Enhanced breast cancer cell targeting: RGD integrin ligand potentiates RWQWRWQWR’s cytotoxicity and inhibits migration by Andrea Barragán-Cárdenas, Daniel Castellar-Almonacid, Yerly Vargas-Casanova, Claudia Parra-Giraldo, Adriana Umaña-Pérez, Joel López-Meza, Zuly Rivera-Monroy, Javier García-Castañeda

“…Aim: Evaluate the selective cytotoxic effect of the palindromic sequence RWQWRWQWR and its analogues obtained by replacement of L-amino acids by D-amino acids or the functionalization by adding the RGD (integrin ligand motif) to the peptide. …”
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Membrane Permeability Monitoring to Antipsychotic Olanzapine Using Platinum Black-Modified Electrodes by Murugaiya Sridar Ilango, Dayananda Desagani, Srikanth Jagadeesan, Alexander Snezhko, Gad Vatine, Hadar Ben-Yoav

“…The blood–brain barrier (BBB) is key to the regular functioning of the central nervous system. The dysfunction of the BBB has been described in various neurological disorders, including schizophrenia. …”
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Clock Proteins Have the Potential to Improve Term Delivery Date Prediction: A Proof-of-Concept Study by Max T. Dufford, Tracey C. Fleischer, Laura J. Sommerville, Md. Bahadur Badsha, Ashoka D. Polpitiya, Jennifer Logan, Angela C. Fox, Sharon R. Rust, Charles B. Cox, Thomas J. Garite, J. Jay Boniface, Paul E. Kearney

“…A total of 15 proteins of diverse functionalities were shown to have a direct association with time to birth (TTB), 11 of which have not been previously linked to gestational age. …”
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Genomically-selected antifungal Bacillaceae strains improve wheat yield and baking quality by Alejo Casal, Fernán Oscar Gizzi, Sol Agostina Figueroa, Tomás Denis Petitti, Facundo Ferragutti, Jimena Gaido, Mariano Alberto Torres Manno, Gabriel Céccoli, Luciana Paoletti, Christopher Dunlap, Lucas Damián Daurelio, Martín Espariz

“…This study employed genomic and phenotypic approaches to characterize wheat rhizosphere-associated Bacillaceae for agricultural applications. …”
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Gender differences in eating disorders by Elena Ilaria Capuano, Angela Ruocco, Beatrice Scazzocchio, Giulia Zanchi, Camilla Lombardo, Annalisa Silenzi, Elena Ortona, Rosaria Varì

“…Eating disorders (EDs) are characterized by disturbances in eating behavior and occur worldwide, with a lifetime prevalence of 2 to 5%. …”
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Soil microplastic pollution in China: Current insights and future perspective by ZHANG Yan, DOU Ming, HAO Songze, LI Ping, WANG Guohao, ZHOU Yuze, LIANG Zhijie

“…While their presence and impacts in other ecosystems have been well documented, their occurrence in soils and potential implications for environmental and ecological functions, as well as food security, remain poorly understood. …”
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The role of galectin-1 and galectin-3 in the mechanisms of T-cell immune response dysregulation in colon cancer by V. S. Poletika, Yu. V. Kolobovnikova, O. I. Urazova, O. A. Vasileva, A. I. Dmitrieva, K. I. Yankovich, V. V. Novitsky, L. M. Ryabova, M. Yu. Grishchenko

“…In colon cancer, increased levels of galectin-1 and galectin-3 in the blood are associated with quantitative deficiency and inhibited secretory activity of effector T lymphocytes and activation of the immunosuppressive functions of regulatory T cells. These results suggest a negative role of galectin 1 and galectin 3 in the mechanisms of regulation of the T cell immune response in colon cancer.…”
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Human papillomavirus E1 proteins inhibit RIG-I/MDA5-MAVS, TLR3-TRIF, cGAS-STING, and JAK-STAT signaling pathways to evade innate antiviral immunity by Jin-Xin Li, Jing Zhang, Cheng-Hao Li, Yun-Fang Li, Hui-Min Chen, Tao Li, Qing Zhang, Qing Zhang, Bei-Hua Kong, Bei-Hua Kong, Pei-Hui Wang, Pei-Hui Wang

“…While viral proteins such as E6 and E7 are well-established regulators of immune evasion, the role of E1 in modulating the host antiviral responses remains insufficiently characterized. This study investigates the immunomodulatory functions of HPV16 and HPV11 E1 in suppressing innate antiviral immune signaling pathways. …”
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Composition of the culturable bacterial community associated with the water column and soft tissues from oysters of the mangrove ecosystem at Honda Swamp, Colombian Caribbean by Lersy López Gutiérrez, Martha Torres, Esteban Zarza González, Alejandro Henao Castro, Laura Contreras Vega

“…Microbiological activity is the basis of ecosystems functioning, among these are the mangroves, which offer a wide variety of goods and services to humanity. …”
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Annual cycle variations in the gut microbiota of migratory black-necked cranes by Yujia Zhang, Ruifeng Ma, Suolangduoerji, Shujuan Ma, Shujuan Ma, Akebota Nuertai, Ke He, Hongyi Liu, Ying Zhu

