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921
Diffusion–tensor MRI study of the relationship between glymphatic system asymmetry and onset lateralization in Parkinson’s disease
Published 2025-07-01“…This study demonstrated that PD patients with lateralized motor symptom onset exhibit different patterns of glymphatic system function. The glymphatic system asymmetry may provide new insights into the mechanism underlying the lateralized onset of PD.…”
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922
Identification and Characterization of SQUAMOSA Promoter Binding Protein-like Transcription Factor Family Members in <i>Zanthoxylum bungeanum</i> and Their Expression Profiles in R...
Published 2025-02-01“…This study will help us gain a deeper understanding of the functions of <i>ZbSPLs</i> and lay a genetic foundation for future breeding of high-quality, highly abiotic resistant varieties of <i>Z. bungeanum</i>.…”
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923
The transcription factor PbeNAC83 positively regulates the Valsa canker resistance in apple and pear
Published 2025-08-01“…PbeNAC83 was transfected into the DuliG03 suspension cells, and three wellgrown overexpression cell lines were obtained. Functional analysis demonstrated that PbeNAC83-OE cells were more resistant to Vp and VpM compared to the control. …”
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924
Deciphering ovarian cancer heterogeneity through spatial transcriptomics, single-cell profiling, and copy number variations.
Published 2025-01-01“…At the cellular level, single-cell RNA sequencing (scRNA seq) analysis identified three meta-programs that delineate the functional profile of tumor cells. The communication networks between tumor cell clusters exhibited unique patterns associated with the meta-programs governing these clusters. …”
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925
Study on salt deposition distribution and environmental effect of seawater cooling tower
Published 2025-04-01“…Abstract A three-dimensional numerical simulation model was developed to examine the dispersion and migration of droplets in large, naturally ventilated seawater cooling towers, as well as the pattern of salt deposition influenced by nearby buildings and crosswinds. …”
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926
Single-Cell RNA sequencing reveals mitochondrial dysfunction in microtia chondrocytes
Published 2025-01-01“…Chondrocytes from microtia samples showed lower mitochondrial function scores compared to normal samples. Trajectory analysis revealed more disorganized differentiation patterns in microtia chondrocytes. …”
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927
Interplay of a non-conjugative integrative element and a conjugative plasmid in the spread of antibiotic resistance via suicidal plasmid transfer from an aquaculture Vibrio isolate...
Published 2018-01-01“…Tn6283 is unusual among integrative elements in that it apparently does not encode transfer function and its excision barely generates unoccupied donor sites. …”
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928
Upper Limb Neural Tension Test and Spinal Biomechanics: Insights from a Longitudinal Pilot Study
Published 2025-05-01“…<b>Background:</b> The Upper Limb Neural Tension Test (ULNTT) is a common assessment for neurodynamic function, yet the relationship between ULNTT findings and specific spinal biomechanical patterns remains poorly understood, particularly in the context of cervicobrachial neuralgia. …”
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929
Numerical-based theoretical investigation on the thermal efficiency of viscoplastic fluid suspended with ternary nanoparticles using the finite element approach
Published 2025-09-01“…Linear shape and weight functions are used in related weak forms. Galerkin approximations are substituted in residuals, and stiffness elements are derived. …”
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930
Isokinetic Evaluation of Quadriceps and Hamstring Muscle Performance in the Rehabilitation Phase after ACL Reconstruction
Published 2025-06-01“…Subgroup analyses were conducted based on sex and athletic background to explore differences in muscle performance and recovery patterns.…”
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931
Common and distinct neural underpinnings of the association between childhood maltreatment and depression and aggressive behavior
Published 2025-01-01“…First, we employed Network-Based Statistics (NBS) on resting-state functional magnetic resonance imaging (fMRI) data to identify functional connectivity (FC) patterns associated with depression and aggression. …”
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932
Economic growth and urban metamorphosis: A quarter century of transformations within the metropolitan area of Bucharest
Published 2018-02-01“…Cities in developed countries of Western Europe and Asia experienced rapid economic growth during the second half of the 20th century and exhibited novel patterns of evolution in terms of urban form and associated functional characteristics. …”
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933
Surface crystal-orientation-dependent second-order nonlinear optical properties of cubic boron arsenide (c-BAs)
Published 2025-01-01“…The isotropic complex dielectric functions and the derived linear optical parameters have been obtained, such as complex refractive index and reflectivity. …”
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934
Neural dynamics of spontaneous memory recall and future thinking in the continuous flow of thoughts
Published 2025-07-01“…To address this gap, we conducted a functional magnetic resonance imaging study using a think-aloud paradigm, where participants verbalize their uninterrupted stream of thoughts during rest. …”
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935
Annual Variation Characteristics of Air Conditioning Operating Behavior and Its Impact on Model Application in Office Buildings
Published 2024-11-01“…Based on a dynamic model framework constructed with a three-parameter Weibull function and a time superposition function, this study conducted modeling and analysis of dynamic AC operating behaviors in the same open-plan office across different years. …”
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936
Multi-omic analyses reveal PTPN6’s impact on tumor immunity across various cancers
Published 2025-04-01“…We analyzed PTPN6 expression data from open access databases using various statistical techniques, including survival analysis, genetic heterogeneity analysis, immune profiling, single-cell analysis, drug sensitivity analysis, and protein interaction analysis. We also conducted in vitro experiments utilizing colorectal cancer cell lines to validate PTPN6’s functional role. …”
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937
Graphitic Carbon Nitride: A Novel Two-Dimensional Metal-Free Carbon-Based Polymer Material for Electrochemical Detection of Biomarkers
Published 2024-11-01“…Based on g-C<sub>3</sub>N<sub>4</sub>, electrochemical biosensors have provided better biocompatibility, higher sensitivity, low detection limits, nontoxicity, excellent selectivity, and surface versatility of functionalization for the delicate identification of target analytes. …”
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938
Low-frequency rTMS modulates small-world network properties in an AVH-related brain network in schizophrenia
Published 2025-04-01“…Resting-state fMRI data were collected before and after treatment to assess functional connectivity within the predefined 35-region AVH-related network. small-worldness (σ), normalized clustering coefficient (γ), and normalized characteristic path length (λ), as well as functional segregation (clustering coefficient [Cp], local efficiency [El]) and functional integration (global efficiency [Eg], characteristic path length [Lp])—were analyzed before and after rTMS. …”
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939
miR-34-5p mediates 20E-induced autophagy in the fat body of Bombyx mori by targeting Atg1
Published 2025-03-01“…Results We constructed six small RNA libraries using Bombyx mori fat body treated with 20E. Expression and functional analyses were conducted to identify 20E-responsive miRNAs. …”
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940
Construction and validation of acetylation-related gene signatures for immune landscape analysis and prognostication risk prediction in luminal breast cancer
Published 2025-07-01“…Mouse model was constructed for in vivo validation of KAT2B and TAF1L function. Results In our study, we utilized the TCGA-BRCA database to conduct a comprehensive analysis of the acetylation regulatory pattern in luminal breast cancer. …”
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