Effectiveness of Pharmacist-Led Training Regarding Medication for Type 2 Diabetes, Based on Patient and Physician Medication-Related Issues Identified in China by Yang ZH, Cheng CJ, Chen GM, Huang J, Zhou H, Jiang J, Ye Z, Weng YF, Tan HH

“…Zhong Hui Yang,1,* Chang Juan Cheng,1 Guo Mei Chen,1 Ji Huang,1,* Hai Zhou,2 Jie Jiang,3 Zhen Ye,4 Yu Fang Weng,5 Hai Hong Tan1 1Department of Pharmacy, Taicang First People’s Hospital, Soochow University, Taicang, Jiangsu, People’s Republic of China; 2Health Service Center of Chengxiang Town, Taicang, Jiangsu, People’s Republic of China; 3Taicang Port District People’s Hospital, Taicang, Jiangsu, People’s Republic of China; 4Huangjing People’s Hospital of Taicang City, Taicang, Jiangsu, People’s Republic of China; 5Taicang Shuangfeng People’s Hospital, Taicang, Jiangsu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chang Juan Cheng, Department of Pharmacy, Taicang First People’s Hospital, Soochow University, No. 58, Changsheng South Road, Taicang City, Jiangsu Province, People’s Republic of China, Tel +86 13915495574, Email 532782210@qq.com Guo Mei Chen, Department of Pharmacy, Taicang First People’s Hospital, Soochow University, No. 58, Changsheng South Road, Taicang City, Jiangsu Province, People’s Republic of China, Tel +86 13776297087, Email 23451210@qq.comAim: To determine the effect of pharmacist-led specialized medication training on rational drug prescription by family physicians, and to characterize the drug-related issues and glycemic control of patients.Methods: We performed a study led by clinical pharmacists. …”
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Incidence and Risk Factors of Tuberculosis-Associated Chronic Obstructive Pulmonary Disease by Joo DH, Kim MC, Sin S, Kang HR, Song JH, Kim HJ, Song MJ, Kwon BS, Kim YW, Lee YJ, Park JS, Lee JH, Lee YJ

“…We evaluated the incidence of tuberculosis-associated COPD and compare the characteristics of patients with and without COPD.Patients and Methods: This multicenter, retrospective cohort study included 351 patients treated with anti-tuberculosis drugs for more than 6 months in four hospitals in Korea, followed for 11 years (132 months). …”
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A Prospective, Crossover, Randomized, Double-Blind Clinical Study Comparing the Effectiveness and Ocular Comfort of 0.1% Hyaluronic Acid and 0.3% Hyaluronic Acid in Patients With D... by Kim SJ, Yoo WS, Kwon LH, Kim RB, Yoon HJ, Yoon KC

“…Korea) to treat dry eye disease (DED).Methods: This study was designed as a prospective, crossover, randomized, and double-blind study. …”
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Effectiveness and Safety of Tildrakizumab in Elderly and Frail Elderly Psoriatic Patients Up to 2 years by Mastorino L, Dapavo P, Burlando M, Gisondi P, Maronese CA, Ruggiero A, Galluzzo M, Pisani MC, Sacchelli L, Caldarola G, Avallone G, Marzano AV, Megna M, Campione E, Loconsole F, Bardazzi F, De Simone C, Quaglino P, Ribero S

“…To date, there is no study in the literature examining possible differences between frail and non-frail elderly with psoriasis being treated with tildrakizumab.Patients and Methods: The present multicentre retrospective study evaluated the effectiveness, drug survival and safety up to 2 years of treatment with tildrakizumab in the elderly (≥ 65 years) comparing frail and non-frail patients. …”
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Analysis of Factors Affecting Quality of Life (QoL) in Middle-Aged Stroke Patients (Under 65 Years Old) in the Rehabilitation Phase: Multivariate Regression Analysis by Lumbantobing VBM, Priastomo M, Kosasih CE, Rhamelani P, Anggadiredja K, Adnyana IK

