Enhanced Acute Muscle Activation in ALS Patients Following Liposomal Curcumin, Resveratrol, and Dutasteride Administration by Julio Martín-Ruiz, Rosa Maset-Roig, Jordi Caplliure-Llopis, Carlos Villarón-Casales, Jorge Alarcón-Jiménez, Nieves de Bernardo, Belén Proaño, Rubén Menargues-Ramírez, Pablo Selvi-Sabater, José Enrique de la Rubia-Ortí

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Integrating large language models in biostatistical workflows for clinical and translational research by Steven C. Grambow, Manisha Desai, Kevin P. Weinfurt, Christopher J. Lindsell, Michael J. Pencina, Lacey Rende, Gina-Maria Pomann

“…Methods: A cross-sectional survey was conducted across three biostatistics units at two academic medical centers. …”
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Simulation of the Extraction Efficiency of Coalbed Methane under Water Injection: A Gas-Liquid-Solid Coupling Model by Hai Pu, Liqiang Zhang, Xu Dong, Tao Jing, Xu Junce

“…The experimental results show that the elastic modulus and compressive strength decrease as an exponential function with increasing water pressure. Based on the experimental results, a gas-liquid-solid coupling model including effective stress change and gas desorption is established and used to predict a field gas extraction application. …”
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Compound Action Potential of Isolated Spinal Cord: A Biophysical Analysis to Address Activity of Individual Fibers Following Contusion Injury by I. Rad, K. Khodayari, S. Kouhzaei, H. Mobasheri

“…The current approach can be applied in the identification and evaluation of spinal cord function for experimental and clinical purposes.…”
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Mapping and assessing the multifunctional demand for agricultural land based on the “P-E-F” framework: A case study of Hangzhou City, China by Qian Yu, Shan He, Chenxia Hu, Shixue You, Lin Lin, Yue Su, Congmou Zhu, Chenhe Zhou

“…Finally, we comprehensively analyzed the demand variations among land use types and agricultural functions to explore more precise information. The key findings are that 1) despite high MAL demand was generally concentrated near the downtown, some remote rural areas were also characterized by significant demand for cultural function; 2) compared to that of ecological and cultural functions, the production demand was less scale-dependent with a more aggregated distribution pattern; 3) agricultural land with compounding demand was clustered in the plains adjacent to cities, and hotspots of MAL demand in remote mountains were less frequently observed; 4) demand level for paddy field was outstanding among other agricultural land use types. …”
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Exploring the life experiences of school‐aged children afflicted by tethered spinal cord syndrome: An interpretative qualitative study by Nan Lin, Mingxian Ren, Yujun Xiang, Jiahuan Li, Dan Wang, Hongzhen Xu

“…Nonetheless, healthcare professionals tend to prioritise the physical functionality of the afflicted individuals throughout the treatment and rehabilitation process, often neglecting the emotional experiences and requirements of these children as they transition into posthospitalization phases. …”
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Pediatric resident use, perceptions, and desires for improvement of a clinical secure messaging application by Andrew W Halterman, Anneli R Cochrane, Andrew D Miller, Joy L Lee, William E Bennett, Jr, Emily L Mueller

“…Methods: A survey was conducted of pediatric residents regarding their experience with Diagnotes®. …”
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Distribution of macrozoobenthic taxa - potential indicators of vulnerable marine ecosystems in the western part of Bering Sea. 1. Anadyr Bay area by Victor A. Nadtochy, Nickolay V. Kolpakov, Ilya A. Korneichuk

“…This by-effect of fishing could affect negatively on functioning of bottom biocenoses, reproduction of exploited species, and decrease generally productivity of vulnerable marine ecosystems (VME). …”
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Retinol and Hydroxyasiaticoside Synergistically Relieve Histamine-Induced Atopic Dermatitis Activity by Repressing TRPV1, L1R1, and CD130 Targets by Qin Liu, Peng Shu, Qingle Song, Zhenhai Huang, Jiyu Weng, Lanyue Zhang, Yuan Wang, Qingqing Liu

“…<b>Background:</b> Retinol, an important bioactive substance with multiple physiological functions such as promoting collagen synthesis, inhibiting matrix metalloproteinase activity, alleviating oxidative stress, regulating gene expression, and promoting epidermal cell proliferation, has a significant effect on skin damage recovery. …”
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ENHANCEMENT OF SENSOR PANEL TACTILE TOUCH INTERFACE by Oleksandr Karpin, Zinovii Liubun, Vasyl Mandziy, Oleh Tereshchuk, Nestor Hotsiy

“…Therefore, it can be employed cost-effectively to enhance the functionality of touch panels. The algorithm's ability to detect gestures using a single button makes it an attractive solution for applications where space is limited, such as in wearable devices or mobile phones. …”
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Exploring potential methylation markers for ovarian cancer from cervical scraping samples by Ju-Yin Lien, Lu Ann Hii, Po-Hsuan Su, Lin-Yu Chen, Kuo-Chang Wen, Hung-Cheng Lai, Yu-Chao Wang

