IN SEARCH OF ONE’S OWN IDENTITY: ANGELA CARTER’S SHORT STORY COLLECTION FIREWORKS by Nadiya Yu. Polishchuk

“…The paper aims to explore the mechanisms of functioning the characters’ identity, in particular, two distinct processes of its representation within the prose collection: a) the creation and b) the destruction. …”
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21st Century Televisuality? Golden Ages and Collateral Damage in Industry Stress Research by John T. Caldwell

“…Triggered disclosures of this sort may offer a more convincing way to understand the televisual complexities—and system-wide functions—of golden-age digital innovations.…”
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The role of SH3RF2 in lung squamous cell carcinoma and M2 polarization: insights into LZTS2 ubiquitination by Jie Yang, Zhongfei Jia, Juan Li, Chao Jiang, Xin Zhao, Yuxiang Wang, Xiaoguo Ma, Xinjian Xu

“…Conclusions This study demonstrates the functionality of SH3RF2 in both potentiating tumor progression and inducing M2 macrophage polarization through coordinated regulation of LZTS2 degradation and β-catenin nuclear translocation. …”
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Cyanoexosortase B is essential for motility, biofilm formation, and scytonemin production in a filamentous cyanobacterium by Gabriel A. Parrett, Daniel H. Haft, Maida Ruiz, Ferran Garcia-Pichel, Christopher C. Ebmeier, Douglas D. Risser

“…Here, we characterize the role of cyanoexosortase B (CrtB) in the filamentous cyanobacterium Nostoc punctiforme, demonstrating that crtB is essential for motility, biofilm formation, and the production of the sunscreen pigment scytonemin. …”
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Combining gene expression microarrays and Mendelian randomization: exploring key immune-related genes in multiple sclerosis by Shuangfeng Ding, Yunyun Zhang, Yunzhe Tang, Ying Zhang, Mingyuan Liu

“…GO and KEGG analyses were subsequently performed to elucidate the functions and pathways associated with the IM-DEGs. …”
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Role of Interleukins in Type 1 and Type 2 Diabetes by Roha Asif, Ammara Khalid, Tolga Mercantepe, Aleksandra Klisic, Sana Rafaqat, Saira Rafaqat, Filiz Mercantepe

“…<b>Objective</b>: This narrative review aims to provide a comprehensive and critical synthesis of current evidence on the role of key interleukins in T1D and T2D, highlighting their immunological functions, genetic associations, clinical correlations, and translational potential. …”
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Metamodels of Educational and Methodological Activity in the University by S. M. Shcherbakov, K. K. Kalugyan, I. I. Miroshnichenko

“…Such concepts as “competence”, “type of activity”, “tasks of professional activity”, “labor functions”, etc. appear and then transform. The present work aims to track the dynamics of these changes and assess the increase in the complexity of educational methodological support. …”
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Identification and Validation of Feature Genes Related to Mitochondrial Dysfunction and Oxidative Stress in Ulcerative Colitis by Wu Y, Tan Z, Lan Q, Liu Y, Liu C, He H, Zhang J, Dong W

“…Given their close association, it is crucial to clarify the molecular characteristics and biological functions of MD and OS-related genes in UC.Methods: Gene expression profiles, mitochondrial-related genes, and OS-related genes were obtained from the corresponding databases. …”
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Methodology and methods of training children with disabilities in an inclusive distance education system by T. M. Egorova, N. N. Belukhina, T. S. Akhmedzyanova

“…In the future, a set of conditions for the functioning and development of an inclusive regional distance education system for children with disabilities will be identified, causing the learning process in the system under study. …”
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Antibiofilm properties of 4-hydroxy-3-methyl-2-alkenylquinoline, a novel Burkholderia-derived alkaloid by McKinley D. Williams, Taylor R. Sweeney, Sabrina Trieu, Ravi Orugunty, Abdelahhad Barbour, Fereshteh Younesi, Michael Glogauer, Nopakorn Hansanant, Ronald Shin, Shi-En Lu, Kevin Cao, Abraham Tenorio, Sigmund J. Haidacher, Anthony M. Haag, Thomas D. Horvath, Leif Smith

“…The antibiofilm properties of the HMAQ-7′ characterized in this study will promote future investigations into possible biological and applied roles. …”
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C-type lectin (SpCTL) through its binding to Spβ-integrin regulates antimicrobial peptide synthesis in mud crab (Scylla paramamosain) during Vibrio parahaemolyticus infection by Wei Yang, Yuyong He, Huifen Liang, Junyuan Lin, Ngoc Tuan Tran, Zhinuo Du, Ming Zhang, Ruhan Chen, Yuqing Zheng, Xu Meng, Shengkang Li

“…In this study, the mud crab SpCTL cDNA was cloned and functionally characterized. Phylogenetic analysis showed that SpCTL was closely related to Eriocheir sinensis with 81 % homology. …”
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Multidimensional transcriptomics based to illuminate the mechanisms of taurine metabolism in immune resistance of pancreatic cancer by Zongshuai Qin, Zongshuai Qin, Guixiang Huang, Guixiang Huang, Jian Xu, Jian Xu, Lujuan Pan, Chaojun Lan, Chaojun Lan, Yuhuan Yang, Yuhuan Yang, Yixia Yin, Yueqiu Qin, Yueqiu Qin, Yueqiu Qin