“…Valentina Belinda M Lumbantobing,1,2,* Mukti Priastomo,1 Cecep Eli Kosasih,3 Putri Rhamelani,4 Kusnandar Anggadiredja,1 I Ketut Adnyana1,* 1Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, Institut Teknologi Bandung, Bandung, West Java, Indonesia; 2Department of Fundamental Nursing, Faculty of Nursing, Universitas Padjadjaran, Bandung, West Java, Indonesia; 3Department of Critical Nursing, Faculty of Nursing, Universitas Padjadjaran, Bandung, West Java, Indonesia; 4Faculty of Nursing, Universitas Padjadjaran, Sumedang, West Java, Indonesia*These authors contributed equally to this workCorrespondence: Valentina Belinda M Lumbantobing, Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, Institut Teknologi Bandung, Bandung, West Java, Indonesia, Email valentina@unpad.ac.id I Ketut Adnyana, Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, Institut Teknologi Bandung, Bandung, West Java, Indonesia, Email ketut@itb.ac.idPurpose: This study analyzed factors influencing the quality of life (QoL) in stroke patients during the rehabilitation phase so that rehabilitation professionals, caregivers, and stroke patients can pay attention to all aspects that contribute significantly to a better QoL and can design appropriate interventions to improve patient welfare and support a more significant recovery process.Patients and Methods: A non-experimental quantitative approach with a cross-sectional design was conducted with 76 adult stroke patients in the rehabilitation phase. …”
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Targeted Delivery of Exosome-Derived miRNA-185-5p Inhibitor via Liposomes Alleviates Apoptosis and Cuproptosis in Dilated Cardiomyopathy by Xu S, Zeng Y, Tan X, Zhang G, Xu A, Fan H, Yu F, Qin Z, Song Y, Jiang Y, Wang X, Zhang D, Nong Y, Lian D, Tang J, Zhou Y

“…This study explores a novel treatment strategy involving the delivery of exosome-derived miRNA-185-5p inhibitors encapsulated in liposomes, aiming to target cardiac tissue and alleviate myocardial apoptosis and cuproptosis in DCM.Methods: The miRNA-185-5p inhibitor, identified in our previous study and extracted from exosomes, was encapsulated in liposomes functionalized with a cardiac-targeting peptide. …”
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Silencing NEDD4L Effectively Inhibits the Malignant Behaviors of Hepatocellular Carcinoma by Dai J, Zhu T, Wan J, Liu R, Song Y, Zhang D, Wang X, Zhang H, Li W, Lin J, Zhu X, Liu Y

“…However, research focusing on its involvement in hepatocellular carcinoma (HCC) remains relatively scarce.Methods: This investigation examined NEDD4L’s expression, survival implications, and regulatory mechanisms of NEDD4L in HCC using RNA-seq and microarray data across multiple databases. …”
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Hs-CRP, Diabetic Status, and Adverse Events Among Patients Receiving Statin Therapy Following PCI—A Prospective Registry-Based Study by Chen X, Wang HY, Sun W, Lin Z, Qiao Z, Bian X, Yin D, Feng L, Zhu C, Song W, Wang H, Jia L, Dong Q, Dou K

“…This study aims to evaluate the impact of T2DM on the relationship between residual inflammatory risk, as assessed by a simple, economical, and easily measurable biomarker—high-sensitivity C-reactive protein (hs-CRP)—and clinical outcomes in statin-treated coronary heart disease (CHD) patients with drug-eluting stent (DES) implantation.Patients and Methods: 8,628 individuals with CHD treated with statins and DES implantation at Fuwai Hospital were included. …”
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Development and Validation of a Diagnostic Model for Stanford Type B Aortic Dissection Based on Proteomic Profiling by Zhao Z, Chen T, Liu Q, Hu J, Ling T, Tong Y, Han Y, Zhu Z, Duan J, Jin Y, Fu D, Wang Y, Pan C, Keyoumu R, Sun L, Li W, Gao X, Shi Y, Dou H, Liu Z

“…This study focused on developing a model to improve the diagnosis in a population.Patients and Methods: Serum biomarkers were investigated in 88 participants using proteomic profiling combined with machine learning. …”
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TACE Combined with Lenvatinib-PD-1 Versus TACE Monotherapy as Conversion Therapy Before Liver Resection in Unresectable Hepatocellular Carcinoma: A Retrospective, Propensity Score... by Lu C, Liu R, Zhang Y, Luo J, Luo C, Jiang Z, Huang M, Qiu C, Chen J

