Gender Influence on Bimekizumab Response in Patients with Psoriasis: Results of a Real-World Multicenter Retrospective Study—IL PSO (Italian Landscape PSOriasis) by Helena Gioacchini, Agnese Rossi, Maria Esposito, Emanuele Vagnozzi, Maria Concetta Fargnoli, Paolo Gisondi, Francesco Bellinato, Chiara Assorgi, Pina Brianti, Santo Raffaele Mercuri, Martina Burlando, Emanuele Cozzani, Giovanna Brunasso, Stefano Caccavale, Anna Balato, Giacomo Caldarola, Clara De Simone, Elena Campione, Alessandro Giunta, Francesco Tonon, Marina Venturini, Carlo Giovanni Carrera, Angelo Valerio Marzano, Andrea Carugno, Paolo Sena, Antonio Costanzo, Alessandra Narcisi, Francesco Cusano, Paolo Dapavo, Pietro Quaglino, Annunziata Dattola, Antonio Giovanni Richetta, Francesca Gaiani, Piergiorgio Malagoli, Matteo Megna, Luca Potestio, Edoardo Mortato, Francesco Loconsole, Francesca Romano, Andrea Faragalli, Rosaria Gesuita, Tommaso Bianchelli, Federico Diotallevi, Diego Orsini, Anna Campanati

“…Notably, no studies have specifically investigated bimekizumab, a humanized, full-length IgG1 monoclonal antibody that acts as a dual inhibitor of interleukin (IL)-17A and IL-17F. Methods This was a cross-sectional, observational, retrospective, multicenter analysis. …”
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Photothermal‐Responsive Soluble Microneedle Patches for Meibomian Gland Dysfunction Therapy by Fei Yu, Xuan Zhao, Qian Wang, Yifei Niu, Peng Xiao, Jinze Zhang, Keyi Fei, Yuancong Huang, Liu Liu, Po‐Han Fang, Xinyue Du, Weihua Li, Dalian He, Tingting Zhang, Saiqun Li, Jin Yuan

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Machine learning discrimination of Gleason scores below GG3 and above GG4 for HSPC patients diagnosis by Bingyu Zhu, Longguo Dai, Huijian Wang, Kun Zhang, Chongjian Zhang, Yang Wang, Feiyu Yin, Ji Li, Enfa Ning, Qilin Wang, Libo Yang, Hong Yang, Ruiqian Li, Jun Li, Chen Hu, Hongyi Wu, Haiyang Jiang, Yu Bai

“…Among the ensemble learning methods, RF, XGBoost, and Adaboost performed the best. …”
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Effects of Varying Text Message Length and Driving Speed on the Disruptive Effects of Texting on Driving Simulator Performance: Differential Effects on Eye Glance Measures by Rimzim Taneja, Kawther Alali, Mohammed, Ki-Jana Malone, Brandon Buchanon, Ashley Blanchette, Dung Ho, Doreen Head, Randall Commissaris

“…Eye glances off the roadway are a measure of the visual distraction associated with texting while driving. …”
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Factors influencing the course of post-COVID-19-related symptoms: A bidirectional cohort study among employees in health and welfare services in Germany by Steinke, Lara, Peters, Claudia, Nienhaus, Albert, Bethge, Matthias, Koch, Peter

“…Objective: The aim of this study was to determine the prevalence and trajectory of persistent symptoms following COVID-19 and to investigate factors influencing these among employees in the health and welfare services in Germany.Methods: This exploratory, mixed retro- and prospective cohort study using paper-and-pencil questionnaires was conducted among insured persons of the German Social Accident Insurance Institution for the health and welfare services with a SARS-CoV-2 infection in 2020. …”
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Comparison of Cemented Bipolar Hemiarthroplasty versus Proximal Femoral Nail Antirotation in Patients with Unstable Intertrochanteric Femur Fractures: A Prospective Interventional... by Aditya Kumar Singh, Akshat Mittal, Manvendra Singh Rawat, Sanjay Dalakoti, Anil Kumar Joshi, Pavneesh Kumar Lohan, Chandra Shekhar, Indrajit Das Bhoumik

