Network Pharmacology Approach to Unveiling the Mechanism of Wolfberry Mulberry Raspberry Decoction in the Treatment of Sepsis-Induced Myocardial Dysfunction by Zhang Q, Wen L, Li J, Liu P, Sun X, Liu Q, Chen X, Zhang Y

“…Qingqiong Zhang,1,* Lianbin Wen,1,* Junxian Li,2 Peng Liu,1 Xuechun Sun,1 Qingsong Liu,2,3 Xiaomei Chen,4 Yanfang Zhang5 1Department of Geriatric Cardiology, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, 610072, People’s Republic of China; 2Department of Traditional Chinese Medicine, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, 610072, People’s Republic of China; 3School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 4Department of Geriatrics, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 610075, People’s Republic of China; 5Department of Public Health Center, People’s Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, 750002, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yanfang Zhang, Department of Public Health Center, People’s Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, 750002, People’s Republic of China, Email zhangyanfang@nxrmyy.com Xiaomei Chen, Department of Geriatrics, Hospital of Chengdu University of Traditional Chinese Medicine, 39 Shi-Er-Qiao Road, Jinniu District, Chengdu, Sichuan, 610072, People’s Republic of China, Tel +86-18080407013, Email 3612556@qq.comObjective: To investigate the mechanisms by which the Wolfberry Mulberry Raspberry Decoction (WMRD) affects Sepsis-Induced Myocardial Dysfunction (SIMD) using network pharmacology and experimental validation.Methods: We explored the TCM Systems Pharmacology Database to gather biological data for WMRD compounds. …”
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Efficacy and Safety of Biologics Targeting Type 2 Inflammation in COPD: A Systematic Review and Network Meta-Analysis by Li S, Yi B, Wang H, Xu X, Yu L

“…Shujie Li,1,* Baiyi Yi,1,* Huan Wang,2 Xianghuai Xu,1 Li Yu1 1Department of Pulmonary and Critical Care Medicine, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, People’s Republic of China; 2Clinical Research Center, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xianghuai Xu, Department of Pulmonary and Critical Care Medicine, Tongji Hospital, School of Medicine, Tongji University, No. 389 Xincun Road, Shanghai, 200065, People’s Republic of China, Email 05849@tongji.edu.cn Li Yu, Department of Pulmonary and Critical Care Medicine, Tongji Hospital, School of Medicine, Tongji University, No. 389 Xincun Road, Shanghai, 200065, People’s Republic of China, Email 96778@tongji.edu.cnPurpose: This study aims to comparatively evaluate the efficacy and safety profiles of biologic agents targeting type 2 inflammation in COPD.Methods: As of September 1, 2024, we identified and screened eight clinical studies evaluating biologic agents targeting type 2 inflammation for COPD treatment from multiple databases. …”
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SIFusion: Lightweight infrared and visible image fusion based on semantic injection. by Song Qian, Liwei Yang, Yan Xue, Ping Li

“…Extensive experimental comparisons demonstrate that the proposed method performs excellently in terms of visual appeal and advanced semantics, providing satisfactory fusion results for subsequent high-level visual tasks even in challenging scenarios.…”
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Research hotspots and trends of sarcopenia in orthopaedic surgery: a bibliometric analysis from 2003 to 2023 by Ruijiang Li, Ruijiang Li, Yufeng Ge, Yufeng Ge, Yixiao Chen, Yixiao Chen, Gang Liu, Gang Liu, Feng Gao, Feng Gao, Chao Tu, Chao Tu, Ting Li, Ting Li, Ling Wang, Minghui Yang, Minghui Yang, Xinbao Wu, Xinbao Wu

“…PurposeThis study aimed to evaluate the current bibliometric characteristics, progress, and hotspots of cross-sectional research on orthopaedic surgery and sarcopenia over the past two decades.MethodsPublications related to sarcopenia and orthopaedic surgery, published between January 2003 and December 2023, were screened the Web of Science Core Collection. …”
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Traditional Chinese medicine diagnostic prediction model for holistic syndrome differentiation based on deep learning by Zhe Chen, Dong Zhang, Chunxiang Liu, Hui Wang, Xinyao Jin, Fengwen Yang, Junhua Zhang

