A single-institution experience with intraoperative in vivo confocal laser endomicroscopy for brain tumors in 50 patients by Yuan Xu, Thomas J. On, Irakliy Abramov, Oscar Alcantar-Garibay, Joelle N. Hartke, Jennifer M. Eschbacher, Kivanc Yangi, Michael T. Lawton, Kris A. Smith, Randall W. Porter, Mark C. Preul

“…We evaluated the feasibility and diagnostic capability of the first clinically approved CLE system for intraoperative in vivo imaging of brain tumors.MethodsA total of 50 patients who were to undergo brain tumor surgery were prospectively enrolled. …”
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Mediation Analyses Link Cardiometabolic Factors and Liver Fat With White Matter Hyperintensities and Cognitive Performance: A UK Biobank Study by Daniel E. Askeland-Gjerde, Lars T. Westlye, Patrik Andersson, Max Korbmacher, Ann-Marie de Lange, Dennis van der Meer, Olav B. Smeland, Sigrun Halvorsen, Ole A. Andreassen, Tiril P. Gurholt

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Impact of enrichment medium on PCR-based detection of Listeria monocytogenes in food by Barbara JERŠEK, Tamara MAJSTOROVIĆ, Nataša KLUN, Sonja SMOLE MOŽINA

“…Comparative evaluation of different enrichment media for bacteria of the genus Listeria (half Fraser - HF, buffered peptone water - BPW, triptic soy yeast extract broth -  TSBYE, universal preenrichment broth - UPB) showed that only the UPB enabled detection of L. monocytogenes in artificially contaminated food samples after 24h of incubation. The PCR-based method gave equal results as standard cultural method by analysis of naturally contaminated food samples. …”
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-Plot for Testing Spherical Symmetry for High-Dimensional Data with a Small Sample Size by Jiajuan Liang

“…The new graphical method associated with the local acceptance regions can provide a quick visual perception on the assumption of spherical symmetry. …”
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Green first derivative synchronous spectrofluorimetric determination of lacidipine and its acid degradation product in plasma and mixtures by Khalid A.M. Attia, Mohamed A. Hasan, Abdalla M. El-Shanawany

“…Peak amplitude of the first derivative synchronous was measured at 409 nm by using constant wavelength difference (Δλ = λem - λex = costant) which equal 160 nm. The regression plot of the proposed first derivative synchronous spectrofluorimetric method was found to be linear over the range of 50–300 ng/mL with a determination coefficient equals 0.9997, limit of detection (LOD) was 14.51 ng/mL but limit of quantification (LOQ) was 43.97 ng/mL.…”
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A Fluorescence-Based Genetic Screen to Study Retinal Degeneration in Drosophila. by Yu Huang, Jun Xie, Tao Wang

“…The Drosophila visual system has been proved to be a powerful genetic model to study eye disease such as retinal degeneration. …”
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Antitumor effect of a new human epidermal growth factor receptor inhibitor by O. I. Kit, I. P. Kodonidi, E. M. Frantsiyants, I. V. Kaplieva, A. A. Glushko, L. K. Trepitaki, E. I. Surikova, V. A. Bandovkina, Yu. A. Pogorelova, I. V. Neskubina, O. V. Bykadorova, E. V. Serdyukova

“…Preclinical study in experiment of antitumor efficacy of a new substance synthesized on the basis of pyrimidin-4-one derivative.Materials and methods. The sodium salt of 4-{2-[2-[2-(4-hydroxy-3-methoxyphenyl)-vinyl]-6-ethyl-4-oxo-5-phenyl-4H-pyrimidin-1-yl}-benzsulfamide, a new inhibitor of the internal domain of the epidermal growth factor receptor (EGFR), was used in this study. …”
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Unraveling the mitochondrial genome of the medicinal Chinese motherwort (Leonurus japonicus, Lamiaceae): structural dynamics, organelle-to-nuclear gene transfer, and evolutionary i... by Xinyu Bai, Xinyu Bai, Tingting Zhu, Huiru Chen, Xiaoqun Wang, Jing Liu, Yuqing Feng, Yuqing Feng, Yanbo Huang, Joongku Lee, Goro Kokubugata, Zhechen Qi, Xiaoling Yan

