<i>Mycobacterium Ulcerans</i> Ulcer: Current Trends in Antimicrobial Management and Reconstructive Surgical Strategies by Bryan Lim, Omar Shadid, Jennifer Novo, Yi Mon, Ishith Seth, Gianluca Marcaccini, Roberto Cuomo, Daniel P. O’Brien, Warren M. Rozen

“…Surgical interventions in select cases are crucial, with timing being a significant factor in functional outcomes. The review also covers pediatric-specific challenges, including growth preservation and psychosocial support for young patients. …”
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Identification and Characterization of the OCT4 Upstream Regulatory Region in Sus scrofa by Seung-Hun Kim, Kwang-Hwan Choi, Dong-Kyung Lee, Mingyun Lee, Jae Yeon Hwang, Chang-Kyu Lee

“…However, the OCT4 promoter and four regulatory regions, including distal and proximal enhancer elements, had high similarity. Next, a functional analysis of the porcine OCT4 promoter region was conducted. …”
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Repetitive transcranial magnetic stimulation ameliorates chronic pain behavior and modulates the brain transcriptome in a mouse model of chronic constriction injury by Tianying Li, Guanwen Lin, Tao Zhang, Yani Guo, Yongjin He, Jing Luan, Jin Wang, Dan Lyu, Yiqi Weng, Xin Jin

“…Transcriptomic analysis revealed that CCI induced dysregulation of 66 genes, while rTMS partially normalized gene expression patterns. Functional enrichment analysis indicated significant involvement of pathways related to inflammatory responses, transporter activity, and ion channel regulation. …”
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Improving Fall Classification Accuracy of Multi-Input Models Using Three-Axis Accelerometer and Heart Rate Variability Data by Seunghui Kim, Jae Eun Ko, Seungbin Baek, Daechang Kim, Sungmin Kim

“…Reduced body movement and weakened musculoskeletal function as a result of aging increase the risk of falls and serious physical injuries requiring medical attention. …”
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A randomized, single-center double-blinded trial on the effects of diltiazem sustained-release capsules in patients with coronary slow flow phenomenon at 6-month follow-up. by Lun Li, Ye Gu, Tao Liu, Yupeng Bai, Lingbo Hou, Zhong Cheng, Liqun Hu, Bo Gao

“…Holter, liver and kidney function, treadmill exercise test, coronary angiography and left ventricular angiography were measured at baseline and after 6 months. …”
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Enhancing Fake Review Detection Using Linguistic Exaggeration, BERT Embeddings, and Fuzzy Logic by Mohammed Ennaouri, Ahmed Zellou

“…Our method first preprocesses reviews and extracts key linguistic features based on extravagant words using a fuzzy logic-based membership function that highlights extreme linguistic patterns. …”
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Using social-network analysis to map institutional actors’ links with vulnerable municipalities under climate change in Honduras’ dry corridor. Pathways towards improved cooperatio... by Carlos Eduardo Gonzalez-Rodriguez, Irma Ayes-Rivera, Jean-Francois Le Coq, Rafael Renteria-Ramos, Johana Marcela Castillo-Rivera

“…This research analyzes how institutional structures function and interact as a network to investigate the spatial coherence and relevance of public- and private-sector interventions related to agriculture, climate change, and food security in 153 municipalities of Honduras’ dry corridor. …”
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Knowledge Structure and Emerging Trends of Mild Cognitive Impairment with Dyssomnias in Recent 20 Years: A Bibliometric Analysis via CiteSpace and VOSviewer by Haoyu Huang, Zesen Zhuang, Yiwen Wan, Jiao Shi, Xu Yuan, Dan Wang, Shangjie Chen

“…Sleep plays a pivotal role in cognitive function, with dyssomnias not only exacerbating cognitive and affective symptoms associated with neurodegenerative diseases but also contributing to disease progression. …”
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Lung microbiome alterations correlate with immune imbalance in non-small cell lung cancer by Jiuling Cheng, Huaqi Wang

“…The association between microbial abundance and tumor stages, metastasis or not, nodule size, PD-L1 expression, as well as Ki-67 levels was conducted. Mann-Whitney tests were used to evaluate differences in the systemic immune-inflammation index (SII), T cell subsets (CD3+, CD4+, CD8+), as well as the CD4+/CD8+ ratio between different microbial expression patterns of Prevotella and Veillonella.ResultsSignificant β-diversity differences were observed between the tumor-bearing and contralateral normal lungs in individuals diagnosed with lung carcinoma. …”
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Optimizing Screw Fixation in Total Hip Arthroplasty: A Deep Learning and Finite Element Analysis Approach by Jacob Stroud, Emily T. Yan, Jacob Anthony, Kyle Walker, Chung-Hyun Goh

“…Total hip arthroplasty (THA) is a widely performed procedure to restore hip function in patients with degenerative joint diseases. …”
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Survey on the development of mimic defense in cyberspace:from mimic concept to “mimic+” ecology by Hailong MA, Liang WANG, Tao HU, Yiming JIANG, Yanze QU

