Evaluation of the Digital Support Tool Gro Health W8Buddy as Part of Tier 3 Weight Management Service: Observational Study by Petra Hanson, Farah Abdelhameed, Mohammed Sahir, Nick Parsons, Arjun Panesar, Michaela de la Fosse, Charlotte Summers, Amit Kaura, Harpal Randeva, Vinod Menon, Thomas M Barber

“…ObjectiveThis service evaluation study assessed the use, effectiveness, and clinical impact of the W8Buddy digital support tool as part of the National Health Service WMS. MethodsW8Buddy, a personalized digital platform, provides a tailored weight management plan to empower individuals and was collaboratively developed with input from patients, the clinical team, and DDM Health. …”
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The clinical and radiological effectiveness of autologous bone marrow derived osteoblasts (ABMDO) in the management of avascular necrosis of femoral head (ANFH) in sickle cell dise... by Mir Sadat‐Ali, Abdallah S. Al‐Omran, Khalid AlTabash, Sadananda Acharya, Tarek M. Hegazi, Mona I. Al Muhaish

“…We report here our experience with the injection of ABMDO to manage ANFH and report our medium‐term results, the progression of the ANFH if any and the delay in total hip arthroplasty. (THA). Methods Sixty‐Three (63) patients with SCD and ANFH were examined and thoroughly investigated, and those who had ANFH < grade II were consented to receive ABMDO. …”
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Dexmedetomidine-enhanced chest wall fascial plane blocks in ultra-fast-track minimally invasive heart valve surgery: a randomized controlled trial by Shen-Jie Jiang, Tian Jiang, Han-Wei Wei, Xiao-Kan Lou, Yu Wang, Mei-Juan Yan

“…This randomized controlled trial evaluated whether adding 1 μg/kg dexmedetomidine to 0.375% ropivacaine for chest wall fascial plane blocks enhances opioid sparing in ultra-fast-track (UFT) minimally invasive heart valve surgery. Methods Seventy-six elective patients were randomized (1:1) in a double-blind manner. …”
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FACTORS ASSOCIATED WITH ANXIETY AND DEPRESSION SPECTRUM DISORDERS IN BEHCHET’S DISEASE by P. S. Ovcharov, T. A. Lisitsyna, D. Yu. Veltishchev, O. F. Seravina, O. B. Kovalevskaya, S. I. Glukhova, Z. S. Alekberova, E. L. Nasonov

“…Objective: to determine the main factors associated with the development and manifestations of anxiety and depression spectrum disorders (ADSDs) in patients with Behcet’s disease (BD).Subjects and methods. This investigation was conducted within the framework of the interdisciplinary scientific program «Stress factors and mental disorders in rheumatic diseases». …”
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Transvaginal extraction of the specimen after total laparoscopic right hemicolectomy or extended right hemicolectomy for right colon cancer: an analysis of 25 cases by Deng Jianzhong, Zhang Zilang, Lin Yiban, Guo Xiaoxi, Li Zhaoyang, Wang Weichun, Yu Si

“…[Objectives] To determine the clinical effectiveness of transvaginal extraction of the specimen after total laparoscopic right hemicolectomy or extended right hemicolectomy for right colon cancer. [Methods] This was a retrospective analysis of 25 patients with right colon caner treated with transvaginal extraction of the specimen after total laparoscopic right hemicolectomy or extended right hemicolectomy at the First People’s Hospital of Foshan between January 2017 and January 2021. …”
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Balneotherapy for the treatment of post-COVID syndrome: a randomized controlled trial by Diana Ovejero, Anna Ribes, Judit Villar-García, Marta Trenchs-Rodriguez, Daniel Lopez, Xavier Nogués, Robert Güerri-Fernandez, Natalia Garcia-Giralt

“…This randomized controlled trial aims to evaluate the effects of balneotherapy (BT) on PACS symptomatology. Methods Ninety-eight adults with PACS visited at Hospital del Mar Research Institute, Barcelona (Spain) were included to the study. …”
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Adenoviral-vectored neoantigen vaccine augments hyperexpanded CD8+ T cell control of tumor challenge in mice by David Li, Gabriel Dagotto, Alessandro Colarusso, Robert C Patio, Tochi Anioke, Victoria Giffin, Ruoran Guan, Trisha Anand, Esther Mbiwan, Malika Aid, Dan Barouch

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Caracterización clínica, epidemiológica y genealógica de la esquizofrenia en pacientes de la Policlínica Alcides Pino Bermúdez de Holguín by Maydoli Cardet Escalona, Olga Antonia Álvarez Estrabao, Sara Meneses Álvarez

