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1381
Identification of Critical Signature in Post‐Traumatic Stress Disorder Using Bioinformatics Analysis and in Vitro Analyses
Published 2025-01-01“…Weighted gene co‐expression network analysis (WGCNA) was employed to examine gene correlation patterns. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses were performed for functional annotation and enrichment analysis, respectively. …”
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1382
Genome-Wide Identification of the GRAS Transcription Factor Family in <i>Medicago ruthenica</i> and Expression Analysis Under Drought Stress
Published 2025-01-01“…Overall, this study analyzed the phylogenetic relationships, conserved domains, <i>cis</i>-regulatory elements and expression patterns of the <i>GRAS</i> gene family in <i>M. ruthenica</i>, filling the gap in the identification of the <i>MrGRAS</i> gene family and laying the foundation for functional analysis of the <i>MrGRAS</i> gene family.…”
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1383
Modeling Navigator Awareness of COLREGs Interpretation Using Probabilistic Curve Fitting
Published 2025-05-01“…This study models navigator awareness as a probabilistic function of encounter angle, aiming to identify interpretive transition zones and cognitive uncertainty in rule application. …”
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1384
A Temporal Convolutional Network–Bidirectional Long Short-Term Memory (TCN-BiLSTM) Prediction Model for Temporal Faults in Industrial Equipment
Published 2025-02-01“…The TCN layer incorporates batch normalization, an optimized activation function (Leaky ReLU), and a dropout mechanism to enhance its ability to capture multi-scale temporal features. …”
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1385
Microbial diversification is maintained in an experimentally evolved synthetic community
Published 2024-11-01“…We further observed loss-of-function mutations in flagellar genes that were fixed in monocultures but not in co-cultures. …”
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1386
Topologically Optimized Anthropomorphic Prosthetic Limb: Finite Element Analysis and Mechanical Evaluation Using Plantogram-Derived Foot Pressure Data
Published 2025-04-01“…During the development of conventional prosthetics, several challenges have been observed regarding the functional limitations, the restricted degrees of freedom compared to an actual human limb, and the biocompatibility issues between the surface of the prosthetic limb and the human tissue or skin. …”
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1387
Trends and key contributors in peripheral nerve regeneration research: A bibliometric study
Published 2025-06-01“…A bibliometric analysis was conducted to provide a structured overview of research trends, intellectual impact, and evolving themes in peripheral nerve regeneration. …”
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1388
Quantitative study on contribution of dynamic imbibition to oil production during fracturing and huff-n-puff in tight reservoirs
Published 2025-03-01“…Laboratory physical simulation experiments were carried out using natural tight conglomerate reservoir cores, utilizing a high-temperature and high-pressure multi-functional core displacement system and a high-temperature and high-pressure online displacement nuclear magnetic resonance imaging system. …”
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1389
Unraveling the molecular mechanisms of paclitaxel in high-grade serous ovarian cancer through network pharmacology
Published 2025-05-01“…Functional enrichment analysis was conducted using Gene Ontology and the Kyoto Encyclopedia of Genes and Genomes. …”
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1390
Promoting Resilience in Youth through Mindfulness mEditation (PRYME): Study protocol for a randomized controlled trial investigating the effects of mindfulness training as add-on t...
Published 2025-02-01“…Secondary outcomes include measures of self-compassion, rumination, experiential avoidance, and well-being. In addition, (functional) magnetic resonance imaging and computerized cognitive tasks are conducted at baseline and at end of treatment. …”
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1391
Tropical infections and the gut microbiome: dysbiosis, recovery, and clinical implications
Published 2025-08-01“…A structured literature search was conducted across PubMed, Scopus, and Web of Science, focusing on human GI microbiome dynamics, dysbiosis patterns, and recovery mechanisms in the context of tropical infectious diseases. …”
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1392
Near-source wastewater surveillance of SARS-CoV-2, norovirus, influenza virus and RSV across five different sites in the UK.
Published 2025-01-01“…Sites were selected for contrasting functions: an office, charity centre, museum, university, and care home. …”
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1393
Experimental study on modal analysis and vibration response of tunnel structures under different damage conditions due to subway train loads
Published 2025-01-01“…Then, using time-domain peak acceleration, frequency response function, frequency-domain modal frequency, and modal shape indicators, a detailed analysis of the tunnel’s dynamic response is conducted. …”
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1394
Life satisfaction in emerging adulthood: a longitudinal study of social support, resilience, and gender differences
Published 2025-07-01“…Psychological resilience was found to partially account for this association (indirect effect: β = 0.25, p < 0.001), suggesting that resilience may function as a linking factor between social support and subsequent wellbeing. …”
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1395
eQTL and multi-omics integration reveal PPIH as a prognostic and immunotherapeutic biomarker
Published 2025-08-01“…A comprehensive series of multi-omics bioinformatics analyses was subsequently conducted to assess the gene’s expression patterns, genomic alterations, prognostic relevance, and associations with the tumor microenvironment (TME) across various cancer types. …”
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1396
Multiomic analysis of the synthetic pathways of secondary metabolites in tobacco leaves at different developmental stages
Published 2025-06-01“…Despite substantial progress, the comprehensive regulatory landscape governing secondary metabolite biosynthesis during N. tabacum leaf development remains largely unclear.MethodsTo better understand the molecular regulatory mechanisms underlying the biosynthesis of secondary metabolites, particularly flavonoids, during N. tabacum leaf development, we conducted a transcriptomic and non-targeted metabolomic sequencing and analysis at three critical developmental stages: vigorous growth stage (T1), topping stage (T2), and harvest stage (T3).ResultsBased on our transcriptomic and metabolomic data, 25 unigenes exhibiting stage-specific expression patterns that were strongly associated with flavonoid accumulation were identified. …”
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1397
Molecular characteristics and cancer immunity of LRP1B and its relationship with the Hedgehog signaling pathway in colorectal cancer
Published 2025-03-01“…Immune cell infiltration and drug sensitivity analyses demonstrated that LRP1B plays a crucial role in immunotherapy and targeted therapy, suggesting that restoring LRP1B function could be a promising treatment strategy for CRC.ConclusionOur results indicate that LRP1B may function as a tumor suppressor factor in CRC, playing a significant role in mutation, therapy, and immune infiltration. …”
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1398
Genetic Alterations in War-Related Post-Traumatic Stress Disorder: A Systematic Review
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1399
Imaging of post-tuberculosis lung disease cases in children and adolescent survivors: a systematic review
Published 2025-12-01“…Post-TB patients may suffer from chronic respiratory symptoms, declining lung function, and persistent radiological abnormalities. …”
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1400
The Trehalose-6-Phosphate Synthase and Trehalose-6-Phosphate Phosphatase in Cocoa (Theobroma cacao L.): Genome-Wide Identification and Expression Analysis
Published 2025-03-01“…Detailed physicochemical characterization revealed significant variability in amino acid length, molecular weight, isoelectric point, and hydrophilicity among these proteins, suggesting functional diversity. Phylogenetic analyses, performed using the maximum likelihood method, classified the TcTPP family into three distinct clades and the TcTPS family into two main groups. …”
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