“…Pancreatic cancer, a highly malignant tumor of the digestive system, is characterized by a tumor microenvironment with a high degree of immunosuppression. …”
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3D graphene paper-based tandem metal-free thin-film supercapacitors with integrated 200 V output by Huilong Liu, Litian Gan, Renji Chen, Zhiwen Xiao, Yun Chen, Hongzuo Yang, Yahang Liu, Baisheng Wu, Ching-Ping Wong, Xin Chen

“…The active area of electrodes is defined by a PI mask, with the help of which a hydrogel electrolyte functions as a separator. The assembled graphene paper-based TFSCs demonstrate outstanding electrochemical performance and mechanical flexibility, with the areal capacitance of 54.5 mF·cm ^−2 , energy density of 10.9 μWh·cm ^−2 , and cycle stability retention of 86.9% over 15 000 cycles. …”
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Interleukin-21 engineering enhances CD19-specific CAR-NK cell activity against B-cell lymphoma via enriched metabolic pathways by Bailin He, Hong Chen, Jiaxu Wu, Shiqiu Qiu, Qiusui Mai, Qing Zeng, Cong Wang, Shikai Deng, Zihong Cai, Xiaoli Liu, Li Xuan, Chengyao Li, Hongsheng Zhou, Qifa Liu, Na Xu

“…The phenotypic profile, transcriptomic characteristics, functionality and anti-tumor activity of CAR-21 NK cells and CAR-15 NK cells were compared. …”
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Hard rock aquifer architecture and water circulation levels in the Strengbach critical zone observatory (France) by Chabaux, François, Négrel, Philippe, Gal, Frederick, Viville, Daniel, Ranchoux, Coralie, Van der Woerd, Jérome, Delay, Frederick, Ackerer, Julien, Aquilina, Luc, Diraison, Marc, Masson, Frédéric, Mériaux, Anne-Sophie, Labasque, Thierry, Lucas, Yann, Pezard, Philippe Adrien, Reuschlé, Thierry, Schmitt, Anne-Désirée, Stille, Peter, Wyns, Robert, Lerouge, Catherine, Dezayes, Chrystel

“…These results from the Strengbach CZ demonstrate the importance of integrating geological history of the watershed, either the long-term geological bedrock evolution or the Quaternary erosion patterns, to better understand and model the CZ hydrological functioning at the watershed scale.…”
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Oncolytic VSV-IL-2 has enhanced anticancer vaccination adjuvant abilities by Marie-Claude Bourgeois-Daigneault, Victor Mullins-Dansereau, Marie-Lou Myre, Angelina Bardoul, Karen Geoffroy, Marco J Rallo Pita, Delphine Béland, Kim Leclerc Desaulniers, Dominic Guy Roy

“…The immune response induced by each vaccination regimen was assessed by flow cytometry to characterize antigen-specific CD8 T cells over time. …”
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Validation of a comprehensive long-read sequencing platform for broad clinical genetic diagnosis by Siddhartha Sen, Hillary P. Handler, Alec Victorsen, Zach Flaten, Aidan Ellison, Todd P. Knutson, Sarah A. Munro, Ryan J. Martinez, Charles John Billington, Jennifer J. Laffin, Sarah Bray, Pawel Mroz, Sophia Yohe, Andrew C. Nelson, Matthew Bower, Bharat Thyagarajan

“…Our findings suggest that long-read sequencing is successful in identifying diverse genomic alterations and that our pipeline functions well as the basis for a single diagnostic test for patients with suspected genetic disease.…”
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Main circulating CD8⁺ T cell subsets in patients with systemic lupus erythematosus by S. S. Benevolenskaya, I. V. Kudriavtsev, M. K. Serebriakova, A. A. Rubinstein, E. S. Kuvardin, I. N. Grigor’yeva, D. B. Aliev, D. B. Zammoeva, D. B. Motorin, A. S. Golovkin, O. V. Kalinina, S. V. Lapin, I. Z. Gaydukova, A. L. Maslyanskiy, E. K. Gaydukova

“…While Tc1, Tc17, Tc17.1, Tfc subsets probably have regulatory functions…”
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Comprehensive Analysis of the Complete Mitochondrial Genome of <i>Paeonia ludlowii</i> Reveals a Dual-Circular Structure and Extensive Inter-Organellar Gene Transfer by Zhefei Zeng, Zhengyan Zhang, Ngawang Norbu, Ngawang Bonjor, Xin Tan, Shutong Zhang, Norzin Tso, Junwei Wang, La Qiong

“…This multipartite genome structure is characterized by abundant repetitive elements (112 functionally annotated SSRs, 33 tandem repeats, and 945 dispersed repeats), which potentially drive genome rearrangements and facilitate adaptive evolution. …”
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C5aR1 blockade reshapes immunosuppressive tumor microenvironment and synergizes with immune checkpoint blockade therapy in high-grade serous ovarian cancer by Chen Zhang, Kankan Cao, Moran Yang, Yiying Wang, Mengdi He, Jiaqi Lu, Yan Huang, Guodong Zhang, Haiou Liu

“…C5aR1 expression independently predicted dismal prognosis and was linked to the immunoevasive subtype of HGSC, characterized by increased infiltration of pro-tumor cells (Treg cells, M2-polarized macrophages, and neutrophils) and impaired CD8+T functions. …”
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