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46621
Social Support, Quality of Life, and Financial Toxicity Among Patients with Hepatocellular Carcinoma
Published 2025-08-01“…The comprehensive score for financial toxicity (COST) was used to assess financial toxicity, the Functional Assessment of Cancer Therapy-Hepatobiliary (FACT-Hep) was used to assess quality of life (QOL), and the Social Support Rating Scale (SSRS) was used to assess social support. …”
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46622
Introducing the dataset for measuring centrality for sustainability—A case study of Pecinci municipality, SerbiaMendeley DataMendeley Data
Published 2025-08-01“…The current theories and practices of planning central activities in Serbia primarily rely on functional factors of network flow. However, this approach aims to enhance the current practice of data utilisation for the sustainable development of central activities and integrative central places. …”
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46623
Daily Mobility in Metropolitan Areas
Published 2024-06-01“…These include, for example, the locations where these activities are performed, the socioeconomic background of those performing such activities and the distribution of university facilities within a metropolis which has a particular and distinctive topography. …”
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46624
Genome-wide identification and expression of the HB gene family during overwintering in Korla pear (Pyrus sinkiangensis)
Published 2025-01-01“…Comprehensive analyses were performed, including phylogenetic relationships, chromosomal localization, gene structure, promoter cis-acting elements and family-wide collinearity. …”
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46625
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46626
Conserving biodiversity, carbon, and community values in a fragmented landscape
Published 2025-07-01“…Biodiversity analysis was performed using open source software, which was used to calculate biodiversity indices (species richness, Shannon-Wienner diversity, and Simpson diversity). …”
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46627
IL-28A/IL-10Rβ axis promotes angiogenesis via eNOS/AKT signaling and AP-1/NF-κB/MMP-2 network by regulating HSP70-1 expression
Published 2025-07-01“…Gene expression changes in HUVECs following IL-28A treatment were analyzed by NGS. The functional role of HSP70-1 and IL-10Rβ in IL-28A-induced angiogenic responses was evaluated using PCR and siRNA knockdown. …”
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46628
Genome-wide association study of post COVID-19 syndrome in a population-based cohort in Germany
Published 2025-05-01“…The SNP is located in a region including the NEK6, PSMB7 and ADGRD2 genes which, however, does not immediately suggest an etiological connection to PCS. As regards functional plausibility, variants of a possible effect mapped to the olfactory receptor gene region (lead SNP rs10893121 at position chr11:123,854,744; p = 2.5 × 10− 6). …”
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46629
Serum proteomics of adults with acute liver failure provides mechanistic insights and attractive prognostic biomarkers
Published 2025-05-01“…Single-cell RNAseq data mapped biomarkers to cells of origin; functional enrichment analysis provided mechanistic insights. …”
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46630
Regulatory roles of an sRNA derived from the 5´ UTR and sequence internal to lapA in Pseudomonas aeruginosa PAO1
Published 2025-06-01“…However, some of these novel sRNAs have been functionally characterized. In this study, a previously uncharacterized sRNA, LapS, in P. aeruginosa PAO1 was identified as a novel sRNA. …”
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46631
Metabolome and Transcriptome Analysis Reveals the Regulatory Effect of Magnesium Treatment on EGCG Biosynthesis in Tea Shoots (<i>Camellia sinensis</i>)
Published 2025-02-01“…Epigallocatechin-3-O-gallate (EGCG) is an important ingredient that indicates tea quality and has healthcare functions. Magnesium nutrition can improve the quality and yield of tea plants, but its regulatory role in the biosynthesis of EGCG in tea plants has not been clarified. …”
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46632
Identification of SNPs and INDELS associated with duck egg quality traits through a genome-wide association analysis
Published 2024-12-01“…Of the 46 genes, the molecular functions of 22 are related to protein binding, indicating important roles in the formation of egg quality traits. …”
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46633
Metabolomic signatures in liquid biopsy are associated with overall survival in metastatic melanoma patients treated with immune checkpoint inhibitor therapy
Published 2025-04-01“…Enriched functional analysis was conducted to identify the metabolic pathways in which significant metabolites were involved. …”
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46634
Investigating the molecular mechanisms and clinical potential of APO+ endothelial cells associated with PANoptosis in the tumor microenvironment of hepatocellular carcinoma using s...
Published 2025-07-01“…Despite its significance, the specific functions and mechanisms of PANoptosis within the tumor microenvironment (TME) of hepatocellular carcinoma (HCC) remain unclear. …”
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46635
RET inhibition overcomes resistance to combined CDK4/6 inhibitor and endocrine therapy in ER+ breast cancer
Published 2025-01-01“…The functional role of RET was assessed by siRNA-mediated RET silencing and targeted inhibition with the FDA/EMA-approved RET-selective inhibitor selpercatinib in resistant breast cancer cells and patient-derived organoids (PDOs). …”
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46636
Impact of length of stay on diagnostic yield in the epilepsy monitoring unit: A multi‐center retrospective 12‐year Veterans Health Administration study
Published 2025-06-01“…Diagnostic rates were compared between fixed and flexible sites using cumulative distribution functions and other statistical tests. Readmission data for initially inconclusive cases were also examined. …”
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46637
Response‐adapted zanubrutinib and tislelizumab as a potential strategy to enhance CD19 CAR T‐cell therapy in relapsed/refractory large B‐cell lymphoma: A retrospective observationa...
Published 2025-04-01“…DNA sequencing and RNA sequencing were performed on available tumour samples to analyse genetic aberrations and TME characteristics. …”
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46638
Incidence and outcoMes of MInor stroke and high-risk traNsient ischEmic attack in NordicTus. IMMINENT study
Published 2025-07-01“…We recorded clinical, neuroimaging and therapeutic variables. Follow-up was performed at 30 and 90 days. Functional prognosis was assessed with the modified Rankin scale score (mRS). …”
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46639
Cannabidiol as a treatment for patients who are clinically at high risk of developing psychosis: learnings from the CANTOP-RCT
Published 2025-03-01“…In a subsample of participants (total N = 100; n = 50 per treatment arm), we proposed to use magnetic resonance spectroscopy to measure hippocampal glutamate levels, functional magnetic resonance imaging to measure brain activation (while patients performed verbal memory and emotional processing tasks), and arterial spin labelling to measure blood flow to investigate the neurochemical and neurophysiological basis of the effects of cannabidiol (mechanism substudy). …”
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46640
Analysis of the Impact of Effectiveness of Media (Seda-va-Sima) Advertisement on the Extent of Consumers’ Urge to Consume National Commodities
Published 2025-03-01“…Media plays a vital role in advertising, cultural, and supervisory functions by creating a mental framework for accepting the necessity of reform and revising the allocation and distribution of resources and income (Hayek, 2015). …”
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