“…Furthermore, an over-representation analysis was conducted to explore the functions associated with genes mapped from differentially methylated positions (DMPs) in comparisons between normal and tumor samples, as well as between benign and malignant samples. …”
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A usability evaluation framework for a mobile application in supporting home-based rehabilitation for stroke patients: A qualitative study by Shih-Ying Chien

“…Conclusions Satisfaction and performance surveys and qualitative data analysis revealed that most participants described the interface design of the app as intuitive and easy to use. Although some functions presented challenges, there was still a high level of satisfaction among both groups. …”
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Dissecting biological heterogeneity in major depressive disorder based on neuroimaging subtypes with multi-omics data by Lili Tang, Rui Tang, Junjie Zheng, Pengfei Zhao, Rongxin Zhu, Yanqing Tang, Xizhe Zhang, Xiaohong Gong, Fei Wang

“…The amplitude of low-frequency fluctuations (ALFF), a functional neuroimaging feature, was extracted for each participant and used to identify MDD subtypes through machine learning clustering. …”
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The Kinematic Signature of the Warp and Waves in the Milky Way Disk by Weixiang Sun, Han Shen, Biwei Jiang, Xiaowei Liu

“…Using over 170,000 red clump (RC) stars selected from LAMOST and APOGEE, we conduct a detailed analysis of the stellar V _Z as a function of L _Z (or R _g ) across different ϕ bins for various disk populations. …”
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Revealing the Immune Response of <i>Sitona callosus</i> Gyllenhal to Entomopathogenic Fungi <i>Beauveria bassiana</i> Infection Through Integrative Analyses of Transcriptomics and... by Nan Li, Xin Gu, Ming Xin, Xinpu Wang

“…The transcriptomic analysis unveiled that <i>B. bassiana</i> infection boosted immune responses in tubercula, affecting carbohydrate metabolism, cytochrome P450 activity, lysosome function, apoptosis regulation, phagosome formation, glutathione metabolism, amino acid metabolism, and pathogen response pathways. …”
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DC-SIGN Receptor Level in Rheumatoid Arthritis Patients in Baghdad; Serological study by Hayam A. Mohammed, Zahra’a A. Ahmed, Aymen A. Othman Alrawi

“…DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. …”
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Use and diagnostic value of liver enzyme tests in the emergency department and subsequent heart failure diagnosis: a retrospective cohort study by Mark Pletcher, Elena Vasti, Jeffrey A Tabas, Ari Hoffman

“…Objectives To determine (1) if liver function tests (LFTs) are ordered in the emergency department (ED) in patients with suspected acute decompensated heart failure (ADHF) and (2) if the pattern of LFT abnormalities are meaningfully associated with a discharge diagnosis of ADHF among patients for whom these tests were ordered.Setting We conducted a single-centre retrospective cohort study of patients with suspected ADHF who were seen in an academic tertiary ED using electronic medical records.Participants All ED patients admitted with suspected ADHF from January 2017 to May 2018, defined as any patient who had a brain natriuretic peptide (BNP) ordered.Primary outcome The primary outcome was ADHF diagnosis at discharge.Results In 5323 ED patients with suspected ADHF, 60% (n=3184) had LFTs ordered; 34.6% were abnormal. …”
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Experimental Study on Tunnel Failure Mechanism and the Effect of Combined Anti-Dislocation Measures Under Fault Dislocation by Jiaxuan Du, Songhong Yan, Weiyu Sun, Mingxing Cao, Yuxiang Li

“…Taking the tunnels crossing active faults in China’s Sichuan–Tibet Railway as the research background, experimental studies were conducted using a custom-developed split model box. …”
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Pathophysiological mechanisms in severe preeclampsia: role of upregulated proteins in blood pressure, extracellular matrix and immunity by Caroline Cristina Pinto-Souza, Julyane Natsumi Saito Kaihara, Bruno César Rossini, Ricardo de Carvalho Cavalli, Lucilene Delazari dos Santos, Valéria Cristina Sandrim

“…Protein identification and annotation were performed using UniProt and PatternLab for Proteomics. Multivariate statistical analyses, including PLS-DA and sPLS-DA, as well as VIP score evaluation and Volcano plot visualization, were conducted with MetaboAnalyst to assess group separation and identify key discriminative features. …”
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CGREF1 modulates osteosarcoma proliferation by regulating the cell cycle through the Wnt/β-catenin signaling pathway by Zicheng Wei, Kezhou Xia, Wenda Liu, Xinghan Huang, Zhun Wei, Weichun Guo

“…Cell counting kit-8 (CCK-8) assay, colony formation assay, flow cytometry, wound healing assay, and Transwell assay were conducted for in vitro functional experiments. In vivo experiments involved subcutaneous tumor formation in nude mice. …”
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