The duration of remission and minimal disease activity after initiation and discontinuation of biological agents in patients with early psoriatic arthritis (data from the all-russi... by E. Yu. Loginova, T. V. Korotaeva, S. I. Glukhova, E. L. Nasonov

“…Remission duration and minimal disease activity (MDA) during treatment with biological agents (BA) and after their discontinuation in patients with early psoriatic arthritis (PsA) have been insufficiently studied.Objective: to study the timing of the onset and duration of remission and MDA after BA initiation and discontinuation in patients with early PsA, followed up according to the Treat-to-Target (T2T) principles.Subjects and methods. The investigation enrolled 34 patients (18 men, 16 women) with early PsA who met the CASPAR criteria, had participated  in the All-Russian Registry and followed up according to the T2T principles.The patients' mean age was 38±11 years; the duration of PsA and psoriasis was 12.0±10.0 and 89.8±91.1 months, respectively. …”
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The Demodex Expert Panel on Treatment and Eyelid Health (DEPTH) Consensus Regarding the Preferred Treatment for Demodex Blepharitis by Donnenfeld E, Nichols KK, Ayres BD, Farid M, Gupta PK, Lindstrom RL, Pflugfelder S, Starr CE, Venkateswaran N, Gaddie IB, Karpecki PM, Koetting C, McGee S, Periman LM, Yeu E

“…Eric Donnenfeld,1 Kelly K Nichols,2 Brandon D Ayres,3 Marjan Farid,4 Preeya K Gupta,5,6 Richard Lyndon Lindstrom,7 Stephen Pflugfelder,8 Christopher E Starr,9 Nandini Venkateswaran,10 Ian Benjamin Gaddie,11 Paul M Karpecki,12 Cecelia Koetting,13 Selina McGee,14 Laura M Periman,15 Elizabeth Yeu16 1Ophthalmic Consultants of Long Island, Long Island, NY, USA; 2School of Optometry, University of Alabama at Birmingham, Birmingham, AL, USA; 3Wills Eye Hospital, Philadelphia, PA, USA; 4Gavin Herbert Eye Institute, UC-Irvine, Irvine, CA, USA; 5Triangle Eye Consultants, Raleigh, NC, USA; 6Department of Ophthalmology, Tulane University, New Orleans, LA, USA; 7Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA; 8Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA; 9Department of Ophthalmology, Weill Cornell Medicine, New York, NY, USA; 10Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA; 11Gaddie Eye Centers, Louisville, KY, USA; 12Kentucky Eye Institute, Lexington, KY, USA; 13Department of Ophthalmology, University of Colorado Medical School, Aurora, CO, USA; 14BeSpoke Vision, Edmond, OK, USA; 15Periman Eye Institute, Seattle, WA, USA; 16Virginia Eye Consultants, Norfolk, VA, USACorrespondence: Elizabeth Yeu, Cornea, Cataract, External Disease and Refractive Surgery, Virginia Eye Consultants/EyeCare Partners, 241 Corporate Blvd, Norfolk, VA, 23502, USA, Tel +1 757 622 2200, Fax +1 757 622 4866, Email eyeulin@gmail.comPurpose: To reach consensus on Demodex blepharitis (DB) treatment approaches using a modified Delphi process involving 15 ocular surface disease experts.Methods: The Demodex Expert Panel on Treatment and Eyelid Health (DEPTH) consisted of 15 well-published ocular surface disease experts. …”
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Efficacy and safety of moxibustion treatment for upper extremity pain disorder and motor impairment in patients with stage I post-stroke shoulder-hand syndrome: a systematic review... by Xiaonan Meng, Xiaonan Meng, Jie Sun, Xintong Su, David Jung Seto, David Jung Seto, Liping Wang, Ying Li, Haikuo Yu, Baixiao Zhao, Jiping Zhao

“…This study aims to evaluate the efficacy and safety of moxibustion treatment for UE-PDMI.MethodsEight databases, including the Cochrane Library, Embase, PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), SinoMed database, China Science and Technology Journal Database (VIP) and WanFang database, were systematically searched, from their inception through May 15 2024, to identify potentially relevant randomized controlled trials (RCTs) on moxibustion for UE-PDMI in SHS patients. …”
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Factors Affecting Vancomycin Trough Concentration; a Population Pharmacokinetic Model in Non-Critical Care Saudi Patients by Alqurain AA, Alrashidi LN, Aloraifej SK, Alkhalifah M, Alsayed HA, Abohelaika S, Alshabeeb MA, Aldhafeeri AS, Almuslim M, Bumozah TN, Alomar MJ, Alshehab AA, Alamer AA, Al-Matouq J, Bidasee KR, Alomar FA

“…This study aims to establish a population-pharmacokinetic (Pop-PK) model for vancomycin in patients admitted to medical wards, with the focus on identification of patient characteristics influencing vancomycin trough concentrations.Methods: A multicenter retrospective study was conducted involving patients aged ≥ 40 years admitted to medical wards in the Eastern Province, Saudi Arabia and initiated on vancomycin, between January to December 2022. …”
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Economic burden of breast cancer in India, 2000–2021 and forecast to 2030 by Rakesh N Pillai, Aleena Alex, Narassima M.S., Vivek Verma, Ajil Shaji, Keechilat Pavithran, D. K. Vijaykumar, Denny John

