Exploring the role of hyperreflective walls as a biomarker for the management of cystoid macular edema by Zhang-Rong Yang, Chang Li, Dong-Jun Xing, Gao-Xu Wei, Ce-Ce Zhao, Miao Zhou, Xiao-Han Ma, Yi Zhao, Shu Yang, Rong-Guo Yu, Zhi-Qing Li

“…AIM: To investigate the prevalence and clinical implications of hyperreflective walls (HRW) in foveal cystoid spaces in patients with cystoid macular edema (CME) caused by retinal diseases and noninfectious uveitis (NIU). METHODS: This retrospective cross-sectional study included 443 eyes with CME secondary to diabetic macular edema (DME), retinal vein occlusion (RVO), retinitis pigmentosa (RP), neovascular age-related macular degeneration (nAMD), and NIU. …”
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Multidimensional outcome after endovascular or microsurgical occlusion of ruptured intracranial aneurysms – Comparative analysis of a prospective Swiss multicenter study by Vincens Kälin, Martin N. Stienen, Olivia Zindel-Geisseler, Noemi Dannecker, Yannick Rothacher, Ladina Schlosser, Julia Velz, Martina Sebök, Noemi Eggenberger, Adrien May, Philippe Bijlenga, Ursula Guerra-Lopez, Rodolfo Maduri, Daniele Starnoni, Valérie Beaud, Alessio Chiappini, Thomas Robert, Sara Bonasia, Stefania Rossi, Johannes Goldberg, Christian Fung, David Bervini, Klemens Gutbrod, Nicolai Maldaner, Severin Früh, Marc Schwind, Anna-Maria Zeitlberger, Isabel C. Hostettler, Oliver Bozinov, Peter Brugger, Menno R. Germans, Luca Regli

“…Research question: Are there significant differences in multidimensional outcomes between clipping and coiling treatments for alert aSAH patients when treatment selection is individualized? Material and methods: Within the prospective MoCA-DCI study (ClinicalTrials.gov identifier: NCT03032471), patients with a GCS of 13–15 72h post-aSAH in six neurovascular centers underwent neuropsychological (Montreal Cognitive Assessment; MoCA), neurological (National Institutes of Health Stroke Scale; NIHSS), headache (visual analog scale; VAS), disability (modified Rankin Scale; mRS) and health-related quality of life (EuroQol Five Dimensions; EQ5D) assessments within 72h, 14 days and three months after aSAH. …”
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Epidemiological trends and forecasting of tuberculosis burden in the Gulf Cooperation Council countries: Evidence from global burden of disease 1990–2021 by Akashanand, Shailesh Kumar Samal, Shilpa Gaidhane, Diptismita Jena, R. Roopashree, Mandeep Kaur, Deepak Nathiya, Aryantika Sharma, G.V. Siva Prasad, Aashna Sinha, Lara Jain, Vaibhav Jaiswal, Muhammed Shabil, Ganesh Bushi, Sanjit Sah, Ghaya Alqurainees, Jawaher Alotaibi, Maha A. Alshiekheid, Amal A. Sabour, Nawal A. Al Kaabi, Hayam A. Alrasheed, Muhammad A. Halwani, Zainab H. Almansour, Fatimah S. Aljebaly, Mubarak Alfaresi, Ali A. Rabaan

“…Understanding trends in TB burden in these countries is essential for guiding public health strategies. Methods: We analyzed TB trends in GCC countries from 1990 to 2021 using data from the Global Burden of Disease (GBD) study. …”
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The impact of aripiprazole on neurocognitive function in individuals at clinical high risk for psychosis: A comparison with olanzapine and non-antipsychotic treatment by JiaHui Zeng, Andrea Raballo, JiaYi Ye, YuQing Gao, WenJun Su, YanYan Wei, XiaoChen Tang, LiHua Xu, YeGang Hu, Dan Zhang, HuiRu Cui, YingYing Tang, XiaoHua Liu, HaiChun Liu, Tao Chen, ChunBo Li, JiJun Wang, TianHong Zhang

“…This study investigates the association between aripiprazole and olanzapine use and cognitive and clinical outcomes in CHR individuals, compared to those receiving no antipsychotic treatment. Methods A retrospective analysis was conducted on 127 participants from the Shanghai At Risk for Psychosis (SHARP) cohort, categorized into three groups: aripiprazole, olanzapine, and no antipsychotic treatment. …”
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Exploring the predictive value of serum lipids for short‐term prognosis in patients with acute‐on‐chronic liver failure by Yunfeng Fu, Kaini Wu, Sicheng Yang, Yuanping Fan, Jianhao Qiu, Qi Zhu, Yating Pan, Xiaqin Chen, Sihai Chen, Xiaodong Zhou

