Good Arts, Good Mental Health®: the effectiveness of an Australian health promotion media campaign in promoting community mental wellbeing via the arts by Christina R. Davies, Melanie T. Pescud, Rhonda Clifford, Richard McGrath, Annie Thomson, Mia Jeffrey, Melissa Stoneham, Terri Pikora, Peter Wright, Sonya Girdler, Sonya Girdler, Loretta Baldassar, Stephen Clift

“…The objectives of the campaign (Wave 1) were to increase brand awareness, comprehension, and agreement with the tagline Good Arts, Good Mental Health® and empower the general population to form an intention to engage in the Arts for their mental wellbeing.MethodsThe campaign ran from August to September 2024 (4 weeks), cost AUD$198,965 (23% creative and 77% media/advertising distribution), and targeted the Western Australian (WA) general population aged 18–65 years, all genders, in both metropolitan and regional areas. …”
Get full text

A novel nomogram for predicting osteoporosis with low back pain among the patients in Wenshan Zhuang and Miao Autonomous Prefecture of China by Man Jia, Man Jia, Qinzuo Dong, Zeqin Ren, Liwei Xing, Jinjie Li, Xiaomei Wang, Shun Yu, Xiaoyan Wang, Rong Zhao, Rong Zhao

“…However, there are currently no convenient tools available to identify patients with low back pain caused by osteoporosis.MethodsWe consecutively enrolled 769 patients diagnosed with low back pain in our hospital from January 2019 to March 2024. …”
Get full text

The clinical course and outcomes following arthroscopic frozen shoulder 360° release by Brandon Ziegenfuss, BSc(Hons), MPH, Kristine Italia, MD, FPOA, Kathir Azhagan Stalin, MBBS, Sarah Whitehouse, PhD, Ashish Gupta, MBBS, MSc, FRACS, FAOrthA, Kenneth Cutbush, MBBS, FRACS, FAOrthA

“…The aim of this study is to evaluate the clinical outcomes following the FS 360° arthroscopic release. Methods: An observational prospective cohort study was conducted assessing patient-reported outcome measures (PROMs) in patients who underwent the 360° arthroscopic release between July 2013 and January 2019. …”
Get full text

L-shaped association between oxidative balance score and vision-related functional burden in adults in the United States, NHANES 2005–2008 by Juntong Li, Juntong Li, Sheng Ye, Xiang Li, Xiang Li, Hui Liu, Yue Yang, Xuelei Lu, Heyue Jin, Li Liu, Li Liu

“…ObjectiveThis study aims to investigate the relationship between oxidative balance score (OBS) and vision-related functional burden (VRFB) in US adults.MethodsThe study utilized data from two consecutive cycles of the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2008. …”
Get full text

PSMA response evaluation in follow-up PSMA-PET/CT after stereotactic ablative body radiotherapy (SABR) for oligometastases in prostate cancer by Anna-Lena Zang, Timo Maier, Sandra Freitag-Wolf, Alexander Fabian, Severin Rodler, Jürgen Dunst, David Krug, Ulf Lützen, Olaf Wittenstein

“…PSMA response was evaluated by visual and quantitative assessment of local PSMA uptake pre- and post-SABR. …”
Get full text

Could cough hypersensitivity symptom profile differentiate phenotypes of chronic cough? by Mi-Yeong Kim, Ha-Kyeong Won, Ji-Yoon Oh, Ji-Hyang Lee, Eun-Jung Jo, Sung-Yoon Kang, Ji-Ho Lee, Seung-Eun Lee, Noeul Kang, Young-Chan Kim, Hwa Young Lee, Jin An, Youngsang Yoo, Ji-Su Shim, So-Young Park, Han-Ki Park, Min-Hye Kim, Sae-Hoon Kim, Sang-Heon Kim, Yoon-Seok Chang, Sang-Hoon Kim, Byung-Jae Lee, Surinder S. Birring, Woo-Jung Song

