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861
Identification of genes related to fatty acid metabolism in type 2 diabetes mellitus
Published 2024-12-01“…Differential expression analysis, WGCNA, machine learning algorithms, diagnostic analysis, and validation were employed to identify key feature genes. Functional analysis, ceRNA network construction, immune microenvironment assessment, and drug prediction were conducted to explore the underlying molecular mechanisms. …”
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862
Comprehensive analysis of the circular RNA expression profile and circRNA–miRNA–mRNA network in the goat skin with divergent wool curvature
Published 2025-08-01“…However, the expression and function of circRNAs in the wool curvature of Zhongwei goats are unclear. …”
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863
Vibrotactile Feedback Strategies for Trunk-Stabilizing Exercises in a Home-Based Scenario: Qualitative Interview Study Among Physiotherapists
Published 2025-07-01“…For each exercise-specific motion pattern, it was recorded whether feedback was provided. …”
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864
Estimates on Age, Growth, Sex Composition, and Mortality of <i>Silurus lanzhouensis</i> (Chen, 1977) in the Upper Yellow River, China
Published 2025-07-01“…Further analysis of the length–weight relationships unveiled an allometric growth index (<i>b</i>) of 2.9562 for the overall samples, indicating an isometric growth pattern. Additionally, insights into the growth characteristics of <i>S. lanzhouensis</i> were provided by the von Bertalanffy growth function, revealing an asymptotic total length (<i>L<sub>∞</sub></i>) of 119.30 cm and a growth coefficient (<i>K</i>) of 0.1278 yr<sup>−1</sup>. …”
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865
Enhancing corrosion resistance of Al alloy sheets with potential gradient by arc-sprayed Zn coatings
Published 2024-11-01“…In contrast, the Zn coating, when exposed to a corrosive environment, demonstrated the beneficial cathodic effect as a sacrificial anode and the protective function of a passivating film, thus mitigating corrosion. …”
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866
Backgrounds of origin and character of structural changes in testicles of coalminers of Donbass region
Published 2014-04-01“…Purpose – to establish mechanisms of changes in morphological and functional states of testicles of coal miners by complex of qualitative and quantitative histological and immunohistochemical studies for further development of differential diagnostic criteria of verification of the Chernobyl impact factor on liquidators of CNPP accident. …”
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867
Range‐Wide Assessment of the Tasmanian Devil Gut Microbiome
Published 2025-05-01“…ABSTRACT The gut microbiome is an important component of host health and function and is influenced by internal and external factors such as host phylogeny, age, diet, and environment. …”
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868
Identification of MRS2 Gene Family and Expression Analysis in Response to Magnesium Treatment in <i>Malus domestica</i>
Published 2025-05-01“…These genes may become candidate genes for subsequent functional studies. This work will provide a basis for future research on the response mechanism and function of the MRS2 gene family in response to magnesium stress.…”
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869
The Role of Potassium and KUP/KT/HAK Transporters in Regulating Strawberry (<i>Fragaria</i> × <i>ananassa</i> Duch.) Fruit Development
Published 2025-07-01“…Transcriptomic profiling revealed the expression of 19 FaKUP genes within the fruit receptacle, with a predominant downregulation observed during ripening, particularly in <i>FaKUP14</i>, <i>24</i> and <i>47</i>. This pattern suggests their functional relevance in early fruit development and turgor maintenance. …”
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870
Clinical Phenotypes and Age-Related Differences in Presentation, Treatment, and Outcome of Heart Failure with Preserved Ejection Fraction: A Vietnamese Multicenter Research
Published 2021-01-01“…While Southeast Asia reported the highest mortality and morbidity among Asian population, little is known about the Vietnamese population, including patient characteristics, prescribing pattern and mortality rate. Methods. We conducted an observational study on 477 patients diagnosed with HFpEF from seven hospitals in Southern Vietnam from January 2019 to December 2019. …”
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871
Implementasi Teori Konstruksi Sosial dalam Penelitian Public Relations
