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1261
Effect of traditional Chinese medicine combined with conventional Western medicine for patients with severe/very severe chronic obstructive pulmonary disease: a multi-center, rando...
Published 2025-05-01“…This study aimed to evaluate the clinical efficacy of comprehensive therapy based on TCM patterns for patients with stable, severe to very severe COPD. …”
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1262
Identification of hub genes in myocardial infarction by bioinformatics and machine learning: insights into inflammation and immune regulation
Published 2025-06-01“…These genes were then subjected to functional enrichment analysis, including Kyoto Encyclopedia of Genes and Genomes (KEGG), Gene Ontology (GO), and Gene Set Enrichment Analysis (GSEA). …”
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1263
Circulating Plasma Proteins as Biomarkers for Immunotherapy Toxicity: Insights from Proteome-Wide Mendelian Randomization and Bioinformatics Analysis
Published 2025-07-01“…Circulating plasma proteins, dynamically accessible and functionally linked to immunity, may predict and offer novel targets for irAEs. …”
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1264
Exploration of biomarkers associated with histone lactylation modification in spinal cord injury
Published 2025-07-01“…Inter-cluster comparisons were conducted to examine Hallmark pathways, HLA genes, and immune functions. …”
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1265
Expressing the Author's Position in the English-Language Network Film Review
Published 2021-12-01“…The authors proceed from the position that the methods of subject verbalization are determined by functional characteristics of discourse. The relevance of the study is due to the interest of modern linguistics in the study of the subject factor in “personal” types of discourse. …”
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1266
Modeling Navigator Awareness of COLREGs Interpretation Using Probabilistic Curve Fitting
Published 2025-05-01“…This study models navigator awareness as a probabilistic function of encounter angle, aiming to identify interpretive transition zones and cognitive uncertainty in rule application. …”
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1267
A Temporal Convolutional Network–Bidirectional Long Short-Term Memory (TCN-BiLSTM) Prediction Model for Temporal Faults in Industrial Equipment
Published 2025-02-01“…The TCN layer incorporates batch normalization, an optimized activation function (Leaky ReLU), and a dropout mechanism to enhance its ability to capture multi-scale temporal features. …”
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1268
Effects of dihydroquercetin (DHQ “P” drops) in patients with previous transitory ischemic attacks associated with visual disorders
Published 2020-12-01“…Such positive effects in the conducted study were characterized as tendency pattern (OR 2.87; p=0.08 for perivascular edema and OR 2.77; p=0.08 for microhemorrhages). …”
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1269
Green tea dye ligands to transfer toxic lead metal ions to precipitated metal complexes for polymer composite applications
Published 2025-07-01“…The FTIR approach established that green tea dye (GTD) is enriched with ligands containing NH/OH, C = C, and C = O functional groups, which capture Pb2+ metal ions and form Pb-metal complexes. …”
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1270
Tropical infections and the gut microbiome: dysbiosis, recovery, and clinical implications
Published 2025-08-01“…A structured literature search was conducted across PubMed, Scopus, and Web of Science, focusing on human GI microbiome dynamics, dysbiosis patterns, and recovery mechanisms in the context of tropical infectious diseases. …”
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1271
Near-source wastewater surveillance of SARS-CoV-2, norovirus, influenza virus and RSV across five different sites in the UK.
Published 2025-01-01“…Sites were selected for contrasting functions: an office, charity centre, museum, university, and care home. …”
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1272
Experimental study on modal analysis and vibration response of tunnel structures under different damage conditions due to subway train loads
Published 2025-01-01“…Abstract Based on a prototype of the Beijing subway tunnel, this research conducts large-scale model experiments to systematically investigate the vibration response patterns of tunnels with different damage levels under the influence of measured train loads. …”
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1273
Life satisfaction in emerging adulthood: a longitudinal study of social support, resilience, and gender differences
Published 2025-07-01“…The gender-specific patterns observed in the findings underscore the relevance of developing mental health interventions that consider individual differences in support utilization and coping strategies. …”
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1274
Historical and sociological analysis of the development of the Russian society in transition as a social dissipative system in a bifurcation zone
Published 2023-02-01“…The author of the article studies the phenomenon of a dissipative system, the patterns of functioning and development of social dissipative systems as well as their behavior in the bifurcation zone. …”
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1275
Leveraging 'golden-hour' WUE for developing superior vegetable varieties with optimal water-saving and growth traits
Published 2024-01-01“…However, while reducing stomatal conductance can boost water use efficiency (WUE), it results in a decline in photosynthetic assimilation capacity, because stomata function as a shared conduit for both CO2 intake and water evaporation. …”
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1276
Enhancing mPFC to BLA information transmission through chemical genetics to improve exploratory behavior in chronic stress rats
Published 2025-06-01“…Through simultaneous monitoring of behavioral patterns and local field potentials (LFPs) in both mPFC and BLA during open-field exploration, we conducted comparative analyses between chemogenetically activated and sham-stimulated groups. …”
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1277
Dynamic development of gut microbiota and metabolism during and after weaning of kittens
Published 2025-01-01“…However, the specific changes in gut microbiota and metabolites in kittens following weaning remain unclear. In this study, we conducted a comprehensive investigation of the dynamic changes in the gut microbiota, serum metabolism, antioxidant capacity, and immune function of kittens at various time points: days 0, 4, and 30 post-weaning. …”
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1278
Bioinformatic Insights and XGBoost Identify Shared Genetics in Chronic Obstructive Pulmonary Disease and Type 2 Diabetes
Published 2025-03-01“…A multifaceted bioinformatics approach, encompassing the limma R package, unified matrix analysis, and weighted gene co‐expression network analysis (WGCNA), was deployed to identify differentially expressed genes (DEGs) and hub genes. Functional enrichment and protein–protein interaction (PPI) analyses were conducted, followed by cross‐species validation in Mus musculus models. …”
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1279
<i>Mycobacterium Ulcerans</i> Ulcer: Current Trends in Antimicrobial Management and Reconstructive Surgical Strategies
Published 2025-07-01“…Its toxin, mycolactone, drives tissue destruction, and the infection is transmitted via environmental reservoirs or vectors. Disease patterns vary globally, and an improved understanding of their pathogenesis may enhance current antimicrobial and surgical treatments. …”
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1280
Identification and Characterization of the OCT4 Upstream Regulatory Region in Sus scrofa
Published 2019-01-01“…However, the OCT4 promoter and four regulatory regions, including distal and proximal enhancer elements, had high similarity. Next, a functional analysis of the porcine OCT4 promoter region was conducted. …”
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