“…This study aimed to compare symptom features, such as cough triggers and associated throat sensations, of cough hypersensitivity in patients with asthmatic chronic cough and those with refractory chronic cough (RCC). Methods Patients with chronic cough from the Korean Chronic Cough Registry were prospectively evaluated over 6 months. …”
Get full text

Quantitative tremor monitoring before, during and after MR-guided focused ultrasound thalamotomy for essential tremor with MR compatible accelerometers by Thomas Bancel, Mohammed Bashaiweth, Thomas J. Manuel, Benoît Béranger, Cécile Galléa, Mathieu Santin, Mélanie Didier, Eric Bardinet, Pierre Pouget, Mickael Tanter, Stéphane Lehéricy, Marie Vidailhet, David Grabli, Nadya Pyatigorskaya, Carine Karachi, Elodie Hainque, Jean-François Aubry

“…Currently, clinical examination is used to identify therapeutic efficacy during treatment, but MRgFUS surgery could benefit from real-time, rater-independent quantitative monitoring of tremor, such as accelerometry data.Methods Fourteen patients with medically refractory essential tremor underwent MRgFUS thalamotomy. …”
Get full text

Exploring patient preferences for intraocular lenses selection in age-related cataract: a discrete choice experiment study by Qiaolin Zhu, Qiaolin Zhu, Qiaolin Zhu, Qianqian Sun, Qianqian Sun, Qianqian Sun, Yujia Huo, Yujia Huo, Yujia Huo, Xiaoling Yang, Xiaoling Yang, Xiaoling Yang, Hehe Huang, Hehe Huang, Hehe Huang, Shanshan Qian, Shanshan Qian, Shanshan Qian, Wenjing Lin, Wentao Yan, Wentao Yan, Wentao Yan

“…IntroductionThis study investigates the preferences of cataract patients in East China regarding intraocular lenses (IOLs).MethodsA Discrete Choice Experiment (DCE) was conducted using a questionnaire that included various IOLs attributes. …”
Get full text

Interrelationships of stress, burnout, anxiety, depression, quality of life and suicidality among Chinese residents under Standardized Residency Training: a network analysis by Zejun Li, Min Wu, Xiaoyu Zhang, Kewen Yan, Xin Wang, Huixue Xu, Peizhen Li, Yueheng Liu, Qijian Deng, Xueyi Li, Qianjin Wang, Manyun Li, Yunfei Wang, Yuzhu Hao, Li He, Yi-Yuan Tang, Tieqiao Liu, Pu Peng, Qiuxia Wu

“…This study aims to investigate the symptom network of stress, burnout, anxiety, depression (SBAD) and adverse personal outcomes in this cohort.Methods From October 2020 to April 2022, 994 physicians were recruited across China through snowball sampling. …”
Get full text

Sex differences in resting skeletal muscle and the acute and long-term response to endurance exercise in individuals with overweight and obesity by Simon I. Dreher, Thomas Goj, Christine von Toerne, Miriam Hoene, Martin Irmler, Meriem Ouni, Markus Jähnert, Johannes Beckers, Martin Hrabě de Angelis, Andreas Peter, Anja Moller, Andreas L. Birkenfeld, Annette Schürmann, Stefanie M. Hauck, Cora Weigert

“…As biological sex impacts glucose and fatty acid handling in skeletal muscle, we hypothesized sex differences at the transcriptomic and proteomic level in the acute response to exercise and after an 8-week exercise intervention. Methods: We analyzed skeletal muscle biopsies from 25 sedentary subjects (16f/9 m) with overweight and obesity using transcriptomics and proteomics at baseline, after acute exercise, and following an 8-week endurance training program. …”
Get full text

The impact of physical activity on progression-free and overall survival in metastatic breast cancer based on molecular subtype by Philipp Ziegler, Andreas D. Hartkopf, Markus Wallwiener, Lothar Häberle, Hans-Christian Kolberg, Peyman Hadji, Hans Tesch, Johannes Ettl, Diana Lüftner, Volkmar Müller, Laura L. Michel, Erik Belleville, Pauline Wimberger, Carsten Hielscher, Hanna Huebner, Sabrina Uhrig, Lena A. Wurmthaler, Carolin C. Hack, Christoph Mundhenke, Christian Kurbacher, Peter A. Fasching, Rachel Wuerstlein, Michael Untch, Wolfgang Janni, Florin-Andrei Taran, Michael P. Lux, Diethelm Wallwiener, Sara Y. Brucker, Tanja N. Fehm, Andreas Schneeweiss, Chloë Goossens

