Stabilization strategies and optimization of polyvinyl alcohol-chitosan hybrid polymer by Maitreyi Sawant, Triparna Chakraborty, Dharmveer Yadav, Santosh Biranje, Sumit Saxena, Shobha Shukla

“…NaOH treatment further strengthened the films due to hydroxide functionalization, improving intermolecular interactions. …”
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Molecular dynamics simulation of wild and mutant proteasome subunit beta type 8 (PSMB8) protein: Implications for restoration of inflammation in experimental autoimmune encephalomy... by Shamrat Kumar Paul, Md Saddam, Nisat Tabassum, Mahbub Hasan

“…Our study provides valuable insights into the dynamics and structure of this protein, which can aid in further understanding its biological functions and potential implications for disease.…”
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APJ regulates the balance between self-renewal and differentiation of vascular endothelial stem cells by Man Wang, Fitriana Nur Rahmawati, Wenting Li, Zeynep Bal, Faya Nuralda Sitompul, Fumitaka Muramatsu, Weizhen Jia, Nobuyuki Takakura

“…Methods APJ knockout (KO) mice were utilized to explore the role of apelin/APJ signaling in VESC functionality. Flow cytometry, colony-forming unit assays, and in vitro differentiation experiments were conducted to characterize VESC populations. …”
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TEMPO-Oxidized Spruce Galactoglucomannan–Biopolymer with Enhanced Antioxidant Activity and Selective Heavy-Metal Sorption by Vladislav A. Ionin, Yuriy N. Malyar, Valentina S. Borovkova, Dmitriy V. Zimonin, Aleksandr S. Kazachenko

“…Nevertheless, there are various ways to enhance its functionality via oxidative TEMPO/NaBr/NaOCl processing. …”
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<i>MECP2</i> mRNA Profile in Brain Tissues from a Rett Syndrome Patient and Three Human Controls: Mutated Allele Preferential Transcription and In Situ RNA Mapping by Martina Mietto, Silvia Montanari, Maria Sofia Falzarano, Elisa Manzati, Paola Rimessi, Marina Fabris, Rita Selvatici, Francesca Gualandi, Marcella Neri, Fernanda Fortunato, Miryam Rosa Stella Foti, Stefania Bigoni, Marco Gessi, Marcella Vacca, Silvia Torelli, Joussef Hayek, Alessandra Ferlini

“…This patient is part of a cohort of 56 genetically and clinically characterized RTT patients, for whom we provide an overview of the mutation landscape. …”
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Test methods for adhesive polymer compositions in development and quality control for stoma care products on the example of adhesive baseplates (review) by I. A. Sadkovskii, L. A. Korol, A. B. Karabanova, A. V. Korolenko, E. A. Shemetova, I. I. Krasnyuk, G. V. Ramenskaya, M. A. Mandrik

“…Adhesive baseplates, designed to fix ostomy bags and protect the skin of the peristomal area of ostomy patients, are a key element of an ostomy bag or urine bag. The functionality of adhesive baseplates is ensured by a set of their technical characteristics and design features, which makes the choice of appropriate baseplate testing methods an important aspect in the development, production and quality control of these medical devices.Text. …”
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Gut microbiota modulate radiotherapy-associated antitumor immune responses against hepatocellular carcinoma Via STING signaling by Zongjuan Li, Yang Zhang, Weifeng Hong, Biao Wang, Yixing Chen, Ping Yang, Jian Zhou, Jia Fan, Zhaochong Zeng, Shisuo Du

“…Mechanistically, gut microbiome dysbiosis impairs antitumor immune responses by suppressing antigen presentation and inhibiting effector T cell functions through the cGAS–STING–IFN-I pathway. Cyclic-di-AMP – an emerging second messenger of bacteria – may act as a STING agonist and is thus a potential target for the prediction and modulation of responses to RT in HCC patients. …”
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Mo-W₁₈O₄₉/ZnIn₂S₄ Composites Synthesized by Metal Doping for Photocatalytic Hydrogen Evolution by Ruiqin Sun, Yue Liu, Jiamei Yang, Tuoya Wuren, Haochen Duan, Zhibing Tan, Shiyong Yu

