The association and impact of radiographic, pathological emphysema and spirometric airway obstruction on patients with resectable lung adenocarcinoma by Yixiao Zhang, Lu Lang, Xiaojuan Guo, Kewu Huang, Jiawen Yi, Yuan Yuan, Min Zhu, Shu Zhang, Bin Hu, Xue Li, Yuhui Zhang

“…CT-defined emphysema at baseline was assessed visually and quantitatively, pathological emphysema was reviewed on postoperative specimen. …”
Get full text

Evaluating Dental Pain in Diverse Conditions: Findings From Short-Form McGill Pain Questionnaire Study by Jin Wang, Yin-Fei Pu, Hong-Tao Chen, Xiang-Song Bai, Xue Yang, Ai-Ping Ji, Jie Bai

“…Pain was assessed using the SF-MPQ, which includes the Visual Analogue Scale (VAS), Present Pain Intensity (PPI), and Pain Rating Index (PRI). …”
Get full text

Epidemiological trends and forecasting of tuberculosis burden in the Gulf Cooperation Council countries: Evidence from global burden of disease 1990–2021 by Akashanand, Shailesh Kumar Samal, Shilpa Gaidhane, Diptismita Jena, R. Roopashree, Mandeep Kaur, Deepak Nathiya, Aryantika Sharma, G.V. Siva Prasad, Aashna Sinha, Lara Jain, Vaibhav Jaiswal, Muhammed Shabil, Ganesh Bushi, Sanjit Sah, Ghaya Alqurainees, Jawaher Alotaibi, Maha A. Alshiekheid, Amal A. Sabour, Nawal A. Al Kaabi, Hayam A. Alrasheed, Muhammad A. Halwani, Zainab H. Almansour, Fatimah S. Aljebaly, Mubarak Alfaresi, Ali A. Rabaan

“…Understanding trends in TB burden in these countries is essential for guiding public health strategies. Methods: We analyzed TB trends in GCC countries from 1990 to 2021 using data from the Global Burden of Disease (GBD) study. …”
Get full text

Comparative evaluation of three polymerase chain reaction primer sets for accurate molecular detection of Trypanosoma lewisi in wild rodents in Indonesia by Aditya Yudhana, Gusti Ayu Illiyin Putri Santosa, April Hari Wardhana, Frenky Laksana Putra, Ryanka Edila, Dyah Haryuningtyas Sawitri, Ratih Novita Praja, Muhammad Aqil Kurnianto, Aldi Gusnizar Rizaldy Tanjung, Marc Desquesnes, Makoto Matsubayashi

“…DNA amplification products were visualized using agarose gel electrophoresis. Diagnostic performance was evaluated based on sensitivity and specificity calculations using microscopy as the reference standard. …”
Get full text

Randomised controlled trial of topical combination therapy chlorhexidine 0.2% and natamycin 5% versus topical natamycin 5% alone for fungal keratitis in East Africa: study protocol... by David Macleod, Einoti Matayan, William Makupa, Jeremy John Hoffman, Simon Arunga, Francis Orishaba, Abel Ebong, Reena Yadav, Astrid Leck, Muna Elisante, Tara Mtuy, Sandip Das Sanyam, Victor H Hu, Matthew J Burton

“…The primary outcome is best spectacle corrected visual acuity (BSCVA) at three months. Primary analysis (intention-to-treat) will be by linear regression, with treatment arm and baseline BSCVA pre-specified covariates. …”
Get full text

SMART accelerates rate of cognitive gains in service members with mTBI and PTSD by Erin Venza, Jeffrey S. Spence, Jennifer Zientz, Cole Devlin, Jason Bailie, Jason Bailie, Jason Bailie, Andrew Darr, Andrew Darr, Andrew Darr, Ida Babakhanyan, Ida Babakhanyan, Ida Babakhanyan, Sandra Bond Chapman

“…The study also examined the relationship between PTSD symptom severity and cognitive outcomes.MethodsA total of 148 ADSMs with mTBI and persistent cognitive complaints were randomized to receive either SMART (20 h over 4 weeks) or SCORE (60 h over 6 weeks). …”
Get full text

Test-retest reliability of diffusion kurtosis imaging metrics in the healthy adult brain by Liu-Yang Wu, Yao Xu, Lan-Lan Chen, Wen-Rui Yang, Yan Li, Song-An Shang, Xian-Fu Luo, Wei Xia, Jing Xia, Hong-Ying Zhang

“…Although the DKI reliability of GM regions varied, the default mode and visual areas consistently demonstrated the highest ICC reliability for a series of kurtosis-related metrics. …”
Get full text

Investigation of early-stage cardiovascular-kidney-metabolic syndrome on retinal structure and function evaluated by optical coherence tomography angiography by Yunyi Liang, Congbi Liang, Jianping Yang, Wanhua Li, Runyi Liang, Kun Li, Jingfeng Zhang, Peiqiong Lao, Junhua Zhu, Lin An, Zhaohao Liang, Chubin Ou

