Generating tumor-specific T cells based on a head and neck cancer organoid for adoptive cell therapy by Yinyu Chen, Yinyu Chen, Shoupeng Wang, Luxi Zheng, Luxi Zheng, Lin Chen, Feng Xu, Shuqi Guo, Shuqi Guo, Jian Meng, Jian Meng, Jian Meng

“…Additionally, this study seeks to explore the cytotoxicity of these T cells against autologous tumor organoids, providing theoretical and experimental evidence for the feasibility of this model as a platform for adoptive cell immunotherapy in head and neck cancer (HNC).MethodsHNCO single cells were co-cultured with peripheral blood lymphocytes (PBLs) collected and isolated from patients with HNC. …”
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The Impact of Infectious Diseases on Clinical Characteristics and Immunological Correlations in Pediatric Henoch–Schönlein Purpura: A Five-Year Retrospective Study by Sînziana Oprițescu, Gabriela Viorela Nițescu, Mihaela Golumbeanu, Dora Boghițoiu, Elena Iuliana Ioniță, Diana-Andreea Ușurelu, Cristian Lucaci, Adriana Negoiță, Elena Moroșan

“…HSP is the most frequent kind of systemic vasculitis in children, characterized by purpura, arthritis or arthralgia, gastrointestinal pain, and kidney dysfunction. …”
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Beta-glucans from biomass of plant and microbial origin by N. Yu. Sharova, B. S. Manzhieva, A. A. Printseva, T. V. Vybornova

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Achievements, priorities and strategies in pediatric nephrology in Europe: need for unifying approaches or acceptance of differences? by Jochen Ehrich, Velibor Tasic, Vidar O. Edvardsson, Evgenia Preka, Larisa Prikhodina, Constantinos J. Stefanidis, Rezan Topaloglu, Diamant Shtiza, Ashot Sarkissian, Thomas Mueller-Sacherer, Rena Fataliyeva, Ina Kazyra, Elena Levtchenko, Danka Pokrajac, Dimitar Roussinov, Danko Milošević, Avraam Elia, Tomas Seeman, Mia Faerch, Inga Vainumae, Janne Kataja, Michel Tsimaratos, Irakli Rtskhiladze, Peter F. Hoyer, George Reusz, Atif Awan, Danny Lotan, Licia Peruzzi, Nazym Nigmatullina, Nasira Beishebaeva, Edite Jeruma, Augustina Jankauskiene, Olivier Niel, Valerie Said-Conti, Angela Ciuntu, Snežana Pavićević, Michiel Oosterveld, Anna Bjerre, Marcin Tkaczyk, Ana Teixeira, Adrian C. Lungu, Alexey Tsygin, Vesna Stojanović, Ludmila Podracka, Tanja Kersnik Levart, Mar Espino-Hernández, Per Brandström, Giuseppina Sparta, Harika Alpay, Dmytro Ivanov, Jan Dudley, Komiljon Khamzaev, Dieter Haffner

“…The aim of this study was to explore the different national approaches to the organization and delivery of pediatric nephrology services within Europe.MethodsIn 2020, the European society for Paediatric Nephrology (ESPN) conducted a cross-sectional survey to identify the existing pediatric nephrology healthcare systems in 48 European countries covering a population of more than 200 million children.ResultsThe reported three most important priorities in the care of children with kidney diseases were better training of staff, more incentives for physicians to reduce staff shortages, and more hospital beds. …”
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Tislelizumab plus concurrent chemoradiotherapy versus concurrent chemoradiotherapy for elderly patients with inoperable locally advanced esophageal squamous cell carcinoma: a multi... by Ke Zhang, Qifeng Wang, Jianzhong Cao, Chengcheng Fan, Wenbin Shen, Qin Xiao, Xiaolin Ge, Tian Zhang, Xiao Liu, Xi Chen, Jie Dong, Zewei Li, Zhunhao Zheng, Cihui Yan, Ping Wang, Qingsong Pang, Wencheng Zhang

“…The main inclusion criteria were pathological confirmation of locally advanced inoperable ESCC at clinical cT1N2-3M0 or cT2-4bN0-3M0 (stage II–IVA), age ≥ 70 years, absence of previous systemic anti-tumor therapy, and adequate organ function. …”
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Does outcome expectancy predict outcomes in online depression prevention? Secondary analysis of randomised‐controlled trials by Janika Thielecke, Paula Kuper, David Ebert, Pim Cuijpers, Filip Smit, Heleen Riper, Dirk Lehr, Claudia Buntrock

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Recent Advancements in Wearable Hydration-Monitoring Technologies: Scoping Review of Sensors, Trends, and Future Directions by Nazim A. Belabbaci, Raphael Anaadumba, Mohammad Arif Ul Alam

“…Despite the potential of wearable devices for continuous hydration monitoring, health research hasn’t fully explored this application, and clear design guidelines are absent. …”
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Cocoa Farmers’ Perceptions of Drought and Adaptive Strategies in the Ghana–Togo Transboundary Cocoa Belt by Afi Amen Christèle Attiogbé, Udo Nehren, Emmanuel Quansah, Enoch Bessah, Seyni Salack, Jean Mianikpo Sogbedji, Sampson K. Agodzo

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X-Ray Polarization Variability during a Few Hz Quasiperiodic Oscillations in Swift J1727.8-1613 Observed with IXPE by Kaito Ninoyu, Shinya Yamada, Yuusuke Uchida, Taichi Igarashi, Ryota Hayakawa, Takayoshi Kohmura

