Meta-analysis of the synergistic effect of traditional Chinese medicine compounds combined with conventional Western medicine in the treatment of osteoporosis by Huan Jin, Huan Jin, Cai Huang, Yan Zhang, Ying Dong, Qi Xiong, Di Wang, Di Wang, Ziyi He, Ziyi He, Lin Shen, Chen Ma, Zixian Wang, Lingfeng Zeng, Bo Shuai

“…This study systematically evaluated the synergistic effect of traditional Chinese medicine (TCM) compounds combined with conventional Western medicine (such as bisphosphonates and calcium) compared to Western medicine alone in the treatment of OP through a meta-analysis.MethodsBased on Preferred Reporting Items for Systematic Reviews and Meta-Analyses and the Measurement Tool for Systematic Review Assessment guidelines, databases such as PubMed and Embase were systematically searched (as of March 2025), and 13 randomized controlled trials (RCTs), involving a total of 2,403 patients, were included.ResultsThe integrated Chinese and Western medicine group showed significantly higher lumbar and femoral neck Bone mineral density (BMD) growth rates than the control group, alongside reduced pain visual analogue scale (VAS) scores. …”
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Impact of Teleworking on Work‐Related and Home‐Related Stress at During the First Global Lockdown–The International COVISTRESS Study by Sébastien Couarraze, Guillaume Decormeille, Louis Delamarre, Fouad Marhar, Karen Gbaglo, Raimundo Avilès Dorlhiac, Mickael Berthon, Andy Su‐I Liu, Samuel Antunes, Bruno Pereira, Julien S Baker, Morteza Charkhabi, Ukadike C Ugbolue, Reza Bagheri, José J. Gil‐Cosano, Marek Zak, The COVISTRESS Network, Maëlys Clinchamps, Frédéric Dutheil

“…Objectives Our aim was to measure the impact of teleworking on work‐related and home‐related during the COVID‐19 pandemic. Methods The international study was conducted using an online questionnaire to collect demographic and stress‐related data from individuals worldwide during the 2020 pandemic year. …”
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How could 20-minute neighbourhoods impact health and health inequalities? A policy scoping review by Roxana Pollack, Jonathan R Olsen, Alison Heppenstall, Andreas Hoehn, Jennifer Boyd, Vicki Ponce Hardy, Jennifer Littlejohn, Amy Stevenson, Richard Mitchell, Petra Meier, Jonathan Stokes

“…This scoping review aimed to identify proposed and evidenced pathways to health (inequality) outcomes from international policy plans. Methods We first identified relevant academic literature, searching Scopus, (Ovid) Medline and Embase databases. …”
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Evaluation of the therapeutic effect of repeated photodynamic therapy-assisted SRP treatments on class II furcation by Yikuan Wu, Haoyu Li, Yixiang Wang, Beiying Zhang, Chunsheng Bi, Xiaojun Li

“…Objective: This study aims to evaluate whether repeated photodynamic therapy (PDT) ad-junctive to periodontal scaling and root planing (SRP) provides additional short-term clinical benefits for teeth with class II furcation involvement (FI). Materials and methods: This single-center randomized controlled trial enrolled 27 patients (85 Class II FI sites), randomly allocated to receive either scaling and root planing (SRP) with adjunctive photodynamic therapy (PDT) at baseline, 1, and 2 weeks (Group A) or SRP alone (Group B). …”
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Comparison of two portable metabolic systems for measuring energy expenditure at rest and during exercise in untrained women by Feng Gao, Feng Gao, Feng Gao, Yujing Chan-Yu, Yujing Chan-Yu, Zhi Li, Zhi Li, Yongfu Liu, Yongfu Liu, Fei Liu, Fei Liu, Di Liu, Wenjun Yu, Wenjun Yu, Weiwei Chen, Junhua Wang, Junhua Wang, Junhua Wang, Shenglong Le, Shenglong Le, Shenglong Le

