Survival Prediction of Esophageal Cancer Using 3D CT Imaging: A Context-Aware Approach With Non-Local Feature Aggregation and Graph-Based Spatial Interaction by Fuce Guo, Chen Huang, Shengmei Lin, Yongmei Dai, Qianshun Chen, Shu Zhang, Xunyu XU

“…In the current study, we aimed to develop an effective EC survival risk prediction using only 3D computed tomography (CT) images.The proposed model consists of two essential components: 1) non-local feature aggregation module(NFAM) that integrates visual features from tumor and lymph nodes at both local and global scales, 2) graph-based spatial interaction module(GSIM) that explores the latent contextual interactions between tumors and lymph nodes.The experimental results demonstrate that our model achieves superior performance compared to state-of-the-art survival prediction methods, emphasizing its robust predictive capability. …”
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Vertebral Column Decancellation for Correcting Cervicothoracic Kyphotic Deformity in Patients With Ankylosing Spondylitis by Han Yu, Qi Wang, Yiming Fan, Dengbin Qi, Tianhao Wang, Bing Li, Yi Huang, Ze Wang, Chao Xue, Guoquan Zheng

“…The purpose of the present study was to retrospectively analyze and evaluate the effect of VCD on cervicothoracic kyphotic deformity in patients with AS. Methods Records of eight patients with cervicothoracic kyphotic deformity who underwent VCD at C7 in our institution were retrospectively reviewed. …”
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The clinical efficacy of auricular acupuncture in the treatment of frequent episodic tension-type headache: a single-blind randomized controlled trial by Xiaxia Jin, Ziwen Xu, Tao Gao, Gaofeng Wang, Wendi Dong, Junyi Jin, Yongmei Yan

“…Purpose This study aimed to compare the efficacy and safety of auricular acupuncture and sham acupuncture in treating FETTH. Methods This was a randomized controlled trial. Participants with FETTH were randomly assigned in a 1:1 ratio to receive auricular acupuncture or sham acupuncture for 4 weeks, with follow-up lasting for up to 24 weeks. …”
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Clinical and biochemical characteristics of patients with acromegaly and normal or increased prolactin levels by Yuliya A. Kukushkina, Irena A. Ilovayskaya

“…Aim: To identify hallmarks of clinical and biochemical parameters in patients with acromegaly and normal or increased prolactin level. Methods: We performed a single center, single sample retrospective, observational cohort uncontrolled non-interventional study in 306 patients (70 men and 236 women) with acromegaly examined from July 2021 to June 2024, 50 of them with a pituitary microadenomas and 256 with macroadenomas. …”
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Influence of Irrigant Activation Techniques on External Root Temperature Rise and Irrigation Penetration Depth in 3D-Printed Tooth Model: An In Vitro Study by Ali Addokhi, Ahmed Rahoma, Neveen M. A. Hanna, Faisal Alonaizan, Faraz Farooqi, Shimaa Rifaat

“…Irrigant penetration, with and without BMH, was assessed in 3D-printed premolars using a 2.5% sodium hypochlorite-contrast medium mixture, visualized with a CMOS radiographic sensor. Penetration was scored (main canal: 3 points; lateral canals: 0–2 points) and analyzed with non-parametric tests. …”
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Induction heating combined with antibiotics or SAAP-148 effectively reduces biofilm-embedded Staphylococcus aureus on a fracture-related implant mimic by Marielle Verheul, Anne A. Wagenmakers, Rob G. H. H. Nelissen, Peter H. Nibbering, Bart G. Pijls

“…Biofilm-embedded bacteria were harvested by sonication to determine the bacterial load and visualized by confocal microscopy (LIVE/DEAD). Results: NCIH to 60°C, 70°C, and 80°C reduced biofilm-embedded MRSA and MSSA by 2.3-log, 4.9-log, 5.5-log, and 1.1-log, 3.4-log, and 6.6-log CFU/ml, respectively. …”
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Evaluating the MPM III and SAPS III prognostic models in a war-affected, resource-limited setting: a prospective study from the Gaza Strip by Belal Aldabbour, Ahmed J. H. Elhissi, Hamza Abudaqqa, Jaser Alqrinawi, Mohammed Badran, Mohammed Sulaiman, Yousef Alsoos, Yousef Altartour, Mohammed Abulebda, Mohammed Muhaisen, Omar Alsafadi, Zuhair Assaf

