Assessing individual head and neck squamous cell carcinoma patient response to therapy through integration of functional and genomic data by Daniel Bottomly, Chase Mathieson, Myles Vigoda, Sophia Jeng, Nathaniel Evans, Ashley Anderson, Aurora Blucher, Aletha Lesch, Christina Zheng, Ted Laderas, James Jacobs, Molly Kulesz-Martin, Shannon McWeeney

“…In addition to generating these deeply characterized functional genomics datasets, we also developed additional visual analytics that have the potential to provide greater insight into HNSCC drug response patterns and potentially aid precision oncology tumor boards in evaluation and assessment of effective targeted therapeutic agents.…”
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Finite Element Analysis of Functionally Graded Mindlin–Reissner Plates for Aircraft Tapered and Interpolated Wing Defluxion and Modal Analysis by Ali Hajjia, Mohammed Berrada Gouzi, Bilal Harras, Ahmed El Khalfi, Sorin Vlase, Maria Luminita

“…This theory works well for thicker structures, like aircraft wings, where it gives accuracy by detecting shear and rotation effects. FGMs, or functionally graded materials, are used in aviation to enhance structural patterns and reduce stress points by gradually changing material properties along the wing thickness based on the volume fraction index. …”
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<i>In Vitro</i> Assessment of Biological and Functional Properties of Potential Probiotic Strains Isolated from Commercial and Dairy Sources by Elmira Kelidkazeran, Meriam Bouri Yildiz, Fikrettin Sahin

“…This study provides valuable insights into the functional diversity of probiotics, suggesting their broader applications in health and nutrition. …”
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Radiation therapy induced intestinal barrier damage and repair process - differences in salivary metabolites and monitoring of intestinal barrier function by Zhang Jingjing, Wang Kun, Qiao Yanyu, Zhang Mengjie, Chen Yunqing, Tian Yulong, Jiao Xuelong, Tan Xiaojie, Jiang Haitao, Hou Feng

“…This study was conducted to investigate the changes, repair patterns, and potential mechanisms in patients after radiotherapy.MethodsThis study detected inflammatory factors in postoperative intestinal mucosal tissue and serum, as well as metabolites in saliva samples, and collected hematoxylin-eosin (HE)-stained pathological images in CRC patients who had received and did not receive radiotherapy.ResultsThe results showed that after radiotherapy, there were significantly impaired intestinal mucosal tissue structure; obviously elevated inflammatory factors in intestinal mucosal tissue and blood; as well as upregulation/downregulation of metabolites in saliva samples.ConclusionIn conclusion, findings in this study may provide potential reference for predicting the recovery of intestinal mucosa and selecting the optimal timing for surgery after radiotherapy. …”
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Wisdom of the Established Pattern by Joel Janhonen

“…Enduring Wisdom We can contend with this uncertainty over present adaptive value by either relying on the established patterns of judgment-formation before maladaptiveness is demonstrated or by insisting on fully rational conduct without any mental shortcuts or filtering of information. …”
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Similar alpha yet varied beta functional diversities between invasive and native plant species along an elevational gradient by Yan-Yan Wang, Kun Guo, Rui-Ling Liu, Hasigerili, Miao-Miao Zheng, Yuan Gao, Ming-Shui Zhao, Jian Zhang, Wen-Yong Guo

“…Our results revealed significant distinctions in diversity patterns between invasive and native species when considering multiple aspects of taxonomic and functional diversity at both α and β levels. …”
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Respiratory Function and Information Processing Speed in Coal Power Plant Workers: Moderating Effects of Physical Activity and Sedentary Behavior by Kim PS, Lai TF, Park JH, Jang M, Shin YK, Kim DR, Wang IJ, Choi HJ, Lee JI

“…Multiple linear regression analyses were performed to examine the associations between respiratory function and cognitive performance, stratified by physical activity levels and sedentary behavior patterns.Results: After adjusting for covariates, in the active group (≥ 150 min/week of moderate-to-vigorous physical activity), individuals with MIP < 80% showed significantly lower information processing speed scores (B = − 6.341, 95% CI: − 11.709 to − 0.972, p = 0.021) compared to those with MIP ≥ 80%. …”
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Purinergic receptor antagonism reduces interictal discharges and rescues cognitive function in a mouse model of temporal lobe epilepsy by Nelson Espinosa, Soraya Martín-Suárez, Ariel Lara-Vasquez, Trinidad Montero, Teresa Muro-García, German Fernandez, Juan Manuel Encinas-Pérez, Juan Manuel Encinas-Pérez, Juan Manuel Encinas-Pérez, Pablo Fuentealba

“…We used TNP-ATP, a potent purinergic receptor antagonist, and conducted experiments using a mouse model of mesial temporal lobe epilepsy to examine behavioral performance and neural activity patterns. …”
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Interpretations of Pre-service Elementary Mathematics Teachers on the Functions of Non-Textual Elements: Case Study on Algebra Learning Area by Murat Genç, Mustafa Akıncı

“…Data were collected from thirty-one undergraduate students through a task-based written questionnaire including seven non-textual elements on the algebra learning domain. Data analysis was conducted using a content analysis approach to generate themes and uncover previously unspecified patterns. …”
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Cloning, phylogenetic analysis, tissue expression profiling, and functional roles of NPC1L1 in chickens, quails, and ducks by Xin Shu, Ziwei Chen, Hui Wang, Bingjie Xu, Li Liu, Jilong Zhang, Xiaotong Zheng, Jianfei Chen

