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9481
Versatile clinical application of radial artery perforator flap for hand and wrist reconstruction
Published 2023-01-01“…The aim of this study was to summarize and analyze the results of the treatment of patients with upper extremity soft tissue defects caused by trauma, infection, burn, or tumor removal, which were re-constructed with RAPF. Methods. This retrospective study included 20 consecutive patients with skin and soft tissue defects of the hand and wrist, treated at the University Clinical Center of Vojvodina from 2012 to 2022. …”
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9482
Modern Trends in the Digitalization of Higher Physical Education in China
Published 2025-03-01“…The article concludes by recommending a blended learning model for HPE, combining online theoretical instruction with in-person practical training to balance the benefits of both digital and traditional methods. It suggests that investments in technology infrastructure, ongoing research, and collaborations between educational institutions and government agencies are crucial to addressing these challenges and ensuring the successful digital transformation of HPE. …”
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9483
One size doesn’t fit all: regional dynamics in pediatric emergency visits during the SARS-CoV-2 pandemic
Published 2025-08-01“…This study aimed to analyze changes in pediatric ED catchment areas over time across three Swiss centers and explore implications for future healthcare crises.MethodsWe conducted a retrospective, longitudinal cohort study at three tertiary pediatric EDs in Zurich, Bellinzona, and Geneva, covering different language regions. …”
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9484
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9485
Clinician Perspectives of a Magnetic Resonance Imaging–Based 3D Volumetric Analysis Tool for Neurofibromatosis Type 2–Related Schwannomatosis: Qualitative Pilot Study
Published 2025-07-01“…ObjectiveThe objective of the study was to survey and interview clinicians treating neurofibromatosis type 2–related schwannomatosis to understand their views on current 2D analysis and to gather insights for the design of an artificial intelligence–driven 3D volumetric analysis tool. MethodsInterviews examined for the following themes: (1) shortcomings of the currently used linear analysis, (2) utility of 3D visualizations, (3) features of an interactive 3D modeling software, and (4) lack of a gold standard to assess the accuracy of 3D volumetric analysis. …”
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9486
Research hotspots and trends on NF-κB in cognitive impairment: a bibliometric analysis
Published 2024-12-01“…However, no bibliometric analysis regarding the relationship between CI and NF-κB has been reported.MethodsA bibliometric analysis regarding NF-κB and CI from 1 January 2008 to 12 December 2023 was conducted in the Science Citation Index-Expanded of the Web of Science Core Collection. …”
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9487
Automatic segmentation model and machine learning model grounded in ultrasound radiomics for distinguishing between low malignant risk and intermediate-high malignant risk of adnex...
Published 2025-01-01“…Abstract Objective To develop an automatic segmentation model to delineate the adnexal masses and construct a machine learning model to differentiate between low malignant risk and intermediate-high malignant risk of adnexal masses based on ovarian-adnexal reporting and data system (O-RADS). Methods A total of 663 ultrasound images of adnexal mass were collected and divided into two sets according to experienced radiologists: a low malignant risk set (n = 446) and an intermediate-high malignant risk set (n = 217). …”
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9488
Clinical experience of cone-beam computed tomography in interventional neuroradiology
Published 2024-06-01“…Objective ‒ to analyze the experience of using cone-beam computed tomography (CBCT) angiography during diagnostic and interventional procedures in the SO «Scientific-Practical Center of Endovascular Neuroradiology NAMS of Ukraine». Materials and methods. Informed consent was obtained from each patient (parent or guardian) enrolled in the study and the study protocol conforms to the ethical guidelines of the Declaration of Helsinki as reflected in a priori approval by the Institutional Ethical Review Board (Institution's Human Research Committee). …”
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9489
A bioinformatic analysis to systematically unveil shared pathways and molecular mechanisms underlying monkeypox and its predominant neurological manifestations
Published 2025-07-01“…This study aimed to explore the genetic underpinnings of MPOX-related neurological manifestations, including headache, myalgia, fatigue, and photophobia, using advanced bioinformatics tools.MethodsData were sourced from the GeneCards database, which is an integrated database of human genes. …”
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9490
Novel computational One-Health analysis of fibrinogen-binding protein A in Streptococcus agalactiae Isolated from fish and human cases
