Effects of single subanesthetic dose of oxycodone on pain and Th1/Th2 balance in patients after radical mastectomy by QU Na，ZHAO Xiaohong，NI Qiang

“…Objective To compare the effects of oxycodone and fentanyl on postoperative pain relief，immune balance of T-helper cells（Th），and adverse reactions in radical mastectomy. Methods A total of 120 female patients whounderwent elective radical mastectomy at Shanghai Public Health Clinical Center between December 2021 and January2024 were selected for this study. …”
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Effects of PRP injection combined with intersecting femoral head decompression versus combined with multiple core decompression in the treatment of avascular necrosis of femoral he... by Lei Sun, Ziyao Xu, Zhongyuan Zhang, Jinwei Zhao, Mengshuai Sun, Guangling Gao, Fang Gao, Hongjiang Jiang, Changjun Ju

“…The objective of this study is to evaluate the effect of PRP injection combined with intersecting femoral head decompression versus combined with multiple core decompression (MCD) in the treatment of ANFH. Methods A retrospective cohort analysis comparing two surgical interventions was conducted between January 2020 and December 2020. …”
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Qualitative and quantitative ultrasound parameters of carotid atherosclerotic plaques in patients with moderate cardiovascular risk according to the SCORE scale: 7-year prospective... by O. A. Pogorelova, M. I. Tripoten, I. S. Melnikov, L. Sh. Khamchieva, B. M. Tamaeva, S. G. Kozlov, T. V. Balakhonova

“…Plaque number, maximum plaque height, total plaque height, total CA stenosis, visual plaque morphology, gray-scale median (GSM), and intima- media thickness of the right and left common CAs were assessed. …”
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Comparison of Milligan-Morgan Haemorrhoidectomy versus Laser Haemorrhoidoplasty in Patients with Grade II and III Haemorrhoids: A Prospective Observational Study by Asfar Ahamed Nawabjan, Sathish Rajkumar, Chudar Arumugam, Mohamed Marzook, Jasmine Sharmila, Lalith Kumar

“…The laser group had significantly lower postoperative pain {Visual Analogue Scale (VAS) 4.60±1.14 vs. 9.15±0.67 on Day 1, p<0.001}, shorter operative time (19.85 min vs. 54.75 min), reduced intraoperative blood loss (7±2.51 mL vs. 23±5.23 mL, p<0.001), and shorter hospital stay (1.1 vs. 1.85 days, p<0.001). …”
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Anatomical hemorrhoidectomy and semi-shutting suture combined with mucosal ligation for mixed hemorrhoids by Yuan Ke, Lei Yinfu, Chen Lina, Yu Lelai, Liu Huan, Shen Qingbo, Huang Qi, Pei Xi

“…[Objectives] To investigate the effect of anatomical hemorrhoidectomy and semi-shutting suture combined with mucosal ligation for mixed hemorrhoids. [Methods] Eighty patients with mixed hemorrhoids treated at our hospital between May 2019 and May 2020 were recruited and randomly assigned to the treatment and control group using the random number table. …”
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Safety and efficacy of robot-assisted percutaneous kyphoplasty under local anesthesia in a day-surgery setting for osteoporotic vertebral compression fractures by Yaming Wu, Yang Yuan, Yi Yin, Yaqin Gong, Yaowei Ye, Li Wu, Lizhen Qian

“…This retrospective study evaluates the safety and efficacy of robot-assisted percutaneous kyphoplasty (PKP) performed under local anesthesia within a day-surgery framework.MethodsClinical data from 127 patients with OVCFs who underwent robot-assisted PKP under local anesthesia in a day-surgery setting at the First People's Hospital of Kunshan between May 2022 and April 2024 were retrospectively analyzed. …”
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Knowledge of telemedicine and its associated factors among health professional in Ethiopia: A systematic review and meta-analysis. by Adamu Ambachew Shibabaw, Alex Ayenew Chereka, Agmasie Damtew Walle, Addisalem Workie Demsash, Geleta Nenko Dube, Abiy Tasew Dubale, Sisay Yitayh Kassie, Gemeda Wakgari Kitil, Mesafint Zewold Jember, Chernet Desalegn Gebeyehu, Aster Temesgen Ariger, Eshetie Andargie Dires

