Effect of Dinalbuphine sebacate on postoperative multimodal analgesic strategy in video-assisted thoracoscopic surgery: a double-blind randomized controlled trial by Hung-Te Hsu, Chao-Wei Ma, Po-Chih Chang, Yi-Wei Kuo, Tz-Ping Gau, Yu-Wei Liu, Yen-Chin Liu, Shah-Hwa Chou, Kuang-I Cheng

“…The aim of this study is to evaluate the effectiveness of DS in MMA for video-assisted thoracoscopic surgery (VATS). Methods Sixty participants were randomly and equally assigned to either the MMA regimen containing DS (DS group) or placebo (placebo group). …”
Get full text

Comparison of 68Ga-DOTATATE and 18F-FDG PET/CT for tumor staging and primary tumor volume delineation in patients with nasopharyngeal carcinoma by Haoyuan Ding, Juan Liang, Yudi Wang, Kaixiang He, Lin Liu, Ya Liu, Yue Chen

“…Among the methods, THbgd for lesion segmentation in 68Ga-DOTATATE PET demonstrated the highest confidence level and concordance with MRI (ICC 0.95). …”
Get full text

Comparison the Influence of Various Intensities of Aerobic Training on the Expression of RBL-1 and RB1 Genes in the Subcutaneous Adipose Tissue of Male Wistar Rats by Maryam Shavandi, Saeid Naghibi, Mohammad Shariatzadeh Joneydi, Maryam Vatandoust, Ali Zare

“…Since the expression of adipogenic genes such as Retinoblastoma-1 (RB1) and Retinoblastoma like-1 (RBL-1) proteins are effective in adipogenesis, the aim of this study was to investigate the influence of various intensities of aerobic training on the expression of RB1 and RBL-1 genes in the subcutaneous adipose tissue of male Wistar rats.Materials and Methods: In this experimental study, 32 male Wistar rats (eight weeks old and weight: 237 ± 33 grams) were randomly divided into four equal groups: control, high intensity training (HIT), Moderate-intensity training (MIT) and high-intensity interval training (HIIT). …”
Get full text

Aryana-bs: context-aware alignment of bisulfite-sequencing reads by Hassan Nikaein, Ali Sharifi-Zarchi, Afsoon Afzal, Saeedeh Ezzati, Farzane Rasti, Hamidreza Chitsaz, Govindarajan Kunde-Ramamoorthy

“…To address this challenge, two alignment methods have been well established: three-letter alignment and wildcard alignment. …”
Get full text

Investigating the relationship between personal values and green consumption in students of Shahid Beheshti University by Azadeh Askari, Sepideh Samaee

“…The convenience sampling method was used for sampling. According to the sample size table, 375 people were selected and 353 questionnaires were analyzed. …”
Get full text

The effect of a period of resistance training on Thrombosponidine-1 and Follistatin-like-1 in heart tissue of obese male rats by Neda Ghasemi, Mania Roozbayani, Hossein Shirvani

“…The aim of this study was to investigate the changes in thrombospondin-1 and follistatin-like factor-1 of heart tissue following six weeks of resistance training in obese male rats. Materials and Methods: In an experimental study, 20 male Wistar rats were divided into two equal groups of control and experimental based on their body weight. …”
Get full text

Influence of chronic prenatal hypoxia on the specialized contact apparatus of rat heart ventricles during ontogeny by N. S. Petruk

“…Morphometric and statistical methods were applied. Pairwise comparisons between means of different groups were performed using Student’s t-test where, for each couple of normally distributed populations, the null hypothesis that the means are equal was verified. …”
Get full text

Quantitative and qualitative investigation of shunt failure in an in vitro hemorrhagic hydrocephalus model by Shaheer Ajaz, Ahmad Faryami, Ayman Suhrawardy, Carolyn A. Harris

“…Using the Automated, In Vitro Model for Hydrocephalus Research (AIMS), we investigated the impact of CSF-like diluted blood solution on ventricular catheters and external ventricular drains (EVD) using quantitative (flow and pressure measurements) and qualitative (real-time brightfield video capture) methods.MethodsThe shunt failure criteria were set at greater than or equal to 30 cmH2O such that the experiment was manually terminated if pressure surpassed 30 cmH2O differential pressure at any point within 24 h. …”
Get full text

Construction of a Novel Necroptosis-Related Signature in Rat DRG for Neuropathic Pain by Liu Y, Hao S, Hao H, Zheng G, Bing J, Kang L, Li J, Zhao H, Hao H

“…This study aims to identify a gene signature related to necroptosis in DRG that can predict neuropathic pain.Methods: The mRNA expression profiles associated with neuropathic pain (GSE24982 and GSE30691) were acquired from the Gene Expression Omnibus (GEO) database. …”
Get full text

Muscone Ameliorates High-Altitude Hypoxia Gastrointestinal Stress via Modulation of Lactobacillus Murinus and Mitochondrial Metabolism by Zeng J, Yin X, Pang Y, Zhang J, Xie C, Chen S, Zhang L, Li X, Pan Y, An J

“…The ameliorative effects of Lactobacillus murinus on acute gastrointestinal stress induced by high-altitude conditions were validated through various methods, such as HE staining, immunohistochemistry, transmission electron microscopy, ELISA, and flow cytometry. …”
Get full text