“…This study aimed to compare EE measurements obtained using the COSMED K5 (K5) and CORTEX METAMAX 3B (M3B) during the resting state and submaximal-intensity exercise in women without self-reported regular exercise training.MethodsTwenty women aged 21.4 ± 1.5 years completed two measurements, including resting in a seated position and cycling on a simple upright ergometer at 30 W, 40 W, 50 W, and 60 W. …”
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Agarwood Chromone Alleviates Gastric Ulcers by Inhibiting the NF-κB and Caspase Pathways Based on Network Pharmacology and Molecular Docking by Canhong Wang, Yulan Wu, Bao Gong, Junyu Mou, Xiaoling Cheng, Ling Zhang, Jianhe Wei

“…<b>Objectives:</b> This study aimed to investigate the ameliorative effect of agarwood chromone on gastric ulcers and its mechanism. <b>Methods:</b> Network pharmacology was used to predict the disease spectrum and key therapeutic targets of 2-(2-phenylethyl)chromone (CHR1) and 2-(2-(4-methoxyphenyI)ethyl)chromone (CHR2). …”
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The oncolytic avian reovirus p17 protein suppresses invadopodia formation via disruption of TKs5 complexes and oncogenic signaling pathways by Chao-Yu Hsu, Jyun-Yi Li, Jyun-Yi Li, Wei-Ru Huang, Wei-Ru Huang, Tsai-Ling Liao, Tsai-Ling Liao, Hsiao-Wei Wen, Chi-Young Wang, Chi-Young Wang, Lon-Fye Lye, Brent L. Nielsen, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu

“…Cancer cell migration and invadopodia formation are essential processes in metastasis, and targeting these mechanisms could be beneficial in limiting cancer progression.MethodsThis study investigated the effects of ARV p17 protein on cancer cell migration and invadopodia formation in HeLa and A549 cell lines. …”
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Effects of miR-204-3p inhibitor on epithelial-mesenchymal transition and silicosis fibrosis in silicon dioxide-induced alveolar epithelial cells by Fang CHEN, Jing YU, Wenxuan HU, Yangyang PI, Xi ZHANG, Luning WANG, Ping ZHAO, Faxuan WANG

“…ObjectiveTo investigate the effect of miR-204-3p inhibitor on the epithelial-mesenchymal transition (EMT) process and silicosis fibrosis in silicon dioxide dust-induced alveolar epithelial cells. MethodsA co-culture model of macrophages and epithelial cells was established using a Transwell chamber. …”
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Research Influence оf Nitrogen оn Formation Condensate Loss During the Development оf the Chayandinskoye Field by R. K. Dobrolyubova, E. I. Inyakina, I. I. Krasnov

“…The analysis of the performed studies confirmed that nitrogen affects the solubility of the condensate in gases to varying degrees and that the methane-type condensates of the Chayandinskoye field have better solubility, all other things being equal.Materials and methods of research. The works [2-9] consider laboratory studies and analytical calculations of the fluid-dynamic properties of gas condensate mixtures in the presence of nitrogen in the system, as well as other non-hydrocarbon components that affect the loss of hydrocarbons in the deposit. …”
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Measuring what matters: Building impact pathways to actionable information for the weADAPT platform by S. Bharwani, K. Williamson, R. Butterfield

“…This study addresses this gap by assessing the usability and impact of the weADAPT online platform through a mixed-methods approach, combining a user survey and semi-structured interviews. …”
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Post-registration experience of nivolumab in advanced hepatocellular carcinoma: an international study by Dominik Bettinger, Bo Yu, David Szafron, Yinghong Wang, Mahvish Muzaffar, Thomas Marron, Uqba Khan, Yi-Hsiang Huang, David J Pinato, Ahmed Kaseb, Anwaar Saeed, Tomi Jun, Sirish Dharmapuri, Musharraf Navaid, ChiehJu Lee, Anushi Bulumulle, Sonal Paul, Petros Fessas, Neil Nimkar, Hannah Hildebrand, Tiziana Pressiani, Yehia I Abugabal, Nicola Personeni, Lorenza Rimassa, Celina Ang, Abdul Rafeh Naqash, Francesca Benevento

