A Comparative Study of Deep Reinforcement Learning Algorithms for Urban Autonomous Driving: Addressing the Geographic and Regulatory Challenges in CARLA by Yechan Park, Woomin Jun, Sungjin Lee

“…To evaluate the adaptability of each algorithm to geographical variability and complex traffic laws, scenario-specific reward and penalty functions were carefully designed and incorporated. …”
Get full text

The operational municipal solid waste management policy focuses on identifying waste generation behavior across multiple levels in mega cities, a case study by Hamed Alimoradiyan, Ahmad Hajinezhad, Hossein Yousefi, Mario Giampietro

“…According to this conceptualization, the UWMS functions as an organ within a socio-ecological system, controlling urban metabolism and providing resources and capacity for regional sinks within the larger waste management system. …”
Get full text

Getting back on track after treatment of cancer: A qualitative interview study of cancer survivors' experiences. by Doris van der Smissen, Marjolein Lugtenberg, Manon Enting, Laurens Beerepoot, Floortje Mols, Evelien Brouwers, Dareczka Wasowicz, Margot Joosen

“…Second, survivors experienced challenges with getting back on track such as the impact of impaired physical and cognitive functions, and challenges and uncertainty related to work and finances. …”
Get full text

A high-throughput genetic screen identifies previously uncharacterized Borrelia burgdorferi genes important for resistance against reactive oxygen and nitrogen species. by Meghan E Ramsey, Jenny A Hyde, Diana N Medina-Perez, Tao Lin, Tao Lin, Lihui Gao, Maureen E Lundt, Xin Li, Steven J Norris, Jon T Skare, Linden T Hu

“…B. burgdorferi contains a limited repertoire of canonical oxidative stress response genes, suggesting that novel gene functions may be important for protection of B. burgdorferi against ROS or RNS exposure. …”
Get full text

A single-cell atlas of the Culex tarsalis midgut during West Nile virus infection. by Emily A Fitzmeyer, Taru S Dutt, Silvain Pinaud, Barb Graham, Emily N Gallichotte, Jessica L Hill, Corey L Campbell, Hunter Ogg, Virginia Howick, Mara K N Lawniczak, Erin Osborne Nishimura, Sarah Hélène Merkling, Marcela Henao-Tamayo, Gregory D Ebel

“…The mosquito midgut functions as a key interface between pathogen and vector. …”
Get full text

Strongyloides stercoralis age-1: a potential regulator of infective larval development in a parasitic nematode. by Jonathan D Stoltzfus, Holman C Massey, Thomas J Nolan, Sandra D Griffith, James B Lok

“…In C. elegans, the phosphatidylinositol-3 (PI3) kinase catalytic subunit AGE-1 functions in the insulin/IGF-1 signaling (IIS) pathway to regulate formation of dauer larvae. …”
Get full text

Beam Energy Re-calibration of Beijing HI-13 Tandem Accelerator by LUO Tianpeng1, LIN Chengjian1, 2, MA Nanru1, LI Kangning1, KAN Chaoxin1, WANG Xiaofei1, BAO Yiwen1, YANG Lei1, JIA Huiming1, YANG Feng1, WEN Peiwei1, PANG Tingtao1, CHEN Si1, HUANG Zhijie1, CHANG Chang1, YIN Cheng1, YANG Jionghe1, 2, DUAN Hairui1, ZHU Songxian1, FAN Zerui1, WANG Haorui1, FU Lingyi1, LI Huiyan1, SHI Guangjun1, ZHANG Zihao1, LI Zhi1

“…The product counts from each reaction channel were normalized by the beam-current integrator to obtain the excitation functions. By fitting the excitation functions, the magnetic field corresponding to the resonance peak position can be determined, which in turn allows us to calculate the K of the analyzing magnet. …”
Get full text

Inter-reader agreement and additive benefit of SPECT or SPECT/CT modality with [99mTc]Tc-pertechnetate scintigraphy imaging for the assessment of thyroid nodules in a tertiary care... by Emil Novruzov, Dominik Schmitt, Katalin Mattes-György, Julian Kuhlmann, Mareike Muchalla, Matthias Schott, Christina Antke, Frederik L. Giesel, Eduards Mamlins

“…IRA regarding the target TN functionality among readers was good with k-value of 0.68 (95%CI: 0.59–0.77). …”
Get full text

DEFORMATION OF THE MELODRAMA GENRE IN UKRAINIAN POSTMODERN LITERATURE: IREN ROZDOBUDKO AND NATALIA HURNYTSKA by Olha O. Lilik, Olena V. Sazonova

“…There is a shift in emphasis from dialogues to internal monologues, from plot vicissitudes to character images (there is an emphasis on character images, in particular, female rebels functioning within “formulaic” plots and situations). …”
Get full text

Dolor musculoesquelético y discapacidad del cuadrante superior en estudiantes de instrumentos de cuerda: Un estudio piloto transversal (Musculoskeletal pain and upper quadrant disa... by Ornella Cheuquel Jara, Jetzabel Rodríguez Alegría, Claudio Carvajal-Parodi, Gonzalo Arias-Álvarez, Cristhian Mendoza, Adolfo Soto-Martínez, Francisco Guede-Rojas

“…Neuropathic pain was present in 64.28% of cases. General functionality measured with EGDC was affected in 71.42% of the individuals. …”
Get full text

