A dual-reporter LDLR system integrating fluorescence and luminescence for understanding LDLR regulation and facilitating drug discovery by Peng Jiao, Peng Jiao, Peng Jiao, Peng Jiao, Na Yang, Na Yang, Qianfeng Jia, Baozhen Fan, Ke Feng, Ke Feng, Jian Yu, Shengtian Zhao, Shengtian Zhao, Shengtian Zhao

“…The dual-reporter system allows real-time visualization of LDLR expression via EGFP fluorescence and quantitative assessment through secreted Gluc activity. …”
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Harnessing artificial intelligence to revolutionize vocational education: Emerging trends, challenges, and contributions to SDGs 2030 by Febri Prasetya, Aprilla Fortuna, Agariadne Dwinggo Samala, Dinda Khaira Latifa, Welli Andriani, Utari Akhir Gusti, Muhammad Raihan, Santiago Criollo-C, Deniz Kaya, Juan Luis Cabanillas García

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Integrated analyses and a novel nomogram for the prediction of significant fibrosis in patients by Mengxin Lu, Shuai Tao, Xinyan Li, Qunling Yang, Cong Du, Weijia Lin, Shuangshuang Sun, Conglin Zhao, Neng Wang, Qiankun Hu, Yuxian Huang, Qiang Li, Yi Zhang, Liang Chen

“…Introduction and Objectives: This study aimed to explore the key genes involved in the pathophysiological process of liver fibrosis and develop a novel predictive model for noninvasive assessment of significant liver fibrosis patients. Patients and Methods: Differentially expressed genes (DEGs) were identified using the Limma package. …”
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Clinician Perspectives of a Magnetic Resonance Imaging–Based 3D Volumetric Analysis Tool for Neurofibromatosis Type 2–Related Schwannomatosis: Qualitative Pilot Study by Shelby T Desroches, Alice Huang, Rithvik Ghankot, Steven M Tommasini, Daniel H Wiznia, Frank D Buono

“…ObjectiveThe objective of the study was to survey and interview clinicians treating neurofibromatosis type 2–related schwannomatosis to understand their views on current 2D analysis and to gather insights for the design of an artificial intelligence–driven 3D volumetric analysis tool. MethodsInterviews examined for the following themes: (1) shortcomings of the currently used linear analysis, (2) utility of 3D visualizations, (3) features of an interactive 3D modeling software, and (4) lack of a gold standard to assess the accuracy of 3D volumetric analysis. …”
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Research hotspots and trends on NF-κB in cognitive impairment: a bibliometric analysis by Lin Bai, Lin Bai, Fangyuan Xu, Peijia Hu, Peijia Hu, Zhiqiang Shen, Zhiqiang Shen, Su Xingxing, Su Xingxing, Qingqing Wang, Qingqing Wang, Hongliang Cheng, Hongliang Cheng

“…Gut microbiota and ketogenic diet also play an important role in NF-κB in CI.ConclusionThis bibliometric analysis and visualization using VOSviewer and CiteSpace revealed that the role of NF-κB in CI has become a research hotspot. …”
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Use of Robotic Surgery for the Management of Orbital Diseases: A Comprehensive Review by Riccardo Nocini, Lorenzo Marini, Luca Michelutti, Chiara Zilio, Stefania Troise, Salvatore Sembronio, Giovanni Dell’Aversana Orabona, Massimo Robiony, Alessandro Tel

“…This review explores the use of robotic surgery in orbital pathology, focusing on its applications, benefits, and limitations. <i>Materials and Methods</i>: A cross-sectional search method was performed in multiple databases to answer the following question: “What are the applications of robotic surgery in the management of orbital pathologies?” …”
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Automatic segmentation model and machine learning model grounded in ultrasound radiomics for distinguishing between low malignant risk and intermediate-high malignant risk of adnex... by Lu Liu, Wenjun Cai, Feibo Zheng, Hongyan Tian, Yanping Li, Ting Wang, Xiaonan Chen, Wenjing Zhu

“…We used SHapley Additive exPlanations to interpret and visualize the model. Graphical Abstract…”
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Clinical experience of cone-beam computed tomography in interventional neuroradiology by D.V. Shchehlov, S.V. Chebanyuk, O.E. Svyrydiuk, S.V. Konotopchyk, O.F. Sydorenko, V.R. Pankiv, M.B. Vyval

“…CBCT is useful for understanding vascular anatomy and allows for more detailed visualization of the curvilinear course of vessels in 3D space along any plane with the possibility of their correlation with bone structures compared to traditional angiography, and also has a higher resolution compared to more common 3D digital subtraction angiography. …”
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A bioinformatic analysis to systematically unveil shared pathways and molecular mechanisms underlying monkeypox and its predominant neurological manifestations by Amir Hossein Barjasteh, Hanieh Latifi, Ali Sepehrinezhad, Ali Sepehrinezhad

“…This study aimed to explore the genetic underpinnings of MPOX-related neurological manifestations, including headache, myalgia, fatigue, and photophobia, using advanced bioinformatics tools.MethodsData were sourced from the GeneCards database, which is an integrated database of human genes. …”
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Novel computational One-Health analysis of fibrinogen-binding protein A in Streptococcus agalactiae Isolated from fish and human cases by Rifaldi Iqbal Yadiansyah, Endang Linirin Widiastuti, Wawan Abdullah Setiawan, Favorisen Rosyking Lumbanraja, Rifky Rizkiantino