“…Furthermore, the difference between the predicted and actual mortality rates was visualized, and standardized mortality rates (SMR) were calculated. …”
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Oral health status, oral hygiene behaviors, and caries risk assessment of individuals with special needs: a comparative study of Pakistan and Saudi Arabia by Osama Khattak, Farooq Ahmad Chaudhary, Shahzad Ahmad, Muhammad Amber Fareed, Shazia Iqbal, Asma Shakoor, Mohammed Nadeem Baig, Haifa Ali Almutairi, Rakhi Issrani, Azhar Iqbal

“…This study aims to: (1) assess the oral health status of disabled individuals in Pakistan and Saudi Arabia, (2) evaluate their oral hygiene knowledge and behaviors, and (3) determine their caries risk using the Caries Management by Risk Assessment (CAMBRA) protocol. Methods A cross-sectional study was conducted on 189 participants aged 13 years and older, including both young people and adults with hearing, visual, or intellectual disabilities from Pakistan and Saudi Arabia between September 2023 and April 2024. …”
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Prognostic analysis of sepsis-induced myocardial injury patients using propensity score matching and doubly robust analysis with machine learning-based risk prediction model develo... by Pan Guo, Pan Guo, Li Xue, Fang Tao, Kuan Yang, YuXia Gao, Chongzhe Pei

“…This study aimed to evaluate the prognostic impact of SIMI and develop validated predictive models using advanced machine learning (ML) algorithms for identifying SIMI in critically ill sepsis patients.MethodsData were sourced from the Medical Information Mart for Intensive Care IV (MIMIC-IV, v3.0) database. …”
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Susceptibility-weighted MR imaging (SWI) of basal ganglia iron deposition in the early and advanced stages of Parkinson's disease by A. G. Trufanov, A. A. Yurin, A. B. Buriak, S. A. Sandalov, M. M. Odinak, I. V. Litvinenko

“…The accumulation of iron is visualized as an area of reduced signal intensity on SWI, and its estimation in accordance with the SPIN program has accordingly a smaller value. …”
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Effectiveness of AI-Driven Conversational Agents in Improving Mental Health Among Young People: Systematic Review and Meta-Analysis by Yi Feng, Yaming Hang, Wenzhi Wu, Xiaohang Song, Xiyao Xiao, Fangbai Dong, Zhihong Qiao

“…Pooled effect sizes (Hedges g) were calculated using random effect models and visually presented in forest plots. ResultsA total of 14 articles (including 15 trials) were included, involving 1974 participants. …”
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Development of a Serious Game to Simulate Neonatal Intensive Care Unit Experiences: Collaborative Quasi-Experimental Study by Yukihide Miyosawa, Koichi Hirabayashi, Kodai Yamada, Fumiya Kobayashi, Nanami Ogihara, Noa Takeda, Eri Okamura, Shogo Matsumura

“…Structured as a 6-chapter visual novel, the game follows a high school student observing the NICU during a hospital internship. …”
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Enhanced Teleoperation of Robotic Arms Through Master-Slave Configuration With Multithreading by Ahmad Faiz Fawzan Ahmad Zainudin, Mohd Hairi Mohd Zaman, Mohd Faisal Ibrahim, Mohd Asyraf Zulkifley, M. Marzuki Mustafa

“…Low-pass filtering techniques were applied to suppress signal noise and improve trajectory smoothness, while multithreading methods were used to separate sensor polling and data transmission processes. …”
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Reliability and Validity Study of the <italic>International Classification of Functioning</italic>，<italic>Disability and Health Rehabilitation Set</italic> in Rehabilitation of Kn... by LEI Lei, PENG Zhizhou, GAO Mingyue, LI Fei, MAO Ningning, WU Xi, XIAO Chengcheng, XUN Yajing, ZHAO Suchen, FAN Xiaojun

