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The Relationship between Core Muscles Dysfunction and Chronic Ankle Instability: A Review
Published 2019-09-01“…Methods In this review study, search was conducted in three online databases of PubMed, Scopus, and Google scholar based on Patient, Intervention, Comparison, Outcome (PICO) strategy, and using keywords related to the role and function of core muscles, their electromyography, kinematic patterns of proximal segments, and postural stability in individuals with chronic ankle instability. …”
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622
Elucidating the role of KLRD1 in coronary atherosclerosis: harnessing bioinformatics and machine learning to advance understanding
Published 2025-05-01“…Functional assays highlighted KLRD1's role in mononuclear cell differentiation, regulation of cell–cell adhesion, regulation of T cell activation. …”
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623
Design and Characterisation of an EIT Current Supply Module
Published 2024-12-01“…The imput fitering functioned similarly to the simulation of the design. …”
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624
Fine-mapping and initial characterization of QT interval loci in African Americans.
Published 2012-01-01“…Linkage disequilibrium (LD) patterns in African Americans assisted in narrowing the region likely to contain the functional variants for several loci. …”
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625
Distinct potency of compounds targeting the T1R3 subunit in modulating the response of human sweet and umami taste receptors
Published 2025-07-01“…The difference in the heterodimeric partners to T1R3 may account for their distinct modulation patterns of receptor function.…”
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626
Biogeography of freshwater plants in four major lakes in Kenya
Published 2024-04-01“…To bridge this knowledge gap, we conducted extensive field surveys and applied statistical methods to understand the patterns of distribution, density, and diversity of freshwater plants and their relationship with abiotic components in four freshwater lakes in Kenya. …”
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627
Marangoni Convection of Self-Rewetting Fluid Layers with a Deformable Interface in a Square Enclosure and Driven by Imposed Nonuniform Heat Energy Fluxes
Published 2025-07-01“…To achieve this, we have enhanced a central-moment-based lattice Boltzmann method (LBM) utilizing three distribution functions for tracking interfaces, computing two-fluid motions with temperature-dependent surface tension and energy transport, respectively. …”
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628
Common and distinct neural underpinnings of the association between childhood maltreatment and depression and aggressive behavior
Published 2025-01-01“…First, we employed Network-Based Statistics (NBS) on resting-state functional magnetic resonance imaging (fMRI) data to identify functional connectivity (FC) patterns associated with depression and aggression. …”
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629
Economic growth and urban metamorphosis: A quarter century of transformations within the metropolitan area of Bucharest
Published 2018-02-01“…This paper concentrates explicitly on examining the structural and functional transformations occurring within the metropolitan area of Bucharest, resulting from sustained economic growth during the past quarter century, by conducting a time analysis, spanning the entire period since the fall of the communist regime in late 1989. …”
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630
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631
The role of microbiomes in animal invasions: a scoping review
Published 2025-05-01“…We conducted a scoping review of studies focusing on microbiomes and animal invasions to explore the extent and nature of research efforts on this topic and to identify general patterns that may help elucidate the relationship between host microbial communities and invasiveness. …”
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632
TRANSFORMASI FUNGSI SIRING PADA RUMAH TRADISIONAL BUGIS DI BULUKUMBA
Published 2021-06-01“…Keywords: Form; Function; Activity Pattern; Siring; Traditional House. …”
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633
Effects of physical multimorbidity on cognitive decline trajectories among adults aged 50 years and older with different wealth status: a 17-year population-based cohort study
Published 2024-01-01“…Mixed multilevel models with quadratic terms of time and status/patterns indicated significant non-linear trajectories of multimorbidity on cognitive function. …”
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634
The Efficacy and Brain Network Mechanism of Acupuncture for Knee Osteoarthritis: A Study Protocol for Randomized Controlled Neuroimaging Trial
Published 2025-01-01“…Forty healthy subjects will be recruited for observation, with a single MRI scan conducted only at baseline (− 1– 0 week). The primary efficacy indicator will be the change in NRS score after four weeks of treatment, with secondary outcomes including WOMAC, STAI, and safety assessments. fMRI observations will employ independent component analysis, brain network construction, and functional connectivity, complemented by Pearson correlation analysis to explore the relationship between brain responses and clinical improvements.Conclusion: This study will initially uncover how acupuncture intervention for chronic KOA pain centrally regulates and exerts therapeutic effects through the modulation of abnormal brain network functional connectivity patterns, with a demonstrated long-term effect.Ethics and Dissemination: This study has been approved by the ethics committee of Shandong University of Traditional Chinese Medicine Affiliated Hospital ((2024) Lunshen No. (028) - KY).Clinical Trial Registration: This study has been approved by registered in the Chinese Clinical Trial Registry (ChiCTR2400083695).Keywords: acupuncture, knee osteoarthritis, neuroimaging, RCT, protocol…”
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635
Circadian clock features define novel subtypes among breast cancer cells and shape drug sensitivity
Published 2025-02-01“…However, applying these strategies in cancer remains limited due to a lack of understanding of the clock’s function across cancer types and incomplete insights into how the circadian clock affects drug responses. …”
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636
Pan-cancer analysis and validation show GTF2E2's diagnostic, prognostic, and immunological roles in regulating ferroptosis in endometrial cancer.
Published 2025-01-01“…There is a lack of more detailed research on the biological function of GTF2E2 in pan-cancer.<h4>Methods</h4>We conducted a comprehensive pan-cancer analysis using data from The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) project. …”
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637
Parity influences postpartum adaptations in the maternal gut microbiota
Published 2025-05-01“…We identified parity-specific signatures, with first-time mothers showing enrichment in Dysosmobacter welbionis, Candidatus Saccharibacteria, and Anaerotruncus species. Functional analysis revealed distinct metabolic reprogramming patterns, including increased amino acid biosynthesis and modified fermentation pathways supporting postpartum recovery. …”
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638
Systematic Construction and Validation of a Novel Ferroptosis-Related Gene Model for Predicting Prognosis in Cervical Cancer
Published 2022-01-01“…Ferroptosis-related differential genes in cervical cancer were detected using the “limma” R function and WGCNA. The least absolute shrinkage and selection operator (LASSO) algorithm and Cox regression analysis were conducted to develop a novel prognostic signature. …”
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639
60 Investigating sociodemographic influence on trauma exposure and neural alterations in young adults
Published 2025-04-01“…It also seeks to explore functional connectivity and neural network patterns associated with trauma by analyzing resting state magnetic resonance imaging (MRI) data. …”
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640
Exosomal circ_0006896 promotes AML progression via interaction with HDAC1 and restriction of antitumor immunity
Published 2025-01-01“…The role of circ_0006896 in the progression of AML was assessed by in vitro and in vivo functional experiments. Flow cytometry, RT-qPCR and adoptive T cell-transfer immunotherapy were conducted to assess the function of exosomal circ_0006896 in CD8+ T cell dysfunction. …”
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