Upstream therapy of reperfusion disorders of hemodynamics, rhythm and conduction in patients with acute myocardial infarction with diabetes mellitus and metabolic syndrome (second... by M.I. Shved, I.O. Yastremska, R.M. Ovsiychuk, L.P. Martyniuk, O.A. Prokopovych, Ya.M. Kitsak

“…In patients with STEMI combined with T2DM and MS, hyperglycemia, insulin resistance and severe abnormalities of morphological and functional parameters of the heart with its systolic-diastolic dysfunction are observed at baseline, which are triggers of the complicated course of this pathology, with the deve­lopment of heart failure syndrome, rhythm and conduction disorders. …”
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Safety of Extended Sedation with Sevoflurane in Patients with Severe Traumatic Brain Injury by D. R. Safiullin, A. K. Shabanov, A. A. Grin, R. A. Cherpakov, A. K. Evseev, A. I. Evdokimov, S. S. Petrikov, O. A. Grebenchikov

“…In conditions of increased sensitivity of damaged brain tissue to disruption of homeostasis, it is important to achieve stabilization of the vital functions of the body as soon as possible. Given the excess afferent impulse, adequate sedation and analgesia are an integral component of intensive care for patients with traumatic brain injury. …”
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MYOCARDITIS AS A LEGITIMATE PHENOMENON IN NON-COMPACTION MYOCARDIUM: DIAGNOSTICS, MANAGEMENT AND INFLUENCE ON OUTCOMES by O. V. Blagova, E. V. Pavlenko, N. V. Varionchik, A. V. Nedostup, V. P. Sedov, Е. A. Kogan, V. А. Zaydenov, А. G. Kupriyanova, A. Е. Donnikov, V. V. Kadochnikova, N. V. Gagarina, E. A. Mershina, V. Е. Sinitsyn, М. Е. Polyak, E. V. Zaklyazminskaya

“…DNA-diagnostics was performed by NGS method with further Senger sequencing. …”
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Factores de riesgo para la sobrecarga en cuidadores informales de personas mayores con demencia: una revisión rápida de las últimas evidencias by Carmen Maté-Real, Francisco Rivas-García, Rosa López-Mongil, Carlos Luis-Pérez, Virtudes Niño-Martín, Ángela Hernández Ruiz

“…It is characterized by the loss of memory or other mental functions, which incapacitates patients and requires care from other people, the informal caregivers. …”
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Integrated Network Analysis to Identify Key Modules and Potential Hub Genes Involved in Bovine Respiratory Disease: A Systems Biology Approach by Aliakbar Hasankhani, Abolfazl Bahrami, Abolfazl Bahrami, Negin Sheybani, Farhang Fatehi, Roxana Abadeh, Hamid Ghaem Maghami Farahani, Mohammad Reza Bahreini Behzadi, Ghazaleh Javanmard, Sadegh Isapour, Hosein Khadem, Herman W. Barkema

“…After identifying respective modules by the two mentioned methods of WGCNA, functional enrichment analysis was performed to extract the modules that are biologically related to BRD. …”
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Study of the Effectiveness of Drugs Based on Molecular Complexes of Adenosine-polymer on the Model of Thermal Burn by E. D. Semivelichenko, A. A. Ermolaeva, V. V. Ponomarenko, A. V. Novoselov, G. A. Plisko, D. Yu. Ivkin, V. G. Antonov, V. E. Karev, I. A. Titovich, A. V. Eremin

“…Potentiometric titration of the functional groups of the VP copolymer was performed using a PP-20 pH meter (Sartorius AG, Germany). …”
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Efficacy and safety of Chinese botanical drug Si Shen Wan in irritable bowel syndrome: a meta-analysis and trial sequential analysis of randomized controlled trials by Qian Liu, Zongming Shi, Yang Jiang, Tao Zhang, SiJing Du, Yemei Gao

“…Background and ObjectivesIrritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders (FGIDs), characterized by complex pathogenesis, prolonged disease duration, frequent recurrence, and a significant impact on patients’ quality of life. …”
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Clinical and laboratory significance of soluble claudin-5 and VEGF in ovarian cancer by N. E. Kushlinskii, S. E. Kulikova, F. A. Gugnin, S. Yu. Nezhdanova, A. N. Gratchev, D. O. Utkin, D. A. Tsekatunov, I. B. Ryzhavskaya, D. N. Kushlinskiy, E. S. Gershtein, I. S. Stilidi

“…In addition to their physiological functions, claudin 5 and VEGF play an important role in pathogenesis of various diseases including malignant neoplasms.Aim. …”
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Multi-omics analysis unveils the predictive value of IGF2BP3/SPHK1 signaling in cancer stem cells for prognosis and immunotherapeutic response in muscle-invasive bladder cancer by Yaobang Wang, Wuyue Song, Chao Feng, Shulin Wu, Zezu Qin, Tao Liu, Yu Ye, Rong Huang, Yuanliang Xie, Zhong Tang, Qiuyan Wang, Tianyu Li

“…The upregulated expression of IGF2BP3 in CD274 + ALDH + CSC-like cells, which was associated with poor clinical prognosis, was analyzed by bulk RNA-sequencing data from an in-house cohort. The functional role of IGF2BP3 was determined through cell proliferation, colony formation, cell apoptosis and sphere formation assays. …”
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The impact of renal tubulointerstitial dysfunction on the early and long-term prognosis in chronic heart failure patients with preserved left ventricular ejection fraction by V. V. Syvolap, V. A. Lysenko