“…This study aimed to investigate the predictive value of serum lipids for short‐term prognosis in patients with ACLF. Methods This retrospective analysis was conducted using the clinical data of patients hospitalized for ACLF between January 2018 and December 2021. …”
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Pomalidomide in relapsed and refractory multiple myeloma: multicenter retrospective study by V. G. Potapenko, E. V. Baumert, A. A. Bobrova, R. V. Vashchenkov, N. V. Dorofeeva, K. D. Kaplanov, E. V. Karyagina, A. N. Levanov, A. S. Luchinin, S. I. Moiseev, A. V. Novitskii, A. S. Nizamutdinova, О. V. Pirogova, S. A. Povzun, М. V. Platonov, V. V. Porunova, D. А. Ptashnikov, V. V. Ryabchikova, S. Ya. Simeniv, I. А. Skorokhod, Е. А. Ukrainchenko, D. А. Chaginskaya, T. V. Shelekhova, M. N. Shirokova, A. A. Shutylev, N. V. Medvedeva

“…To evaluate efficacy, safety and optimal course of the therapy with pomalidomide in routine practice in patients with double refractory multiple myeloma.Materials and methods. Overall, 71 patients with double refractory multiple myeloma were included in the retrospective analysis. …”
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Decolonization Projects by Cornelius Ewuoso

“…International Journal of Qualitative Methods, 20, 16094069211014766. [10] Abimbola Seye 2023. …”
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Muqarada sukuk as an Investment Tool in Endowment Funds and the Possibility of its Application in Iraq an Analytical Study by Ardawan Mustafa Ismael, Abdulrrahman Ibrahim Ubaeed

“…Among the contemporary methods for investing endowments are Muqarada instruments, as they are an Islamic alternative to investment bonds in usurious banks, and the first to be used by the Jordan Islamic Bank in the eighties of the last century, and they represent common shares in the speculative capital, which is of equal value, and has a prospectus that contains all the information required by Sharia, such as knowledge of the capital and distribution of profits, and it is tradable in the stock market if it mostly represents assets and benefits. …”
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THE STATE OF HARD TISSUE OF TEMPORARY TEETH IN CHILDREN FROM ORPHANAGES AND BOARDING-SCHOOLS by O.T. Narepekha, I.S. Dubetska-Hrabous

“…The purpose of the study is to analyze the state of hard tissue of temporary teeth in children from boarding schools and orphanages for differentiated preventive and therapeutic measures. Material and methods. 440 children at the age of 3,5,7,9,12 years from boarding –schools and orphanages that formed the main group and 155 Lviv `s preschool and school children (comparison group) were examined. …”
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Prevalence, Awareness, and Factors Associated with Hypertension Among Adults in Rural Southwestern Uganda: A Baseline Survey by Kansiime G, Nuwagira E, Obwoya PS, Baluku JB, Kanyesigye M, Twesiime C, Ssebutinde P, Muhindo R, Muyingo A, Kananura K, Tusingwire PD, Atukunda EC, Kalyesubula R, Bajunirwe F, Muiru A

“…This study examines the prevalence, awareness, and associated factors of hypertension among adults in a rural community in southwestern Uganda.Methods: We conducted a baseline survey in Ngango, Mbarara district, enrolling adults aged 18– 79 years from eleven villages. …”
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N4BP3 Activates TLR4-NF-κB Pathway in Inflammatory Bowel Disease by Promoting K48-Linked IκBα Ubiquitination by Jiang W, Yin J, Han M, He W, Zhao Y, Hu J, Wang M, Wang S, Xu J, Deng C, Li J, Gong X, Shen Y

“…It is crucial to investigate whether N4BP3 regulates inflammatory bowel disease (IBD) through the TLR4 signaling pathway and to elucidate the underlying mechanisms.Methods: Lipopolysaccharides (LPS) were used to activate the TLR4 pathway in THP-1/Caco-2 cells. …”
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From Reductionist Skills to Meaningful Learning: Trust and Humility in Bedside Cardiac Assessment by Meisel JL, Navedo DD, Opole IO, Cohen GM, Bernard SA, Carmona H, Nahas AH, Eiduson CM, Papps N