“…This study introduces a novel approach to forecasting the number of breast cancer cases (based on prevalence rates) and estimating the associated economic impact in India using the autoregressive integrated moving average (ARIMA) model. Methods Data on the prevalence of breast cancer in India from 2000 to 2021 were obtained from the Global Burden of Disease (GBD) database. …”
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Dynamic Muscle Stimulation of the Periorbital Area for Improvement of Blinking in Dry Eye Patients by Chelnis JG, Chelnis A

“…James G Chelnis,1,2 Alexandra Chelnis1 1Manhattan Face and Eye, New York, NY, USA; 2New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USACorrespondence: James G Chelnis, Manhattan Face and Eye, 150 W 58th St #1C, New York, NY, 10019, USA, Tel +1212-484-9707, Email info@manhattanfaceandeye.comPurpose: To investigate whether Dynamic Muscle Stimulation technology (DMSt) in the peri-orbital area improves blinking quality in subjects with lower lid laxity and dry eye disease (DED) due to Meibomian Gland Dysfunction (MGD).Patients and Methods: Eligible subjects had lower lid laxity and DED due to MGD. …”
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Videomängude disain noortele täiskasvanutele. Psühholoogilise heaolu edendamine koosloome kaudu / Participatory Video Game Design for Young Adults: Enhancing Psychological Well-bei... by Taavi Varm

“…While traditional interventions remain essential, creative and participatory methods are gaining recognition for their potential to enhance psychological well-being. …”
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Effects of repeated low-level red light therapy on myopia progression in children: a systematic review and meta-analysis by Haobo Fan, Haobo Fan, Jia Yu, Jia Yu, Aiming Jiang, Aiming Jiang, Qiumei Wei, Xuemin Zhang, Airui Xie, Airui Xie, Junguo Duan, Junguo Duan, Junguo Duan, Junguo Duan

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Six-Month Outcomes from a Prospective, Randomized Study of iStent infinite Versus Hydrus in Open-Angle Glaucoma: The INTEGRITY Study by Iqbal Ike K. Ahmed, John P. Berdahl, Arkadiy Yadgarov, George R. Reiss, Steven R. Sarkisian, Sébastien Gagné, Marco Robles, Lilit A. Voskanyan, Omar Sadruddin, Dari Parizadeh, Jane Ellen Giamporcaro, Angela C. Kothe, L. Jay Katz, Tomas Navratil

“…An interim analysis was performed at month 6. Methods Eyes with OAG, mean IOP ≤ 24 mmHg on zero to three intraocular pressure (IOP)-lowering medications at screening, and with baseline mean diurnal IOP (MDIOP) 21–36 mmHg after medication washout were randomized to standalone implantation of the current generation of three trabecular micro-bypass stents (iStent infinite) or one trabecular bypass stent (Hydrus). …”
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Differentiation of Early Sacroiliitis Using Machine-Learning- Supported Texture Analysis by Qingqing Zhu, Qi Wang, Xi Hu, Xin Dang, Xiaojing Yu, Liye Chen, Hongjie Hu

“…<b>Methods:</b> A total of 92 participants were retrospectively included at our university hospital institution, comprising 30 controls and 62 patients with axSpA, including 32 with nr-axSpA and 30 with r-axSpA, who underwent MR examination of the sacroiliac joints. …”
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A randomized controlled study on the effect of intermittent theta burst stimulation on craving, mood, and cognitive function in alcohol-dependent patients during the withdrawal per... by WANG Haihong, YUAN Chenxin, GAN Hong, JIANG Haifeng, ZHAO Yan, DU Jiang, ZHANG Yi

“…Objective·To explore the effect of intermittent theta burst stimulation (iTBS) targeting the left dorsolateral prefrontal cortex (DLPFC) on reducing craving in alcohol-dependent patients during the withdrawal period, as well as its impact on patients' emotions and cognitive functions.Methods·A total of 41 inpatients with alcohol dependence in the withdrawal period were recruited from the Addiction Department of Mental Health Center, Shanghai Jiao Tong University School of Medicine, and randomly assigned to the experimental group (20 patients) and the control group (21 patients). …”
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E2F2(E2F transcription factor 2) as a potential therapeutic target in meibomian gland carcinoma: evidence from functional and epigenetic studies by Wei Wang, Hetong Wang, Xun Liu, Fei Xu, Qin Tang, Chuanli Zhang, Jiaqi Lin, Limin Zhu, Tingting Lin

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INTERNATIONAL FORUM “OLD AND NEW MEDIA: ALONG THE PATH TOWARDS A NEW AESTHETICS” / МЕЖДУНАРОДНЫЙ ФОРУМ «СТАРЫЕ И НОВЫЕ МЕДИА: ПУТИ К НОВОЙ ЭСТЕТИКЕ»... by BOGATYRYOVA ELENA A.