“…Background: With the development of traditional Chinese medicine (TCM) syndrome knowledge accumulation and artificial intelligence (AI), this study proposes a holistic TCM syndrome differentiation model for the classification prediction of multiple TCM syndromes based on deep learning and accelerates the construction of modern foundational TCM equipment. Methods: We searched publicly available TCM guidelines and textbooks for expert knowledge and validated these sources using ten-fold cross-validation. …”
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Rapid Detection of Feline Calicivirus Using Lateral Flow Dipsticks Based on CRISPR/Cas13a System by Zichuang Zhang, Jing Li, Chengqi Zhang, Xue Bai, Tie Zhang

“…Eventually, the results indicated that the target gene could be effectively amplified by the Cas13a-RAA-LFD method, and the results could be visually observed by LFD. …”
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New Approach to Dominant and Prominent Color Extraction in Images with a Wide Range of Hues by Yurii Kynash, Mariia Semeniv

“…Traditional extraction methods often neglect visually salient colors that occupy small areas yet possess high aesthetic relevance. …”
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Scientific geovisualization of the dynamics of Sargassum dispersion and landfall in the Caribbean, based on satellite imagery and numerical forecasts. by Francisco Javier Osorno-Covarrubias, Jorge Prado Molina, Gabriela Gómez-Rodríguez, Uriel Mendoza, Stéphane Couturier

“…Further steps, beyond the scope of this study, would be required, including optimization of the remote sensing technique, improvement of the transport simulation methods, and an experimental framework for accuracy assessment. …”
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Phospholipid-Rich DC-Vesicles with Preserved Immune Fingerprints: A Stable and Scalable Platform for Precision Immunotherapy by Ramon Gutierrez-Sandoval, Francisco Gutierrez-Castro, Natalia Muñoz-Godoy, Ider Rivadeneira, Adolay Sobarzo, Luis Alarcón, Wilson Dorado, Andy Lagos, Diego Montenegro, Ignacio Muñoz, Rodrigo Aguilera, Jordan Iturra, Francisco Krakowiak, Cristián Peña-Vargas, Andres Toledo

“…No significant degradation was observed post-cryopreservation. Visualization through heatmaps, PCA, and volcano plots supported inter-condition consistency. …”
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Comprehensive evaluation and scenario simulation for determining the optimal conservation priority of ecological services in Danjiangkou Reservoir Area, China by Pengcheng Zhao, Lihui Wang, Yuhong Huang, Yifan Zhao, Qichi Yang, Jinliang Huang, Yun Du, Feng Ling

“…However, the utilization of a singular evaluation indicator and the employment of ambiguous methods for delineating conservation priorities have resulted in deviations in the decision-making processes. …”
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Hereditary Colorectal Cancer Syndromes: Small Bowel Cancer Risk and Endoscopic Surveillance Strategies by Edoardo Borsotti, Francesca Laura Nava, Felice Benedicenti, Laura Cini, Andrea Magarotto, Davide Ferrari, Paolo Cantù, Marco Vitellaro, Emanuele Rausa, Federica Cavalcoli

“…This review aims to evaluate and compare current endoscopic techniques for small bowel surveillance in these patients. <b>Methods:</b> A comprehensive review was conducted using peer-reviewed studies sourced from PubMed. …”
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Quantitative analysis of three-dimensional choroidal changes in coronary artery disease patients with swept-source optical coherence tomography angiography by Zhaoxia Zheng, Jing Liu, Jiayi Sun, Yue Zhang, Xiaoya Gu, Shuang Song, Xiaobing Yu

