Diagnosis and treatment principle in Sasang medicine: original symptom by Seungwon Shin, Yun-Hee Kim, Min-Woo Hwang

“…It is the key factor in the clinical application of Sasang medicine including the diagnosis of constitutional type and Sasang symptomatology because the imbalance of metabolic functions of each Sasangin originates from that. The working principles of the OS and Sasang symptomatology can be summarized as follows. …”
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Age modulates, religious coping mediates: the role of attitude to self in cancer patients’ quality of life by Maria-Chidi C. Onyedibe, Runcie C.W. Chidebe, Runcie C.W. Chidebe, Runcie C.W. Chidebe, Barbara L. Andersen, Uzoamaka F. Ugwoke, Lawrence Ejike Ugwu, Lawrence Ejike Ugwu

“…Mediation and moderation analyses were conducted using SPSS (Version 29) and SmartPLS (Version 4).ResultsNegative generalization (β = −0.25, p < 0.001) and self-criticism (β = −0.19, p < 0.001) reduced physical well-being, while high standards positively influenced emotional well-being (β = 0.27, p < 0.001) but negatively impacted functional well-being (β = −0.13, p < 0.01). …”
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Unraveling the laser decal transfer-based printing of ZnO ceramic towards FEP-ZnO-based Piezo-Tribo hybrid nanogenerators by Arpit Kumar Singh, Anshu Sahu, Palani Iyamperumal Anand

“…This phase change often alters the chemical and functional properties of the devices, highlighting the need for a fabrication method that preserves the original material characteristics. …”
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Topographical Organization of Prefrontal Cortex and Adjacent Areas Projections to the Dorsomedial Caudate–Putamen in Rats: A Retrograde Tracing Study by Christopher L. Robison, Theodore Kazan, Rikki L. A. Miller, Tyler Allen, Jason S. Hensley, Sergios Charntikov

“…These findings provide a comprehensive map of the topographical organization of cortical inputs to the dmCPu, highlighting differential connectivity patterns that may underlie distinct functional roles in goal-directed and habitual behaviors. …”
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Sensitivity analysis of activity scheduling parameters with a parameter optimization framework by Matheus Moro Zamprogno, Domokos Esztergár-Kiss

“…The relevant parameters, activity chains, transport modes, optimization algorithms, and fitness functions, are identified and considered. For each parameter, an investigation is conducted to reveal its behavior throughout the runs. …”
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Targeting Cancer with Paris’ Arrow: An Updated Perspective on Targeting Wnt Receptor Frizzled 7 by Kieran Hodson, Hector M. Arredondo, William E. Humphrey, Dustin J. Flanagan, Elizabeth Vincan, Karl Willert, Helen B. Pearson, Toby J. Phesse

“…Additionally, we present new figures generated by our group using the publicly available Pan-Cancer Atlas RNAseq datasets, highlighting FZD7 expression patterns in patient samples. This integrated approach aims to provide updated insights into the function of FZD7 during cancer and its growing status as an attractive target for therapy. …”
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Transcriptome-wide identification and systematic analysis of the Retrotransposon genes and their roles in ginsenoside biosynthesis in Panax ginseng by Chaofan Wang, Ruicen Liu, Dinghui Wang, Li Li, Yue Jiang, Yanfang Wang, Kangyu Wang, Mingzhu Zhao, Yi Wang, Meiping Zhang

“…Results 1,301 Retrotransposon genes were identified in ginseng transcriptome using bioinformatics methods, and a systematic analysis was conducted on their gene structures, phylogenetic relationships, and expression patterns. …”
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Multi‐omics profiling identifies TNFRSF18 as a novel marker of exhausted CD8⁺ T cells and reveals tumour‐immune dynamics in colorectal cancer by Tengfei Jia, Yingxi Guo, Xin meng Cheng, Zeyang Zhou, Xiaojiang Xu, Hebin Liu, Xiaodong Yang

“…T cell exhaustion markers, immune clonality, gene expression profiles, and the spatial distribution of both tumour cells and immune cells were systematically profiled. Functional enrichment and intercellular communication analyses were conducted. …”
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Comprehensive bioinformatics analysis of MEX3 family genes in hepatocellular carcinoma by Xuezhong Zhang, Peng Sun, Tingting Chu, Yuling Feng, Xuebin Zhang

“…This study aims to systematically analyze the expression patterns, prognostic significance, and immune-related functions of MEX3A, MEX3B, MEX3C, and MEX3D in HCC using comprehensive bioinformatics approaches. …”
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Clinical Molecular Immunohistochemistry Mismatch Repair Mutations in Lynch Syndrome in Patients Under 50 Years: A Systematic Review by Bogdan Adrian Manta, Adrian Cosmin Ilie, Felicia Marc, Daciana Nistor, Patricia Octavia Mazilu, Claudia Borza

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Case Report: Arthroscopic treatment of cedell fracture, shepherd fracture, and avulsion fracture at the insertion of the calcaneofibular ligament by Sitong Zhang, Dejian Li, Qian Wang

“…Surgical procedures in this area are rare, and inadequate treatment may lead to significant discomfort and limitations in daily functioning for patients. In this case report, we describe a 45-year-old male who experienced a fall from a 2-meter height, leading to persistent right ankle swelling for 6 days. …”
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The Portal to a Magic World. An Alternative Model of Introduction to Art by Ushkarev Alexander A.