“…The funnel plot was visually inspected, and Egger's regression test was run to check for publication bias. …”
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Noninferiority of 0.25% versus 0.375% Ropivacaine in Popliteal Sciatic and Saphenous Nerve Blocks for Analgesia After Foot and Ankle Surgery: A Randomized Self-Paired Noninferiorit... by Wu L, Xi C, Lei G, Li H, Yin Y, Wan M, Wu H, Wang Y, Hu C, Wang G

“…Hence, we hypothesized that the analgesic effect of 0.25% ropivacaine would be noninferior to that of 0.375% ropivacaine at the same volume and would reduce the degree of weakness.Patients and Methods: In this randomized, double-blind, self-paired, noninferiority trial, 31 patients who were scheduled for similar, elective, bilateral foot and ankle surgeries under general anesthesia combined with popliteal sciatic and saphenous nerve blocks were enrolled. …”
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Cognitive Disorders In Acquired Sensorineural Hearing Loss, At The Ent Department Of The &ldquo;Village Bondeko&rdquo; Center, In Kinshasa by Masamba GR, Sokolo Gedikondele J, Longo-Mbenza B, Nganga Nkanga MS, Matanda Nzanza R, Matonda-ma-Nzuzi T, Ikanga J, Nge Okwe A, Lema Mabwaka G, Mawalala Malengele H, Nangi Mampuya C, Lumbu Malundama D

“…Thus, the objective of the present study was to investigate the relationship between sensorineural hearing loss and cognitive disorders in a correlational approach.Methods: This is a cross-sectional and analytical study conducted in the ENT department of the Center for the Disabled (visual, auditory, and mental) “Village Bondeko”, from June to September 2023, involving 150 adults (≥ 20 years) with acquired sensorineural hearing loss; without a history of neuropsychic disorders. …”
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Assessment of publication time in Campbell Systematic Reviews: A cross‐sectional survey by Bei Pan, Long Ge, Xiaoman Wang, Ning Ma, Zhipeng Wei, Lai Honghao, Liangying Hou, Kehu Yang

“…There was no significant difference between Campbell coordinating groups' median publication times and time gap from searches of databases to full review publication existed. However, the methods group only published one full review with almost a 3‐year time gap from searches of databases to review publication. …”
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Analysis of clinical knowledge, absenteeism and availability of resources for maternal and child health: a cross-sectional quality of care study in 10 African countries by Laura Di Giorgio, David K Evans, Magnus Lindelow, Son Nam Nguyen, Jakob Svensson, Waly Wane, Anna Welander Tärneberg

“…Objective Assess the quality of healthcare across African countries based on health providers’ clinical knowledge, their clinic attendance and drug availability, with a focus on seven conditions accounting for a large share of child and maternal mortality in sub-Saharan Africa: malaria, tuberculosis, diarrhoea, pneumonia, diabetes, neonatal asphyxia and postpartum haemorrhage.Methods With nationally representative, cross-sectional data from ten countries in sub-Saharan Africa, collected using clinical vignettes (to assess provider knowledge), unannounced visits (to assess provider absenteeism) and visual inspections of facilities (to assess availability of drugs and equipment), we assess whether health providers are available and have sufficient knowledge and means to diagnose and treat patients suffering from common conditions amenable to primary healthcare. …”
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Effectiveness of telerehabilitation in non-operatively managed shoulder conditions: a systematic review and meta-analysis by Ting-wan Lin, Yang Yang, Hai-yan Hong, Xiao-bo Zhou, Tao-Hsin Tung, Bin-bin Zheng, Jian-min Zhang

“…However, its overall efficacy remains uncertain due to inconsistent findings in prior studies. Methods This systematic review and meta-analysis assessed the effectiveness of telerehabilitation for non-operatively managed shoulder conditions, concentrating on randomized controlled trials (RCTs). …”
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Resting-state functional magnetic resonance imaging findings in patients with acoustic neuroma and tinnitus by ZHAN Xiaolin, REN Yi, LI Yongpeng, HUANG Qiao, YIN Shihua