“…Elucidating mitogenomic structure and evolution can inform plant genetics, phylogenetics, and molecular breeding.MethodsWe assembled the complete mitochondrial genome of L. japonicus using a combination of Oxford Nanopore long reads and Illumina short reads. …”
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Feasibility of magnetic resonance imaging-guided cardiac catheterization, angioplasty, and stenting in a commercial wide-bore 0.55T scanner by Aimee K. Armstrong, Yixuan Liu, John M. Kelly, Ramkumar Krishnamurthy, Jason Swinning, Yingmin Liu, Matthew Joseph, Ning Jin, Jianing Pang, Florian Maier, Axel J. Krafft, Orville Bramwell, Nathan Ooms, Jesse Roll, Joshua Krieger, David C. Gross, Lucien de Mos, Paul Borm, Orlando P. Simonetti

“…A secondary aim was to evaluate three different sizes of magnetic resonance (MR)-visible markers. Methods: Sheaths were placed in the femoral vein and artery of juvenile Yorkshire pigs under general anesthesia. …”
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Region Segmentation of Images Based on a Raster-Scan Paradigm by Luka Lukač, Andrej Nerat, Damjan Strnad, Štefan Horvat, Borut Žalik

“…Furthermore, a comparison with two of the well-known segmentation methods—Watershed and DBSCAN—demonstrates that the proposed approach is superior in regard to efficiency while yielding visually similar results.…”
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Ultraviolet laser induced periodic surface structures positively influence osteogenic activity on titanium alloys by Luiz Schweitzer, Luiz Schweitzer, Janosch Schoon, Niklas Bläß, Katrin Huesker, Janine V. Neufend, Nikolai Siemens, Sander Bekeschus, Sander Bekeschus, Rabea Schlüter, Peter Schneider, Eckart Uhlmann, Eckart Uhlmann, Georgi Wassilew, Frank Schulze

“…Scanning electron microscopy was used for visualization of surface topography and adherent cells. …”
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Co-Designing a Web-Based and Tablet App to Evaluate Clinical Outcomes of Early Psychosis Service Users in a Learning Health Care Network: User-Centered Design Workshop and Pilot St... by Kathleen E Burch, Valerie L Tryon, Katherine M Pierce, Laura M Tully, Sabrina Ereshefsky, Mark Savill, Leigh Smith, Adam B Wilcox, Christopher Komei Hakusui, Viviana E Padilla, Amanda P McNamara, Merissa Kado-Walton, Andrew J Padovani, Chelyah Miller, Madison J Miles, Nitasha Sharma, Khanh Linh H Nguyen, Yi Zhang, Tara A Niendam

“…MethodsOur UCD approach included incorporation of user feedback, prototyping, iterative design, and continuous evaluation. …”
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Cell death pathway regulation by fatty acid metabolism-related genes in neuroblastoma: a multi-omics analysis identifying CHD5 as a novel biomarker by Yankun Chen, Junzhi Liu, Yubin Jia, Jiaxing Yang, Yan Jin, Yun Liu, Benfu Zhong, Qiang Zhao

“…While dysregulated cell death mechanisms and metabolic reprogramming are hallmarks of cancer progression, the interplay between fatty acid metabolism and cell death pathway regulation in neuroblastoma remains incompletely understood. Methods Identifying molecular subtypes influenced by fatty acid metabolism were built by consensus clustering analysis. …”
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Comparison of endoscopic and microscopic microvascular decompression for treating primary trigeminal neuralgia by Lei Li, Lei Li, Dongqi Shao, Xialin Zheng, Yuanbo Pan, Tao Sun, Huadong Tang, Hongjie Zhai, Xiaohui Dong, Jing Sun, Mengtian Fang, Feiyun Lou, Zhiquan Jiang, Zhiquan Jiang

“…ObjectiveTo compare the intraoperative outcome and postoperative efficacy of endoscopic and microscopic microvascular decompression (MVD) under neuroelectrophysiological monitoring in the treatment of primary trigeminal neuralgia (PTN).MethodsThis retrospective study included 131 patients with PTN who were admitted to our hospital between January 2019 and October 2022. …”
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The Role of the Educational Programs in the Improving of Confidence in Vaccination against Pneumococcal Infection among Population by N I Briko, V A Korshunov, A Ya Mindlina, R V Polibin, A V Shamis, A G Saltykova