“…Objectives: to describe the clinical behavior: predominant clinical form, age of onset of symptoms, history of attempted suicide, symptoms reported by cases; epidemiology: distribution of cases by age and sex, skin color and school level, and genealogy of disease. Methods: a descriptive cross- sectional study was carried out. …”
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THE FREQUENCY AND SEVERITY OF EXTRASKELETAL MANIFESTATIONS OF ANKYLOSING SPONDYLITIS by A. A. Godzenko, A. G. Bochkova, O. A. Rumyantseva, Yu. O. Korsakova, I. Yu. Razumova, V. V. Badokin, Sh. F. Erdes

“…Objective: to assess the frequency and severity of extraskeletal manifestations (ESMs) of AS in the authors' own clinical practice. Subjects and methods. 452 patients (363 men and 89 women) with AS fulfilling the 1984 relevant New York criteria were examined at the V.A. …”
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Satisfactory Evaluation of Call Service Using AI After Ureteral Stent Insertion: Randomized Controlled Trial by Ukrae Cho, Yong Nam Gwon, Seung Ryong Chong, Ji Yeon Han, Do Kyung Kim, Seung Whan Doo, Won Jae Yang, Kyeongmin Kim, Sung Ryul Shim, Jaehun Jung, Jae Heon Kim

“…ObjectiveThis study aimed to assess the effectiveness of an AI-based prediction tool in providing patients with information about potential complications from ureteroscopy and ureteric stent placement and indicating the need for early additional therapy. MethodsOverall, 28 patients (aged 20-70 years) who underwent ureteral stent insertion for the first time without a history of psychological illness were consecutively included. …”
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A longitudinal study of the 5xFAD mouse retina delineates Amyloid beta (Aβ)-mediated retinal pathology from age-related changes by Savannah A. Lynn, Sudha Priya Soundara Pandi, Aida Sanchez-Bretano, Anna-Marie Muir, Lidia Parker, David S. Chatelet, Tutte Newall, Jennifer A. Scott, Eloise Keeling, Neil R. Smyth, Jay E. Self, Andrew J. Lotery, Helena Lee, J. Arjuna Ratnayaka

“…To delineate the role of Aβ in retinopathy from age-related changes, we used transgenic 5xFAD mice in a longitudinal study to recapitulate the aged/AMD Aβ-burden of the human retina. Methods Mice were genotyped to exclude the retinal degeneration alleles Pde6b rd1 , Pde6brd8, Agouti, Tyr and Oca2. …”
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A life that’s worth living – measuring health-related quality of life among people treated for tuberculosis in Viet Nam: a longitudinal EQ-5D-5L survey by Luan Nguyen Quang Vo, Rachel Forse, Andrew James Codlin, Huy Ba Huynh, Anja Maria Christine Wiemers, Jacob Creswell, Tushar Garg, Thi Minh Ha Dang, Lan Huu Nguyen, Hoa Binh Nguyen, Luong Van Dinh, Nhung Viet Nguyen, Tom Wingfield, Kristi Sidney Annerstedt, Jad Shedrawy, Knut Lönnroth

“…We aimed to measure HRQoL among people with TB in Viet Nam at initiation and throughout treatment. Methods This study took place in four provinces from Oct-2020 to Sep-2022. …”
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Comparative the efficacy and safety of Gosuranemab, Semorinemab, Tilavonemab, and Zagotenemab in patients with Alzheimer’s disease: a systematic review and network meta-analysis of... by Wenting Cai, Wenting Cai, Hui Zhang, Hui Zhang, Yan Wu, Yan Wu, Yao Yao, Jinping Zhang

“…By investigating the effects of monoclonal antibodies on cognitive function, disease progression, and overall quality of life in patients with AD, which can provide valuable insights into their potential as a therapeutic option for this devastating neurodegenerative disorder.MethodsThe randomized controlled trials (RCTs) investigating the efficacy of Gosuranemab, Semorinemab, Tilavonemab, and Zagotenemab in Alzheimer’s disease (AD) were systematically searched across PubMed, Embase, Web of Science and Cochrane Library, up to May 2024. …”
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Effects of physically active lessons and active breaks on cognitive performance and health indicators in elementary school children: a cluster randomized trial by João Carlos N. Melo, Julian Tejada, Ellen Caroline M. Silva, José Ywgne, David N. Oliveira, Larissa Gandarela, Danilo R. Silva