“…BackgroundThe retina serves as a non-invasive window to visualize systemic health, with optical coherence tomography angiography (OCTA) enabling simultaneous assessment of retinal structural thickness and vascular density. …”
Get full text

Non-inferiority comparison of medical glue and hook-wire for preoperative localization of multiple pulmonary nodules by Zexin Xie, Zexin Xie, Ran Ma, Ran Ma, Tao Gao, Tao Gao, Jingsong Liu, Jingsong Liu, Kewei Zhang, Kewei Zhang, Jun Li, Jun Li, Xiaotong Zhou, Xiaotong Zhou, Hao Zhang, Hao Zhang

“…However, precisely localizing deep-seated or poorly visualized nodules remains a prominent challenge. This study aims to compare the effectiveness and safety of medical glue vs. hook-wire in the CT-guided localization of multiple pulmonary nodules.MethodsA prospective cohort of patients scheduled for CT-guided localization of multiple pulmonary nodules between February 2024 and August 2024 was enrolled. …”
Get full text

“Koshimagari Exercise” for Adult Spinal Deformity in Older Adults: Assessment of Home-Based Exercise Outcomes in a Prospective Multicenter Study by Hidetomi Terai, Shinji Takahashi, Masatoshi Hoshino, Hiroshi Taniwaki, Koji Tamai, Toshimitsu Ohmine, Tamotsu Nakatsuchi, Goya Shinbashi, Masatoshi Teraguchi, Masakazu Minetama, Kei Watanabe, Naritoshi Sato, Takuya Kitamura, Masaru Kanda, Tadao Tsujio, Yuichi Takeuchi, Tatsuki Mizouchi, Katsuhito Ishizu, Toshihito Ebina, Yasunari Muraoka, Tomonori Sodeyama, Hiroshi Mikami, Yuji Kasukawa, Takahiko Hyakumachi, Kazuhiro Ishida, Kazufumi Miyagishima, Yosuke Oishi, Kiyonori Yo, Ryota Kimura, Hiromichi Sato, Keiji Nagata, Yu Yamato, Ko Matsudaira, Naohisa Miyakoshi, Yukihiro Matsuyama, Hirotaka Haro, Hiroshi Hashizume, Hiroshi Yamada, Takashi Kaito, Project Committee of the Japanese Society for Spine Surgery and Related Research (JSSR)

“…This study aimed to investigate the impact of “Koshimagari exercise,” a specific home-based exercise regimen designed for patients with ASD, and to evaluate its effects on clinical outcomes in older adults. Methods: A total of 144 participants aged 50-80 years with chronic low back pain (LBP) due to spinal deformities were included in this multicenter prospective study. …”
Get full text

Primary deltoid ligament repair versus trans-syndesmotic fixation for acute bimalleolar equivalent ankle fractures: A meta-analysis of comparative studies by Osama Z. Alzobi, Hammam Kayali, Loay Salman, Mohamed Kenawey, Ashraf Hantouly, Motasem Salameh, Bashir Zikria, Pieter D'Hooghe, Vinod Panchbhavi, Mohamed Mekhaimar, Salah AlBurdeni, Jasim Alsaei

“…They likewise reported comparable visual analog scale for pain (MD = −0.03; 95 % CI, −0.39-0.34; I2 = 0 %; P = 0.8), and lower complication rates (RR, 0.26; 95 % CI, 0.10–0.69; I2 = 0 %; P = 0.01). …”
Get full text

Psychological correlates of COVID-19 vaccine attitudes among medical professionals: An exploratory data analysis by Aldo SITIBONDO, Aanuoluwapo AFOLABI, Jamel HAJJI, Abdulmohsen Mohammed Abdullah ALKHULAYFI, Izaddin Ahmad AZIZ, Zane Asher GREEN, Francesca BRUNO, Martina BARBERA, Murat YLDIRIM

“…Group comparisons of emotional responses were visualized using bar plots. Results: Most participants were fully vaccinated. …”
Get full text

Differentiating between adrenocortical carcinoma and pheochromocytoma by a CT-based radiomics model: a multicenter retrospective study by Yinyao Chao, Hongzhang Zhu, Wenyi Yang, Haohua Yao, Nan Ma, Xianda Chen, Jing Zhao, Huali Ma, Zhenhua Liu, Hui Han, Zhuowei Liu, Kai Yao, Yiyao Li, Peng Wu, Jingtong Zhang, Bin Li, Shengjie Guo

“…This study aims to differentiate between large (≥ 4 cm) ACC and PHEO with radiomics features based on contrast-enhanced CT. Methods In this retrospective study, 158 patients who received pathological diagnoses of ACC or PHEO between January 2011 and September 2023 were enrolled from three institutions. …”
Get full text

