YAP1 activates SLC2A1 transcription and augments the malignant behavior of colorectal cancer cells by activating the Wnt/β-catenin signaling pathway by Kunpeng Li, Ya-Jie Dai, Haifeng Zhang, Zhigang Zhang

“…Methods GEO datasets (GSE14297, GSE18462, GSE40367) were analyzed to identify genes linked to metastasis in CRC, and TCGA-COAD system was used to analyze the expression pattern and prognostic values of SLC2A1 in CRC. Functional studies were conducted using CRC cell lines (Caco-2 and SW480). …”
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Long-Term Multimodal Exercise Intervention for Patients with Frontotemporal Lobar Degeneration: Feasibility and Preliminary Outcomes by Miyuki Nemoto, Kiyotaka Nemoto, Hiroyuki Sasai, Shinji Higashi, Miho Ota, Tetsuaki Arai

“…Cognitive, psychological, physical, and behavioral function tests were conducted before and after the intervention. …”
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Bonding Heterogeneity and Nanoprecipitation on Substituting the Anionic Framework in Mg3Sb2 for p‐Type Zintl Thermoelectrics by Nagendra Singh Chauhan, Takao Mori

“…The study highlights bonding heterogeneity‐induced structural transitions as an inherent challenge, where the dominant role of anionic sites becomes pivotal for determining/deriving favorable structural and functional properties in Mg3(Sb, Bi)2‐based zintl compounds.…”
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The Structural Simplification Hypothesis and the Premodifiers in Nigerian English by Mayowa Akinlotan

“…This paper conducts a corpus-based study of the occurrence/non-occurrence, structural pattern, and forms of the premodifier in the Nigerian English noun phrase, comparing the scenarios that emerge with those of the British and Ghanaian varieties of English. …”
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Restrictive Cardiomyopathies: The Importance of Noninvasive Cardiac Imaging Modalities in Diagnosis and Treatment—A Systematic Review by Aidonis Rammos, Vasileios Meladinis, Georgios Vovas, Dimitrios Patsouras

“…Echocardiography reveals normal or hypertrophied ventricles, preserved systolic function, marked biatrial enlargement, and impaired diastolic function, often with restrictive filling pattern. …”
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Exploring the c.406 C > T variant in TNNI3 gene: pathogenic insights into restrictive cardiomyopathy by Tannaz Masoumi, Hamed Hesami, Majid Maleki, Samira Kalayinia

“…In silico tools and structural protein modeling were employed to assess the functional impact of the identified variant. Results The c.406 C > T variant, classified as likely pathogenic, results in a truncated TNNI3 protein. …”
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Production capacity prediction of U-shaped horizontal wells for in-situ pyrolysis of tar-rich coal: Experimental and numerical simulation study by Zhen DONG, Yanpeng CHEN, Mengyuan ZHANG, Xinggang WANG, Lixin JIAO, Shuo FENG, Bo REN, Hao CHEN, Junjie XUE, Yufeng ZHAO, Diefang HUANG

“…CH4 and CO2 increase first and then decrease with temperature, the effect of confining pressure on the two sets of coal is different, and the application of confining pressure is more beneficial to coal gas production of Badaowan Formation coal. ③ Tar-rich coal pyrolysis product yield shows an S-shaped variation pattern of “slow increase - rapid increase - tends to stabilize” with increasing temperature, the Boltsmann function can better fit the law of tar-rich coal pyrolysis product yield. …”
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Alterations of static and dynamic changes in intrinsic brain activity and its relation to behavioral outcomes in subcortical ischemic stroke after one-month intervention by Yongxin Li, Jianping Wang, Maohua Yao, Yun Ran

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Urban structures and substructures by Mierzejewska Lidia

“…It will also propose an empirical research pattern. The term ‘substructures’ is taken to denote relatively autonomous, highly uniform wholes standing out in the spatial-functional structure of a town, distinguished on the basis of spatial relations generated by people. …”
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Dynamical modeling and experimental research on capillary flow of gallium-based liquid metal for reconfigurable structures by Chuanyang Jiang, Xiangpeng Li, Kaixuan Guo, Sheng Yang, Jiao Yu, Lu Cao, Wenchang Tan, Faxin Li

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Thermal characteristics of hybrid Nanofluid (Cu-Al2O3) flow through Darcy porous medium with chemical effects via numerical successive over relaxation technique by Assmaa Abd-Elmonem, Qammar Rubbab, Hakim AL. Garalleh, Fazeelat Rehman, Muhammad Amjad, Fayza Abdel Aziz ElSeabee, Nesreen Sirelkhtam Elmki Abdalla, Wasim Jamshed, Syed M. Hussain, Hijaz Ahmad