“…And the summer samples exhibited higher alpha (Simpson and Shannon), beta diversity (Bray-Curtis and UniFrac) and more diverse functions in gut microbiota compared to other seasons. …”
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Unfolding boron dynamics at the scale of soil-water-fertilizer-crop systems in the tropics: from soil availability to plant requirements by Cassio Hamilton Abreu-Junior, Juan Ricardo Rocha, Timóteo Herculino da Silva Barros, Gabriele Rossini Moreira, Vinícius Pires Rezende, Viviane Nunes dos Santos Cagliari, Carlos da Rocha Junior, Alyam Dias Coelho, Rodrigo Marcelli Boaretto, Gian Franco Capra, Thiago Assis Rodrigues Nogueira, Arun Dilipkumar Jani, José Lavres Júnior

“…This review aims to understand B dynamics in tropical soils, its functions in higher plants cultivated in these regions, and how its deficiency and/or toxicity can affect agricultural production.…”
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Impact of nanoparticles shapes and fuzzy volume fraction on Al2O3 – H2O nanofluid flow past an unsteady expandable surface by Adnan Saeed Butt, Naveed Yaqoob, Sameea Akbar, Gul M. Shaikh, Adeeba Farhat, Fouzia Amir, Mohamed R. Ali

“…This study compares cylinder and brick-shaped nanofluids using membership functions (MFs), where the nanoparticle volume fraction is represented as a triangular fuzzy number (TFN), controlled by the α-cut, varying between 0 and 1. …”
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“Well, it’s very doctor-related” – interprofessional communication and collaboration between GP practices and nurses in the ambulant setting: a qualitative study in southern German... by Kim Nordmann, Stefanie Sauter, Marie-Christin Redlich, Patricia Möbius-Lerch, Michael Schaller, Florian Fischer

“…Conclusions Current interaction patterns are deficient and require political, structural and educational changes to establish well-functioning collaboration in the ambulant sector that facilitates patient-centred care. …”
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Investigation of buckling modes of sandwich specimens with facing layers from [0°]s fiber-reinforced plastic under axial compression by V.N. Paimushin, S.A. Kholmogorov, N.V. Polyakova, M.A. Shishov

“…The latter allow integration over the thickness with the introduction of two unknown functions (transverse tangential stresses). In the linearized equations used, the physical nonlinearity of the material of the facing layers was taken into account in accordance with the Shanley concept based on the introduction of the tangential transverse shear modulus. …”
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Genome Sequences of the First Phages Infecting <i>Limnohabitans</i> Reveal Their Global Distribution and Metabolic Potential by Boxuan Deng, Raoqiong Che, Pinxin Zhu, Yongxia Wang, Zhiying Li, Shiying Zhang, Wei Xiao

“…Bacteriophages (phages) are one of the critical biotic drivers of prokaryotic community dynamics, functions, and evolution. Despite their importance in aquatic ecosystems, very few phages have been isolated from freshwater lakes, hampering our understanding of their ecological importance and usage in a variety of biotechnological applications. …”
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Sustainability of small dams for livestock and farming, a case study from Chitongo dam, rural Zambia by Livia Serrao, Livia Serrao, Simone Caridi, Ali Farrokhi, Diego Avesani, Muyaka Kamamba, Mireille Galli, Chalwe Chibwe, Federica Medici, Sara Treccani, Joel Kabika, Kawawa Banda, Marco Bezzi, Massimo Zortea, Maybin Ng’ambi, Guido Zolezzi, Guido Zolezzi

“…Such a scalable approach can be adopted to support the development of regional programs for rural water security in drylands, which should engage local actors in water allocation and reservoir maintenance plans for ensuring its functioning and fair benefits distribution for a reasonable time span.…”
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Neuroprotective effects of repetitive transcranial magnetic stimulation on Alzheimer's disease: Undetermined therapeutic protocols and mechanisms by Yang Zhu, Lingyi Liao, Shihao Gao, Yong Tao, Hao Huang, Xiangqin Fang, Changyan Yuan, Changyue Gao

“…Abstract Alzheimer's disease (AD) is a prevalent neurodegenerative disorder characterized by gradual deterioration of cognitive functions, for which an effective treatment is currently unavailable. …”
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Electrochemical Sensing of Neurotransmitters Using a Metal Nanoparticle-Based Composite Platform by Stelian Lupu, Sorina-Alexandra Leau, Cecilia Lete, Ioana Diaconu, Cristian Matei

“…Neurotransmitters play important roles in the normal functioning of the central nervous system. The accurate and sensitive quantification of neurotransmitters using chromatographic and optical analytical methods is of key interest in the management of related neurodegenerative maladies. …”
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Current Perspectives on Anorexia Nervosa in Health and Therapy - a review by Wojciech Bieńkowski, Julia Charkot, bartlomiej kusy, Michał Bieńkowski, Mikołaj Charkot, Piotr Kucharczyk, Irmina Jaszczuk, Patrycja Retman

“… Introduction and purpose: Anorexia nervosa is a serious mental disorder characterized by persistent food restriction, intense fear of gaining weight, and distorted body image. …”
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Methylation assay in KMT2B-related dystonia: a novel diagnostic validation tool by Gleyson Francisco da Silva Carvalho, Claudio Melo de Gusmão, Beatriz Martins Wolff, Lucas Liro Vieira, Yanca Gasparini de Oliveira, Mariana Ribeiro Costa, Rafaela da Silva Mendes, Matheus Augusto Araujo Castro, Mayara T. Sakuma, Fernando Kok, Bekim Sadikovic, Leslie Domenici Kulikowski

“…In this study, we describe the use of a genome methylation episignature methodology to functionally validate two variants of uncertain significance (VUS) in the KMT2B gene. …”
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