“…We explored how an original bedside cardiac assessment (BCA) curriculum that supported professional attitudes, knowledge, and skills scaffolded clinical learning in a cohort of internal medicine clerkship students.Methods: The curriculum urged students to hear patients’ perspectives with humility and as key to diagnostic reasoning. …”
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Seroprevalence and Risk Factors for Toxoplasma gondii Infection in People Living with HIV: A Cross-Sectional Study from Maputo Central Hospital, Mozambique by Manuel L, Comia IR, Miambo RD, Sousa IM, Cuboia N, Carimo A, Massuanganhe SJ, Buene TP, Banze LR, Paraque BP, Nhancupe N, Schooley RT, Santos-Gomes GM, Noormahomed EV, Benson CA

“…Additionally, it aimed to assess the prevalence of neurological and psychiatric disorders (NPD) among study participants and its possible association with toxoplasmosis seropositivity.Methods: We conducted a descriptive, cross-sectional study of 200 patients aged > 18 years who were admitted to Maputo Central Hospital, Maputo, Mozambique, between March 2020 and October 2021. …”
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Risk of exacerbations, hospitalisation, and mortality in adults with physician-diagnosed chronic obstructive pulmonary disease with normal spirometry and adults with preserved rati... by Oskar Wallström, Caroline Stridsman, Helena Backman, Sigrid Vikjord, Anne Lindberg, Fredrik Nyberg, Lowie E.G.W. Vanfleteren

“…We aimed to identify and characterize patients with dnsCOPD, PRISm and spirometrically confirmed COPD (sCOPD) from dCOPD patients in SNAR, stratify them further according to symptoms and exacerbations risk using the Global Initiative for Chronic Obstructive Lung Disease (GOLD) A/B/E classification, and assess differences in risk for exacerbations, cause-specific hospitalisations and mortality. Methods: We enrolled patients aged ≥30 years with dCOPD in the SNAR from 1 January 2014 to 30 June 2022 with complete spirometry i.e., postbronchodilator values for both forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) (index date). …”
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Monitoring the Ecological Security of Esfahan with an Ecosystem Service Approach by Mostafa Keshtkar, Romina Sayahnia

“…The per capita ecological deficit in the city of Esfahan is equal to -3.5. In addition, the rate of resource using raises the potential concerns at this level. …”
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Ordovician conodonts of the Katkoyeh formation in the Kuh-e-Bonorg section, Kalmard Horst (west of Tabas) by Mohammad Nezhadabbas, Abbas Ghaderi, Hadi Jahangir, Ali Reza Ashouri

“…In the current research we have looked for the succession Katkoyeh formation in a section at the south of Kuh-e-Bonorg, eastern flank of the Kalmard anticline, from the age dating view, based on the conodont contents.   Material & Methods In the Kuh-e-Bonorg section, 80 rock samples were collected bed by bed for conodont content while only seven of them were productive. …”
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Interprofessional education in geriatric medicine: towards best practice. A controlled before–after study of medical and nursing students by Sanja Thompson, Kiloran Metcalfe, Katy Boncey, Clair Merriman, Lorna Catherine Flynn, Gaggandeep Singh Alg, Harriet Bothwell, Carol Forde-Johnston, Elizabeth Puffett, Caroline Hardy, Liz Wright, James Beale

“…The optimal learner group size was determined. The equal numbers of participants from each profession for successful IPE are not necessary. …”
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Treatment effects of human amnion-derived mesenchymal stem cells for skin lesions and metastatic pulmonary calcification in calciphylaxis patients – case series and literature revi... by Shijiu Lu, Ming Zeng, Fan Li, Chun Ouyang, Jingjing Wu, Jiaying Hu, Yanggang Yuan, Hongqing Cui, Yi Xu, Wei Liu, Ling Zhang, Yan Lu, Zhonglan Su, Xiaoxue Ye, Cui Li, Anning Bian, Chunyan Jiang, Yugui Cui, Xiang Ma, Song Ning, Xiaolin Lv, Ling Wang, Jiahui Yang, Xiuqin Wang, Ningxia Liang, Changying Xing, Jiayin Liu, Lianju Qin, Ningning Wang

