Anticholinergic syndrome in the perioperative period (review). Part 1 by O.V. Kravets, V.V. Yekhalov, V.A. Sedinkin, O.V. Pylypenko, D.A. Martynenko

“…Anticholinergic syndrome is a febrile toxidrome characterized by the suppression of cholinergic neurotransmission in muscarinic receptors. …”
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SCRAs with a “Brand” New Look: In Vitro Cannabinoid Activity Profiling of Generic Ban-Evading Brominated Synthetic Cannabinoid Receptor Agonists and their Analogs by M.H. Deventer, M. Persson, C. Norman, H. Liu, M. Connolly, N.N. Daeid, C. McKenzie, H. Green, C.P. Stove

“…Methods: Six new SCRAs were functionally characterized at CB1 and CB2 using 2 distinct activity-based assays, monitoring βarr2 recruitment (NanoBiT® assay) and Ca2+ mobilization (AequoScreen® assay). …”
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Potential Piperolactam A Isolated From Piper betle as Natural Inhibitors of Brucella Species Aminoacyl‐tRNA Synthetase for Livestock Infections: In Silico Approach by Diding Latipudin, Sefren Geiner Tumilaar, Yoga Ramdani, Dudi Dudi, Dikdik Kurnia

“…Aminoacyl‐tRNA synthetases (aaRSs), which have fundamental functions in translation, inhibit this process, stop protein synthesis and ultimately inhibit bacterial growth. …”
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Chemical leachates from car tyre granulates and PET bottles induce toxic effects on Mytilus edulis haemocytes by M. Elisabetta Michelangeli, Sicco H. Brandsma, Maria Margalef, Emelie Forsman, Sebastian Kuehr, Davide Spanu, Tânia Gomes

“…These findings indicated that leachates from CTG and PET can impair haemocytes functions in bivalves through mechanisms such as oxidative stress, membrane depolarization, and disrupted metabolic processes, underscoring their toxic potential. …”
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Nuclear basket nucleoporin MoNup50 is essential for fungal development, pathogenicity, and autophagy in Magnaporthe oryzae by Ying-Ying Cai, Xue-Ming Zhu, Muhammad Noman, Jing Wang, Zhong-Na Hao, Yan-Li Wang, Lin Li, Xiao-Hong Liu, Jian-Ping Lu, Jiao-Yu Wang, Fu-Cheng Lin

“…In this study, we functionally characterized MoNup50, a nuclear pore-associated protein. …”
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Divergent WNT signaling and drug sensitivity profiles within hepatoblastoma tumors and organoids by Thomas A. Kluiver, Yuyan Lu, Stephanie A. Schubert, Lianne J. Kraaier, Femke Ringnalda, Philip Lijnzaad, Jeff DeMartino, Wouter L. Megchelenbrink, Vicky Amo-Addae, Selma Eising, Flavia W. de Faria, Daniel Münter, Marc van de Wetering, Kornelius Kerl, Evelien Duiker, Marius C. van den Heuvel, Vincent E. de Meijer, Ruben H. de Kleine, Jan J. Molenaar, Thanasis Margaritis, Hendrik G. Stunnenberg, Ronald R. de Krijger, József Zsiros, Hans Clevers, Weng Chuan Peng

“…Gene regulatory network analysis reveals enrichment of regulons related to hepatic functions such as bile acid, lipid and xenobiotic metabolism in the fetal subtype but not in the embryonal subtype. …”
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Distorted time window for sensorimotor integration and preserved time window for sense of agency in patients with post-stroke limb apraxia by Satoshi Nobusako, Satoshi Nobusako, Rintaro Ishibashi, Takaki Maeda, Sotaro Shimada, Shu Morioka, Shu Morioka

“…Limb apraxia is a cognitive-motor disorder typically resulting from left hemisphere stroke, characterized by an inability to perform skilled limb movements despite intact motor and sensory functions. …”
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Synthesis of Dendritic Oligo‐Glycerol Amphiphiles with Different Hydrophobic Segments to Improve their Performance as Nanocarriers by Pooja Kumari, Christian Zoister, Natalie Hanheiser, Dr. Hesam Makki, Dr. Boris Schade, Dr. Mathias Dimde, Katharina Achazi, Dr. Sumit Kumar, Prof. Dr. Rainer Haag, Dr. Abhishek K. Singh

“…These non‐ionic amphiphiles are functionalized with different hydrophobic segments to investigate the contribution of the same towards their guest transport behaviour. …”
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Bromophenols in Red Algae: Exploring the Chemistry and Uncovering Biological Benefits of These Unknown Compounds by Paula Barciela, Maria Carpena, Ana Perez-Vazquez, Aurora Silva, Ana Olivia S. Jorge, Miguel A. Prieto

“…Bromine substitution not only confers specific chemical properties but also plays an important role in the ecological functions of bromophenols by inducing increased lipophilicity, which affects solubility and reactivity, an adaptive response to external conditions. …”
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Postoperative Cognitive Disorder- what do we know about risk factors and prevention? A Systematic Review by Antonina Drzewiecka, Artur Drzewiecki, Wiktor Korczak, Maria Madejska, Aleksandra Rudzka, Monika Gaszyńska, Wojciech Falkowski, Anna Krysińska, Weronika Woźniak, Jakub Magielski