“…To study the dependence of the early-term (1 year) and long-term (5 years) prognosis in patients with chronic heart failure (CHF) of ischemic origin with preserved left ventricular ejection fraction (LVEF) depending on renal tubulointerstitial functional disorders. Materials and methods. The study involved 88 patients (men – 46.6 % (n = 41); women – 53.4 % (n = 47)) with CHF of ischemic origin, stage II A–B, stage II–IV according to NYHA, 67 % (n = 59) with sinus rhythm, and 33 % (n = 29) with atrial fibrillation. …”
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Revisión de artrodesis subtalar por no unión: a propósito de un caso by Gregorio Verschae, MD, Valentín Val, MD, Vicente Alba, MD, Andrés Cáceres, MD, Sebastián Pavez, MD, Nicolás Cid, MD

“…Finally, the implementation of well-structured diagnostic and therapeutic algorithms is crucial to improve functional outcomes and ensure successful bone fusion.…”
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A new method of assessing microcirculation of the central retina in patients with different stages of diabetic macular edema in type 2 diabetes by S.A. Suk, S.Yu. Mogilevskyy, M.I. Kovtun, B.B. Zhupan

“…Optical coherence tomography angiography is a non-invasive technique that allows for visualization of retinal vascular plexus layers, quantification of microvascular parameters and correlation with functional and morphological data. Research aimed at identifying early preclinical biomarkers of micro­vascular abnormalities in the diabetic retina is very important, as early treatment is associated with better outcomes. …”
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[Translated article] Risk factors for complications in total hip arthroplasty by L.A. Hoyos-Velasco, J.C. Palacio, W.P. Stangl, C.L. Chacón-Castillo, V. Palacio-Aragón, J.P. Pulgarín

“…Introduction and objective: Hip arthroplasty represents a significant advancement in the treatment of refractory chronic joint pain, improving quality of life and functionality. The objective of this study is to identify the risk factors associated with local and systemic complications in patients treated with total hip arthroplasty. …”
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Living and living with nature. A need of today's population for the common good by Manuel Gregorio Loza-Murguia

“…We should ask ourselves, if someday this will stop, and if those who perform these acts from a desk, or those who do it themselves, are the guilty ones, then the question is, do we want to live, and let future generations live, or will they only continue with the extraction of wealth. …”
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Comparison of clinical efficacy between Percutaneous Endoscopic Large channels nerve decompression through Translaminar approach and Percutaneous Endoscopy Conventional channels ne... by Junlin Liu, Qingquan Kong, Junsong Ma, Pin Feng, Bin Zhang

“…There was no statistically significant difference in functional scores between the two groups at each follow-up time point (p > 0.05). …”
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Immune microenvironment of Epstein-Barr virus (EBV)-negative compared to EBV-associated gastric cancers: implications for immunotherapy by Ke Xu, Qingfeng Zhu, Suzanne L Topalian, Robert A Anders, Janis M Taube, Mark Yarchoan, Keziban Ünsal-Kaçmaz, Logan L Engle, Tracee L McMiller, Sepideh Besharati, Junghwa Lee, Feriyl Bhaijee, Alan E Berger

“…In contrast, EBV(−) tumors overexpressed several functionally-related gene groups associated with myeloid cells (CD163, IL1A, NOS2, RIGI), immunosuppressive cytokines/chemokines (CXCL2, CXCR4, IL10, IL32), coinhibitory molecules (HAVCR2/TIM-3 and VSIR/VISTA), and adenosine pathway components (ENTPD1/ CD39 and NT5E/CD73). …”
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Developments in Legal Education: Beyond the Primary School Model by William Twining

“…Two other recent publications perform similar functions for legal scholarship: the now venerable Modern Law Review marked its fiftieth birthday with an illuminating survey of the state of legal scholarship in the common law world; this exhibits the wry acceptance of lowering of sights by an ageing radical. …”
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Does Mirabegron the β3 Agonist Frequently Used in the Treatment of Overactive Bladder Really Affect the Respiratory System Negatively ? A Prospective Study by Şenol Adanur, Ahmet Gedik, Ömer Araz, Elif Yılmazel Ucar, Kadir Ozmen, Fatih Akkaş, Tugay Aksakalli, Adem Utlu, Ahmet Cinislioğlu

“…Spirometry and body plethysmography were performed to objectively evaluate the respiratory functions of patients with OAB.ResultsThe spirometry and body plethysmography showed that the FVC value was 102.51 ± 16.99 L before, 101.77 ± 14.17 L at the first month, and 100.52 ± 15.98 L at the third month after mirabegron treatment. …”
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Recurrent adenoid cystic carcinoma of the left upper palate accompanied by massive maxillary hemorrhage: a case report and literature review by ZHANG Wangru, CHEN Yuanyuan, LI Zhiping, MENG Jian

“…An emergency tracheotomy was performed to relieve the obstruction of the patient’s respiratory tract, and a red blood cell suspension was transfused to address the hemorrhagic shock. …”
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Artificial plasticenta: how polystyrene nanoplastics affect in-vitro cultured human trophoblast cells by Antonio Ragusa, Loredana Cristiano, Pierluigi Di Vinci, Giuseppe Familiari, Stefania Annarita Nottola, Guido Macchiarelli, Alessandro Svelato, Caterina De Luca, Denise Rinaldo, Isabella Neri, Fabio Facchinetti

“…This would lead to ER and mitochondrial stress, impairing mitochondria/ER functions and oxidative stress, thus activating the apoptotic pathway and suggesting that PS-NPs could act as a cell stressor, leading to the death of cells. …”
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