“…Abstract Background This cluster‐randomized trial examined the effects of active breaks (AB) and physically active lessons (PAL) on cognitive function and health indicators in elementary school children. Methods Six schools were randomly assigned to three groups: AB group (n = 61), PAL group (n = 77), and a control group (CTL, n = 46). …”
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Risk factors for the femoral head aseptic necrosis development in patients with systemic lupus erythematosus by I. G. Kushnareva, T. V. Popkova, M. A. Makarov, A. E. Khramov

“…Objective: to identify risk factors for the development of the femoral head aseptic necrosis (FHAN) and osteoarthritis (OA) of the hip joint (HJ) in patients with systemic lupus erythematosus (SLE) according to a retrospective analysis.Material and methods.The retrospective study included data from the case histories of 103 patients with SLE who underwent total hip arthroplasty (HA) (unilateral in 82 patients, bilateral in 21). …”
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Health-related quality of life and health state utility value in idiopathic pulmonary fibrosis: a systematic review and meta-analysis by Guixiang Zhao, Siyuan Lei, Ya Li, Zhenzhen Feng, Jiansheng Li

“…This systematic review and meta-analysis of HRQoL and health state utility value (HSUV) in IPF patients and the instruments used in this assessment aimed to provide information sources and data support for the future research on IPF HRQoL and HSUV. Methods We searched the PubMed, EMBASE, Web of Science and Cochrane Library databases for studies reporting the HRQoL or HSUV of IPF patients, with the retrieval time from the establishment of each database to April 2024. …”
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The efficacy and safety of ketorolac for postoperative pain management in lumbar spine surgery: a meta-analysis of randomized controlled trials by Jianbin Guan, Ningning Feng, Kaitan Yang, Haimiti Abudouaini, Peng Liu

“…Objective We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the efficacy and safety of Ketorolac administration, both as a monotherapy and in combination with other analgesics, for managing postoperative pain in adults undergoing lumbar spinal surgery. Methods We searched PubMed, EMbase, Web of Science, EBSCO, CNKI, WanFang, VIP, and Cochrane library databases through July 2024 for randomized controlled trials (RCTs) assessing the analgesic efficacy of Ketorolac administration for postoperative pain of lumbar surgery. …”
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Genicular Nerve Ultrasound-Guided Cryoanalgesia for the Treatment of Chronic Knee Joint Pain: An Observational Retrospective Study by Giuliano Lo Bianco, Francesco Paolo D’angelo, Guillherme Ferreira Dos Santos, Agnes Stogicza, Matteo Luigi Giuseppe Leoni, Andrea M. Trescot, Robert Jason Yong, Christopher L. Robinson

“…This study aims to evaluate the effectiveness of ultrasound-guided GNCryo in patients with chronic knee pain due to primary OA or CPSP after TKA. Methods This retrospective, single-center study included 90 patients who underwent GNCryo between September 2021 and February 2023. …”
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Biomechanical and clinical comparison of different prosthetic in reconstruction following total en bloc spondylectomy in the thoracolumbar spine: based on finite element analysis a... by Zhangui Gu, Zhangui Gu, Long Ma, Long Ma, Qiang Liu, Qiang Liu, Kun Wang, Zongqiang Yang, Zongqiang Yang, Ningkui Niu, Jiandang Shi

“…ObjectivesTo analyze and compare the biomechanical differences and clinical efficacy of artificial vertebral bodies (AVBs) versus traditional titanium mesh cages (TMCs) reconstruction following total en bloc spondylectomy (TES).Materials and MethodsFinite Element Analysis: A finite element model of T12-L5 vertebrae from a healthy adult was utilized to construct two reconstruction models following L2 TES: Group A (AVB) and Group B (TMC). …”
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What is the Gold Standard for Advanced Hallux Rigidus? Minimum 10 Year Follow-Up Comparison of Interposition Arthroplasty and Arthrodesis Shows Similar Outcomes by Jeffrey E. Johnson MD, FAAOS, Andrea R. Phinney MD, Mary Hastings PT, DPT, MSCI, ATC, Hyo Jung Jeong PT, PhD, MS, Ling Chen, Andrew P. Thome MD, Jeremy J. McCormick MD, FAAOS, Jonathon D. Backus MD FAAOS

“…We hypothesized that patients undergoing MOKCIA will retain motion, but when compared to Arthrodesis at long-term follow-up, some MOKCIA patients may develop abnormal forefoot loading, toe malalignment and need revision. Methods: 26 patients who underwent a MOKCIA (n=14, 74±7 years old, 9 female, average 15 years from surgery) or an arthrodesis (n=12, 70±4 years old, 6 female, average 13 years from surgery) were recruited from a retrospective chart review (January 1, 2005, and December 31, 2018). …”
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