“…Post-registration data of treatment in a real-world setting is lacking.Patients and methods We performed an international, multicenter observational study to confirm safety and efficacy of nivolumab in 233 patients treated outside clinical trials from eight centers in North America, Europe and Asia.Results Patients received nivolumab for Barcelona Clinic Liver Cancer stage C (n=191, 92.0%) and Child-Pugh (CP) A (n=158, 67.8%) or B (n=75, 32.2%) HCC as first (n=85, 36.5%) or second to fourth systemic therapy line (n=148, 63.5%). …”
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Intravascular lithotripsy vs. rotational atherectomy on coronary microcirculation: a retrospective multicenter propensity-matched multicenter study by Xi Zhang, Xi Zhang, Xi Zhang, Peijian Wang, Chenguang Li, Tao Zhao, Tao Zhao, Tao Zhao, Jiaji He, Jiaji He, Jiaji He, Bin Liu, Qing Jin, Qing Jin, Qing Jin, Pin Gan, Pin Gan, Pin Gan, Jilei Zhang, Jilei Zhang, Jilei Zhang, Qiang Xue, Qiang Xue, Qiang Xue

“…However, the impact of intravascular lithotripsy (IVL) on CMD remains unclear, and no studies have directly compared IVL and rotational atherectomy (RA) in the context of CMD.ObjectiveThis study aimed to evaluate CMD, as indicated by angiographic microvascular resistance (AMR), in patients undergoing IVL- or RA-assisted PCI for heavily calcified coronary lesions.MethodsThis multicenter retrospective cohort study enrolled patients underwent either RA- or IVL-assisted percutaneous coronary intervention (PCI) at three centers. …”
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Association between atherogenic index of plasma and physical dysfunction: a cross-sectional study of middle-aged and older adults in China by Jianghui Zhou, Jianghui Zhou, Jianghui Zhou, Jianghui Zhou, Jianghui Zhou, Yun Chang, Yun Chang, Yun Chang, Yun Chang, Hechen Shen, Hechen Shen, Hechen Shen, Hechen Shen, Hechen Shen, Meng Zhang, Meng Zhang, Meng Zhang, Meng Zhang, Meng Zhang, Yuchao Wang, Yuchao Wang, Yuchao Wang, Yuchao Wang, Yuchao Wang, Xiaoyu Liang, Xiaoyu Liang, Xiaoyu Liang, Xiaoyu Liang, Wenqing Gao, Wenqing Gao, Wenqing Gao, Wenqing Gao, Wenqing Gao

“…This study explored the dose–response relationship between AIP and physical dysfunction.MethodsData from 11,369 CHARLS participants (aged ≥45 years) in 2015 and 2018 were analyzed using univariate and multivariate logistic regression, adjusting for demographics and lifestyle factors. …”
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Predicting diabetic retinopathy stages using a simple nerve conduction measuring device, DPNCheck®: a retrospective observational study by Mayu Sakai, Mayu Sakai, Mayu Sakai, Takehiro Kato, Takehiro Kato, Takuma Ishihara, Ken Takao, Ken Takao, Tokuyuki Hirose, Tokuyuki Hirose, Sodai Kubota, Sodai Kubota, Saki Kubota-Okamoto, Saki Kubota-Okamoto, Toshinori Imaizumi, Toshinori Imaizumi, Yoshihiro Takahashi, Yoshihiro Takahashi, Masami Mizuno, Masami Mizuno, Takuo Hirota, Takuo Hirota, Yukio Horikawa, Yukio Horikawa, Hirokazu Sakaguchi, Hirokazu Sakaguchi, Shin Tsunekawa, Daisuke Yabe, Daisuke Yabe, Daisuke Yabe

“…In contrast, DPNCheck® is a simpler alternative that quantifies neuropathy severity through the severity of the estimated modified Baba classification (eMBC).Materials and methodsUsing electronic medical records (EHRs), we identified individuals with diabetes who underwent DPNCheck® and subsequent ophthalmologic assessment for DR. …”
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Study on the risk factors for colorectal polyp recurrence: a cross-sectional retrospective cohort study by Fang Li, Fang Li, Mengge Lu, Mengge Lu, Bo Xu, Zheng Xiang, Zheng Xiang, Yuan Zhang, Yuan Zhang, Boran Cao, Xuewei Li, Xuewei Li, Yanan Wu, Yanan Wu, Rongrong Zheng, Rongrong Zheng, Qin Cai, Qin Cai, Jun Shen, Pengfei Xin, Pengfei Xin, Lianbo Xiao, Lianbo Xiao, Yanqin Bian, Yanqin Bian