Exome sequencing revealed a novel homozygous variant in TRMT61 A in a multiplex family with atypical Cornelia de Lange Syndrome from Rwanda by Esther Uwibambe, Abdoulaye Yalcouyé, Elvis Twumasi Aboagye, Lettilia Xhakaza, Kalinka Popel, Norbert Dukuze, Thashi Bharadwaj, Carmen de Kock, Isabelle Schrauwen, Suzanne M. Leal, Leon Mutesa, Ambroise Wonkam

“…We performed a molecular characterization of CdLS in a multiplex Rwandan family. Methods After a clinical evaluation of two affected siblings, DNA isolated from peripheral whole blood of the affected patients and their parents underwent Exome Sequencing (ES). …”
Get full text

De novo variant in GUCY2D gene causing atypical cone-rod dystrophy in a consanguineous family and literature review by Xin-He Fang, Fa-Yong Ke, Wen-Qing Zou, De-Jun Zhu, Mei-Jiao Ma, Yuan-Yuan Lian, Xue-Li Wu, Rui-Hua Wei, Xun-Lun Sheng

“…AIM: To analyze the pathogenicity and clinical features of patients in a consanguineous cone-rod dystrophy (CRD) family due to heterozygous variants in the GUCY2D gene. METHODS: Whole exome sequencing was used to screen for pathogenic genes and candidate pathogenic variants were obtained by bioinformatics analysis. …”
Get full text

Feasibility of relaxation along a fictitious field in the 2nd rotating frame (TRAFF2) mapping in the human myocardium at 3 T by Joao Tourais, Joao Tourais, Joao Tourais, Maša Božić-Iven, Maša Božić-Iven, Maša Božić-Iven, Yidong Zhao, Qian Tao, Iain Pierce, Iain Pierce, Christian Nitsche, Christian Nitsche, George D. Thornton, George D. Thornton, Lothar R. Schad, Lothar R. Schad, Thomas A. Treibel, Thomas A. Treibel, Sebastian Weingärtner, Mehmet Akçakaya, Mehmet Akçakaya

“…PurposeEvaluate the feasibility of quantification of Relaxation Along a Fictitious Field in the 2nd rotating frame (RAFF2) relaxation times in the human myocardium at 3 T.MethodsTRAFF2 mapping was performed using a breath-held ECG-gated acquisition of five images: one without preparation, three preceded by RAFF2 trains of varying duration, and one preceded by a saturation prepulse. …”
Get full text

Platelet-rich plasma therapy for knee osteoarthritis: Insights from real-world clinical data in Japan by Yoshitomo Saita, Yohei Kobayashi, Sayuri Uchino, Hirofumi Nishio, Takanori Wakayama, Shin Fukusato, Yasumasa Momoi, Ryosuke Nakajima, Nanako Yamamoto, Shinnosuke Hada, Haruka Kaneko, Muneaki Ishijima

“…The eligibility criteria included chronic knee pain unresponsive to conservative treatment for KOA. Visual Analog Scale (VAS) for knee pain were collected at baseline and 3 and 6 months post-treatment. …”
Get full text

Neuroimaging differences between chronic migraine with and without medication overuse headache: a 7 Tesla multimodal MRI study by Yin Sun, Longteng Ma, Song Wang, Caohui Duan, Xinyu Wang, Xiangbing Bian, Shuqing Wang, Deqi Zhai, Siyuan Xie, Shuhua Zhang, Yingyuan Liu, Xiaoxue Lin, Ruobing Wang, Xiu Liu, Shengyuan Yu, Xin Lou, Zhao Dong

“…Conclusion Compared to CM − MOH patients, those with MOH exhibit distinct patterns of gray matter volume reduction in regions associated with memory and visual processing, accompanied by significant white matter disruption. …”
Get full text

Comparison of low-pressure and standard-pressure pneumoperitoneum laparoscopic cholecystectomy in patients with cardiopulmonary comorbidities: a double blinded randomized clinical... by Feng Tian, Xiaowei Sun, Yang Yu, Ning Zhang, Tao Hong, Lu Liang, Bihui Yao, Lei Song, Changhong Pei, Yu Wang, Wenlong Lu, Qiang Qu, Junchao Guo, Taiping Zhang, Xiaodong He

“…This study aimed to explore the feasibility and pulmonary effects of LPLC in patients with cardiopulmonary comorbidities. Methods This was a multicenter, parallel, double-blind, randomized controlled trial. …”
Get full text

Short-term use of ceftriaxone sodium leads to intestinal barrier disruption and ultrastructural changes of kidney in SD rats by Wenli Zou, Yueming Liu, Wei Zhang, Bo Lin, Wei Shen, Yiwen Li, Qiang He, Juan Jin

“…The aim of this study was to evaluate and visualize the impact of antibiotics on colonic mucus and the microbial community, and to assess whether intestinal dysbacteriosis is involved in the pathogenesis and progression of extraintestinal diseases in vivo.Materials and Methods Twenty-one SD rats were randomly assigned into three groups followed by different experimental treatments. …”
Get full text