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18661
O-GlcNAcylation on serine 40 of histone H2A promotes proliferation and invasion in triple-negative breast cancer
Published 2025-03-01“…Abstract Triple-negative breast cancer (TNBC) is characterized by resistance to conventional treatment and a poor prognosis. …”
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18662
Seismic prediction technology for thin sandstone reservoir of Dainan Formation in Majiazui Oilfield
Published 2024-02-01“…Dainan Formation in Majiazui Oilfield is characterized by developed fractures and is primarily composed of structural-lithologic reservoirs. …”
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18663
Unraveling the molecular mechanisms of vitamin deficiency in Alzheimer's disease pathophysiology
Published 2025-06-01“…Vitamins, a crucial dietary supplement, regulate various physiological functions and maintain neuronal health, energy metabolism, and antioxidant defence. …”
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18664
Gaussian Process with Vine Copula-Based Context Modeling for Contextual Multi-Armed Bandits
Published 2025-06-01“…Context vectors are generated using Gaussian and vine copulas to capture nonlinear dependencies, while arm-specific reward functions are modeled via GP regression with Beta-distributed targets. …”
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18665
Retrovolution: HIV-driven evolution of cellular genes and improvement of anticancer drug activation.
Published 2012-08-01“…In evolution strategies aimed at isolating molecules with new functions, screening for the desired phenotype is generally performed in vitro or in bacteria. …”
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18666
FinTech and DeFi: Directions for Digital Adaptation of Banks
Published 2025-07-01“…The article is devoted to the study of decentralised finance (DeFi) as a new stage of digitalisation of the financial sector, characterized by the rejection of centralised intermediation in favor of protocol-controlled mechanisms. …”
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18667
Epistatic roles for Pseudomonas aeruginosa MutS and DinB (DNA Pol IV) in coping with reactive oxygen species-induced DNA damage.
Published 2011-04-01“…Models discussing roles for MutS and DinB functionality in DNA damage-induced mutagenesis, particularly during CF airway colonization and subsequent P. aeruginosa pathoadaptation are discussed.…”
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18668
An Architectural Approach to Neighborhood Design in The Quarry Road Informal Settlement in Durban
Published 2024-04-01“…Creating well-functioning and supportive neighborhoods within these settlements is crucial for improving the living conditions and livelihoods of those living there. …”
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18669
A digital twin based forecasting framework for power flow management in DC microgrids
Published 2025-02-01“…Abstract The ability to forecast system conditions is integral to the definition and functionality of digital twins. While forecasting methods have been explored for use in digital twin systems, the integration of feedback mechanisms for real-time forecasting and in-situ decision-making in DC microgrids has not been extensively investigated. …”
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18670
Advanced Nanotechnology-Enhanced Delivery Systems for Precision Targeted Herbicide Application in Sustainable Crop Protection
Published 2025-01-01“…Controlled release and targeted drug delivery is enabled by herbicide delivery from these materials that are chosen for high surface area and customizable functionalities. Particle Swarm Optimization (PSO) and Finite Element Analysis (FEA) is used to design and fabricate nanocarrier so as to optimize these critical parameters, namely size, shape and surface modification. …”
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18671
For a Semiotic Approach to Generative Image AI
Published 2025-04-01“…This article analyzes the semiotic functioning of Midjourney and DALL•E, two generative AI models capable of producing images out of natural language prompts. …”
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18672
Seasonality and interannual variability of an Arctic marine time series, IsA
Published 2025-01-01“…Microbial eukaryotes are diverse and essential to the functioning of marine ecosystems, thus environmental perturbations altering their communities influence the entire ecosystem. …”
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18673
Accounting Development in the System of Transition to the New Standards of Financial Security of a Commercial Bank
Published 2018-09-01“…So, there was the comparative analysis of the core performance indicators characterizing the financial security mainly associated with the functioning of the financial sector of the national economy and it also showed the gaps existing in the Russian Federation system as the basis for further development of the simplified system of statistical accounting of financial security for the banks in the Russian Federation.…”
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18674
Epithelial and stromal microRNA signatures of columnar cell hyperplasia linking Let-7c to precancerous and cancerous breast cancer cell proliferation.
Published 2014-01-01“…Let-7c were among the identified downregulated epithelial miRNAs and its functions were delineated in unique CCH derived cells and breast cancer cell line MCF-7 suggesting anti-proliferative traits potentially due to effects on Myb and ERα. …”
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18675
Cerebrospinal fluid biomarker candidates associated with human WNV neuroinvasive disease.
Published 2014-01-01“…On the basis of their known biological functions, several of these proteins were associated with inflammatory response. …”
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18676
Enhanced long-term corrosion resistance and self-healing of epoxy coating with HQ-Zn-PA nanocomposite
Published 2025-03-01“…Polyaniline (PA) contributes anodic protection and forms a barrier layer, while the chelation of zinc by 8-hydroxyquinoline-5-sulfonic acid (HQZn) improves PA compatibility within the polymer matrix and functions as an organic corrosion inhibitor. This dual action strengthens corrosion resistance through both anodic and cathodic protection mechanisms. …”
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18677
TMS-EEG evidence links random exploration to inhibitory mechanisms in the dorsolateral prefrontal cortex
Published 2025-05-01“…To investigate this, we combined transcranial magnetic stimulation (TMS) with electroencephalography (EEG) to directly assess cortical excitatory and inhibitory functions. Twenty-five healthy participants completed the Horizon Task, a behavioral paradigm designed to dissociate directed and random exploration, and after the task, they received single-pulse TMS over the DLPFC. …”
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18678
Multiple-Input Multiple-Output Synthetic Aperture Radar Waveform and Filter Design in the Presence of Uncertain Interference Environment
Published 2024-11-01“…In order to improve the convergence performance of ADMM, the difference in convex functions (DC) programming is applied to the ADMM iterations framework to solve the problem of waveform energy inequality constraint. …”
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18679
A Krüppel-like factor establishes cellular heterogeneity during schistosome tegumental maintenance.
Published 2025-03-01“…Thus, klf4 is critical for regulating the balance between different cell populations within the tegumental progenitor pool and thereby influences tegumental production dynamics and the fine-tuning of the molecular identity of the mature tegument. Understanding the functions of distinct populations of cells within the tegumental syncytium is expected to provide insights into parasite defense mechanisms and new avenues for combatting the disease these worms cause.…”
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18680
Bridging ADHD and Metabolic Disorders: Insights into Shared Mechanisms and Clinical Implications
Published 2025-05-01“…Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by inattention, impulsivity and/or hyperactivity. …”
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