The Ironbridge Gorge Heritage Site and its local and regional functions by Cudny Waldemar

“…The article is devoted to the issue of heritage and its functions. Based on the existing literature, the author presents the definition of heritage, the classification of heritage resources, and its most important impacts. …”
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Evolutionary and Functional Relationships of the dha Regulon by Genomic Context Analysis. by Marinalva Martins-Pinheiro, Wanessa C Lima, Huma Asif, Cláudio A Oller, Carlos F M Menck

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Herbivore community function shapes resilience and bistability of coral reefs. by Shayna A Sura, James O Lloyd-Smith, Peggy Fong

“…Empirical studies demonstrate functionally-diverse herbivorous fish communities support coral reef resilience to anthropogenic impacts. …”
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Molecular evolution and functional characterization of Drosophila insulin-like peptides. by Sebastian Grönke, David-Francis Clarke, Susan Broughton, T Daniel Andrews, Linda Partridge

“…Furthermore, loss of brain DILPs blocked the responses of lifespan and fecundity to dietary restriction (DR) and the DR response of these mutants suggests that IIS extends lifespan through mechanisms that both overlap with those of DR and through additional mechanisms that are independent of those at work in DR. Evolutionary conservation has thus been accompanied by synergy, redundancy, and functional differentiation between DILPs, and these features may themselves be of evolutionary advantage.…”
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Rare species support vulnerable functions in high-diversity ecosystems. by David Mouillot, David R Bellwood, Christopher Baraloto, Jerome Chave, Rene Galzin, Mireille Harmelin-Vivien, Michel Kulbicki, Sebastien Lavergne, Sandra Lavorel, Nicolas Mouquet, C E Timothy Paine, Julien Renaud, Wilfried Thuiller

“…Our results emphasize the importance of rare species conservation, even in highly diverse ecosystems, which are thought to exhibit high functional redundancy. …”
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An Analysis of Spatial Variation in Human Impact on Forest Ecological Functions by Qingjun Wu, Liyong Fu, Ram P. Sharma, Yaquan Dou, Xiaodi Zhao

“…As the cornerstone of terrestrial ecosystems, forests have faced mounting challenges due to escalating human activities, jeopardizing their vital ecological functions and even their existence. It has become an important issue to explore how to promote harmonious coexistence of man and nature, or even to improve the forest ecological function (FEF) through human activities. …”
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Functional exploration of the IFT-A complex in intraflagellar transport and ciliogenesis. by Bing Zhu, Xin Zhu, Limei Wang, Yinwen Liang, Qianqian Feng, Junmin Pan

“…The IFT43 conserved domain is necessary and sufficient for the function of IFT43. …”
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ATP plays a structural role in Hsp90 function by Michael Reidy, Daniel C. Masison

“…The role of ATP in Hsp90 function is unclear since cell viability requires ATP binding, but not hydrolysis. …”
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Structure guided functional analysis of the S. cerevisiae Mre11 complex by Marcel Hohl, You Yu, Vitaly Kuryavyi, Dinshaw J. Patel, John Petrini

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The aspartate-less receiver (ALR) domains: distribution, structure and function. by Andrew F Maule, David P Wright, Joshua J Weiner, Lanlan Han, Francis C Peterson, Brian F Volkman, Nicholas R Silvaggi, Andrew T Ulijasz

“…To propagate a signaling response the typical system employs a sensory histidine kinase that phosphorylates a Receiver (REC) domain on a conserved aspartate (Asp) residue. Although it is known that some REC domains are missing this Asp residue, it remains unclear as to how many of these divergent REC domains exist, what their functional roles are and how they are regulated in the absence of the conserved Asp. …”
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On the Complete Lattice Structure of Ordered Functional Weighted Averaging Operators by Roberto G. Aragón, Jesús Medina, Samuel Molina-Ruiz, Ronald R. Yager

“…Ordered functional weighted averaging (OFWA) operators are a generalization of the well-known ordered weighted averaging (OWA) operators in which functions, instead of single values, are considered as weights. …”
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Application of integrating VC cross-connecting function with OTN system by Heping LIN, Cheng WANG, Jinliang ZHANG, Jixian CAO, Zhiying GAO, Shuai KANG

“…Due to the advantage of rigidity pipeline,SDH is irreplaceable in carrying high priority service circuit.However,it will withdraw because of equipment ageing.A solution of OTN system with VC cross-connecting function was proposed for the situation which SDH network faced,which could minimize space requirements,conserve energy,save the resource of optical fiber and reduce the operational risk while keeping the advantage of OTN high bandwidth transmission.Pilot testing proves that the system works well and accords with correlative criterion.…”
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Integrins in disguise – mechanosensors in Saccharomyces cerevisiae as functional integrin analogues by Tarek Elhasi, Anders Blomberg

“…In addition, many important components in integrin-dependent signalling in humans are conserved in yeast; for example, Sla1 and Sla2 are homologous to different parts of human talin, and we propose that they together might be functionally similar to talin. …”
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Krüppel-like factor 4 control of immune cell function by Tapatee Das, Elaine Wang, Yitian Xu, Harrison Yang, Xudong Liao, Mukesh K. Jain, Mukesh K. Jain

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Molecular mechanisms and biological functions of active DNA demethylation in plants by Ruixian Zhu, Yan Xue, Weiqiang Qian

“…In this review, we will discuss the molecular mechanisms, regulation, and biological functions of active DNA demethylation in plants.…”
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Functions and regulation of the MRX complex at DNA double-strand breaks by Elisa Gobbini, Corinne Cassani, Matteo Villa, Diego Bonetti, Maria Pia Longhese

“…Furthermore, it is responsible for DSB signaling by activating the checkpoint kinase Tel1 that, in turn, supports MRX function in a positive feedback loop. The present review focuses mainly on recent works in the budding yeast Saccharomyces cerevisiae to highlight structure and regulation of MRX as well as its interplays with Tel1.…”
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Exploiting functional regions in the viral RNA genome as druggable entities by Dehua Luo, Yingge Zheng, Zhiyuan Huang, Zi Wen, Lijun Guo, Yingxiang Deng, Qingling Li, Yuqing Bai, Shozeb Haider, Dengguo Wei

“…An essential prerequisite for their design depends on identifying conserved and functional viral RNA structures in cells. …”
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Decoding PDI diversity: Insights into structure, domains, and functionality in sorghum by Carla F. López-Gómez, Marc T. Morris, Karen Massel, Millicent Smith, Peter Crisp, Gerhard Schenk, Ian D. Godwin

“…Proteins play indispensable roles in cellular function, acting as both structural components and catalysts for essential biological processes. …”
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YmoA functions as a molecular stress sensor in Yersinia by Tifaine Héchard, Lu Lu, Tomas Edgren, Chi Celestine, Helen Wang

“…The YmoA/Hha protein family are conserved transcription regulators in Enterobacteriaceae, playing a critical role in these responses. …”
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Interdependence of Pasha and Drosha for localization and function of the Microprocessor in C. elegans by Thiago L. Knittel, Brooke E. Montgomery, Kailee J. Reed, Madeleine C. Chong, Ida J. Isolehto, Erin R. Cafferty, Margaret J. Smith, Reese A. Sprister, Colin N. Magelky, Hataichanok Scherman, René F. Ketting, Taiowa A. Montgomery

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