Association of Estimated Glucose Disposal Rate With Risk of Abdominal Aortic Aneurysm: Evidence From a Large-Scale Prospective Cohort Study of the UK Biobank by Yuanwei Chen, Ting Zhou, Songyuan Luo, Jizhong Wang, Fan Yang, Yingqing Feng, Lixin Fang, Jianfang Luo

“…Kaplan–Meier curves were generated to visualize cumulative AAA incidence across eGDR quartiles, whereas restricted cubic splines (RCSs) were applied to characterize the exposure–response relationship. …”
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Effect of Traditional Chinese Medicine nursing on functional rehabilitation and postoperative complications in patients undergoing percutaneous transforaminal endoscopic surgery fo... by XU Li (徐丽)

“…The Oswestry Disability Index (ODI), Visual Anlogue Scale (VAS) and Japanese Orthopaedic Association scores (JOA) were used to evaluate the postoperative function recovery. …”
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ML Auditing and Reproducibility: Applying a Core Criteria Catalog to an Early Sepsis Onset Detection System by Markus Schwarz, Ludwig Christian Hinske, Ulrich Mansmann, Fady Albashiti

“…In this paper, we apply our catalog to an early sepsis onset detection system use case. Methods: The assessment of the ML algorithm behind the sepsis prediction system takes place in a kind of external audit. …”
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The influence of the interfacing angle between the pedicle screw and support rods on the clinical outcomes after posterior lumbar-sacral topping-off surgery: A retrospective clinic... by Mingzheng Zhao, Honghao Yang, Shixuan Guo, Fengqi Cheng, Yaoshen Zhang, Yong Hai, Yuzeng Liu

“…Methods This study is a monocentric retrospective observational study that included patients diagnosed with lumbosacral degenerative disease and underwent topping-off surgery. …”
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Treatment of Patients With Vertical Maxillary Excess: Orthognathic Surgery vs Strategic Implant® (Clinical Cases Report) by A. Ihde, A. Chakranarayan, O. Sipic, P. Soni, S. Ihde, Y. Vares

“…The evaluation criteria taken into account were visual results of treatment of vertical maxillary excess and mandibular deficiency, tooth and gum show at rest and smile, time spent on rehabilitation of the treated patients, total chair time, duration of pain etc. …”
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Comparative analgesic efficacy of ultrasound-guided nerve blocks induced by three anesthetics with different duration of action in the treatment of resistant neuropathic pain in th... by Jovanikić Olivera, Anđelić Gordana, Lepić Milan, Mirković Dušica, Jovanović Bojan, Dragović Tamara, Pavličević Goran, Lepić Toplica

“…The nerve blocks were administered on a daily basis until the relief of pain (visual analogue scale – VAS < 30), and after that, two additional nerve blocks were given. …”
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Research Progress in Urban Pollinator-Friendly Landscape Construction by Guiying LI, Hanwen XIAO, Runan TIAN

“…In order to make full use of the protective effect of urban green spaces on pollinator communities, while improving the benefits of urban ecosystems, it is very significant to clarify a systematic approach for the construction of pollinator-friendly landscapes and to point out the future development direction of the field of pollinator-friendly landscapes in Chinese cities.MethodsThis research is based on VOS viewer software to visualize and analyze the effective literature in the field of pollinator-friendly landscapes filtered from Web of Science core database, Google Scholar and X-MOL academic platform. …”
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H2FPEF and HFA‐PEFF scores for heart failure risk stratification in hypertrophic cardiomyopathy patients by Yi‐Peng Gao, Hong‐Yun Liu, Xiao‐Jun Bi, Jie Sun, Ying Zhu, Wei Zhou, Ya‐Ting Fan, Xue‐Qing Cheng, Pei‐Na Huang, Ya‐Ni Liu, You‐Bin Deng

“…This study aimed to explore the value of the H2FPEF and HFA‐PEFF scores for HF risk stratification in patients with hypertrophic cardiomyopathy (HCM). Methods and results In this cohort study, 1068 HCM patients were included. …”
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Antimicrobial efficacy of methylene blue-functionalized graphene oxide-mediated photodynamic therapy against Enterococcus faecalis in root canal disinfection by Rizwan Jouhar, FCPS, Mohamad Syahrizal Halim, M.Rest.Dent, Sayed A. Quadri, MD, Muhammad Adeel Ahmed, PhD, Faheem Shah, PhD