“… Introduction Postoperative Cognitive Dysfunction (POCD) is a significant health complication that affects mental processes, particularly in elderly patients after surgery. It is characterized by impaired memory, attention, and executive functions, leading to prolonged hospitalization and increased mortality. …”
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VSMCs in atherosclerosis: Implications on the role of inflammation and extracellular matrix remodelling by Suha Jarad, Govind Gill, Peter Amadi, Hong-mei Gu, Da-wei Zhang

“…Therefore, the main functions of VSMCs in atherosclerosis will be influenced, including the production of extracellular matrix (ECM) proteins and the maintenance of atherosclerotic plaque stability. …”
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Interaction between Human Serum Albumin and Different Anatase TiO2 Nanoparticles: A Nano-bio Interface Study by Viviana Vergaro, Claudia Carlucci, Mariafrancesca Cascione, Caterina Lorusso, Francesca Conciauro, Barbara Federica Scremin, Paolo Maria Congedo, Giuseppe Cannazza, Cinzia Citti, Giuseppe Ciccarella

“…In this investigation, differently shaped and surface functionalized TiO2 anatase nanoparticles and human serum albumin (HSA) were selected to study protein- nanoparticles interaction both in a solution and on flat surfaces, thereby mimicking a medical device. …”
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Resveratrol Protects against Sepsis-Associated Encephalopathy and Inhibits the NLRP3/IL-1β Axis in Microglia by Da-ming Sui, Qun Xie, Wen-jing Yi, Sahil Gupta, Xi-ya Yu, Jin-bao Li, Jun Wang, Jia-feng Wang, Xiao-ming Deng

“…Spatial learning memory functions were evaluated by Morris water maze testing. …”
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Magnetic Bifunctional Ru-Enzyme Catalyst Allows for Sustainable Conversion of Cellulose Derivative to D-Sorbitol by Boris B. Tikhonov, Daniil R. Lisichkin, Alexandrina M. Sulman, Alexander I. Sidorov, Alexey V. Bykov, Yury V. Lugovoy, Alexey Y. Karpenkov, Lyudmila M. Bronstein, Valentina G. Matveeva

“…The nanobiocatalyst is based on magnetic nanoparticle aggregates (MNAs) functionalized with chitosan (CS) cross-linked by tripolyphosphate (TPP). …”
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Does Intercity Transportation Accessibility Matter? Its Effects on Regional Network Centrality in South Korea by Sangwan Lee, Jeongbae Jeon, Kuk Cho, Junhyuck Im

“…First, the Seoul Metropolitan Area emerges as the dominant mobility hub, with Busan, Daegu, and Daejeon functioning as secondary centers, reflecting a polycentric urban configuration. …”
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Altered glucose metabolism in default mode network and prefrontal circuit in patients with Kallmann syndrome by Chunqing Zhou, Xueying Wang, Meichao Men, Xiaoping Yi, Ke Cao, Weidan Pu, Marcus Hacker, Xiang Li, Min Zhao

“…Conclusion Patients with KS exhibited a distinct hypermetabolism pattern in the DMN-prefrontal circuit, which functionally bridges neuroendocrine dysfunction and reproductive health anxiety.…”
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A myzozoan-specific protein is an essential membrane-anchoring component of the succinate dehydrogenase complex in Toxoplasma parasites by Soraya M. Zwahlen, Jenni A. Hayward, Capella S. Maguire, Alex R. Qin, Giel G. van Dooren

“…Succinate dehydrogenase (SDH) is a protein complex that functions in the tricarboxylic acid cycle and the electron transport chain of mitochondria. …”
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Melting mode-driven processing diagram for nanoparticle-enhanced high-strength aluminum alloy processed by laser powder bed fusion by Ali Rezaei, Mohsen K. Keshavarz, John Barnes, Mihaela Vlasea

“…Significant knowledge gaps persist in understanding the effects of melting modes, the functionality of nanoparticles, and compositional variations in this material system. …”
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Sagittal Plane Kinematic Deviations and Spatio-Temporal Gait Characteristics in Children with Idiopathic Toe Walking: A Comparative Analysis Using Statistical Parametric Mapping by Rocio Pozuelo-Calvo, Almudena Serrano-Garcia, Yolanda Archilla-Bonilla, Angel Ruiz-Zafra, Manuel Noguera-Garcia, Kawtar Benghazi-Akhlaki, Miguel Membrilla-Mesa, Carla DiCaudo, Jose Heredia-Jimenez

“…While spatio-temporal parameters often remain within normal ranges, subtle but clinically significant kinematic deviations may underlie compensatory mechanisms that sustain gait functionality. This study aims to evaluate spatio-temporal and sagittal plane kinematic differences between children with ITW and typically developing peers using Statistical Parametric Mapping (SPM). …”
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Microbial life-history strategies and genomic traits between pristine and cropland soils by Dan He, Zhongmin Dai, Shuxun Cheng, Haojie Shen, Jiahui Lin, Kankan Zhao, Jorge L. Mazza Rodrigues, Yakov Kuzyakov, Jianming Xu

“…ABSTRACT Microbial life-history strategies [inferred from ribosomal RNA operon (rrn) gene copy numbers] and associated genomic traits and metabolism potentials in soil significantly influence ecosystem properties and functions globally. Yet, the differences in microbial strategies and traits between disturbed (cropland) and pristine soils, along with their dominant driving factors, remain underexplored. …”
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