknown Ocean Currents with Limited Data
Published 2025-03-01“…To address this, we propose a conservative offline model-based Q-learning (CMQL) algorithm. …”
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PROBLEMS OF DIAGNOSIS AND TREATMENT OF PATIENTS WITH BACKGROUND PROCESSES AND TUMOR PATHOLOGY OF THE VULVA
Published 2018-12-01“…It is possible to reduce the frequency of postoperative complications and improve the functional and cosmetic results of the treatment only with the use of reconstructive plastic surgery. …”
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Paraoesophageal ectopic parathyroid adenoma: an unusual case
Published 2025-07-01“…SPECT CT combines the advantages of anatomical and functional imaging and offers improved sensitivity for localising ectopic parathyroid adenomas3 (Fig.1). …”
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Mixed lipopeptide-based mucosal vaccine elicits a long-term bone marrow memory response that is potentially cross-reactive against a broad-spectrum of coronaviruses in mice
Published 2025-07-01“…To address that need, we have designed a mixed lipopeptide-based pan-coronavirus (LPMix) vaccine based on T and B cell epitopes derived from highly conserved and functional regions of the SARS-CoV-2 spike (S), nucleocapsid (N), and membrane (M) proteins.MethodsMale C57BL/6 mice (n=5 per group) were immunized intranasally twice, 14 days apart, with the LPMix vaccine candidates, which consisted of seven lipopeptides (LP1–LP7), with or without HKCC (heat-killed Caulobacter crescentus), a novel mucosal adjuvant. …”
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Response Patterns of Three Types of Biocrust to Reduced Rainfall
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Genome-Wide Identification, Characterization, and Comparison of <i>C3HC4</i> Family Genes in Salt Tolerance Between Barley and Rice
Published 2025-08-01“…This study systematically investigated the evolution and functional specialization of the C3HC4-type RING zinc finger gene family, known to mediate abiotic stress responses through E3 ubiquitin ligase activity, in these contrasting cereal species. …”
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Viral RNA polymerase as a SUMOylation decoy inhibits RNA quality control to promote potyvirus infection
Published 2025-01-01“…TuMV NIb is comprised of two functional SUMO interacting motif (SIM): SIM2 and SIM3. …”
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Structure of endothelin ETB receptor–Gi complex in a conformation stabilized by unique NPxxL motif
Published 2024-10-01“…In this study, we present the cryo-EM structure of the ETBR–Gi complex, complemented by MD simulations and functional studies. These investigations reveal an unusual movement of TM7 to the intracellular side during ETBR activation and the essential roles of the diverse NPxxL motif in stabilizing the active conformation of ETBR and organizing the assembly of the binding pocket for the α5 helix of Gi protein. …”
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Plant AT-rich protein and zinc-binding protein (PLATZ) family in Dendrobium huoshanense: identification, evolution and expression analysis
Published 2024-12-01“…The Ka/Ks analysis revealed a pattern of purifying selection after duplication occurrences, suggesting little alterations in functional divergence. The collinearity and microsynteny results revealed that the three DhPLATZ genes shared the same conserved domains as the paralogs from D. huoshanense and D. chrysotoxum. …”
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Bioinformatics analysis of the tomato (Solanum lycopersicum) methylesterase gene family
Published 2025-05-01“…Cis-acting element analyses suggested that the SlMES family may have important regulatory functions in tomato growth, development, and stress responses. …”
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A plant Bcl-2-associated athanogene is proteolytically activated to confer fungal resistance
Published 2016-04-01“…The Bcl-2-associated athanogene (BAG) family is a multifunctional group of proteins involved in numerous cellular functions ranging from apoptosis to tumorigenesis. …”
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New classes of mind bomb-interacting proteins identified from yeast two-hybrid screens.
Published 2014-01-01“…Finally, functions of confirmed Mib/Mib2-interacting proteins are collated, summarized and hypothesized, which depicts a regulating network beyond Notch signaling.…”
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