“…Six experimental groups with equal numbers of samples (n = 15) were treated with 5 % NaOCl (groups 1 and 2), MB-based PDT (groups 3 and 4), or MB/rGO-based PDT (groups 5 and 6). …”
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Delivery of miR-26a-5p by Subcutaneous Adipose Tissue-Derived Extracellular Vesicles Alleviates Acute Lung Injury in Mice Through CHUK/NF-&amp;kappa;B Pathway by Xie Y, Ran L, Yue C, Wang C, Chen F, Su Y, Qin Y, Zhang Q, Liu J, Du N, Zhang L, Jiang Y, Liu G

“…This study aimed to elucidate the immunomodulatory roles and underlying mechanisms of adipose tissue-derived EVs in the pathogenesis of ARDS.Methods: Subcutaneous adipose tissue extracellular vesicles (SAT-EVs) were collected from the mice via ultracentrifugation. …”
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Genetic Variants of UGP2 and FBP2 in the Glycolysis Pathway Independently Predict Survival of Patients with HBV-Related Hepatocellular Carcinoma by Gong R, Qiu M, Liu Y, Cao J, Zhou Z, Lin Q, Jiang Y, Liang X, Wei Y, Wen Q, Chen P, Wei X, Wei J, Zhan S, Zhang R, Ye D, Yu H

“…However, the effect of genetic variants in glycolysis pathway genes in survival of patients with hepatitis B virus-related hepatocellular carcinoma (HBV-HCC) remains unclear.Methods: We employed multivariable Cox proportional hazards regression analyses to estimate associations between genetic variants in 240 glycolysis pathway genes and overall survival (OS) of 866 patients with HBV-HCC, and we also used false positive report probability for multiple testing corrections.Results: We found that UGP2 rs4293553 G allele was significantly associated with a better OS of HBV-HCC patients [hazards ratio (HR) = 0.73, 95% confidence interval (CI) = 0.62– 0.86, P &lt; 0.001], and that FBP2 rs635087 G allele was significantly associated with a worse OS in these patients (HR = 1.38, 95% CI = 1.18– 1.61, P &lt; 0.001). …”
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IL-17A as a Key Mediator of Pulmonary-Intestinal Immune Interactions in a Mouse Model of Asthma and Colitis by Wu C, Hu X, Mo Z, Meng Y, Du Y, Duan Y, Zeng Z, Shan J, Li J, Zhang N, Ma Y, Wang H, Liu C, Zhang G, Foster PS, Xu H, Li F, Yang M

“…While IL-17A has been implicated in both asthma and colitis independently, its role in coordinating systemic immune responses across tissue compartments is not well defined.Methods: In this study, we developed a combined house dust mite-induced asthma model and dextran sulfate sodium-induced colitis model to investigate the role of IL-17A in driving inflammation in both the lungs and the intestines.Results: Our findings demonstrate that IL-17A neutralization markedly reduced airway and intestinal inflammation, attenuated mucus hypersecretion, downregulated pro-inflammatory cytokine expression, and alleviated colitis severity. …”
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Radiation-Based Multi-Modal Therapy Combining with Immunotherapy to Develop a Vaccine-Like Effective Treatment for Triple-Negative Breast Cancer by Dai M, Tian Z, Xu F, Yao B, Liang H, Li D, Wang J, Rong J, Liu T, Tang H, Lu H, Zhang W

“…Current treatments like chemotherapy and immunotherapy face challenges due to chemotherapy side effects, limited immunotherapy applicability, and TNBC&amp;rsquo;s immunosuppressive microenvironment.Purpose: To achieve a more effective treatment for TNBC, a novel therapeutic strategy has been developed, which uses X-ray excited photodynamic therapy (X-PDT) to activate the tumor immune microenvironment following with the immunotherapy of Anti-CTLA4.Methods: Base on the 4T1 tumor mouse model, this study initially investigated the regulatory effects of X-PDT on the tumor immune microenvironment. …”
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Sodium-glucose co-transporter-2 inhibitors in patients with chronic kidney disease with or without type 2 diabetes: systematic review and meta-analysis by Gordon Guyatt, Arnav Agarwal, Thomas Agoritsas, Haoming Tian, Sheyu Li, Chang Xu, Ping Fu, Qingyang Shi, Xiaoxi Zeng, Per Olav Vandvik, Xinyu Zou, Yunhe Mao, Qinbo Yang, Xianghang Luo, Belen Ponte

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HMGB1 Inhibition Alleviates Chronic Nonbacterial Prostatitis by Suppressing M1 Polarization of Macrophages by Zhou J, Ding L, Chen J, Chen C, Jiang P, Mei Z, Jiang Q, Hua X