“…Our aim was to compare the clinical benefits of TACE combined with Lenvatinib-PD-1 inhibitor versus TACE monotherapy as conversion therapy for patients with uHCC who subsequently underwent liver resection (LR).Materials and Methods: This retrospective study included 213 uHCC patients who underwent LR after receiving either TACE combined with Lenvatinib plus PD-1 inhibitor (combination group, n=109) or TACE monotherapy (monotherapy group, n=104). …”
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Investigation of Population Changes and Determination of the Bean Pod Borer Helicoverpa armigera (Lepidoptera:Noctuidae) Peak in Bean Phaseolus vulgaris Linnaeus Fields by Pheromon... by Sedighe Ashtari

“…(Lep.Noctuidae), is one of the important pests. Materials and Methods To address the damage caused by this pest to bean crops, a project was conducted to study changes in the population of adult insects and larvae over two years (2022 and 2023). …”
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Co-Production of KPC-2 and NDM-5 in a Carbapenem-Resistant Klebsiella Pneumoniae Clinical Isolate: Genetic Insights and Risks by Xia Y, Zhou P, Gao H, Wu X, Zhou Y, Han W, Wan C, Wu Q, Ding J, Yu F

“…Understanding the genetic drivers of resistance and transmission is critical.Methods:  A multidrug-resistant CRKP strain, KP3T58, co-harboring blaKPC-2 and blaNDM-5, was isolated from an ICU patient. …”
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Effect of Remimazolam versus Propofol on Hemodynamics in Elderly Hypertensive Patients Undergoing Gastroenteroscopy: A Multicenter, Randomized Controlled Clinical Trial by Gu Q, Zeng D, Lin D, Zou J, Sun J, Wang H, Chen S, Zhang H, Xu B, Liu W, Shu J

“…Qian Gu,1,2,* Deling Zeng,3,* Dayong Lin,4,* Jiang Zou,5,* Jiaxin Sun,1 Huaiming Wang,1 Shiwei Chen,2 Hongwei Zhang,1 Bo Xu,1 Wusong Liu,6 Jinjun Shu1 1Department of Anesthesiology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 2Department of Anesthesiology, Xichang People’s Hospital, Xichang, People’s Republic of China; 3Health Management Center, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 4Department of Anesthesiology, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 5Department of Anesthesiology, Sichuan Women’s and Children’s Hospital/Women’s and Children’s Hospital, Chengdu Medical College, Chengdu, People’s Republic of China; 6Department of Endoscopy Center, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jinjun Shu, Department of Anesthesiology, Sichuan Cancer Hospital, No. 55, Section 4, South Renmin Road, Chengdu, 610041, People’s Republic of China, Email shujinjun@scszlyy.org.cn Wusong Liu, Department of Endoscopy Center, Sichuan Cancer Hospital, No. 55, Section 4, South Renmin Road, Chengdu, 610041, People’s Republic of China, Email liuwusong@scszlyy.org.cnPurpose: This study aimed to compare the effects of remimazolam and propofol on hemodynamics in elderly hypertensive patients undergoing gastroenteroscopy.Methods: In this multicenter, single-blind, randomized clinical trial, 220 hypertensive patients (65– 75 years) scheduled for gastroenteroscopy were randomly assigned to receive either remimazolam (group R, n=110; 0.3 mg/kg induction followed by 0.2– 1 mg/kg/h maintenance) or propofol (group P, n=110; 1.5 mg/kg induction followed by 2– 6 mg/kg/h maintenance), both combined with 0.1 μg/kg sufentanil. …”
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Analysis of the Regulatory Effects of lncRNAs on Kidney Tissue in Ascites Susceptible Broiler by Kasra Ahmadian, Mohammadreza Nassiry, Karim Hasanpur, Ali Javadmanesh

“…For this reason, the lncRNAs obtained from the RNA-seq data of the kidney tissue were investigated in the occurrence of ascites.Materials and Methods :700 one-day-old chicks from one of the paternal lines of a commercial strain were kept under standard conditions until 21 days old. …”
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Associations Among Obstructive Sleep Apnea, Thyroid Function and Morphology Changes by Xie Y, Zhang H, Cao Z, Zhou Y, Lu C, Yin L, Zhu S, Su Y, Niu X, Ma L, Yuan Y, Zhang Y, Wang Z, Liu H, Ren X, Shi Y