“…Background Calciphylaxis, also termed calcific uremic arteriolopathy (CUA) in patients with end-stage kidney disease (ESKD), is a rare and fatal condition characterized by cutaneous ischemic necrosis.Methods Three patients with calciphylaxis and metastatic pulmonary calcification (MPC) were treated with human amnion-derived mesenchymal stem cells (hAMSCs). …”
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Efficacy, safety and cost-effectiveness of methotrexate, adalimumab or their combination in non-infectious non-anterior uveitis: a protocol for a multicentre, randomised, parallel... by José Antonio Pinto, Alex Fonollosa, Ester Carreño, Maria Isabel Rodriguez, David Diaz-Valle, Diana Peiteado, Luis Rodriguez-Rodriguez, Miguel Cordero-Coma, Marta Tejera Santana, Lidia Cocho, Ana Belen Rivas, Amanda Lopez-Picado, Valentina Calamia, Felix M Francisco Hernandez, Angel Garcia-Aparicio, Javier Garcia-Gonzalez, Jose Juan Mondejar, Leticia Lojo-Oliveira, Llucí Martínez-Costa, Santiago Munoz, Beatriz Rodriguez-Lozano, Esperanza Pato, Elena Molina, Luis Alberto Tebar, Mara Albert Fort, Mayte Ariño Gutierrez, Pedro Arriola Villalobos, Joseba Artaraz Beobide, Antonio Atanes Sandoval, Jose Manuel Sanchez, Francisco Blázquez, Pablo Borges Deniz, Lara Borrego Sanz, Gabriela Bustamante Sanchez-Arnedo, Bruno Casco Silva, Ricardo Cuiña Sardiña, Almudena De Pablo Cabrera, Maria Del Mar Esteban Ortega, Patricia Fernandez Puente, Dalifer Dayanira Nuñez, Javier Garcia Bella, Sara Garcia Carazo, Luis Garcia Onrubia, Jose Maria Morales, Jose Antonio Fernandez, Vanesa Hernandez Hernandez, Inés Hernanz Rodriguez, Jose Maria Cantalapiedra, Ventura Hidalgo Barrero, Maria De Jovani Casano, Sara López Sierra, Virginia Lozano Lopez, Alfredo Madrid Garcia, Rosalia Mendez Fernandez, Pilar Nozal Aranda, Eugenio Perez Blazquez, Chamaida Plasencia Rodriguez, Sheila Recuero Diaz, Ignacio Robles Barrena, Esther Rodriguez Almaraz, Fayna Maria Gonzalez, Guadalupe Rodriguez Martinez, Fredeswinda Isabel Bueno, Ioana Ruiz Arruza, Beatriz Sanchez Marugan, Olga Sanchez Pernaute, Armelle Schlinker Giraud, Alvaro Seijas Lopez, Patricia Simon Alonso, Elia Valls Pascual

“…However, a direct comparison between these two treatment strategies has not been carried out yet.Methods and analysis The Combination THerapy with mEthotrexate and adalImumAb for uveitis (CoTHEIA) study is a phase III, multicentre, prospective, randomised, single-blinded with masked outcome assessment, parallel three arms with 1:1:1 allocation, active-controlled, superiority study design, comparing the efficacy, safety and cost-effectiveness of methotrexate, adalimumab or their combination in non-infectious non-anterior uveitis. …”
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Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic variant by Qinghong Lin, Qinghong Lin, Qinghong Lin, Qinghong Lin, Qinghong Lin, Qinghong Lin, Xuejun Wang, Xuejun Wang, Xuejun Wang, Xuejun Wang, Xuejun Wang, Xiaoliao Peng, Xiaoliao Peng, Xiaoliao Peng, Xiaoliao Peng, Xiaoliao Peng, Xiaosong Han, Xiaosong Han, Xiaosong Han, Xiaosong Han, Xiaosong Han, Xiaoyu Zhang, Xiaoyu Zhang, Xiaoyu Zhang, Xiaoyu Zhang, Xiaoyu Zhang, Ling Sun, Ling Sun, Ling Sun, Ling Sun, Ling Sun, Yan Wang, Shengtao Liu, Shengtao Liu, Shengtao Liu, Shengtao Liu, Shengtao Liu, Xingtao Zhou, Xingtao Zhou, Xingtao Zhou, Xingtao Zhou, Xingtao Zhou

“…BackgroundThis study reports a three-generation Chinese family with polymorphous corneal dystrophy subtype 3 (PPCD3) and keratoconus (KC) aggravation induced by corneal refractive surgery, specifically small incision lenticule extraction (SMILE), in the context of genetic variations.MethodsThe history of illnesses and blood samples of all family members were collected. …”
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