“…In this study, ZnIn₂S₄ serves as the primary catalyst carrier, while Mo-W₁₈O₄₉ functions as the cocatalyst supported on the surface of ZnIn₂S₄. …”
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Integrated approach of network pharmacology, molecular docking, and clinical observations in evaluating the efficacy and safety of Bufei Huoxue capsules for pulmonary hypertension... by Wenjun He, Chunli Liu, Xuanyi Li, Bihua Zhong, Qian Jiang, Ning Lai, Yuanhui Xiong, Weici Feng, Yilin Chen, Dansha Zhou, Defu Li, Wenju Lu, Jurjan Aman, Harm Jan Bogaard, Jian Wang, Yuqin Chen

“…Abstract Chronic obstructive pulmonary disease (COPD) is a persistent and progressive disorder characterized by airway or alveolar abnormalities, commonly leading to pulmonary hypertension (PH). …”
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Exploring the performance of GaN trench CAVETs from cryogenic to elevated temperatures by X. Wen, K. Lee, H. Kasai, H. Kasai, M. Noshin, C. Meng, S. Chowdhury

“…The device maintained field effect transistor (FET) functionality after exposure to 773 K, albeit with reduced current. …”
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Cytokine Storm in Pathogenesis of COVID-19 Complications by Olga V. Rasputniak, Tetiana I. Gavrilenko, Olena A. Pidgaina, Liudmyla M. Shnaider, Oleksandr M. Lomakovskyi, Sviatoslav A. Kalashnikov

“…In COVID-19 patients, pyroptosis triggers the release of proinflammatory cytokines and affects macrophage and lymphocyte functions, causing peripheral lymphopenia. Cytokine storm is characterized by a clinical presentation of overwhelming systemic inflammation, hyperferritinemia, hemodynamic instability, and multi-organ failure. …”
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Synthesis and Performance of Epoxy-Terminated Hyperbranched Polymers Based on Epoxidized Soybean Oil by Guang-Zhao Li, Qiuhong Wang, Chongyu Zhu, Shuai Zhang, Fumei Wang, Lei Tao, Youqi Jiang, Qiang Zhang, Wenyan Wang, Rui Han

“…They possess characteristics such as low viscosity, high functionality, and thermal stability, which endow them with broad application potential in materials science and chemical engineering. …”
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California Stress, Trauma, and Resilience Study (CalSTARS) protocol: A multiomics-based cross-sectional investigation and randomized controlled trial to elucidate the biology of AC... by Lauren Y. Kim, Sophia Miryam Schüssler-Fiorenza Rose, Summer Mengelkoch, Daniel P. Moriarity, Jeffrey Gassen, Jenna C. Alley, Lydia G. Roos, Tao Jiang, Arash Alavi, Durga Devi Thota, Xinyue Zhang, Dalia Perelman, Tamar Kodish, Janice L. Krupnick, Michelle May, Katy Bowman, Jenna Hua, Yaping Joyce Liao, Alicia F. Lieberman, Atul J. Butte, Patricia Lester, Shannon M. Thyne, Joan F. Hilton, Michael P. Snyder, George M. Slavich

“…To address these issues, we developed a combined cross-sectional study and randomized controlled trial, called the California Stress, Trauma, and Resilience Study (CalSTARS), to (a) characterize how ACEs influence multisystem biological functioning in adults with all levels of ACE burden and current perceived stress, using multiomics and other complementary approaches, and (b) test the efficacy of our new California Precision Intervention for Stress and Resilience (PRECISE) in adults with elevated perceived stress levels who have experienced the full range of ACEs. …”
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USP29 alleviates the progression of MASLD by stabilizing ACSL5 through K48 deubiquitination by Sha Hu, Zhouxiang Wang, Kun Zhu, Hongjie Shi, Fang Qin, Tuo Zhang, Song tian, Yanxiao Ji, Jianqing Zhang, Juanjuan Qin, Zhigang She, Xiaojing Zhang, Peng Zhang, Hongliang Li