“…The conference demonstrated the need for new methods of research which would be relevant for new media, the need for development of new aesthetic approaches, the expansion of the categorical apparatus of aesthetics capable of spanning the new media reality and phenomena of digital art. …”
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Efficacy of Combined High-Intensity Laser Therapy and Collagenase Chemonucleolysis in Lumbar Disc Herniation Management: a Prospective Randomized Controlled Trial by Peng Song, Chao Ma, Chenchen Xu, Yongjun Zhang, Yan Yuan

“…This study aimed to investigate whether combining HILT with collagenase chemonucleolysis could accelerate early postoperative recovery in patients with lumbar disc herniation. Methods This single-blind randomized controlled trial was conducted at the Department of Pain Management, The First People’s Hospital of Changzhou, between October 2023 and October 2024. …”
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A Novel Hypoxia-Related Gene Signature with Strong Predicting Ability in Non-Small-Cell Lung Cancer Identified by Comprehensive Profiling by Huajun Yang, Zhongan Wang, Ling Gong, Guichuan Huang, Daigang Chen, Xiaoping Li, Fei Du, Jiang Lin, Xueyi Yang

“…This study is aimed at identifying whether circRNAs could be used as the diagnostic biomarkers for NSCLC. Methods. The heterogeneity of samples in this study was assessed by principal component analysis (PCA). …”
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Application of collateral-dredging tendon-strengthening exercise in postoperative rehabilitation of patients undergoing spinal surgery (通络强筋护脊操在脊柱手术患者术后康复中的应用效果观察)... by ZHU Fengxiang (朱凤祥), HUANG Xiaoling (黄小玲), ZHU Hongying (朱洪英)

“…Objective To investigate the effect of collateral-dredging tendon-strengthening exercise on postoperative rehabilitation of patients undergoing spinal surgery. Methods A convenience sample of 140 patients undergoing spinal surgery under general anesthesia were included as research objects. …”
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Global, regional, and national liver cancer attributable to smoking and alcohol use burden, 1990–2021: analysis for the global burden of disease 2021 study by Chenyi Liu, Taiting Shi, Shu Li, Shiwen Wu, Jiawen Chen, Chao Cai, Mingqin Lu

“…Smoking and alcohol consumption are major risk factors for liver cancer. Methods We analyzed data from the Global Burden of Disease (GBD) Study 2021. …”
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Artificial intelligence in Anatomy: Potential uses and challenges by Lubna Faisal

“…For this new innovative technologies and teaching methods should be incorporated for both learning and assessment of anatomy [2]. …”
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Clinical efficacy and quality of life in elderly patients with lumbar degenerative disease treated with TLIF combined with unilateral pedicle screw fixation: a randomized controlle... by Cheng-Peng Li, Kai-Kai Feng, Xiao-Bing Xiang, Kai-Yin Gao, Wei-Wei Zhang, Zhen-Yu Nie, Dong Zhao, Wen-Xin Liao, Guang-Ru Cao

“…Abstract Objective To conduct a comparative analysis of the clinical efficacy and quality of life in elderly patients with lumbar degenerative disease (LDD) treated with TLIF (transforaminal lumbar interbody fusion) combined with either unilateral pedicle screw fixation (UPSF) or bilateral pedicle screw fixation (BPSF). Methods A total of 112 patients with single- or double-segment lumbar degenerative disease were divided into two groups. …”
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Levels of Neurospecific Peptides, Neurotransmitters and Neuroreceptor Markers in the Serum of Children with Various Sensory Disorders, Mild Cognitive Impairments and Other Neuropat... by George A. Karkashadze, Leyla S. Namazova-Baranova, Leonid M. Yatsik, Olga B. Gordeeva, Elena A. Vishneva, Kamilla E. Efendieva, Elena V. Kaytukova, Natella V. Sukhanova, Natalia S. Sergienko, Julia V. Nesterova, Svetlana E. Kondratova, Madina T. Fatakhova, Alexandr V. Pashkov, Irina V. Naumova, Irina V. Zelenkova, Viktor A. Gankovskiy, Svetlana G. Gubanova, Elizaveta V. Leonova, Alina R. Pankova, Anna A. Alexeeva, Daria A. Bushueva, Tinatin Yu. Gogberashvili, Dmitriy S. Kratko, Safarbegim H. Sadilloeva, Natalia E. Sergeeva, Marina A. Kurakina, Tatiana A. Konstantinidi, Inessa A. Povalyaeva, Margarita A. Soloshenko, Mariya I. Slipka, Viktor V. Altunin, Anastasiya I. Rykunova, Tatiana A. Salimgareeva, Pavel A. Prudnikov, Nadezhda A. Ulkina, Alexey I. Firumyantc, Nikita S. Shilko, Julia E. Kazanceva

“…The aim of the study is to study patterns of neurospecific peptides, neurotransmitters and neuroreceptor markers distribution in the serum of children with various pathogenetic variants of chronic neuropathology. Methods. The study included children from 3 to 16 years old with different pathologies. …”
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