“…Yushan Xie,1,2,* Hongli Zhang,3,* Zine Cao,1,* Yanuo Zhou,1,2 Chendi Lu,1,2 Libo Yin,4 Simin Zhu,1,2 Yonglong Su,1,2 Xiaoxin Niu,1,2 Lina Ma,1,2 Yuqi Yuan,1,2 Yitong Zhang,1,2 Zitong Wang,1,2 Haiqin Liu,1,2 Xiaoyong Ren,1,2 Yewen Shi1,2 1Department of Otorhinolaryngology—Head and Neck Surgery, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China; 2Shaanxi Provincial Key Laboratory for Precision Diagnosis and Treatment of Otorhinolaryngology, Xi’an, People’s Republic of China; 3Department of Ultrasound, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China; 4Otolaryngology Head and Neck Surgery Department, Xi’an Central Hospital, Xi’an, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiaoyong Ren, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China, Email renxiaoyong@sina.vip.com Yewen Shi, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China, Email shiyewen59@outlook.comPurpose: This study unveils the complex interplay among obstructive sleep apnea (OSA), thyroid function, and morphological changes.Methods: Data from 1,102 patients were collected retrospectively from the Department of Otorhinolaryngology—Head and Neck Surgery of the Second Affiliated Hospital of Xi’an Jiaotong University from 2012 to 2023. …”
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Investigation of Smoking Cessation Status and Its Influencing Factors in Patients with Chronic Obstructive Pulmonary Disease by Fan M, Fang YJ, Chen J, Zhong X, Zhang N, Zeng Z, Xiao D, Qi X, Liang W, Li X, Gao Y, Li S, Su Z

“…This study aimed to investigate the status quo and influencing factors of smoking cessation in patients with SAD or COPD, which is crucial for improving prevention and treatment of chronic airway diseases.Patients and Methods: In this multicenter, prospective cohort investigation, questionnaire survey and one-year follow-up study were conducted in SAD and COPD patients with smoking history. …”
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Antimicrobial efficacy of methylene blue-functionalized graphene oxide-mediated photodynamic therapy against Enterococcus faecalis in root canal disinfection by Rizwan Jouhar, FCPS, Mohamad S. Halim, M.Res.Dent, Sayed A. Quadri, MD, Muhammad A. Ahmed, PhD, Faheem Shah, PhD

“…Abstract: Objective: This study assessed the antimicrobial efficacy of photodynamic therapy (PDT) using functionalized graphene oxide with methylene blue (MB/rGO) to achieve root canal disinfection against Enterococcus faecalis. Methods: In this in vitro study, E. faecalis biofilms were developed on 105 single-rooted teeth after decoronation over 21 days. …”
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Clinical Relevance of Elevated Serum Carcinoembryonic Antigen in Allergic Bronchopulmonary Aspergillosis/Mycosis: A Multicenter Retrospective Study by Ge H, Cai R, Chen X, Liu B, Hu X, Deng S, Li H, Dai L, Tang J, Tang H, Gong X, Wu C, Wang G, Li G, Liu B, Wang J, Tang Y, Li X, Feng J

“…Few studies on ABPA/M cases presenting with elevated serum CEA levels have been reported.Patients and Methods: A cohort of 115 patients diagnosed as ABPA/M were divided into two groups (CEA normal and CEA elevated). …”
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Effect of Wuzhuyu Decoction on alcoholic gastric ulcer and its mechanism by GAO Ruiyang, LI Jingyao, LI Pingxiang, GE Keli

“…Objective To investigate the effect of Wuzhuyu Decoction (WZYD) on alcoholic gastric ulcer and its mechanism. Methods A total of 120 female KM mice, aged 8 weeks, were randomly divided into normal control group (group A), model control group (group B), ranitidine group (group C), and low-, middle-, and high-dose WZYD groups (groups D-F), with 20 mice in each group. …”
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Understanding the Needs and Wishes of Older Adults in Interprofessional Treatment for Malnutrition and Sarcopenia: A Grounded Theory Study by Boxum SD, Van Exter SH, Reinders JJ, Drenth H, Van den Berg MG, Tieland M, Geluk-Bleumink A, Spoorenberg SL, Finnema E, Van der Wees PJ, Koenders N, Jager-Wittenaar H

“…This study aimed to understand the needs and wishes of community-dwelling older adults regarding interprofessional treatment for (risk of) malnutrition and sarcopenia.Methods: We conducted a grounded theory study. Data collection involved semi-structured interviews and focus groups with community-dwelling older adults who are undergoing treatment or have been treated for (risk of) malnutrition and/or sarcopenia. …”
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