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Comprehensive Review of Alternative Proteins in Pet Food: Research Publications, Patents, and Product Trends in Plant, Aquatic, Insect, and Cell-Based Sources by Phatthranit Klinmalai, Pitiya Kamonpatana, Arisara Thongpech, Janenutch Sodsai, Khwanchat Promhuad, Atcharawan Srisa, Yeyen Laorenza, Attawit Kovitvadhi, Sathita Areerat, Anusorn Seubsai, Shyam S. Sablani, Nathdanai Harnkarnsujarit

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Relationships between measures of neurovascular integrity and fluid transport in aging: a multi-modal neuroimaging study by Ella Rowsthorn, Lachlan Cribb, Benjamin Sinclair, William Pham, Trevor T.-J. Chong, Stephanie Yiallourou, Marina Cavuoto, Lucy Vivash, Terence J. O’Brien, Xingfeng Shao, Danny J. J. Wang, Meng Law, Matthew P. Pase, Ian H. Harding

“…Abstract Fluid transport in the neurovascular unit is essential for maintaining brain health through nutrient delivery and waste clearance. However, these systems are complex and the inter-dependencies between elements of these systems and how they may change through aging is not well understood. …”
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Investigating the effects of global gene knockout of MrgF on motor performance and pain sensitivity in mice by Xuejiao Chen, Yan Chen, Runzhe Shu, Shunyuan Lu, Ming-Min Gu, Chunling Shen, Zhugang Wang, Xiaofang Cui

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Multi-scale coupling quantitative assessment of ecological-urban resilience in the Yangtze River Economic Belt by Jinyang Wang, Zhenfeng Shao, Qingwei Zhuang, Chaoya Dang, Peiqing Jing, Bowen Cai, Siyuan Wang, Jun Li, Fei Yang, Wei Wang, Neema Simon Sumari, Walter Musakwa

“…Current research has not yet explored the spatial and temporal patterns of the coupling relationship between urban and ecological systems at the county scale. …”
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Efficacy of toripalimab in combination with anlotinib in recurrent undifferentiated pleomorphic sarcoma of the sinonasal region: a case report with biomarker analysis by Fang Wu, Junqiao Feng, Hong Wang, Shan Wang, Xiaoguang Cui, Ying Liu, Linli Yan, Kaihong Ye, Rick F. Thorne, Xu Dong Zhang, Ting La

“…Genotyping and immunohistochemistry revealed that the sarcoma cells were rapidly dividing and enriched in vasculature prior to systemic treatment.ConclusionThese findings suggest that the combination of toripalimab and anlotinib may be an effective treatment option for advanced cases of UPS in the sinonasal region.…”
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Induction of tissue resident memory T cells by measles vaccine vector by Heidy Vera-Peralta, Claude Ruffié, Valérie Najburg, Matthias Brione, Chantal Combredet, Phanramphoei Frantz, Jean-Nicolas Tournier, Frédéric Tangy, Marie Mura

“…Measles live attenuated vaccine (MV) induces strong humoral and cellular systemic memory responses allowing the successful control of measles since decades. …”
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Comparative analysis of Opuntia ficus-indica mucilage and gum arabic as wall materials in anthocyanin-rich raspberry pomace microencapsulation for potential food packaging applicat... by NP Mbonambi, F Seke, OA Fawole

“…The encapsulated powders were evaluated for physicochemical, functional, and antimicrobial properties to determine their suitability for food packaging applications. …”
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<em>Voacanga globosa</em> Spirobisindole Alkaloids Exert Antiviral Activity in HIV Latently Infected Cell Lines by Targeting the NF-κB Cascade: In Vitro and In Silico Investigation... by Ma. Sheila M. de Jesus, Allan Patrick G. Macabeo, John Donnie A. Ramos, Von Novi O. de Leon, Kaori Asamitsu, Takashi Okamoto

“…Alkaloids <b>1</b>–<b>3</b> were explored for their inhibitory activity on TNF-α-induced viral replication in two latently HIV-infected cell lines, OM10.1 and J-Lat. …”
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Interaction effects in microbiota-filter media-pharmaceutical in biofilm-based reactors: a case study of anoxic biofilters by Rui Ma, Han Zhao, Ying Zhao, Lili Jin, Hui Huang, Hongqiang Ren

“…The removal of micropollutants, particularly pharmaceuticals, from wastewater remains a significant challenge due to their persistence and complex degradation mechanisms. Biofilm-based systems offer a promising solution due to their high microbial diversity and metabolic versatility. …”
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Evaluating the impact of deep learning approaches on solar and photovoltaic power forecasting: A systematic review by Oussama Khouili, Mohamed Hanine, Mohamed Louzazni, Miguel Angel López Flores, Eduardo García Villena, Imran Ashraf

“…Accurate solar and photovoltaic (PV) power forecasting is essential for optimizing grid integration, managing energy storage, and maximizing the efficiency of solar power systems. Deep learning (DL) models have shown promise in this area due to their ability to learn complex, non-linear relationships within large datasets. …”
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Once a Triple, Not Always a Triple: The Evolution of Hierarchical Triples That Yield Merged Inner Binaries by Cheyanne Shariat, Smadar Naoz, Kareem El-Badry, Antonio C. Rodriguez, Bradley M. S. Hansen, Isabel Angelo, Alexander P. Stephan

“…Our findings indicate that in 26%–54% of wide double white dwarf (DWD) binaries ( s ≳ 100 au), the more massive white dwarf (WD) is a merger product, implying that these DWD binaries were previously triples. Overall, we estimate that 44% ± 14% of observed wide DWDs originated in triple star systems and thereby have rich dynamical histories. …”
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