“…However, the later this process begins, the more difficult it is, and the more effort may be required to catch up. This pattern is explained in P. Bourdieu’s theory of cultural capital and has been repeatedly confirmed by empirical studies on art audiences conducted in Russia and abroad. …”
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The role of microbiomes in animal invasions: a scoping review by Claudia Romeo, Elsa Brenner, Lucas A. Wauters, Antton Alberdi

“…We conducted a scoping review of studies focusing on microbiomes and animal invasions to explore the extent and nature of research efforts on this topic and to identify general patterns that may help elucidate the relationship between host microbial communities and invasiveness. …”
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Latent profile analysis of health-related quality of life and its associated factors in postoperative aortic dissection patients: a cross-sectional study by Wanbing Huang, Qiansheng Wu, Yufen Zhang, Hongmei Zhu

“…The patients were divided into three HRQOL subgroups: “high psychological distress-pain group” (29.0%), “mild functional impairment-anxiety group” (49.3%), and “mild functional impairment-adaptation group” (21.6%). …”
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Early outcome of femoral supracondylar fracture managed with distal femoral locking plate at National Orthopaedic Hospital Dala Kano by Tsoho SA, Abubakar K, Awomusi FO, Usman MI, Muhammad S

“… Background: Supracondylar fractures of the femur cause considerable morbidity and mortality especially in the elderly.1 The incidence was found to be higher among the younger socioeconomically active groups.1 Surgical treatment of this difficult fracture is a challenge due to the need for anatomic and functional restoration of the fracture fragments. …”
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Morphological Seed Traits Structure Relationships Between Biocrusts and Plant Emergence by J. Bacovcin, C. McIntyre, C. A. Havrilla

“…As such, biocrusts can have substantial effects on plant emergence depending on plant origin, functional group, and biocrust characteristics. However, understanding of possible mechanisms underlying these variable effects remains limited. …”
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Geochemical and hydrocarbon generation evolution characteristics of marine-continental transitional facies shale: a case study of the Lower Permian Shanxi Formation in the Daning-J... by Yangyang ZHANG, Yong LI, Xueying ZHANG, Liyuan LUO, Qingbo HE, Shuxin LI, Xiangjun LIU, Xiang LI, Xingtao LI, Qiang YANG, Shijia CHEN, Jungang LU, Nan ZHANG, Zhe LIU, Ruiyang YU, Haichuan MA

“…For C1-5, the two peaks of activation energy were 56 kcal/mol (28.45%) and 61 kcal/mol (19.18%), with a frequency factor of 2.2×1011 S-1. (4) The variation trend between cumulative gas production rate and Ro for the marine-continental transitional facies shale in the Shanxi Formation followed the pattern of a logistic function described by y=1/(1+e-x). …”
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Enhanced fibrotic potential of COL1A1hiNR4A1low fibroblasts in ischemic heart revealed by transcriptional dynamics heterogeneity analysis at both bulk and single-cell levels by Cheng Luo, Cheng Luo, Cheng Luo, Baoping Tan, Luoxiang Chu, Liqiang Chen, Xinglong Zhong, Yangyang Jiang, Yuluan Yan, Fanrui Mo, Hong Wang, Fan Yang, Fan Yang

“…The activity of gene sets related to progressive fibrosis was quantified for each FB cluster using the AddmoleculeScore function. Differentially expressed genes (DEGs) for the specific cell cluster with the highest fibrotic transcription dynamics were identified and integrated with bulk RNA sequencing data for analysis. …”
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Transcriptomic analysis of mammary gland tissues in lactating and non-lactating dairy goats reveals miRNA-mediated regulation of lactation, involution, and remodeling by Yanan Peng, Xinhua Duan, Linfan Zhang, Yiyi Guo, Jinlin Cao, Weiping Ao, Rong Xuan

“…Differential expression analysis, miRNA clustering, Gene Ontology (GO) annotation, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment were performed to predict the functions of target genes. A miRNA-mRNA regulatory network associated with mammary gland development was constructed, and functional validation experiments were conducted to confirm key regulatory relationships.ResultsA total of 1,120 miRNAs were identified, including 408 known and 712 newly predicted miRNAs. …”
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Unveiling the role of coagulation-related genes in acute myeloid leukemia prognosis and immune microenvironment through machine learning by Liyun Ji, Yanxia Yang, Siyue Ma

“…We further identified differentially expressed genes (DEGs) between groups and conducted functional enrichment analyses. Additionally, a prognostic model was constructed using machine learning techniques, and its prognostic ability was validated. …”
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