“…This study aimed to investigate HMGB1’s potential contributions to the pathogenesis of CP/CPPS, offering new perspectives for innovative treatments.Materials and Methods: We have successfully extracted prostate antigens from Sprague–Dawley rat prostate tissue and established an experimental autoimmune prostatitis (EAP) mouse model in non-obese diabetic (NOD) mice. …”
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Identification of Single-Nucleotide Polymorphisms in B3GAT2, CPQ, and HPSE Genes in the Liver Tissue of Arian Broilers with Ascites using RNA-seq Data by Somayeh Hassnvand, Ayoub Farhadi, Elham Yonesi, Ghodrat Rahimimianji, Karim Hasan Pur

“…The present study aimed to identify single-nucleotide polymorphisms (SNPs) in CPQ, B3AGT2, and HPSE genes in the liver tissue of Arain broiler chickens with ascites syndrome using RNA-seq data. Methods: This research was conducted in two phases, including the first phase (ascites induction) and the second phase (normal rearing conditions). …”
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Alcohol intake and pancreatic cancer risk: An analysis from 30 prospective studies across Asia, Australia, Europe, and North America. by Sabine Naudin, Molin Wang, Niki Dimou, Elmira Ebrahimi, Jeanine Genkinger, Hans-Olov Adami, Demetrius Albanes, Ana Babic, Matt Barnett, David Bogumil, Hui Cai, Chu Chen, A Heather Eliassen, Jo L Freudenheim, Gretchen Gierach, Edward L Giovannucci, Marc J Gunter, Niclas Håkansson, Mayo Hirabayashi, Tao Hou, Brian Z Huang, Wen-Yi Huang, Harindra Jayasekara, Michael E Jones, Verena A Katzke, Woon-Puay Koh, James V Lacey, Ylva Trolle Lagerros, Susanna C Larsson, Linda M Liao, Kenneth Lo, Erikka Loftfield, Robert J MacInnis, Satu Männistö, Marjorie L McCullough, Anthony Miller, Roger L Milne, Steven C Moore, Lorelei A Mucci, Marian L Neuhouser, Alpa V Patel, Elizabeth A Platz, Anna Prizment, Kim Robien, Thomas E Rohan, Carlotta Sacerdote, Sven Sandin, Norie Sawada, Minouk Schoemaker, Xiao-Ou Shu, Rashmi Sinha, Linda Snetselaar, Meir J Stampfer, Rachael Stolzenberg-Solomon, Cynthia A Thomson, Anne Tjønneland, Caroline Y Um, Piet A van den Brandt, Kala Visvanathan, Sophia S Wang, Renwei Wang, Elisabete Weiderpass, Stephanie J Weinstein, Emily White, Walter Willett, Alicja Woslk, Brian M Wolpin, Shiaw-Shyuan S Yaun, Chen Yuan, Jian-Min Yuan, Wei Zheng, Paul Brennan, Stephanie A Smith-Warner, Pietro Ferrari

“…We examined the association between alcohol intake and pancreatic cancer risk in a large consortium of prospective studies.<h4>Methods and findings</h4>Population-based individual-level data was pooled from 30 cohorts across four continents, including Asia, Australia, Europe, and North America. …”
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Unveiling the antiurolithiatic potentiality of two benzene sulfonamide derivatives against ethylene glycol-induced renal calculi by Ahmed M. Elgendy, Mohamed S. Nafie, Zohour I. Nabil, Nahla S. El-Shenawy, Heba N. Gad El-Hak

“…Conclusion: Both compounds were found to possess equal effectiveness in inhibiting the complications of stone formation. …”
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Characterizing ECOPD Phenotypes: Associations with In-Hospital Outcomes and Immunoinflammatory Mechanisms by Wang Q, Wang L, Zhang L, Zhao C, Liu Y, Liu L, Yuan L, Feng M, Wang G, Li L, Zhang S, Yuan Y, Kang D, Zhang X

“…We sought to explore the underlying mechanisms that contribute to the relationship between ECOPD phenotypes and these outcomes.Methods: A k-means cluster analysis was conducted on 20,890 recruited patients hospitalized for ECOPD. …”
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The Hydrocephalus Association Patient-Powered Interactive Engagement Registry (HAPPIER): Design and Initial Baseline Report by Jakopin NE, Lanjewar SN, Garzon A, Gross P, Holubkov R, Moghekar A, Preston J, Romanoski M, Shannon CN, Tamber MS, Van der Willigen T, Sloan M, Chau MJ, Koschnitzky JE

“…This publication introduces the registry by highlighting the demographics, etiology, treatments, symptom profiles, and diagnosed comorbidities of the participants.Methods: The Hydrocephalus Association and a 10-member steering committee developed HAPPIER. …”
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