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1321
Comprehensive multi-omics characterization of different cuts of Dezhou donkey meat
Published 2025-12-01“…This study presents an in-depth analysis of meat quality traits and gene expression patterns across various donkey meat cuts, highlighting the key functional genes involved. …”
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1322
Harnessing the diversity of a lettuce wild relative to identify anthocyanin-related genes transcriptionally responsive to drought stress
Published 2025-01-01“…Some wild variants had high or moderate predicted impacts on the respective protein function: a transcription factor that responds to abiotic stresses, a heat shock protein involved in stomatal closure, and a phospholipase participating in anthocyanin accumulation under abiotic stress. …”
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1323
The impact of shelter-in-place during the COVID-19 pandemic on social support for mental health recovery: A prescribing-oriented qualitative study of patient perspectives.
Published 2025-01-01“…For the second category of themes, specific functions of social relationships identified included those centered around (a) instrumental support, (b) emotional support, (c) community connection. …”
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1324
The revival of the electrocardiogram in the stress imaging era: what European Society of Cardiology 2024 guidelines say (and don’t say)
Published 2025-05-01“…An ECG continuously monitors the heart’s electrical signals, capturing data on heart rate, rhythm, and electrical conduction patterns. The value of the ECG in this context lies in its ability to detect ischemic changes, which occur when there is insufficient blood flow to the heart muscle due to narrowed or blocked coronary arteries, but also for coronary vasospasm or coronary microvascular disease. …”
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1325
Identification of hub genes in myocardial infarction by bioinformatics and machine learning: insights into inflammation and immune regulation
Published 2025-06-01“…These genes were then subjected to functional enrichment analysis, including Kyoto Encyclopedia of Genes and Genomes (KEGG), Gene Ontology (GO), and Gene Set Enrichment Analysis (GSEA). …”
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1326
Circulating Plasma Proteins as Biomarkers for Immunotherapy Toxicity: Insights from Proteome-Wide Mendelian Randomization and Bioinformatics Analysis
Published 2025-07-01“…Circulating plasma proteins, dynamically accessible and functionally linked to immunity, may predict and offer novel targets for irAEs. …”
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1327
Exploration of biomarkers associated with histone lactylation modification in spinal cord injury
Published 2025-07-01“…Inter-cluster comparisons were conducted to examine Hallmark pathways, HLA genes, and immune functions. …”
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1328
Expressing the Author's Position in the English-Language Network Film Review
Published 2021-12-01“…The authors proceed from the position that the methods of subject verbalization are determined by functional characteristics of discourse. The relevance of the study is due to the interest of modern linguistics in the study of the subject factor in “personal” types of discourse. …”
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1329
Single-Nucleus RNA Sequencing Reveals Muscle-Region-Specific Differences in Fibro-Adipogenic Progenitors Driving Intramuscular Fat Accumulation
Published 2025-03-01“…Background: Ectopic fat deposition refers to lipid accumulation that affects metabolic function and tissue characteristics. Japanese Black cattle are distinguished by their high intramuscular fat content, which contributes to their distinctive character. …”
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1330
WFDC3 identified as a prognostic and immune biomarker in pancreatic cancer
Published 2025-05-01“…To address this, we conducted an initial investigation using comprehensive bioinformatic analyses to evaluate WFDCs expression patterns across multiple tumor types, with a focus on PAAD. …”
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1331
Effects of water and fertilizer management on soil bacterial communities, enzyme activities, and nutrient availability in greenhouse tomatoes.
Published 2025-01-01“…Microbial communities under I2 (PCo1 = 11.13%) showed greater homogeneity while preserving treatment-specific patterns, suggesting slight deficit irrigation balances stability and functional differentiation. …”
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1332
Effectiveness of Cognitive Behavioral Therapy in Managing Painful Temporomandibular Joint Disorders -A Systematic Review of Randomized Clinical Studies
Published 2025-12-01“…One study reported that CBT might enhance function recovery in myofascial pain patients with limited opening and posture correction.Conclusion The study analysis suggested CBT may reduce damaging thought patterns and cognitive difficulties and be used with the standard treatment of TMDs. …”
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1333
The role of the mitochondrial dynamic distribution in oocyte development arrest induced by F-53B
Published 2025-09-01“…Phenotypic assessments included oocyte maturation status, spindle architecture, and mitochondrial function, and single-cell transcriptomic analysis was conducted to investigate molecular mechanism. …”
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1334
Light in the Darkness: Responses to Light and Diel Activity Rhythm in an Eyeless Cave Flatworm (Dendrocoelum italicum)
Published 2025-06-01“…Although cave adaptation and eye absence generally imply the loss of capability to perceive light, several cave‐adapted species have retained this function, showing some degree of phototaxy or rhythmicity. …”
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1335
Pan-cancer analysis reveals dual roles of HES6 in cancer immunity and prognosis
Published 2025-06-01“…Abstract A comprehensive pan-cancer analysis of HES6 was conducted to investigate the differential expression patterns, clinical implications, and prognostic significance of HES6 across multiple cancer types, while also aiming to elucidate the underlying biological mechanisms of HES6 in oncogenesis. …”
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1336
Prognostic Potential of AKR1B1 in triple-negative breast cancer
Published 2025-01-01“…This research conducts a thorough bioinformatics examination to explore the possible function of Aldose Reductase (AKR1B1) in Triple - Negative Breast Cancer (TNBC). …”
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1337
Genome-Wide Identification of the <i>GS3</i> Gene Family and the Influence of Natural Variations in <i>BnGS3-3</i> on Salt and Cold Stress Tolerance in <i>Brassica napus</i>
Published 2025-04-01“…Our research results aim to provide insights into the function and molecular mechanisms of <i>BnGS3-3</i> in <i>Brassica napus</i>, and to offer valuable genetic resources for molecular breeding to improve salt and low-temperature tolerance in <i>Brassica napus</i>.…”
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1338
Genome-wide identification of cyclic nucleotide-gated channel gene family in Solanum tuberosum and silencing of StCNGC2 provides resistance to Pectobacterium carotovorum
Published 2025-07-01“…Expression patterns were examined in different tissues and under stress conditions. …”
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1339
A comprehensive transcriptome based meta-analysis to unveil the aggression nexus of oral squamous cell carcinoma
Published 2025-06-01“…However, the drivers of this aggressive phenotype remain unclear due to the variability in gene expression patterns. To address this, an integrative meta-analysis of six publicly available transcriptomic profiles, categorized by lymph nodal status, is conducted. …”
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1340
Bioinformatic Insights and XGBoost Identify Shared Genetics in Chronic Obstructive Pulmonary Disease and Type 2 Diabetes
Published 2025-03-01“…A multifaceted bioinformatics approach, encompassing the limma R package, unified matrix analysis, and weighted gene co‐expression network analysis (WGCNA), was deployed to identify differentially expressed genes (DEGs) and hub genes. Functional enrichment and protein–protein interaction (PPI) analyses were conducted, followed by cross‐species validation in Mus musculus models. …”
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