“…ObjectiveTo investigate the factors associated with the recurrence of colorectal polyps.MethodsData on polyp recurrence and related factors, including gender, age, BMI, family history, smoking history, alcohol consumption history, gallbladder disease history, food allergy, polyp size, number, and pathological classification, Helicobacter pylori (Hp) infection, parathyroid hormone, gastrin, and blood lipid levels, were collected as exposure factors. …”
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Exploring the co‐morbid relationship between Alzheimer's disease and lung cancer in the 5xFAD transgenic mouse model by Mingfeng Li, Xinghan Wu, Lin Jiang, Min Liu, Gong Yanju, Xiaomeng Li, Fan Tian, Fan Ye, Jinlong Wang, Siyuan Wang, Chuan Qin, Ling Zhang

“…However, the precise mechanism by which AD antagonizes lung cancer progression warrants further elucidation. Methods To this end, we established a co‐morbidity model using 5xFAD transgenic mice induced with the carcinogen urethane. …”
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Evaluation and comparison of large language models’ responses to questions related optic neuritis by Han-Jie He, Han-Jie He, Fang-Fang Zhao, Jia-Jian Liang, Yun Wang, Qian-Qian He, Qian-Qian He, Hongjie Lin, Jingyun Cen, Feifei Chen, Tai-Ping Li, Zhanchi Hu, Jian-Feng Yang, Lan Chen, Carol Y. Cheung, Yih-Chung Tham, Yih-Chung Tham, Yih-Chung Tham, Ling-Ping Cen, Ling-Ping Cen, Ling-Ping Cen, Ling-Ping Cen

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Prevalence of cardiovascular diseases and risk factor assessment in breast cancer survivors exposed to cardiotoxic therapy by Marina V. Vitsenya, Irina V. Barinova, Nana V. Pogosova, Tatevik A. Terteryan, David T. Kuchiev, Yulia V. Khrushcheva, Anna A. Gerasimova, Anastasiya Y. Filatova, Nursiyat M. Ibragimova, Olga O. Frolkova, Fail T. Ageev

“…Aim: To evaluate the frequency of CVDs and their risk factors, and total CVR in BC patients who have undergone cardiotoxic antitumor treatment to determine the need for the development of cardiac rehabilitation programs in this patient category. Methods: This was a single center cross-sectional study performed in 2021 to 2023 in a specialized cardiology clinic in 90 women who had undergone cardiotoxic breast cancer therapy. …”
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CT-SEGMENTED BONE SUV IN MULTIPLE MYELOMA: A COMPARATIVE STUDY OF ¹⁸F-FDG AND ⁶⁸GA-PSMA PET/CT by Alexandre Mercuri Barbosa, Maria Emília Seren Takahashi, Stephan Pinheiro Macedo Souza, Edna Marina Souza, Sérgio Querino Brunetto, Cármino Antonio de Souza, Irene Gyongyver Heidemarie Lorand-Metze, Celso Darío Ramos

“…Materials and Methods: The study included ¹⁸F-FDG and ⁶⁸Ga-PSMA PET/CT images acquired within a 1- to 8-day interval from 15 patients (53% male, mean age 66.7 ± 10.7 years) with symptomatic, biopsy-proven MM. …”
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Prevalence and associated factors of syphilis among female sex workers in East Africa: a systematic review and meta-analysis by Solomon Gedfie, Woldeteklehymanot Kassahun, Abdu Jemal, Muluken Gashaw, Alembante Bazezew, Marye Nigatie, Getinet Kumie, Tadesse Misganaw, Zewdu Tefera, Bewuketu Belete Alemu, Bahriew Mezgebu, Brhanu Kassanew, Ephrem Tamrat, Wagaw Abebe, Agenagnew Ashagre, Assefa Sisay, Yalewayker Gashaw, Melese Abate Reta, Melese Abate Reta

“…Therefore, this review aimed to estimate the pooled prevalence of syphilis and identify the associated factors among female sex workers in the East African region.MethodsThis systematic review and meta-analysis was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. …”
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