Calculating willingness-to-pay with discrete cost and random coefficients in discrete choice experiments by Clarence Ong, Alex R. Cook, Ker-Kan Tan, Yi Wang

“…Adding a quadratic cost term only partially solved the problem, as the quadratic functional form may not capture the sharp change in preference for cost at low-cost levels. …”
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The Potential Biological Roles and Clinical Significance of Anaphase-Promoting Complex Subunit 1 in Colorectal Cancer by Yi Chen MD, Yu-Xing Tang MD, Da-Tong Zeng MD, Jia-Ying Wen MD, Yan-Ting Zhan MD, Dong-Ming Li MD, Rong-Quan He MD, Zhi-Guang Huang MD, Yu-Zhen Chen MD, Qiu-Yu Wei MD, Gang Chen PhD, Yu-Lu Tang MD, Hui Li MD

“…Materials and methods This study integrated 2329 mRNA expression data, single-cell RNA sequencing (scRNA-seq), and internal immunohistochemistry of 416 tissue samples to comprehensively evaluate the abnormal expression pattern of ANAPC1 in CRC. It also incorporated evidence from immune infiltration analysis, functional enrichment analysis, and weighted gene co-expression network analysis to explore the biological behaviour of ANAPC1 in CRC. …”
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Differential regulation of calcium-NFAT signaling pathway by Akt isoforms: unraveling effector dynamics and exhaustion of cytotoxic T lymphocytes in tumor microenvironment by Hung-Chih Yang, Li-Rung Huang, Ulrike Protzer, Wen-Ling Chen, Yong-Lin Chang, Su-Fang Lin, Masanori Isogawa

“…We subsequently conducted western blotting, flow cytometry, and RNA sequencing analysis to assess their Akt expression, expression of immune checkpoints, antitumor/antivirus functionalities, and transcriptome. …”
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Reorganization of brain connectivity in post-COVID condition: a 18F-FDG PET study by Antoine Verger, Matthieu Doyen, Sebastien Heyer, François Goehringer, Alexandra Bruyere, Elsa Kaphan, Meriem Chine, Amélie Menard, Tatiana Horowitz, Eric Guedj

“…Abstract Background A hypometabolic brain pattern has been reported in patients with post-COVID condition (PCC). …”
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Determining Groundwater Recharge from Stream Flow with Seasonal Recession Method by Ichwana -, Zulkifli Nasution, Sumono -

“…The results showed that the trend pattern of the stream hydrograph could be explained using the exponential function where the dots lowest discharge that is the end of the recession (y) than any period of time on stream hydrograph semi logarithmic (x). …”
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Distinct steps of neural induction revealed by Asterix, Obelix and TrkC, genes induced by different signals from the organizer. by Sonia Pinho, Pamela R Simonsson, Katherine E Trevers, Matthew J Stower, William T Sherlock, Mohsin Khan, Andrea Streit, Guojun Sheng, Claudio D Stern

“…To define signals and responses during the first 5 hours of node signals, a differential screen was conducted. Here we describe three early response genes: two of them, Asterix and Obelix, encode previously undescribed proteins of unknown function but Obelix appears to be a nuclear RNA-binding protein. …”
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Influence of seasonal variation on in vitro fertilization success. by Michal Kirshenbaum, Alon Ben-David, Eran Zilberberg, Tal Elkan-Miller, Jigal Haas, Raoul Orvieto

“…<h4>Methods & materials</h4>A total of 5,765 IVF cycles conducted in Sheba medical center between 2013 and 2016 were retrospectively analyzed. …”
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Iris Microcirculation After Selective Laser Trabeculoplasty: A Pilot Optical Coherence Tomography Angiography Study by Dmitrii S. Maltsev, Alexey N. Kulikov, Alina A. Kazak

“…OCTA examination of the iris was performed before SLT and one day and seven days after SLT using RTVue-XR with a 3 mm scan pattern and follow-up function. Iris vascularity was calculated with ImageJ software (version 1.53k) as vessel density on binarized images. …”
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Morphometric and Genetic Characterization of Dominant Fish Species in Progo River, Yogyakarta, Indonesia by null Mulyasari, null Subaryono, Bagus Sediadi Bandol Utomo, Imam Taufik, Irin Iriana Kusmini, null Yosmaniar

“…Based on the results of discriminant function analysis, all wader fish from the Progo River used in this study were classified into three species with the highest differentiation character D4 (distance between the starting point of upper tail fin and the starting point of lower tail fin). …”
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Identification of Attention Deficit Hyperactivity Disorder Using Parent-teacher Administered ADHD Rating Scale-IV among Pre-school Children of Belagavi City by Deepa C. Metgud, Vinanti Sanjay Makasare

“…Background: Attention deficit hyperactivity disorder (ADHD) is a developmental disorder with a persistent pattern of distractibility, hyperactivity, restlessness, and other disturbances of executive function. …”
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Optimal Charging Current Protocol with Multi-Stage Constant Current Using Dandelion Optimizer for Time-Domain Modeled Lithium-Ion Batteries by Seongik Han