“…Further experiments are required to elucidate the biological function of poultry NPC1L1. In summary, this study successfully cloned the full-length sequence of NPC1L1 from chickens, quails, and ducks, and conducted a comprehensive analysis of their evolutionary history and expression patterns. …”
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The integrative genomic and functional immunological analyses of colorectal cancer initiating cells to modulate stemness properties and the susceptibility to immune responses by Issam Tout, Salim Bougarn, Mohammed Toufiq, Neha Gopinath, Ola Hussein, Abbirami Sathappan, Evonne Chin-Smith, Fazulur Rehaman, Rebecca Mathew, Lisa Mathew, Kun Wang, Li Liu, Abdulrahman Salhab, Oleksandr Soloviov, Sara Tomei, Waseem Hasan, Sahar Da’as, Yosra Bejaoui, Nady El Hajj, Karama Makni Maalej, Said Dermime, Kakil Rasul, Paolo Dellabona, Giulia Casorati, Alice Turdo, Matilde Todaro, Giorgio Stassi, Soldano Ferrone, Xinhui Wang, Cristina Maccalli

“…Functional immunological assays were performed to assess the impact of miRNA modulation. …”
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Functions of Smartphone Apps and Wearable Devices Promoting Physical Activity: Six-Month Longitudinal Study on Japanese-Speaking Adults by Naoki Konishi, Takeyuki Oba, Keisuke Takano, Kentaro Katahira, Kenta Kimura

“…The secondary objective was to explore which functions and features of PA apps predict changes in PA levels. …”
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Effects of He irradiation on the microstructure and thermal conductivity of SiC by Wantong Sun, Shouxi Gu, Baolong Ji, Qiang Qi, Hai-Shan Zhou, Guang-Nan Luo

“…SiC is considered as a structural and functional material in fusion reactors due to its exceptional radiation resistance, chemical inertness, and low neutron absorption cross-section. …”
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Functional traits as indicators of maize (Zea mays L.) strategies to cope with Zn, Pb and Cr heavy metal-induced stress by Lina Fusaro, Francesca Lanni, Laura Varone, Giuseppina Falasca, Silvia Serranti, Riccardo Gasbarrone, Davide Gattabria, Vincenza Cozzolino, Alessandro Piccolo, Fausto Manes

“…Results revealed distinct response patterns: tolerance to Zn, without adverse effects on photosynthetic traits; resistance to Pb, mediated by increased RD and photoprotection through change in reflectance indices; and sensitivity to Cr highlighted by severe functional impairments of all the studied photosynthetic traits and structural root damages. …”
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Association between pan-immune-inflammation value and Serum Klotho levels: a cross-sectional analysis of renal function mediation by Mingjie Liu, Xuan Zhou, Han Xu, Yan Wang, Yuting Duan, Xiangru Guo, Bai Wei

“…Mediation analysis was conducted to assess the role of renal function indicators. …”
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Correlation between Electrochemical Relaxations and Morphologies of Conducting Polymer Dendrites by Antoine Baron, Enrique H. Balaguera, Sébastien Pecqueur

“…Conducting Polymer Dendrites (CPD) can engrave sophisticated patterns of electrical interconnects in their morphology with low-voltage spikes and few resources: they may unlock in operando manufacturing functionalities for electronics using metamorphism conjointly with electron transport as part of the information processing. …”
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Incident arrhythmias in relation to ventilatory parameters and pulmonary disease: evidence from two prospective cohort studies by Yun-Jiu Cheng, Li-Ping Qu, Yi-Jian Liao, Si-Long Lu, Mei-Ping Lin, Qian He, Jin-Bo Fu, Jun-Chi Li, Wen-Juan Duan, Li-Juan Liu

“…Conclusions Reduced pulmonary function suggested independent associations with incident arrhythmias across supraventricular, ventricular, and conduction system pathologies in two historical cohorts. …”
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How Does the Scale and Functional Diversity of the Innovation Cooperation Network Affect Local Innovation? Township-Level Evidence from Beijing by Jingxin Nie, Tiantian Li, Tianming Zheng

“…The results show that the township-level scale and functional diversity of the ICN in Beijing have increased by over 40%, accompanied by a transformation in the core–periphery distribution pattern. …”
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Empirical evidence for the functional benefit of intra-specific wing shape variation in a sedentary bird, the Oriental Magpie (Pica serica) by Seokbong Chae, Jusun Hwang, Jae Chun Choe, Piotr G. Jablonski, Sang-im Lee, Jooha Kim

“…In order to examine the functional aspect of this pattern of variation, we conducted wind tunnel experiments and measured the aerodynamic performances of three wings by varying the position of wingtip from forward to backward. …”
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The association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and pulmonary function: evidence from NHANES 2007–2012 by Miaoyan Liu, Chaofeng Gao, Jinggeng Li, Yibo Zhang, Rui Gao, Chaoting Yang, Jian Zhang

“…However, the correlation between FEV1/FVC and NHHR showed a nonlinear U-shaped pattern. Suggesting differential impacts of NHHR on various lung function indicators. …”
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