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1721
NSUN6 expression correlates with prognosis and immune infiltration in human cancers based on pan-cancer analysis
Published 2025-07-01“…To further understand NSUN6’s role, a detailed Gene Set Enrichment Analysis (GSEA) was conducted, revealing its enrichment patterns in various carcinoma subtypes and hinting at its involvement in tumor growth. …”
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1722
An FPGA-Based SiNW-FET Biosensing System for Real-Time Viral Detection: Hardware Amplification and 1D CNN for Adaptive Noise Reduction
Published 2025-01-01“…Notably, the findings presented in this work are based exclusively on comprehensive simulations using COMSOL and MATLAB, as no physical prototypes or biomarker detection experiments were conducted. The SiNW-FET biosensor, functionalized with antibodies specific to viral antigens, detects impedance shifts caused by antibody–antigen interactions, providing a highly sensitive platform for viral detection. …”
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1723
Improved smart city security using a deep maxout network-based intrusion detection system with walrus optimization
Published 2025-03-01“…The DMN is configured with an architecture that includes multiple layers with maxout activation functions. These layers are capable of capturing complex patterns in the data, making the DMN particularly effective for identifying anomalies in IoT network traffic. …”
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1724
<i>DBI</i> as a Novel Immunotherapeutic Candidate in Colorectal Cancer: Dissecting Genetic Risk and the Immune Landscape via GWAS, eQTL, and pQTL
Published 2025-05-01“…Further validation was performed using The Cancer Genome Atlas (TCGA) to assess gene expression patterns and prognostic significance. Additionally, immune infiltration analysis was conducted to characterize the tumor immune microenvironment. …”
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1725
Study on the Wind Pressure Distribution in Complicated Spatial Structure Based on k-ε Turbulence Models
Published 2025-05-01“…Furthermore, scalable wall functions and non-structured grids with appropriate refinement on both turbulent regions and structural surfaces are also adopted in the RANS method. …”
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1726
Identification and characterization of soybean phytochrome-interacting factors and their potential roles in abiotic stress
Published 2024-12-01“…Nevertheless, research on PIFs in soybean is relatively scarce. In this study, we conducted a comprehensive analysis of the gene structure, chromosomal location, conserved motifs, phylogenetic relationships, and expression patterns of the Glycine max PIF (GmPIF) genes. …”
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1727
Real-world safety of carboplatin in non-small cell lung cancer: a retrospective signal detection and subgroup analysis based on the FAERS database
Published 2025-06-01“…Patients aged ≥65 years showed increased multisystem involvement, particularly affecting hematologic and renal functions.DiscussionThese findings underscore the necessity of tailored monitoring strategies for carboplatin, taking into account patient sex and age, especially when used in conjunction with immunotherapy. …”
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1728
Genome-wide characterization and expression analysis of the JRL gene family in response to hormones and abiotic stress in tomato (Solanum lycopersicum L.)
Published 2025-07-01“…Our results lay the foundation for further studies on the biological functions of tomato JRL genes.…”
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1729
Potential influence of geomagnetic activity on blood pressure statistical fluctuations at mid-magnetic latitudes
Published 2025-04-01“…Abstract Background Solar activity and the consequent geomagnetic activity (GMA) profoundly influence human biological rhythms and cardiovascular system functions. Although the response of blood pressure (BP) to GMA has attracted considerable attention, it is unclear whether the GMA can have an influence alone and how it occurs. …”
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1730
Genome-wide identification of fasciclin-like arabinogalactan proteins (FLAs) in melon and the role of CmFLA8 in glucose accumulation in fruit
Published 2025-01-01“…In this study, CmFLAs play a negative role in sugar accumulation and fruit ripening in melon, providing new insights into FLA gene functions.…”
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1731
RNF213 governs divergent tumor-immune dynamics across human cancers: a prognostic biomarker for immunotherapy stratification
Published 2025-07-01“…Conclusion This study highlights RNF213’s dual functionality in tumor progression and immune modulation, underscoring its potential as both a prognostic biomarker and a therapeutic target. …”
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1732
Occupational Exposure to Engine Exhausts and Prostate Cancer Risk
Published 2025-07-01“…As most associations were not linear, we fitted functions for changes in percentile distributions based on natural cubic splines. …”
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1733
Disentangled similarity graph attention heterogeneous biological memory network for predicting disease-associated miRNAs
Published 2024-12-01“…Additionally, various ablation studies were conducted to validate the contributions of different modules within the framework, and’s encoding statuses and memory units of DiGAMN were visualized to explore the utility and functionality of its modules. …”
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1734
Nitrogen addition promotes the coupling of deep soil carbon and nitrogen under different vegetation restoration types in the Chinese Loess Plateau
Published 2025-03-01“…Afforestation should be conducted in a way of natural restoration. This study provides novel insights into the regulatory mechanisms of C and N biogeochemistry and the afforestation patterns of vegetation restoration in arid and semi-arid regions.…”
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1735
Patients with chronic hepatitis B under nucleos(t)ide analog therapy with Omicron BA.5 infection: A retrospective study in South China
Published 2025-03-01“…Clinical features, encompassing COVID-19-related symptoms, levels of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies, vaccination status, liver functions, and virological markers of hepatitis B virus (HBV) infection were measured. …”
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1736
Information Propagation in Hypergraph-Based Social Networks
Published 2024-11-01“…Social networks, functioning as core platforms for modern information dissemination, manifest distinctive user clustering behaviors and state transition mechanisms, thereby presenting new challenges to traditional information propagation models. …”
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1737
Evaluating the effects of climate-induced heatwaves on the thermal dynamics and water quality of a deep reservoir in Portugal
Published 2025-08-01“…The study also underscores the importance of hydrodynamic forcing functions, such as inflow temperature and atmospheric variability, in shaping thermal stratification and circulation patterns. …”
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1738
Sex differences in schizophrenia: symptomatology, treatment efficacy and adverse effects
Published 2025-06-01“…Men typically experience illness onset approximately 3–5 years earlier than women, with more severe negative symptoms, worse social functioning, and higher rates of comorbid substance use disorders. …”
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1739
Microbial community composition and co-occurrence network analysis of the rhizosphere soil of the main constructive tree species in Helan Mountain of Northwest China
Published 2024-10-01“…By analyzing the response of rhizosphere microbial communities of major tree species in Helan Mountain to nutrient dynamics and pH changes, we can deepen our understanding of the role of microorganisms in regulating ecosystem functions and provide theoretical basis for soil improvement and ecological restoration strategies.…”
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1740
The Influence of Eco-Anxiety on Sustainable Consumption Choices: A Brief Narrative Review
Published 2025-07-01“…<b>Results:</b> Findings suggest that eco-anxiety functions as a cognitive–affective motivator for sustainable consumer choices; however, the strength and direction of this influence appear contingent on moderating emotional and psychological variables and cross-cultural and demographic moderators. …”
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