“…A composite objective function that incorporates both charging time and charging temperature was constructed to facilitate the use of DO in obtaining the OCP. …”
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A Low-Power Electrothermal Flexible Actuator with Independent Heating Control for Programmable Shape Deformation by Shen Dai, Zhiyao Ling, Han Gong, Kunwei Zheng

“…Compared to traditional actuators, the proposed design offers significant improvements in bending angle, response speed, and voltage requirements. By optimizing the conductive silver paste pattern and voltage input strategy, this work develops a low-voltage, highly controllable, multi-mode programmable actuator with potential for applications in flexible robotics and space-deformable antennas.…”
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Stenotrophomonas maltophilia virulence and specific variations in trace elements during acute lung infection: implications in cystic fibrosis. by Arianna Pompilio, Domenico Ciavardelli, Valentina Crocetta, Ada Consalvo, Roberta Zappacosta, Carmine Di Ilio, Giovanni Di Bonaventura

“…Overall, our data clearly indicate that S. maltophilia modulates pulmonary metal balance in a concerted and virulence-dependent manner highlighting the potential role of the element dyshomeostasis during the progression of S. maltophilia infection, probably exacerbating the harmful effects of the loss of CF transmembrane conductance regulator function. Further investigations are required to understand the biological significance of these alterations and to confirm they are specifically caused by S. maltophilia.…”
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Placental whole transcriptome expression profile in patients with early-onset, late-onset preeclampsia and gestational diabetes mellitus by Zhuo Chen, Li Yang, Li Geng, Xinwen Zhang, Mingyu Du, Yonghu Sun, Lin Zhao, Bing Bai, Xiaohong Li

“…The results revealed dysregulation of key pathways in early-onset-PE (OE-PE), including Wnt signaling, PI3K-Akt signaling, MAPK signaling, FoxO signaling, and TNF signaling, along with downregulation of genes related to Ca2 + conduction and hormone pathways. In late-onset-PE (LO-PE) and GDM, abnormalities were observed in immune pathways including chemokine signaling pathway and IL-17 signaling pathway, with differing immune cell infiltration patterns. …”
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Alcohol vs. Cocaine: Impulsivity and Alexithymia in Substance Use Disorder by Alessio Mosca, Giovanna Bubbico, Clara Cavallotto, Stefania Chiappini, Rita Allegretti, Andrea Miuli, Carlotta Marrangone, Nicola Ciraselli, Mauro Pettorruso, Giovanni Martinotti

“…Among the most prevalent substances of abuse, alcohol and cocaine are known to exert distinct effects on neuropsychological functioning. This study aimed to compare individuals with Alcohol Use Disorder (AUD) and Cocaine Use Disorder (CUD) in terms of impulsivity and alexithymia, and to examine the clinical implications of poly-substance use involving both alcohol and cocaine. …”
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Association of TLR2 Arg753Gln gene polymorphism with its expression level in nonagenarians with frailty by S. O. Lukyanova, O. V. Artemieva, E. D. Nasaeva, L. V. Gankovskaya

“…The increased frequency of occurrence of the Arg/Gln genotype of the Arg753Gln polymorphism of the TLR2 gene in nonagenarians with frailty may be due to increased gene expression of this receptor. It is necessary to conduct further functional and molecular genetic studies.…”
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De Novo Synthesis of Anticholinergic Hyoscyamine and Scopolamine in <i>Nicotiana benthamiana</i> Based on Elucidating Tropane Alkaloid Biosynthetic Pathway of <i>Anisodus luridus</... by Mengling Wen, Junlan Zeng, Fei Qiu, Fangyuan Zhang, Zhihua Liao

“…Its high yield of hyoscyamine makes <i>A. luridus</i> a valuable plant source for commercially producing TAs. In this study, we conduct homologous gene research across transcriptome data of different tissues together with functionally tested sequences in <i>Atropa belladonna</i> as a reference and identify 13 candidate genes for TAs biosynthesis in <i>A. luridus</i>. …”
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Design and Experimentation of a Height-Adjustable Management Platform for Pineapple Fields by Sili Zhou, Fengguang He, Ganran Deng, Ye Dai, Xilin Wang, Bin Yan, Pinlan Chen, Zehua Liu, Bin Li, Dexuan Pan

“…To address the challenges of inadequate adaptability, insufficient power, high ground clearance, and limited functionality in existing pineapple field machinery, this study proposes a height-adjustable pineapple field management platform based on previously established cultivation patterns and agronomic requirements. …”
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The impact of Alzheimer's disease on cortical complexity and its underlying biological mechanisms by Leian Chen, Xiao Zhou, Yanan Qiao, Yu Wang, Zhi Zhou, Shuhong Jia, Yu Sun, Dantao Peng

“…In addition, transcription–neuroimaging association analyses, as well as Mendelian randomization of AD and cortical thickness data, were conducted to investigate the genetic mechanisms and biological functions of AD. …”
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Brain-hemispheric differences in the premotor area for motor planning: An approach based on corticomuscular connectivity during motor decision-making by Leonardo A. Cano, Ana L. Albarracín, Fernando D. Farfán, Eduardo Fernández

“…These results emphasize the distinct functional roles of the left and right hemispheres in motor planning and underscore the importance of CMC in understanding the neural mechanisms underlying motor control. …”
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