Differences in composition and potential function of the bacterial communities of cave- and surface-dwelling Mexican salamanders by Julio César García-Sánchez, Sean M. Rovito

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Functional Characterization of the Osteoarthritis Susceptibility Mapping to CHST11-A Bioinformatics and Molecular Study. by Louise N Reynard, Madhushika Ratnayake, Mauro Santibanez-Koref, John Loughlin

“…These are all located within intron 2 of CHST11, in a region that has predicted enhancer activity and which shows a high degree of conservation in primates. Luciferase reporter assays revealed that of the seven SNPs, rs835487 and rs835488, which have a pairwise r2 of 0.962, are the top functional candidates; the haplotype composed of the OA-risk conferring G allele of rs835487 and the corresponding T allele of rs835488 (the G-T haplotype) demonstrated significantly different enhancer activity relative to the haplotype composed of the non-risk A allele of rs835487 and the corresponding C allele of rs835488 (the A-C haplotype) (p < 0.001). …”
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Hybrid Artificial Neural Network Activation Function to Reduce Water Wastage in Agricultural Irrigation by Baraa H. Jawad, Ola A. Alwesabi, Nibras Abdullah, Ahmed Abed Mohammed

“…The achievement of this is done by utilizing a hybrid activation function known as TanElu, which combines the Tanh and ELU functions. …”
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Identification of degradation risk areas and delineation of key ecological function areas in Qinling region by Xiaojuan Xu, Dayi Lin, Yue Yang, Jing Liu, Changxin Zou, Naifeng Lin, Fusheng Jiao, Qian Wu, Jie Qiu, Kun Zhang

“…This study examines the improvement and decline in the Qinling region from 2000 to 2023 in terms of ecosystem patterns, quality, and functions. Moreover, key ecological function and degradation risk zones were identified, and future development paths were proposed for the Qinling region. …”
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FLORA: a novel method to predict protein function from structure in diverse superfamilies. by Oliver C Redfern, Benoît H Dessailly, Timothy J Dallman, Ian Sillitoe, Christine A Orengo

“…Overall, we show that FLORA is able to effectively detect functionally similar protein domain structures by purely using patterns of structural conservation of all residues.…”
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Evolutionary Dynamics and Functional Bifurcation of the C2H2 Gene Family in Basidiomycota by Chao Duan, Jie Yang

“…This study performed a phylogenomic analysis of the C2H2 gene family across 30 Basidiomycota species, identifying 1032 genes distributed across six evolutionary clades (Groups I–VI). Functional diversification and lineage-specific expansions were observed: Group II (37.1%) formed a conserved core, while wood decayers (e.g., <i>Schizophyllum commune</i>) and edible fungi (e.g., <i>Pleurotus ostreatus</i>) exhibited clade-specific expansions in Groups III and V, respectively. …”
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Baru Proteins: Extraction Methods and Techno-Functional Properties for Sustainable Nutrition and Food Innovation by Nayara Matiko Reis Miyashita, Eliara Acipreste Hudson, Jaqueline de Paula Rezende, Márcia Cristina Teixeira Ribeiro Vidigal, Ana Clarissa dos Santos Pires

“…This review discusses the nutritional composition, protein extraction methods and techno-functional properties of baru almonds, highlighting both advantages and limitations for food application. …”
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Multi-omics analysis reveals the evolution, function, and regulatory mechanisms of SPF pheromones in Anurans by Puyang Zheng, Yunyun Lv, Yuzhou Gong, Gang Wang, Bin Wang, Xiuqin Lin, Xun Liao, Jianghong Ran, JiaTang Li, Feng Xie

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Stabilization of nonlinear safety-critical systems by relaxed converse Lyapunov-barrier approach and its applications in robotic systems by Haoqi Li, Jiangping Hu, Xiaoming Hu, Bijoy K. Ghosh

“…Existing studies generally unified these two objectives by constructing Lyapunov-type barrier functions. However, insufficient analysis of key set relationships within the system may render the proposed safety and stability conditions conservative, and these studies also did not provide how to use such conditions to design safety-stability control strategies. …”
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Identification of the ACA/ECA gene family and preliminary verification of their functional in calcium transport in lettuce by Yuxuan Qian, Zhanhui Wu, Ning Liu, Baoju Wang, Jing Tong