Published 2025-05-01“…This study aimed to conduct a novel computational One Health analysis comparing the FbsA protein from fish- and human-derived GBS strains to elucidate their structural and functional similarities and explore their interaction with human fibrinogen (Fg). Materials and Methods: Amino acid sequences of FbsA from fish and human GBS isolates were retrieved from the National Center for Biotechnology Information database. …”
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9491
Telomeric RNA quadruplexes as targets for cancer prevention: The therapeutic potential of agonodepsides
Published 2025-03-01“…Agonodepsides A and B, two promising fungal metabolites, were chosen to investigate this exciting possibility. Methods: Agonodepside A and B were initially screened for drug likeness employing SwissAdme. …”
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9492
Utility of a Large Series of B‐Cell Precursor Acute Lymphoblastic Leukemia Cell Lines as a Model System
Published 2025-03-01“…Cancer cell lines are powerful research tools, and thus, we built a larger series of BCP‐ALL cell lines and performed RNA‐seq analysis to confirm their utility as a model system. Methods We performed RNA‐seq in a total of 94 BCP‐ALL cell lines, including 80 cell lines with 8 representative types of translocations. …”
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9493
The alteration of the sensorimotor network in trigeminal neuralgia after microvascular decompression surgery: a follow-up study using independent component analysis
Published 2025-08-01“…Resting-state functional magnetic resonance imaging (rs-fMRI) has been extensively applied in studies of TN, uncovering alterations in brain activity, functional connectivity, cortical thickness and neural networks.MethodsIndependent component analysis (ICA) presents a powerful alternative for analyzing fMRI data, offering several advantages over traditional region of interests (ROIs) approaches. …”
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9494
Delta large-channel endoscopy versus unilateral biportal endoscopy decompressive laminectomy for lumbar spinal stenosis: a prospective randomized controlled trial
Published 2025-01-01“…This randomized controlled trial aims to compare their perioperative outcomes, focusing on postoperative recovery and complications over time. Methods In total, 101 participants were randomly assigned to Delta large-channel endoscopy group (n = 50) or UBE group (n = 51). …”
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9495
Optimizing Contrast‐Enhanced Magnetic Resonance Neurography of the Brachial Plexus With Delayed Scanning
Published 2025-04-01“…Methods Fifteen patients underwent brachial plexus imaging using the 3D T2‐NerveView sequence with a scanning duration of 5 min. …”
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9496
Global trends in machine learning applications for single-cell transcriptomics research
Published 2025-08-01“…Methods Using 3,307 publications from Web of Science Core Collection(WOSCC), we conducted bibliometric and visualization analysis through CiteSpace and VOSviewer to systematically review research trends, national/institutional contributions, keyword co-occurrence networks and co-citation relationships. …”
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9497
OUTCOMES OF 5-ALA FLIORESCECE-GUIDED SURGERY FOR HIGH GRADE G
Published 2018-05-01“…The purpose of this study was to analyze the results of 5-ALA fluorescent-guided resection in patients with HGG by comparing neuroimaging characteristics, intraoperative parameters and clinical outcomes. Material and methods. The study included 48 patients (30 men and 18 women) aged 35 to 76 years (mean age 47.3 ± 8.4 years) with newly diagnosed HGG. …”
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9498
Analyzing pathogenic variants in mismatch repair genes: personalized prevention strategies for lynch syndrome in Chinese families
Published 2025-03-01“…BackgroundThis study aimed to analyze the pathogenic variants in one family with colorectal cancer and another with endometrial cancer and provide appropriate personalized prevention strategies for carriers of these genetic mutations.MethodsOne proband with colorectal cancer and another with endometrial cancer and their family members were enrolled in this study. …”
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9499
Fluorescence by 5-aminolevulinic acid-induced protoporphyrin IX varies in tumor and normal tissues during robot-assisted partial nephrectomy for renal cell carcinoma
Published 2025-06-01“…Although effective in other malignancies, its utility in renal tumors is not well established. Methods Between May 2016 and August 2017, 19 patients underwent RAPN using photodynamic diagnosis (PDD) at our institution with the da Vinci Surgical System Si®. …”
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9500
Enhanced diagnostic precision of colorectal sessile lesions with blue laser imaging and JNET classification: a multicenter retrospective study in Chinese cohorts
Published 2025-05-01“…However, its diagnostic performance in Chinese populations and the impact of endoscopist experience remain underexplored.MethodsIn this multicenter, retrospective study, 131 colorectal sessile lesions were enrolled. …”
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