“…Moreover, the effect of USP29 on hepatocyte lipid accumulation and MASLD was dependent on ACSL5. Conclusions USP29 functions as a novel negative regulator of MASLD by stabilizing ACSL5 to promote FAO. …”
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Synthesis, Cytotoxic and Genotoxic Evaluation of Drug-Loaded Silver Nanoparticles with Mebeverine and Its Analog by Mihaela Stoyanova, Miglena Milusheva, Milena Georgieva, Penyo Ivanov, George Miloshev, Natalia Krasteva, Kamelia Hristova-Panusheva, Mehran Feizi-Dehnayebi, Ghodsi Mohammadi Ziarani, Kirila Stojnova, Slava Tsoneva, Mina Todorova, Stoyanka Nikolova

“…<b>Methods:</b> AgNPs were synthesized using a rapid method and functionalized with MBH and its analog. The nanoparticles were characterized using different techniques. …”
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Silicon-based Tubular Micromotor with SERS Traceability and Magnetic–Thermal Dual Responsiveness by Sijie Zhang, Gaoqiang Yin, Zuyao Wang, Lei Wu, Kuo Yang, Ruohu Zhang, Shenfei Zong, Zhuyuan Wang, Yiping Cui

“…Then, a multi-step functionalization process was carried out, the silicon microtubes were modified with Fe3O4 magnetic nanoparticles and gold core–silver shell nanoparticles to enable magnetic controllability and surface-enhanced Raman scattering (SERS) traceability. …”
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Kratom use among ethnobotanical tea bar patrons in Colorado: Subjective drug effects, adverse reactions, and perceived benefits of use by Cianna J. Piercey, Joseph Bunch, Joseph Cameron, Riley Ahern, Isabella Packwood, Carter Bruning, Devin Henry, Jesse Ruehrmund, Katelyn Weldon, Kirsten E. Smith, Hollis C. Karoly

“…Introduction: Kratom use is increasing in the US, yet data characterizing use patterns, risks, and benefits is limited. …”
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Mild opening procedure to obtain open-ended yet long single-wall carbon nanotubes for subsequent filling by Aina Fitó-Parera, Miguel Ángel López Carrillo, Marcel Erwan Tonye, Maksiem Erkens, Pegie Cool, Wim Wenseleers, Salomé Forel, Sofie Cambré

“…Encapsulation of molecules inside the hollow core of single-wall carbon nanotubes (SWCNTs) has become an interesting research field to create new functionalities. To fill the SWCNTs, as-synthesized SWCNTs first need to be opened. …”
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Proinflammatory follicular helper T cells promote immunoglobulin G secretion, suppress regulatory B cell development, and correlate with worse clinical outcomes in gastric cancer by Hong Zhang, Rongxi Yue, Pengfei Zhao, Xuetao Yu, Junguo Li, Guoqing Ma, Jiahong Tang, Lixin Zhang, Liying Feng, Lidong Sun, Zongchang Song, Chunliang Guo, Ning Wang

“…In this study, we investigated the potential involvement of follicular helper T cells in gastric cancer. Functions of follicular helper T subsets were examined in Helicobacter pylori –infected gastric cancer patients and H. pylori –infected but asymptomatic individuals. …”
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Defect Generation and Evolution in Irradiated Epitaxial Films and Heterostructures of Fe3O4 and Cr2O3 by Tiffany C. Kaspar, Maciej O. Liedke, Kayla H. Yano, Jijo Christudasjustus, Hyosim Kim, Yongqiang Wang, Mark E. Bowden, George E. Sterbinsky, Maik Butterling, Eric Hirschmann, Andreas Wagner, Daniel K. Schreiber

“…Abstract The functionality of nuclear structural materials, sensors, and microelectronics in harsh environments such as radiation relies on understanding defect generation and evolution processes in oxide layers. …”
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