“…Statistical processing was performed using IBM SPSS Statistics v.20.0, data visualization – Microsoft Excel 2016. Results. The proportion of students who have a positive attitude towards vaccination increased by 16% – from 41.0±5.6% to 57.0±6.0%, p<0.05. …”
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Percutaneous Lapidus Procedure for the Management of Primary Hallux Valgus Deformity – A Retrospective Cohort Analysis by Alasdair John Henry Barrie MBChB MSc FRCS, James Ryeburn BSc, Alastair S.E. Younger MB ChB, ChM, FRCSC, Andrea Veljkovic MD, MPH, BComm, FRCSC, Kevin Wing MD, FRCSC, Murray J. Penner MD, FRCSC, Oliver Gagne MD, FRCSC

“…Our technique entails percutaneous preparation of the first tarsometatarsal joint using a Shannon burr for debridement, arthroscopy for visualization, and fixation with three full thread 4 mm non-variable pitch headless chamfered cannulated screws, preserving subchondral bone for stability. …”
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Distribution Patterns and Driving Factors of Highly Educated Talent in China from a Heterogeneity Perspective: An Examination Based on Prefectural Administrative Regions by Wu Rongwei, Wang Yuanxin, Zhang Qin, Zhou Liang

“…We employed the Gini coefficient and visualization methods to depict the spatiotemporal patterns of talent distribution at college, undergraduate, and graduate education levels in Chinese prefecture-level administrative regions. …”
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Application of augmented reality technology in the surgery of skull base tumor and cerebrovascular disease by GUO Yi⁃ding, ZHAO Ben⁃qi, ZHANG Pei⁃hai, LIU Yong, CHEN Gang, YANG Xue⁃jun, GUO Yi

“…The feasibility and applicability of AR assisted technology is currently the most important topic in clinical research. Methods Four cases engaged from January to December 2024 in Department of Neurosurgery of Beijing Tsinghua Changgung Hospital with vestibular schwannoma (one case), intracranial aneurysm (2 cases) and subclavian artery (SA) occlusion caused vertebral artery steal syndrome (one case) have been conducted tumor resection, internal carotid artery (ICA)⁃posterior communicating artery (PCoA) aneurysm clipping and common carotid artery (CCA)⁃SA bypass, respectively. …”
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Extended Trochanteric Osteotomy Increases the Risk of Tapered Splined Stem Subsidence in Revision Total Hip Arthroplasty by Josef E. Jolissaint, MD, Samuel Rodriguez, MD, Leonardo Albertini Sanchez, BA, Travis R. Weiner, BS, Elizabeth B. Gausden, MD, MPH, Jason L. Blevins, MD, Peter Sculco, MD, Jose Rodriguez, MD, FAOA

“…An extended trochanteric osteotomy is an excellent technique to gain direct visualization of the femoral canal. However, it is not without its associated morbidity and postoperative complications, specifically stem subsidence. …”
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Algorithm for the provision of comprehensive psychotherapeutic support to women experiencing neuropsychiatric symptoms during rehabilitation following the treatment of malignant ne... by D. V. Blinov, A. G. Solopova, E. E. Achkasov, E. S. Akarachkova, O. V. Kotova, S. A. Akavova, V. N. Galkin, G. K. Bykovshchenko, L. N. Sandzhieva, D. I. Korabelnikov, T. A. Blbulyan, D. A. Petrenko, A. Yu. Vlasina

“…Chronic pain syndrome, distress, anxiety and depression, decreased self-esteem, sexual dysfunction and social maladjustment reduce quality of life (QoL) and require psychotherapeutic support.Objective: to create an algorithm for the provision of comprehensive psychotherapeutic support during rehabilitation following the treatment of reproductive system MNs and to evaluate its effect on QoL indicators in women with neuropsychiatric disorders.Material and methods. The algorithm for the provision of comprehensive psychotherapeutic support included clinical interview, cognitive behavioral therapy, visualization, audio therapy, art therapy, group and individual psychotherapy, family psychotherapy, image therapy. …”
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