Published 2006-06-01“…The answer for this question will indicate whether or onot PR performance has succeeded in fulfilling its functions among public. Adopting Berger and Luckmann perspective over the construction of social reality, a PR corporate will achieve a new level of existence by the process of habitualization involving an effective pattern of communication. …”
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872
Maternal plasma extracellular vesicles tsRNA as potential biomarkers for assessing preterm labor risk
Published 2025-05-01“…Transcriptomic sequencing was conducted to identify tsRNA1-mediated pathways, and DNA methylation patterns were predicted based on the transcriptomic data. …”
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873
PD1 blockade enhances K+ channel activity, Ca2+ signaling, and migratory ability in cytotoxic T lymphocytes of patients with head and neck cancer
Published 2020-10-01“…The purpose of this study was to elucidate the effects of pembrolizumab on potassium (K+) channel (KCa3.1 and Kv1.3) activity, Ca2+ fluxes, and chemotaxis in the cytotoxic T cells of patients with HNSCC and to determine their correlation with treatment response.Methods Functional studies were conducted in CD8+ peripheral blood T cells (PBTs) and tumor infiltrating lymphocytes (TILs) from patients with HNSCC treated with pembrolizumab. …”
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874
Uncovering Subclinical Cardiac Involvement in VEDOSS: An Echocardiographic Driven Study
Published 2025-02-01“…<b>Conclusions:</b> Careful monitoring of cardiac function in VEDOSS patients is crucial as subclinical alterations may occur even in the absence of symptoms. …”
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875
Canopy‐Mediated Dynamics of Moss Communities in Primary Succession: Coupling of N2‐Fixation and Biomass Accumulation in Subalpine Forests Following Glacial Retreat
Published 2025-07-01“…The effects of canopy cover and composition on moss productivity, photosynthesis, and N2‐fixation rates represent a dynamic set of canopy‐bottom layer interactions that may shape the structure and function of developing subalpine forest.…”
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876
Integrating Genomics and Molecular Biology in Understanding Peritoneal Adhesion
Published 2025-06-01Get full text
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877
Long Noncoding RNA GATA3-AS1 Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma by Suppression of PTEN, CDKN1A, and TP53
Published 2019-01-01“…However, the expression pattern and function of GATA3-AS1 in hepatocellular carcinoma (HCC) remain unknown. …”
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878
The Efficacy and Brain Network Mechanism of Acupuncture for Knee Osteoarthritis: A Study Protocol for Randomized Controlled Neuroimaging Trial
Published 2025-01-01“…Forty healthy subjects will be recruited for observation, with a single MRI scan conducted only at baseline (− 1– 0 week). The primary efficacy indicator will be the change in NRS score after four weeks of treatment, with secondary outcomes including WOMAC, STAI, and safety assessments. fMRI observations will employ independent component analysis, brain network construction, and functional connectivity, complemented by Pearson correlation analysis to explore the relationship between brain responses and clinical improvements.Conclusion: This study will initially uncover how acupuncture intervention for chronic KOA pain centrally regulates and exerts therapeutic effects through the modulation of abnormal brain network functional connectivity patterns, with a demonstrated long-term effect.Ethics and Dissemination: This study has been approved by the ethics committee of Shandong University of Traditional Chinese Medicine Affiliated Hospital ((2024) Lunshen No. (028) - KY).Clinical Trial Registration: This study has been approved by registered in the Chinese Clinical Trial Registry (ChiCTR2400083695).Keywords: acupuncture, knee osteoarthritis, neuroimaging, RCT, protocol…”
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879
Investigation of Sleep Hygiene and Quality of Life in Nursing Students
Published 2025-02-01“…The students’ SHI score average was 33.6 ± 6.2, and the SF36 scale sub-dimensions score were; physical function 91.5±12.5, physical role difficulty 67.7±34.9, emotional role difficulty 50.1±42.2, vitality 47.1±17.0, social function 74.8±18.5, pain 64.1±21.6, mental health 57.5±16.7 and general health perception 57.2±16.2. …”
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880
Flavones enrich rhizosphere Pseudomonas to enhance nitrogen utilization and secondary root growth in Populus
Published 2025-02-01“…Abstract Plant growth behavior is a function of genetic network architecture. The importance of root microbiome variation driving plant functional traits is increasingly recognized, but the genetic mechanisms governing this variation are less studied. …”
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