Activation of the Innate Immune Checkpoint CLEC5A on Myeloid Cells in the Absence of Danger Signals Modulates Macrophages’ Function but Does Not Trigger the Adaptive T Cell Immune Response by Milena J. Tosiek, Kerstin Groesser, Anton Pekcec, Monika Zwirek, Gavuthami Murugesan, Eric Borges

“…In this study, we determined CLEC5A receptor expression on different macrophage subsets (in vitro and ex vivo) and the functional consequences of its activation in aseptic conditions. …”
Get full text

Adaptive Fixed-Time Practically Tracking Control for n-Link Flexible-Joint Manipulator With Input Quantization and Input Delay via Command Filter-Based Approach by Rongyang Qiu, Meizhen Xia, Jiu Zhang, Chao Ma

Get full text

A solution for flexible adaption of network services in mobile edge computing by Bohao FENG, Huachun ZHOU

Get full text

Recent advances in functional design of nanocellulose and their intelligent application by Yan Lv, Qian Li, Weidong Yang, Zhen Zhang, Yan Li

“…As an abundant and sustainable material, nanocellulose exhibits properties such as high strength, high modulus, light weight, surface rich in functional groups, and biodegradability. These properties allow it to be chemically or physically modified to confer conductivity, magnetism, or other functionalities, thus showing great promise in the development of self-adaptive materials. …”
Get full text

Immunomodulatory function of chitosan is dependent on complement receptor 3 by Jeanette Wagener, Xiaowen Wang, Katharina L. Becker, Vishu Aimanianda, Isabel Valsecchi, Mark S. Gresnigt, Mihai G. Netea, Jean-Paul Latge, Neil A.R. Gow, Frank L. van de Veerdonk

Get full text

MYOCARDIAL FUNCTION DYNAMICS IN PATIENTS WITH ACUTE CORONARY SYNDROME by V. T. Dolgikh, A. V. Toropov, A. V. Ershov

“…It was demonstrated that ACS with ST elevation was associated with reduced myocardial functional reserve and activation of adaptive mechanisms supporting adequate blood flow. …”
Get full text

Blurred Image Restoration with Unknown Point Spread Function by ghada sabah karam

“…Most of existing blind deconvolution research concentrates at recovering a single blurring kernel for the entire image. We proposed adaptive blind- non reference image quality assessment method for estimation the blur function (i.e. point spread function PSF) from the image acquired under low-lighting conditions and defocus images using Bayesian Blind Deconvolution. …”
Get full text

Reconstruction of Piecewise Smooth Functions Based on Fourier Extension by Xusheng Li, Zhenyu Zhao, Xianzheng Jia

“…This paper proposes a hierarchical Fourier extension framework for the accurate reconstruction of piecewise smooth functions with mixed-order singularities. To address key challenges in spectral approximation–namely boundary-induced artifacts, instability in edge detection, and loss of accuracy near discontinuities–the method integrates three main components: (1) boundary-focused Fourier extensions that isolate endpoint effects while preserving internal structures; (2) a multi-stage edge detection strategy combining spectral mollifiers and coordinate transformations to identify discontinuities in function values and their derivatives; (3) adaptive domain partitioning followed by localized Fourier extensions to retain spectral accuracy on smooth segments. …”
Get full text

Tailored knowledge distillation with automated loss function learning. by Sheng Ran, Tao Huang, Wuyue Yang

Get full text

β-Glucan Subverts the Function of Myeloid Cells in Neonates by Yingying Chen, Hui Li, Lin Zhu, Quan Yang, Jie Zhou

“…Here, we found that β-glucan did not affect the frequencies and numbers of myeloid cells in the spleen and bone marrow from neonates. Functional assay revealed that β-glucan from neonates compromised the immunosuppressive function of immature myeloid cells, which were myeloid-derived suppressor cells (MDSCs). …”
Get full text