“…Residue profiling and structural visualization were conducted in PyMOL. Molecular docking between FbsA and Aα (G), Bβ (H), and γ (I) chains of human Fg was performed using ClusPro, followed by interaction analysis using LigPlot+. …”
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Insulin-induced lipohypertrophy: clinical and ultrasound characteristics by Vadim V. Klimontov, Mikhail M. Lazarev, Alexey A. Makhotin, Andrey Ju. Letyagin, Lilia A. Anisimova, Dinara M. Bulumbaeva, Elena A. Koroleva, Alexander P. Lykov

“…Ultrasonography is more sensitive method of diagnostics of lipohypertrophy compared with palpation. …”
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Development of an RT-LAMP Assay for Detecting <i>tet</i>(M) in <i>Enterococcus</i> Species: Enhancing AMR Surveillance Within the One Health Sectors by Ebthag A. M. Mussa, Anis Rageh Al-Maleki, Musheer A. Aljaberi, Abdulsamad Alsalahi, Mohd Nasir Mohd Desa, Azmiza Syawani Jasni, Siti Zubaidah Ramanoon, Atiyeh M. Abdallah, Rukman Awang Hamat

“…The sigmoidal graphs were corroborated with visual confirmation methods, including a green color change (visible to the naked eye), green fluorescence (under UV light), and a 200 bp PCR product observed via agarose gel electrophoresis. …”
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Telomeric RNA quadruplexes as targets for cancer prevention: The therapeutic potential of agonodepsides by Gourav Choudhir, Sushil Kumar, Mohammad Shahid, Anas Shamsi, Asimul Islam

“…Discovery Studio software was utilized for the visualization of interactions between ligands and TERRA G4. …”
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Diff-Tree: A Diffusion Model for Diversified Tree Point Cloud Generation with High Realism by Haifeng Xu, Yongjian Huai, Xiaoying Nie, Qingkuo Meng, Xun Zhao, Xuanda Pei, Hao Lu

“…Three-dimensional (3D) virtual trees play a vital role in modern forestry research, enabling the visualization of forest structures and supporting diverse simulations, including radiation transfer, climate change impacts, and dynamic forest management. …”
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Utility of a Large Series of B‐Cell Precursor Acute Lymphoblastic Leukemia Cell Lines as a Model System by Minori Tamai, Chiaki Komatsu, Keiko Kagami, Shin Kasai, Koshi Akahane, Kumiko Goi, Kanji Sugita, Chihiro Tomoyasu, Toshihiko Imamura, Hiroaki Goto, Takeshi Inukai

“…Results In the UMAP visualization, a close association was confirmed between the types of fusion genes and patterns of gene expression. …”
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Comparing 1-L and 2-L Polyethylene Glycol with Ascorbic Acid for Small Bowel Capsule Endoscopy: A Randomized Controlled Trial by Chang Kyo Oh, Sang Pyo Lee, Jae Gon Lee, Young Joo Yang, Seung In Seo, Chang Seok Bang, Yu Jin Kim, Woon Geon Shin, Jin Bae Kim, Hyun Joo Jang, Sea Hyub Kae, Gwang Ho Baik, Hallym Gastrointestinal Study Group

“…One liter-PEG with AA can be recommended as the standard method for bowel cleansing for SBCE.…”
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The alteration of the sensorimotor network in trigeminal neuralgia after microvascular decompression surgery: a follow-up study using independent component analysis by Yan Zhang, Yan Zhang, Xueju Wang, Xuefeng Wang, Gengdi Huang

“…Recent advances in neuroimaging have enhanced visualization of the trigeminal nerve’s vascular anatomy, deepening insights into TN pathophysiology and paving the way for improved diagnostics and therapies. …”
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Enhanced clinical photoacoustic vascular imaging through a skin localization network and adaptive weighting by Chuqin Huang, Emily Zheng, Wenhan Zheng, Huijuan Zhang, Yanda Cheng, Xiaoyu Zhang, Varun Shijo, Robert W. Bing, Isabel Komornicki, Linda M. Harris, Ermelinda Bonaccio, Kazuaki Takabe, Emma Zhang, Wenyao Xu, Jun Xia

“…Despite its promising capabilities to provide high-resolution images, the visualization of vessels might be hampered by skin signals and attenuation in tissues. …”
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Delta large-channel endoscopy versus unilateral biportal endoscopy decompressive laminectomy for lumbar spinal stenosis: a prospective randomized controlled trial by Rushuo Wei, Weiqiang Liu, Mingdong Yu, Yushan Zhu, Ruzhan Yao, Bingwu Wang, Jesse Li-Ling

“…This randomized controlled trial aims to compare their perioperative outcomes, focusing on postoperative recovery and complications over time. Methods In total, 101 participants were randomly assigned to Delta large-channel endoscopy group (n = 50) or UBE group (n = 51). …”
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Optimizing Contrast‐Enhanced Magnetic Resonance Neurography of the Brachial Plexus With Delayed Scanning by Jun Xu, Xiaoli Hu, Xiaoyun Su, Shen Gui, Ziqiao Lei, Xiaoming Liu, Xiangzhi Zhou, Lixia Wang, Wenjun Wu, Xiangchuang Kong

“…Methods Fifteen patients underwent brachial plexus imaging using the 3D T2‐NerveView sequence with a scanning duration of 5 min. …”
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