“…Outcomes assessed included Harris Hip Score (HHS), pain using the Visual Analogue Scale (VAS), operative time, blood loss, time to weight-bearing, hospital stay and complications. …”
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Assessing the Use of BotulinumtoxinA for Hyperactive Urinary Tract Dysfunction a Decade After Approval: General Versus Local Anesthesia for BotulinumtoxinA Detrusor Injection by Heinrich Schulte-Baukloh, Apostolos Apostolidis, Catarina Weiss, Thorsten Schlomm, Sarah Weinberger, Dirk Höppner, Kathrin Haberecht, Carsten Waskow, Hendrik Borgmann, Jörg Neymeyer, Bernhard Ralla

“…We examined the level of anxiety and pain experienced by patients who wanted to have the procedure performed under LA or general anesthesia (GA). <b>Material and Methods</b>: Patients scheduled for OnabotA DI were able to choose the anesthesia procedure (LA or GA). …”
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Clinical characteristics and surgical treatment comparison of multisegmental spinal tuberculosis: a retrospective analysis by Zongqiang Yang, Zongqiang Yang, Zhangui Gu, Zhangui Gu, Qiang Liu, Qiang Liu, Long Ma, Le Fei, Le Fei, Ningkui Niu, Ningkui Niu, Jiandang Shi

“…BackgroundTo analyze the therapeutic efficacy of intervertebral surgery in the treatment of multisegmental spinal tuberculosis (MSTB) by evaluating its clinical outcomes and perioperative indicators, thereby providing evidence-based insights to optimize surgical strategies and improve clinical decision-making.MethodsThis retrospective cohort study analyzed 134 MSTB patients treated at our hospital between January 2000 and June 2022. …”
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Prediction of solid pseudopapillary tumor invasiveness of the pancreas based on multiphase contrast-enhanced CT radiomics nomogram by Dabin Ren, Liqiu Liu, Aiyun Sun, Yuguo Wei, Tingfan Wu, Yongtao Wang, Xiaxia He, Zishan Liu, Jie Zhu, Guoyu Wang

“…A radiomics nomogram was subsequently constructed and visualized by combining traditional CT independent predictors and radiomics signature. …”
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Effect of Traditional Chinese Medicine collapse stains combined with western medicine in treating acute herpes zoster (中药溻渍联合西医治疗急性期带状疱疹的疗效观察)... by YAO Meiyu (姚美玉), SUN Mingli (孙明丽), TANG Ling (唐玲), ZHOU Jie (周洁), CHEN Hong (陈宏)

“…The pain degree measured by Visual Analogue Scale (VAS) and treatment efficacy of the two groups were compared. …”
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Prevalence of falls and associations with family functioning among community-dwelling older adults in Guangzhou, China by Si-Yu Sun, Zhi-Wei Wang, Zhi-Li Peng, Le-Xin Yuan, Wen-Hao Yang, Wen-Jian Zhang, Jia-Min Chen, Wei-Quan Lin, Wei Zhu, Wei Zhu

“…Consequently, this study aims to investigate the prevalence and influencing factors of falls among community-dwelling older adults in Guangzhou, China, with a particular emphasis on the impact of family functioning.MethodsWe used a multi-stage stratified cluster random sampling technique to successfully survey 2,399 individuals aged 65 and above across 11 districts in Guangzhou City. …”
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Efficacy of topical Raphanus sativus seed powder mixed with honey versus hydroquinone 4 % cream in the treatment of melasma – A randomized controlled trial by Arshan Horti, Shaikh Nisar Ahmed Abbas, Shavana Fathima, Mamadapur Saba Abdul Razzaq, Arsheya Parvez Mistry, Farooqui Shazia Parveen, Nazim Husain

“…Secondary measures examined subjective nuances using a 100 mm visual analogue scale (VAS) and recorded the dermatology life quality index (DLQI) at baseline and the conclusion of the study. …”
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Biomechanical and clinical differences in muscle tone, stiffness, range of motion, and pain perception in children with cerebral palsy: a cross-sectional study by Ramón González-Matilla, Ramón González-Matilla, Ramón González-Matilla, Vanesa Abuín-Porras, Isabel Mínguez-Esteban, Alberto M. Heredia-Rizo, Alberto M. Heredia-Rizo, Alberto M. Heredia-Rizo