“…The present work offers insightful information on how the hybrid nanofluids behave and function in porous medium. The study's conclusions may have an impact on a lot of different engineering applications like filtration systems, chemical reactors, and environmental engineering. …”
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Nocturnal playback experiments: The response of two European species of birds to singing of foreign male at night. by Kinga Buda, Jakub Buda, Michał Budka

“…Recent studies have shown that nocturnal singing in diurnal birds is a common phenomenon, however, the understanding of the mechanisms, functions and consequences of this behaviour has been lacking. …”
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THE CLINICAL AND PATHOGENETIC FEATURES OF OSTEOARTHROSIS IN WOMEN WITH DIFFERENT TYPES OF OBESITY by Darya Andreyevna Kopylova, V A Ostapenko

“…Anthropometric characteristics, the duration of the disease, the degree of functional failure, and the levels of adipocytokines (adiponectin, interleukins (IL)-4 and -6) were estimated and X-ray study of the joints conducted. …”
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Modulatory effect of levodopa on the basal ganglia-cerebellum connectivity in Parkinson’s disease by Juyoung Jenna Yun, Subati Abulikemu, Kodchakorn Love Jangwanich, Yen F. Tai, Shlomi Haar

“…Using data from Parkinson’s Progression Marker Initiative, we investigated levodopa’s impact on resting-state functional connectivity within the cortico-basal ganglia-cerebellum system in 29 patients, under drug-naïve and levodopa-medicated conditions. …”
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Transcriptome and Endogenous Hormones Reveal the Regulatory Mechanism of Flower Development in <i>Camellia azalea</i> by Jian Xu, Fan Yang, Ruimin Nie, Wanyue Zhao, Fang Geng, Longqing Chen

“…These DEGs were further analyzed for functional enrichment using the GO and KEGG databases. …”
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Cloning and expression profile of an ubiquitin-conjugating enzyme-like gene OsCROC-1A in rice (Oryza sativa L.) by WANG Ya, LIU Jianping, XU Mengyun, JI Weijie, TU Jumin, ZHANG Xiaobo

“…Real-time quantitative PCR was conducted to analyze the spatial expression pattern of OsCROC-1A as well as the changes of its expression level under abiotic stresses. …”
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Oat and Forage Pea Mixed Sowing Improves Soil Chemical Fertility and Fresh and Dry Mass Yield in Light Saline–Alkali Land: Preliminary Results by Changying Guo, Chengti Xu, Xiaojian Pu, Yuanyuan Zhao, Jie Wang, Yunjie Fu, Wei Wang

“…Therefore, the 25 cm intercropping model not only optimizes hay yield, but also improves soil quality and ecological functions in saline–alkali land, offering valuable insights and practical recommendations for the sustainable use of saline–alkali land in the Qaidam Basin.…”
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Multizonal outer retinopathy and retinal pigment epitheliopathy (MORR) with a chronologically divergent presentation- a case report by Blerta Lang, Karl Boden, Boris V. Stanzel, Ulrich Prothmann, Peter Szurman

“…While initial stages may exhibit only subtle funduscopic changes, structural and functional deficits can progress rapidly, episodically and in a phase-shifted manner. …”
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Interleukin Family-Based Signature Relates to Cancer-Associated Fibroblasts Spatial Distribution and Immune Therapy Response in Pancreatic Carcinoma by Cheng Y, Xiao S, Li X, Wang B, Lei Y, Sun P, Ma L, Zhu Y

“…IL high-risk group also exhibited increased apCAF/tumor cell and apCAF/Tregs engagement, resulting in suppressed immune responses, crippled T-cell function and B-cell function, and elevated levels of biomarkers associated with poor immune response.Conclusion: This study constructed the first IL expression pattern related to CAFs infiltration, immunotherapy response, and prognosis in PC patients. …”
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Microvascular heterogeneity exploration in core and invasive zones of orthotopic rat glioblastoma via ultrasound localization microscopy by Xing Hu, Gaobo Zhang, Yong Wang, Xiandi Zhang, Rong Xie, Xin Liu, Hong Ding

“…Capillary pattern, capillary hemodynamics, and functional quantitative parameters were compared among tumor core, invasive zone, and normal brain tissue with ex vivo micro-computed tomography (micro-CT) and scanning electron microscopy. …”
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