Big Data Analytics for Uncovering Voxel Connectivity Patterns in Attention Deficit Hyperactivity Disorder by Caraka RE, Supardi K, Gio PU, Isnaniawardhani V, Chen RC, Djatmiko B, Pardamean B

“…The performance of different activation functions—ReLU, Sigmoid, and Tanh—was evaluated within deep neural networks.Results: Several key brain regions, including the Fusiform Gyrus, Thalamus, and Superior Temporal Gyrus, were identified as significant predictors for ADHD. …”
Get full text

Epigenetic modifications in bladder cancer: crosstalk between DNA methylation and miRNAs by Wei Li, Wei Li, Wei Li, Peiyue Luo, Peiyue Luo, Peiyue Luo, Qi Chen, Qi Chen, Qi Chen, Le Cheng, Le Cheng, Le Cheng, Lifeng Gan, Lifeng Gan, Lifeng Gan, Fangtao Zhang, Fangtao Zhang, Fangtao Zhang, Haidong Zhong, Haidong Zhong, Haidong Zhong, Liying Zheng, Biao Qian, Biao Qian

“…Bladder cancer (BC) is a malignant tumor characterized by a high incidence of urinary system diseases. …”
Get full text

Platelet-derived microparticles adoptively transfer integrin β3 to promote antitumor effect of tumor-infiltrating T cells by Mimi Zhou, Yali Feng, Xiaoli Zhang, Jianguo Chen, Naijuan Yao, Shan Fu, Tianzhi Ni, Yi Chen, Fei Xie, Sahasrabda Roy, Jinfeng Liu, Yuan Yang, Yingli He, Yingren Zhao, Nan Yang

“…Additionally, integrin β3 functioned as a positive immunomodulatory molecule to facilitate T-cell infiltration and T helper 1-type immune response in vitro. …”
Get full text

γδT cells, a key subset of T cell for cancer immunotherapy by Jianzhen Lv, Zheng Liu, Xiangting Ren, Siyuan Song, Yan Zhang, Yi Wang, Yi Wang

“…γδT cells represent a unique and versatile subset of T cells characterized by the expression of T-cell receptors (TCRs) composed of γ and δ chains. …”
Get full text

Interaction of blood-entry components, network pharmacology and transcriptomics to elucidate the mechanism of Wentong plaster in treating primary dysmenorrhea by Zongtong Yang, Ziqi Jiao, Cheng Wang, Xiaojing Li, Mengyu Yuan, Zaiyun Sui, Wenhui Wang, Wenjing Hou

“…IntroductionPrimary dysmenorrhea (PD) is characterized by pain during the menstrual cycle, affects women's health. …”
Get full text

Detecting Sleep Apnea with Smart-tech: Scientific Breakthrough or Overhyped Technology? by Aleksandra Głowacka, Paulina Grzeszczuk, Iwona Skorulska, Agnieszka Kalisz, Marta Ignatiuk-Chilkiewicz, Weronika Grywińska, Julia Kozakiewicz, Kamil Kościelecki, Klaudia Mączewska, Patrycja Długozima

“…Sleep disorders can severely impair cognitive functions such as concentration and memory, while also leading to chronic fatigue and emotional instability. …”
Get full text

Perindopril Ameliorates Sodium Valproate-Induced Rat Model of Autism: Involvement of Sirtuin-1, JAK2/STAT3 Axis, PI3K/Akt/GSK-3β Pathway, and PPAR-Gamma Signaling by Anwar M. Alnakhli, Asmaa Saleh, Ahmed M. Kabel, Remon S. Estfanous, Hany M. Borg, Khulud M. Alsufyani, Nesreen M. Sabry, Fatma Alzahraa M. Gomaa, Maaly A. Abd Elmaaboud

“…<i>Background and Objectives:</i> Autism is a developmental disability characterized by impairment of motor functions and social communication together with the development of repetitive or stereotyped behaviors. …”
Get full text

The Relationship Between Physical Activity and Migraines: Research on Prevention and Supportive Treatment by Wiktoria Belcarz, Karolina Kalinowska, Aleksandra Paprocka, Urszula Świrk, Paulina Fijałek, Jan Karczmarz, Marika Gutowska, Magdalena Balwierz, Joanna Orzechowska, Michał Orzechowski

“…Migraine significantly impacts the daily functioning of individuals affected by the condition. …”
Get full text

A microbead-enhanced electrochemical platform for β-amyloid peptide (1–42) detection by Claudia do Amaral Razzino, Claudia do Amaral Razzino, Lívia Flório Sgobbi, Juliana Cancino-Bernardi, Angelica Maria Mazuera Zapata, Clara Cardoso Costa, Valtencir Zucolotto, Lucia Vieira, Anderson Oliveira Lobo

“…Alzheimer’s disease is the most prevalent form of dementia and is primarily characterized by the accumulation of β-amyloid and phosphorylated tau proteins in the brain, along with the degeneration of nerve cells, which leads to impairment of various cognitive functions. …”
Get full text

<i>DBI</i> as a Novel Immunotherapeutic Candidate in Colorectal Cancer: Dissecting Genetic Risk and the Immune Landscape via GWAS, eQTL, and pQTL by Ting Tian, Huan Han, Jingtao Huang, Jun’e Ma, Ruoxi Ran

“…The remaining proteins demonstrated diverse and complex functions within the tumor immune microenvironment, providing novel insights for the development of precision diagnostics and immunotherapeutic strategies.…”
Get full text