“…Build upon the dynamic-heterogeneous-redundant architecture for multi-body execution, multi-mode ruling and multi-dimension reconstruction, cyberspace mimic defense (CMD) uses uncertain system to deal with the uncertain threat to cyberspace ubiquity.The evolution of CMD over the past 8 years were reviewed systematically from the vertical, horizontal, current, developing and future perspectives.From the vertical perspective, the development process of CMD from concept to theory and practice was summarized.From the horizontal view, it elaborated the core structure DHR (dynamical heterogeneous redundancy) of CMD, the principles based on CMD’s three major theorems, safety gains and performance costs.A comparison was conducted between CMD and five other active defense technologies, namely intrusion tolerance, moving target defense, zero trust architecture, trusted computing and computer immunology.From the current perspective, it reviewed the implementation elements, performance, system architecture, heterogeneous strategies, scheduling strategies, voting strategies and other common technology patterns and characteristics of 11 types of main existing mimic products including mimicry router, mimicry processor, mimicry DNS server and mimicry cloud platform.From the developing perspective, it explored the “mimic+” AICDS (Mimic + AI/IoT/Cloud/Data/SDN) symbiotic ecology with respect to 5 types of new technologies, namely artificial intelligence, Internet of things, cloud computing, big data and software-defined network, and proposed the corresponding technology junctions and cross research value.From the future perspective, it looked into the future mimicry baseline 2.0 product ecology, “mimic +5G/6G”, “mimic + edge computing”,“mimic + cloud” and “mimic + blockchain” application scenarios.Besides, 4 types of challenges faced by CMD in the future were analyzed and summarized, including escape space of multi-mode decision attack, mutual restriction of heterogeneous and synchronous, difficult balance between security and function, and limited transformation space of existing endogenous security components.…”
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Comparative transcriptome analysis of PBMCs in cats diagnosed with and recovered from FIPV by Ju Young Lee, Hyeong Ryeol Cho, Hong-Geun Oh, Jeong Ho Hwang

“…Additionally, we observed that kruppel-like factor 6 (KLF6) and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) were upstream molecules of IL-8, promoting neutrophil activation and function. Conclusions This study identified immunological alterations in PBMCs of Normal, FIPD, and FIPR cats. …”
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University-based physical education as a structured temporal and spatial opportunity for shaping health-oriented lifestyles by Lu Zhang, Tao Zhong, Kui Dong

“…BackgroundRegular physical activity is widely recognized for its health benefits, including improved cardiovascular function and reduced risk of chronic diseases. However, insufficient physical activity remains prevalent among university students, many of whom fail to meet recommended guidelines. …”
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Left Heart Changes in Hypertensives Attending Rivers State University Teaching Hospital: An Echocardiographic Review by Ngozi CS, Deinma A, Rita W, Bonas H

“…Hypertensive heart disease refers to the complex and diverse change of the cardiac structure and function secondary to hypertension. Objective: This study aims to investigate the patterns and gain insight to the progression of cardiac changes among hypertensives patients presenting at the Rivers State University Teaching Hospital, Port Harcourt. …”
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Between reciprocity and agrarian transformation: Challenges to land tenancy and labor relations among rice-farming communities in Lahat Regency, South Sumatra Province, Indonesia by Septri Widiono, Jheni Juwita Sari Melia, Ketut Sukiyono, Bembi Akbar Serawai

“…However, they reveal underlying tensions between tradition and social transformation, in which evolving reciprocity practices may increasingly function as mechanisms of surplus accumulation under market penetration. …”
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Awareness of Menstrual Abnormalities among Female Nursing Students at the University of Sulaimani by Peshwaz Abdulrahman Ahmad, Amani Fadhil Abbas, Nazera Salam Mena Qadir

“…Background: The menstrual cycle, which occurs on a monthly basis from menarche to menopause and facilitates fertilization and conception, is a normal function in the female reproductive system. A 28-day cycle is the typical length. …”
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Integrated multi-omics analysis identifies TPX2 as a potential prognostic and immunological biomarker in hepatocellular carcinoma by Hui Peng, Yong-peng Wei, Xin-bo Liu, Yu Wang, Jian-yong Yuan

“…Methods: We conducted an integrated multi-omics analysis using transcriptomic (TCGA, GTEx, GEO), proteomic (CPTAC), and pharmacogenomic (GDSC, PRISM, CTRP) datasets to assess TPX2 expression patterns in HCC. …”
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Atypical early neural responses to native and non-native language in infants at high likelihood for developing autism by Lauren Wagner, Megan Banchik, Tawny Tsang, Nana J. Okada, Rebecca Altshuler, Nicole McDonald, Susan Y. Bookheimer, Shafali S. Jeste, Shulamite Green, Mirella Dapretto

“…Methods In this study, we used functional magnetic resonance imaging (fMRI) to examine differences in language processing in 9-month-old infants at high (HL) and typical (TL) familial likelihood for ASD. …”
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DHCR24 overexpression is involved in lipid metabolic reprogramming to drive cervical cancer malignant progression and is associated with immune microenvironment by Lin Cheng, Yuance Xu, Zhuo Li, Danting Sun, Yan Xu, Junqi He, Yulong Chen, Qin Yao

“…A prognostic nomogram incorporating tumor stage and DHCR24 expression levels was developed to predict clinical outcomes in patients. Functional studies using SiHa cell lines were conducted to elucidate the oncogenic properties of DHCR24. …”
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Genomic features, antimicrobial resistance and pathogenicity assessment of Escherichia coli serotype O177:H51 strain JS01 isolated from a diseased chicken by Lunbin Xia, Guanglei Wang, Naidong Chen, Deliang Qiao, Jianwen Cao, Shaoshuai Bi

“…To elucidate its multi-drug resistance and pathogenic mechanisms, whole-genome sequencing (WGS) of JS01 was performed, followed by functional gene annotation, sequence typing, and serotype analysis. …”
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