Molecules that inhibit T-cell functions: cytochemical localization and shuttling by G Santoro, G Anastasi, D Saverino, C Puri, D Zarcone, C Tacchetti, E Ciccone, CE Grossi

“…Adaptive immune responses to antigens are mediated by specific receptors expressed on B cells (BCR’s) and T cells (TCR’s). …”
Get full text

Prototype of Mobile Meter Waveband Radar with Improved Functionality by I. S. Sadovskiy, Y. Y. Bobkov, I. Y. Malevich

“…Actual stage of meter waveband radar evolution is the design of mobile radar with improved surveillance functions, as well as signal generation and processing. …”
Get full text

Interpreting insect behavior through the lens of executive functions by Bartosz Baran, Michał Obidziński, Mateusz Hohol

“…Here, we propose a new perspective: interpreting insect behavior through the lens of executive functions (EF). EF refers to a set of cognitive processes enabling behavioral control in situations requiring goal-directed action or adaptation to demanding conditions. …”
Get full text

Understanding How Minerals Contribute to Optimal Immune Function by Alina Stefanache, Ionut-Iulian Lungu, Ioan-Adrian Butnariu, Gabriela Calin, Cristian Gutu, Constantin Marcu, Carmen Grierosu, Elena Roxana Bogdan Goroftei, Letitia-Doina Duceac, Marius Gabriel Dabija, Florina Popa, Daniela Damir

“…This review emphasizes the crucial significance of minerals in promoting optimal functioning of the immune system. It investigates the indispensable minerals required for immune system function and the regulation of inflammation. …”
Get full text

Genetics of SLE: Functional Relevance for Monocytes/Macrophages in Disease by Jennifer C. Byrne, Joan Ní Gabhann, Elisa Lazzari, Rebecca Mahony, Siobhán Smith, Kevin Stacey, Claire Wynne, Caroline A. Jefferies

“…Particular attention will be paid to the functional consequences these genetic associations have for disease susceptibility or pathogenesis.…”
Get full text

Multimodal Function of Mesenchymal Stem Cells in Psoriasis Treatment by Jiaxin Ou, Ziqing Li, Danni Yao, Chuanjian Lu, Xiang Zeng

“…In this paper, the role of mesenchymal stem cells in skin homeostasis, the pathogenesis of psoriasis, and the multimodal function of using mesenchymal stem cells in the treatment of psoriasis are reviewed.…”
Get full text

Pattern recognition receptors: function, regulation and therapeutic potential by Ruochan Chen, Ju Zou, Jiawang Chen, Xiao Zhong, Rui Kang, Daolin Tang

Get full text

Macrophages: Subtypes, Distribution, Polarization, Immunomodulatory Functions, and Therapeutics by Mengyuan Peng, Niannian Li, Hongbo Wang, Yaxu Li, Hui Liu, Yanhua Luo, Bao Lang, Weihang Zhang, Shilong Li, Liujun Tian, Bin Liu

“…ABSTRACT Macrophages are heterogeneous immune cells with diverse subtypes and tissue‐specific distributions, displaying dynamic polarization states that critically govern their immunomodulatory functions and responses to environmental cues. As key regulators of innate and adaptive immunity, they originate from either embryonic progenitors or bone marrow‐derived monocytes and exhibit remarkable plasticity in response to microenvironmental cues. …”
Get full text

Collaborating with the Enemy: Function of Macrophages in the Development of Neoplastic Disease by Andrzej Eljaszewicz, Małgorzata Wiese, Anna Helmin-Basa, Michal Jankowski, Lidia Gackowska, Izabela Kubiszewska, Wojciech Kaszewski, Jacek Michalkiewicz, Wojciech Zegarski

“…This paper characterizes the function of macrophages in the development of neoplastic disease.…”
Get full text

GAMMA DELTA (γδ) T CELLS: ORIGIN, PHENOTYPE, FUNCTIONS by Dmitry Sokolov

“…AbstractThe primary function of γδT cells is to regulate the responses of innate and adaptive immune systems. …”
Get full text