“…Conclusion This study reveals the changes in the brain regions associated with tinnitus in acoustic neuroma involving multiple networks of the central nervous system, including the auditory network, visual network, default mode network and dorsal attention network. …”
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U-shaped association between serum chloride and hypertension risk with nadir around 103 mmol/L: insights from regression and interpretable machine learning (XGBoost/SHAP) using NHA... by Shancheng He, Xuemei Zhong, Guangming Chen, Long Li

“…This research attempted to explicate the link between serum levels of chloride and the risk of hypertension occurrence, as well as to identify the threshold level at which the risk undergoes changes across the general population and various demographic segments.MethodsEmploying materials from the to 2017–2018 National Health and Nutrition Examination Survey (NHANES; n = 4,591), we employed multivariate regression analysis to gauge the connection between adult serum chloride concentrations and the risk of hypertension occurring. …”
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Investigation of the antioxidant status and the number of double-stranded DNA breaks in models of brain tumor lesion by metastases of non-small cell lung cancer in vivo by E. V. Zaikina, I. A. Alliluev, Yu. N. Lazutin, Yu. V. Przhedetskiy, Yu. S. Shatova, M. A. Engibaryan, E. F. Komarova, D. A. Kharagezov, A. V. Galina, A. A. Kiblitskaya, M. V. Mindar, L. Z. Kurbanova

“…Growth rates were controlled and intracranial xenografts were visualized using a high-resolution micro-CT system. …”
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Relationship between latent left ventricular contractile dysfunction and signs of immune inflammation in patients with COVID-19 pneumonia by N. E. Shirokov, E. I. Yaroslavskaya, D. V. Krinochkin, N. A. Musikhina, T. I. Petelina, N. A. Osokina

“…To investigate the relationship between echocardiographic parameters and laboratory immune inflammation signs in patients after coronavirus disease 2019 (COVID-19) pneumonia depending on the left ventricular (LV) involvement according to speckle tracking echocardiography (STE).Material and methods. The study included 216 patients (men, 51,1%, mean age, 50,1±11,1 years). …”
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A High-Throughput, Three-Dimensional Multiple Myeloma Model Recapitulating Tumor-Stroma Interactions for CAR-Immune Cell-Mediated Cytotoxicity Assay by Luanpitpong S, Janan M, Poohadsuan J, Rodboon N, Samart P, Rungarunlert S, Issaragrisil S

“…Immune cell infiltration was visualized under a fluorescence microscope by using multiple fluorescent dyes.Results: We first showed that luciferase assay provides a relatively simple and robust means to specifically monitor Luc-labeled tumor cell growth in a coculture system, allowing the high-throughput assessment of CAR-immune cytotoxicity. …”
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Isolated Transpupillary Photodynamic Therapy in Local Treatment of Choroidal Melanoma by I. E. Panova, E. V. Boiko, E. V. Samkovich, V. G. Gvazav

“…Objective: To evaluate the long-term results of local application of transpupillary photodynamic therapy (PDT) with chlorine photosensitizer in isolated organ-preserving treatment of uveal melanoma (UM) and to determine predictors of its effectiveness.Patients and methods. Retrospective analysis of transpupillary PDT efficacy in 38 patients (38 eyes) diagnosed with choroidal melanoma (CM) treated between 2016 and 2024. …”
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Changes in the Relationship Between Gray Matter, Functional Parameters, and Quality of Life in Patients with a Post-Stroke Spastic Upper Limb After Single-Event Multilevel Surgery:... by Patricia Hurtado-Olmo, Pedro Hernández-Cortés, Ángela González-Santos, Lourdes Zuñiga-Gómez, Laura Del Olmo-Iruela, Andrés Catena

“…The functional parameters were analyzed with Fugl-Meyer, Zancolli, Keenan, House, Ashworth, pain visual analogue, and hospital anxiety and depression scales. …”
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USE OF METHOTREXATE IN PATIENTS WITH CALCIUM PYROPHOSPHATE CRYSTAL DEPOSITION DISEASE by M. S. Eliseev, S. A. Vladimirov, E. L. Nasonov

“…Objective: to compare the efficacy of methotrexate (MTX) and colchicine in patients with chronic arthritis in calcium pyrophosphate crystal deposition disease (CPPDD).Subjects and methods. Data from a controlled prospective cross-sectional study of 10 patients (8 women and 2 men) with chronic arthritis in CPPDD are presented. …”
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