Cost-effectiveness of Procalcitonin (PCT) guidance for antibiotics management of adult sepsis patients in the Egyptian context by Mohamed Metwally Mosly, Hesham Metwalli Mousli, Iman Mohamed Momtaz Ahmed, Mohamed Ibrahim Affify Abdou

“…The CEAC showed a slightly higher probability in terms of acceptability in favor of the no PCT guidance choice along the WTP scale till reaching equal probabilities at the willingness-to-pay (WTP) value point of 390,000 (state currency) after which the - probability supports the PCT guidance choice. …”
Get full text

Using Machine Learning to Predict Linezolid-Associated Thrombocytopenia by Wei R, Li K, Wang H, Cai X, Liu N, An Z, Zhou H

“…Rao Wei,1,* Kexin Li,1,* Huaguang Wang,1 Xinbo Cai,1 Nian Liu,2 Zhuoling An,1 Hong Zhou1 1Pharmacy Department of Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Hematology Department of Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhuoling An, Pharmacy Department of Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China, Email anzhuoling@163.com Hong Zhou, Pharmacy Department of Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China, Email Zhhz0513@163.comObjective: Using artificial intelligence and machine learning to predict linezolid-induced thrombocytopenia helps identify related risk factors in patients.Methods: Between January 2020 and December 2023, 284 patients receiving linezolid from Beijing Chaoyang Hospital were enrolled. …”
Get full text

Clinical-epidemiological characteristics delivery cases of tropic dengue fever by V. V. Nechaev, I. I. Yarovaya, G. V. Kachenya, E. V. Doguzhieva, S. S. Buntovskya, A. D. Egorickhina, R. S. Shkurskaya, I. G. Chkhindzeria, N. E. Chunaeva

“…Petersburg.Materials and methods. The obtained data of official registration of cases of diseases in the Department of accounting and registration of infectious and parasitic diseases of the city of St. …”
Get full text

Analysis of production and financial potential as a basis for developing a strategy for modernizing the Russian economy by Ljudmila I. Rozanova, Sergei V. Tishkov

“…The functioning institutions of the financial market also do not ensure equal access to credit resources for small and medium-sized businesses.The scientific novelty of this study is that the authors identified the main problems of the process of modernization and implementation of innovative developments in the context of high levels of depreciation of production systems and inadequate investment resources. …”
Get full text

Prediction Model for Brain Metastasis in Patients With Metastatic Germ‐Cell Tumors by Tareq Salous, Ryan Ashkar, Sandra K. Althouse, Clint Cary, Timothy Masterson, Nasser H. Hanna, Jennifer King, Lawrence H. Einhorn, Nabil Adra

“…We aimed to establish an effective and practical BM prediction model. Patients and Methods Between January 1990 and September 2017, 2291 patients with mGCT who were treated at Indiana University were identified. …”
Get full text

Phytotea “ATINE” has beneficial effects on some neural, endocrine, immune, metabolic and biophysics variables in patients with maladaptation by Igor Bombushkar, Anatoliy Gozhenko, Ivan Savytskyi, Dariya Popovych, Nataliya Badiuk, Anatoliy Anchev, Viktor Duzhar, Igor Popovych

“…The parameters of metabolism, EEG, HRV, acupuncture, biophotonics, cholekinetics, immunity, microbiota as well as adaptation hormones was assessed using routine methods, and two equal groups were formed on this basis. …”
Get full text

Empagliflozin-Pretreated MSC-Derived Exosomes Enhance Angiogenesis and Wound Healing via PTEN/AKT/VEGF Pathway by Wang H, Bai Z, Qiu Y, Kou J, Zhu Y, Tan Q, Chen C, Mo R

“…Current treatment methods are limited and often ineffective in promoting wound repair. …”
Get full text

Exploring the Potential of Chaihu-Danggui Tang in Breast Cancer Treatment Based on Network Pharmacology, Molecular Docking, and Experimental Validation by Liu Y, Zhang J, Lai Y, Wu C, Liu D, Liang R, Chen G, Jiang X

“…In this study, we used network pharmacology, molecular docking, and experimental validation methods to investigate the core components, key targets, and possible mechanisms through which CHDGT may exert therapeutic effects in BC treatment.Methods: The Traditional Chinese Medicine Systems Pharmacology (TCMSP) was employed to obtain the active ingredient and targets of CHDGT. …”
Get full text

Assessing the Causal Relationship between Chronic Obstructive Pulmonary Disease and Tuberculosis: A Mendelian Randomization Study by Wang Z, Zhao S, Zhou Y, He Y

“…However, their causal relationship remains unclear.Methods: We utilized genome-wide association study (GWAS) datasets to conduct bidirectional two-sample Mendelian randomization and multivariable Mendelian randomization analyses. …”
Get full text

NDVI estimation using Sentinel-1 data over wheat fields in a semiarid Mediterranean region by Emna Ayari, Zeineb Kassouk, Zohra Lili-Chabaane, Nadia Ouaadi, Nicolas Baghdadi, Mehrez Zribi

“…The use of RF and SVR outperformed the curve-fitting methods with an RMSE equal to 0.12. The present findings revealed the high accuracy of the proposed approach to estimate the missing values of wheat fields NDVI values during the vegetation development period until heading and the senescence phase. …”
Get full text