“…In this study, we utilized bioinformatics methods to identify and analyze members of the ACA/ECA gene family in lettuce. The functions of certain ACA/ECA genes in lettuce were preliminary validated using TRV-VIGS. …”
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Identification of the functional domains of canine tetherin in antiviral activity against canine influenza virus by Jiajun Ou, Jiajun Ou, Jiajun Ou, Yixin Dai, Yujie Jiang, Lingzhi Dai, Liang Xu, Gang Lu, Gaoming Lou, Shoujun Li

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Connecting Natural and Planted Forests: New Ecological Functions in an Agricultural Landscape in Northern Spain by Javier Brazuelo Núñez, Carlos A. Rivas, Guillermo Palacios-Rodríguez, Rafael M. Navarro-Cerrillo

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Hurricanes lead to declines in taxonomic, phylogenetic, and functional richness and shifts in moth community composition by Aura M. Alonso‐Rodríguez, Pablo E. Gutiérrez‐Fonseca, Ingi Agnarsson, Catherine M. Hulshof, Scott E. Miller, Taylor H. Ricketts

“…Abstract Disturbances play a central role in shaping biodiversity, influencing both community structure and ecosystem function. The responses of biodiversity to disturbance are inherently multidimensional, often leading to shifts in taxonomic composition, functional traits, and evolutionary dynamics within biological communities. …”
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Spatial Analysis of the Functional Andean Worldview of the Archaeological Site of Ankasmarka, Cusco—Peru 2024 by Doris Esenarro, Jimena Ccalla, Guisela Yabar, Cecilia Uribe, Mario Reyes, Mirko De los Santos, Geoffrey Salas, Javier Condori

“…The objective of this research is to conduct a spatial analysis of the functional Andean worldview of the Ankasmarka Archaeological Site, located in Calca, Peru. …”
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The Spatiotemporal Variation and Ecological Evaluation of Macroinvertebrate Functional Feeding Groups in the Upper Yellow River by Peilun Li, Shuhan Xiong, Jiacheng Liu, Tai Wang, Yanbin Liu, Kai Liu, Yongjie Wang, Jilong Wang

“…Against the backdrop of hydropower development in the upper Yellow River, comprehending the spatiotemporal variation and ecological evaluation of macroinvertebrate functional feeding groups (FFGs) is paramount for the conservation and restoration of aquatic biological resources in watersheds. …”
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Development of soil quality assessment framework: A comprehensive review of indicators, functions, and approaches by Ya’nan Fan, Chao Zhang, Wenyou Hu, Khalid Saifullah Khan, Yongcun Zhao, Biao Huang

“…In this study, bibliometric analysis was applied to systematically present the development of soil quality assessment research, elucidating the complex interrelationships among soil functions, assessment indicators, and approaches. The results indicated that while the volume of publications on soil quality assessment has steadily increased, with a notable surge between 2018 and 2022, the primary research topics remain focused on soil fertility and productivity, soil environment and safety, soil health and conservation, as well as soil assessment and management. …”
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Deciphering the comprehensive microbiome of glacier-fed Ganges and functional aspects: implications for one health by Rachel Samson, Shubham Kumar, Syed Dastager, Krishna Khairnar, Mahesh Dharne

“…In this study, we developed an efficient DNA extraction and amplification method using low-input DNA to sequence the microbiome from sediments of the glacier-fed Ganges River in pre-monsoon and post-monsoon over 2 years. Taxonomic and functional diversity of bacterial and viral (phage) communities were analyzed, together with the seasonal variations in their composition. …”
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Clinical phenotype and functional influence of GRIN2A variants in epilepsy‐aphasia syndrome by Lu Zhang, Yiran Duan, Rui Ma, Jiaqi Han, Na Pan, Lehong Gao, Yuping Wang

“…Abstract Objective N‐methyl‐D‐aspartate receptors are glutamate‐gated ion channels that play a crucial role in brain function. Numerous inherited or de novo variants in the GRIN2A gene, encoding the GluN2A subunit of the receptor, have been identified in patients with epilepsy. …”
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A functional selection model explains evolutionary robustness despite plasticity in regulatory networks by Naomi Habib, Ilan Wapinski, Hanah Margalit, Aviv Regev, Nir Friedman

“…Despite this turnover, the biological processes associated with a motif are generally conserved. We explain these trends using a model with a strong selection to conserve the overall function of a transcription factor, and a much weaker selection over the specific genes it targets. …”
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Linking Peroxiredoxin and Vacuolar-ATPase Functions in Calorie Restriction-Mediated Life Span Extension by Mikael Molin, Ayse Banu Demir

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