“…ROM was assessed by goniometry, and pain perception was evaluated using the Visual Analog Scale during a Straight Leg Raise (SLR) test. …”
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Rheumatoid arthritis and psoriatic arthritis: is the disease impact different? A large matching study at diagnosis and after 1 year of treatment by Annette H M van der Helm-van Mil, Pascal H P de Jong, Sytske Anne Bergstra, Elise van Mulligen, Ilja Tchetverikov, Jolanda J Luime, Marijn Vis, Marc R Kok, Maikel van Oosterhout, Jos H van der Kaap, Selinde V J Snoeck Henkemans, Anne-Fleur van den Biggelaar

“…Therefore, we aimed to determine the difference in disease impact between matched RA and PsA patients at diagnosis and after 1 year in two different regions.Methods RA patients from the treatment in the Rotterdam Early Arthritis CoHort trial (tREACH), PsA patients from the Dutch southwest Early PsA cohoRt (DEPAR) and RA and PsA patients from the Leiden Early Arthritis Clinic (EAC) were included. …”
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Efficacy and safety of photobiomodulation combined with oral cryotherapy on oral mucosa pain in patients with burning mouth syndrome: a multi-institutional, randomized, controlled... by Chenghui Lu, Xuan Zhou, Chenglong Yang, Xinxiang Jiang, Xin Li, Zefan Huang, Qing Du, Guoyao Tang

“…The coprimary outcome measures were changes in visual analogue scale (VAS) scores and the overall response rate between baseline and 7 weeks of treatment. …”
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The effect of supplementation with type I and type III collagen peptide and type II hydrolyzed collagen on pain, quality of life and physical function in patients with meniscopathy... by Ahmet Serhat Genç, Ali Kerim Yılmaz, Berna Anıl, Esra Korkmaz Salkılıç, Enes Akdemir, Berna Güzel, Ahmet Mor, Hacı Ahmet Yarar, Nizamettin Güzel, Lokman Kehribar

“…This study aimed to evaluate the effects of Naturagen® 4 Joint product containing type I, II, and III collagen on pain, quality of life, and physical functions in patients with meniscopathy. Methods This randomized, double-blind, placebo-controlled clinical study included 32 patients (collagen = 17 and placebo = 15) with meniscopathy. …”
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NETs activate the GAS6-AXL-NLRP3 axis in macrophages to drive morphine tolerance by Qingyan Tian, Haiyue Guo, Mengyao Zhang, Kunmao Jiang, Fan Hu, Yan Xu, Li Wan, Xiaokai Zhou, Yinbing Pan, Wentao Liu, Chun-Yi Jiang

“…Confocal laser scanning microscopy was utilized to visualize NETs in the dorsal root ganglion (DRG) and in cells. …”
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Meta-analyses of the effects of high-intensity interval training in elite athletes — part II: relationships between the mean effects on various performance measures by Hans-Peter Wiesinger, Hans-Peter Wiesinger, Hans-Peter Wiesinger, Will G. Hopkins, Nils Haller, Nils Haller, Julia Blumkaitis, Tilmann Strepp, Thomas Leonhard Stöggl, Thomas Leonhard Stöggl

“…Here, we extend the analyses to relationships between mean changes of these measures and consider implications for understanding and improving HIIT that were not apparent in the previous analyses.MethodsThe data were mean changes from HIIT with highly trained endurance and elite other (mainly team sport) athletes in studies where two or more measures or predictors of performance were available. …”
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Effects of plant active substances in rheumatoid arthritis—a systematic review and network meta-analysis by Qiuwei Peng, Jian Wang, Kesong Li, Congming Xia, Chuanhui Yao, Qiuyan Guo, Xun Gong, Xiaopo Tang, Quan Jiang

“…The main focus was on assessing primary outcomes, including the Visual Analogue Scale (VAS), inflammatory markers, Swollen Joint Count (SJC), Tender Joint Count (TJC), and Disease Activity Score on 28 joints (DAS28). …”
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The burden of refraction disorders in 204 countries and territories from 1990 to 2021: A systematic analysis from the global burden of disease 2021 by Yunhan Shen, Linyan Wang, Yuxin Cui, Bangxun Mao, Grace Loy Ming Hooi, Oluwatobi Idowu, Juan Ye, Tiansheng Zhu

“…Background: Refraction disorders are common eye conditions that cause blurred vision and, if left uncorrected, remain a leading cause of moderate to severe visual impairment worldwide. Despite this, a comprehensive assessment of the associated burden is lacking. …”
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