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1441
Spatiotemporal Agglomeration, Response Mode, and Interpretation Model of Daily Activities of Residents in Large Public Housing Areas in Nanjing Based on Household Labor Division
Published 2025-06-01“…In this context, we characterized and compared the spatiotemporal response patterns of the daily activities of residents in this type of residential area. …”
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1442
Identification of aging-related biomarkers for intervertebral disc degeneration in whole blood samples based on bioinformatics and machine learning
Published 2025-04-01“…To further validate these findings, we collected human blood specimens and conducted in vitro experiments. ELISA assays confirmed that CBS and FASLG are crucial biomarkers of IVDD, with distinct expression patterns in patients with moderate versus severe degeneration.DiscussionThese results highlight the diagnostic potential of AIDEGs and provide a new perspective for early intervention and treatment strategies in IVDD.…”
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1443
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1444
Detailed Time-resolved Spectral and Temporal Investigations of SGR J1550–5418 Bursts Detected with Fermi Gamma-Ray Burst Monitor
Published 2025-01-01“…We have conducted a time-resolved spectral analysis of magnetar bursts originating from SGR J1550−5418. …”
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1445
Pathogenetic and clinical signifcance of EpCАM expression features in tumors and circulating tumor cells
Published 2024-11-01“…Purpose of the study: to summarize the available data on the structure and function of EpCAM and its domains, their roles in promoting proliferation and epithelial-mesenchymal transition (EMT), contributing to cell stemness, and facilitating interactions with cell adhesion and invasion molecules.Material and Methods. …”
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1446
Genome-wide identification and characterization of the CCT gene family in Chinese cabbage (Brassica rapa) response to abiotic stress
Published 2025-07-01“…Overall, this study offers a theoretical foundation for further investigating the significant role of the CCT gene family in the functional genome of Chinese cabbage.…”
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1447
Pelagic fish camouflage in shallow waters from the humboldt current system through intracellular structures and reflectance mechanisms
Published 2025-08-01“…Furthermore, this study presents the first fish classifiers based on the analysis of spatial frequency features, achieving up to 92.14% accuracy using a K-Nearest Neighbors classifier, highlighting the functional and taxonomic relevance of guanine microstructure organization. …”
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1448
Genome-wide identification, expression analysis, and response to abiotic stress of the phosphate transporter gene family in cucumber (Cucumis sativus L.)
Published 2025-05-01“…Conclusion This study conducted a systematic analysis of the CsPHT gene family, which provides a theoretical foundation and candidate genes for subsequent functional characterization and the genetic improvement of abiotic stress tolerance in cucumber.…”
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1449
Integrated genomic and transcriptomic analysis of polydactyly in chickens
Published 2025-05-01“…These findings offer clear targets for functional validation and may guide selective breeding for limb traits in poultry.…”
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1450
Insights into the blood, gut, and oral microbiomes in Chinese patients with myocardial infarction: a case-control study
Published 2025-04-01“…Differential analyses were conducted to find key differential microbiota for MI. …”
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1451
Single-cell technology reveals the crosstalk between tumor cells and immune cells: driving immune signal transduction and inflammation-mediated cardiac dysfunction in the tumor mic...
Published 2025-08-01“…Functional validation encompassed siRNA knockdown, qRT-PCR, Western blot analysis, and cellular assessment in CRC cell lines.ResultsWe discovered four categories of tumor cells exhibiting variations in cell cycle, stemness, and differentiation. …”
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1452
Clinical characteristics of obsessive-compulsive disorder comorbid with obsessive -compulsive personality disorder: subtype implications
Published 2025-07-01“…BackgroundObsessive-compulsive disorder (OCD) is a psychiatric condition characterized by persistent obsessions and compulsions that lead to significant distress and functional impairment. Obsessive-compulsive personality disorder (OCPD) frequently co-occurs in individuals with OCD and has been identified in several studies as the most prevalent personality disorder within this population. …”
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1453
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1454
Multiomic characterization, immunological and prognostic potential of SMAD3 in pan-cancer and validation in LIHC
Published 2025-01-01“…Our study encompassed a comprehensive analysis of the following aspects: differential SMAD3 expression and its association with prognosis across diverse cancer types, gene mutations, immune cell infiltration, single-cell sequencing analysis, DNA methylation patterns, and drug sensitivity profiles. In vitro experiments were conducted with the primary objective of appraising both the expression profile and the precise functional attributes of SMAD3 within the milieu of Liver Hepatocellular Carcinoma (LIHC). …”
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1455
Sensory Dysfunction in ALS and Other Motor Neuron Diseases: Clinical Relevance, Histopathology, Neurophysiology, and Insights from Neuroimaging
Published 2025-02-01“…<b>Background</b>: The clinical profiles of MNDs are dominated by inexorable motor decline, but subclinical proprioceptive, nociceptive and somatosensory deficits may also exacerbate mobility, dexterity, and bulbar function. While extra-motor pathology and frontotemporal involvement are widely recognised in motor neuron diseases (MNDs), reports of sensory involvement are conflicting. …”
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1456
Meta-analysis of muscle transcriptome data identifies key genes influencing intramuscular fat content in pigs
Published 2025-08-01“…To identify key genes affecting IMF content, we performed a meta-analysis of the differential expression results from the 10 datasets using MetaVolcanoR. Subsequently, we conducted protein-protein interaction network analysis, Gene Ontology and Kyoto encyclopedia of genes and genomes functional enrichment analysis, and quantitative trait locus (QTL) analysis on the DEGs. …”
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1457
Integrated Cytological, Physiological, and Comparative Transcriptome Profiling Analysis of the Male Sterility Mechanism of ‘Xinli No.7’ <i>Pear</i> (<i>Pyrus</i> sp.)
Published 2025-06-01“…Comparative transcriptomics identified 283 co-expressed differentially expressed genes (DEGs). Functional enrichment linked these DEGs to ROS-scavenging pathways: galactose metabolism, ascorbate and aldarate metabolism, arginine and proline metabolism, fatty acid degradation, pyruvate metabolism, and flavonoid biosynthesis. qRT-PCR validated the expression patterns of key DEGs in these pathways. …”
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1458
Identification and Immunological Characterization of Cuproptosis Related Genes in Preeclampsia Using Bioinformatics Analysis and Machine Learning
Published 2025-01-01“…We identified 10 DECRGs conducted Gene Ontology (GO) function, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses, and a protein–protein interaction (PPI) network. …”
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1459
Exploring hematological diversity, a comprehensive study of CBC variations among the population of Tehsil Kot-Momin Sargodha
Published 2024-11-01“… Objectives: To ascertain the diversity and patterns observed in the complete blood count within the population of Tehsil Kot-Momin , Sargodha. …”
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1460
Effects of Simulated Nitrogen Deposition on the Physiological and Growth Characteristics of Seedlings of Two Typical Subtropical Tree Species
Published 2025-07-01“…Amid global environmental change, the intensification of nitrogen (N) deposition exerts critical impacts on the growth of forest vegetation and the structure and function of ecosystems in subtropical China. However, the physiological and growth response mechanisms of subtropical tree species remain poorly understood. …”
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