“…ObjectiveTo explore the reliability and validity of the <italic>International Classification of Functioning, Disability and Health Rehabilitation Set</italic> (ICF-RS) in assessing the body function, activities and social participation of patients with knee osteoarthritis (KOA).MethodsA total of 60 KOA patients in the Outpatient Department of Orthopedic Rehabilitation in the Fifth Hospital of Xiamen and the Xiangyang Central Hospital from October to December 2022 were recruited. …”
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A 360° Approach to Personalize Lifestyle Treatment in Primary Care for People With Type 2 Diabetes: Feasibility Study by Zeena Harakeh, Iris de Hoogh, Anne-Margreeth Krijger-Dijkema, Susanne Berbée, Gino Kalkman, Pepijn van Empelen, Wilma Otten

“…ObjectiveThis work examines the acceptability, implementation, and potential effects of the 360° diagnostic tool and subsequent tailored treatment (360° approach) in a 6-month intervention and feasibility study conducted in standard primary health care settings in the Netherlands. MethodsA single-group design with baseline, 3-month, and 6-month follow-ups was used. …”
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The clinical efficacy of hybrid surgery based on the Waveflex semi-rigid dynamic internal fixation system for the treatment of lumbar degenerative diseases: over three-year follow-... by Zhiwu Zhang, Jiashen Shao, Nan Su, Xiang Li, Qi Fei, Yong Yang, Hai Meng

“…Abstract Objective To investigate the efficacy and safety of hybrid surgery based on the Waveflex internal fixation system for the treatment of lumbar degenerative disease. Methods A retrospective analysis was conducted on 31 consecutive patients who underwent hybrid surgery (fusion combined with non-fusion surgery) using the Waveflex internal fixation system for lumbar degenerative diseases between December 2019 and May 2021. …”
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Defining the relationship between clinician-rated ECOG performance status and patient-reported health-related quality of life scores in men with metastatic hormone-naïve prostate c... by Ikenna I. Nnabugwu, Eric N. Obikeze, Chinwe A. Nnabugwu, Solomon K. Anyimba, Okwudili C. Amu, Okezie M. Mbadiwe, Kevin S. N. Echetabu, Ijeoma L. Okoronkwo

“…The mean FACT-P score, health utility index (HUI) and visual analogue scale (VAS) scores were 80.18 ± 17.56, 0.524 ± 0.324 and 60.43 ± 9.91% respectively. …”
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Development of Rifampicin Eye Drops for the Treatment of Exudative Age-Related Macular Degeneration by Valory Anne S. Vailoces, Andrew J. Tolentino, Jose Fernando Arevalo, Ron A. Adelman, Robert Bhisitkul, Diana V. Do, Quan Dong Nguyen, Michael J. Tolentino, Masaki Tanito, Hiroaki Serizawa

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Early peripapillary neurovascular injury and its relevant systemic factors in type 2 diabetic patients without retinopathy: An OCTA based study by Haochen Jin, Kaiyue Wang, Changhong Ren, Shan He, Yuan Gao, Xiaofang Liang, Xuxiang Zhang

“…Retinal microvascular and microstructural networks were visualized using spectral domain optical coherence tomography angiography. …”
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CYFIP2: potential pancreatic cancer biomarker and immunotherapeutic target by Cong Xiao, Xiaojuan Zhang, Bobo Hou, Ping Wan, Zhenjun Cao, Xuefeng Rao

“…In this work, we first explain the great potential of CYFIP2 malignant progression from a broader perspective (pan-cancer) and confirm its oncogenic value in pancreatic cancer. Methods The Cancer Genome Atlas (TCGA), Genotype-Tissue Expression (GTEx) database, CELL and GEO databases were utilized to explore the distribution of the CYFIP2 gene in human cancers. …”
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