“…Purpose: To quantitatively analyze three-dimensional (3D) choroidal changes in coronary artery disease (CAD) patients with swept-source optical coherence tomography angiography (SS-OCTA) based on a scan area of 12×12mm. Methods: 236 CAD patients and 78 controls were included after coronary angiography (CAG) evaluation in this prospective cross-sectional study. …”
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Pre-treatment peripheral blood TCR repertoire as a predictor of response in patients with NSCLC treated with immunochemotherapy by Yong Yang, Hui-yu Jiang, Yuan Li, Fang Wu, Zhao-yang Chen, Guo-ping Zheng, Wen-Zhong Su, Hai-long Wang, Min Pang

“…Therefore, further investigation and validation of the TCR repertoire as a potential biomarker for predicting the benefit of immune checkpoint inhibitor therapy are needed. Methods Blood samples were collected from patients with advanced NSCLC before initiating anti-programmed cell death 1 (anti-PD-1) antibody treatment in combination with chemotherapy. …”
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Comparative study of robotic-assisted vs. laparoscopic surgery for colorectal cancer: a single-center experience by Wenpeng Wang, Jia Liu, Jiefu Wang, Li Li, Dalu Kong, Junfeng Wang

“…This study aimed to compare clinical and surgical outcomes between RACS and LCS for CRC patients.MethodsWe included 225 patients from Tianjin Medical University Cancer Institute &amp; Hospital (TJMUCH) between January 2021 and June 2024, divided into RACS (n=82) and LCS (n=143) groups. …”
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Tourniquet Use During Anterior Cruciate Ligament Reconstruction Is Associated With Postoperative Quadriceps Atrophy and Pain but No Negative Effects in the Long Term: A Systematic... by Caleb V. Hayes, B.S., Saad M. Ibrahim, B.S., Anna E. Crawford, B.S., James R. Jones, M.D., Mathew D. Hargreaves, B.S., Clay A. Rahaman, B.A., Eugene W. Brabston, M.D., Thomas B. Evely, M.D., Aaron J. Casp, M.D., Kevin E. Wilk, D.P.T., Amit M. Momaya, M.D.

“…Outcomes evaluated included intraoperative visualization, pain, quadricep strength thigh or calf girth, blood loss, and operative time. …”
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Air pollution and prostate cancer: Unraveling the connection through network toxicology and machine learning by Yuqi Li, Tao Zhou, Zhiyu Liu, Xinyao Zhu, Qilong Wu, Chunyang Meng, Qingfu Deng

“…This study aims to explore the potential association between air pollutants and prostate cancer (PCa) and to identify key genes that may play a critical bridging role in this process. Methods: This study utilized multiple online databases to obtain relevant target genes associated with air pollutants and PCa. …”
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Automated non-laying hen identification via deep learning: A phenotypic characteristics attribution analysis framework by Wenxiang Qin, Xiao Yang, Liyang Yu, Yujia Chen, Junjie Wang, Yan Zhou, Weichao Zheng

“…The current identification of non-laying hens in commercial layer operations relies predominantly on manual empirical methods involving visual inspection and physical touch. …”
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A bibliometric analysis of research trends in mesenchymal stem cell therapy for neonatal bronchopulmonary dysplasia: 2004–2024 by Lu Bai, Yue Xin

“…Despite the growing body of preclinical evidence, visualization of publication patterns reveals significant gaps between laboratory findings and clinical applications, with only 8.2% of publications reporting clinical outcomes. …”
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Burn inhalation injury and intubation with dexamethasone-eluting endotracheal tubes modulate local microbiome and alter airway inflammation by Gabriela Gonzales, Ronit Malka, Rena Bizios, Gregory R. Dion, Teja Guda, Teja Guda

“…A secondary aim is to assess the impact of localized dexamethasone delivery via a drug-eluting ETT to reduce laryngeal scarring.MethodsInhalation injury was developed in swine by administering heated air (150°C–160°C) under endoscopic visualization. …”
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Tips and Tricks in the Laparoscopic Treatment of Type I Duodenal Atresia: Description of a Technique by Salvatore Fabio Chiarenza, Maria Luisa Conighi, Valeria Bucci, Cosimo Bleve

“…Intraduodenal Indocyanine Green (ICG) visualization (under near-infrared light) was used in the last two cases. …”
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