“…Therefore, we here evaluated the effect of physical activity on progression-free and overall survival (PFS, OS) in metastatic breast cancer, specifically looking at molecular subtypes. Methods International Physical Activity Questionnaire (IPAQ) questionnaires, filled out by patients enrolled in the prospective PRAEGNANT registry (NCT02338167; n = 1,270) were used to calculate metabolic equivalent task (MET) minutes, which were subsequently categorized into low (n = 138), moderate (n = 995) or high IPAQ categories (n = 137). …”
Get full text

Early detection to improve outcome in people with undiagnosed psoriatic arthritis: the PROMPT research programme including RCT by Neil McHugh, Laura Bojke, Mel Brooke Turfrey, Rachel Charlton, Myka Ransom, Laura C Coates, Howard Collier, Claire Davies, Emma Dures, Philip Helliwell, Jana James, Anya Lissina, Vishnu B Madhok, Alison L Nightingale, Jonathan Packham, Catherine Smith, Eldon Spackman, Cerys Tassinari, William Tillett, Sarah T Brown

“…BN models may be a useful method to identify clusters of symptoms that predict PsA with reasonable accuracy. …”
Get full text

Evaluation of multidrug-resistant bacteria and their molecular mechanisms found in small animal veterinary practices in Portugal by Joana Moreira da Silva, Joana Moreira da Silva, Juliana Menezes, Juliana Menezes, Juliana Menezes, Laura Fernandes, Laura Fernandes, Cátia Marques, Cátia Marques, Cátia Marques, Sofia Santos Costa, Dorina Timofte, Andreia J. Amaral, Andreia J. Amaral, Andreia J. Amaral, Constança Pomba, Constança Pomba, Constança Pomba

“…The goal of our work was to evaluate the environmental contamination and staff carriage by MDROs in veterinary practices across Portugal.MethodsFourteen SAVPs were enrolled. Environmental samples were collected from critical areas such as operating room, wards and pre-operative area. …”
Get full text

Prospective study of continuous rhythm monitoring in patients with early post-infarction systolic dysfunction: clinical impact of arrhythmias detected by an implantable cardiac mon... by Jesus Hernandez-Hernandez, Ana Martin-Garcia, Javier Jimenez-Candil, Pedro L Sanchez, Carlos González-Juanatey, Javier García-Fernández, Alba Cruz-Galban, Olga Duran-Bobin, Javier Garcia-Seara, Teba Gonzalez-Ferrero, Jose Morinigo, Manuel Sanchez-Garcia, Gonzalo Fernandez-Palacios, Jose Seijas-Amigo, Juliana Elices, Javier Portales-Fernandez, Francisco Martin-Herrero, Ana García-Campos, Jose A Perez-Rivera, Marta Alonso-Fernandez-Gatta, Alfonso Macías, Paloma Perez-Espejo

“…Among patients with post-infarction left ventricular dysfunction, modern implantable cardiac monitoring devices (ICM) allow a unique opportunity to determine in real-time the burden of non-sustained ventricular tachycardias and their relationship to the subsequent occurrence of sustained or symptomatic events.Methods and analysis Approximately 200 patients with left ventricular ejection fraction (LVEF) equal to or less than 40% after acute myocardial infarction will be included in the study. …”
Get full text

Maltreatment and parenting in youth with primary and secondary callous‐unemotional traits: Anxiety matters by Jessica J. Todorov, Gregor Kohls, Ruth Pauli, Jack Rogers, Anka Bernhard, Katharina Ackermann, Nora M. Raschle, Jules R. Dugre, Aranzazu Fernandez‐Rivas, Miguel Angel Gonzalez‐Torres, Amaia Hervas, Areti Smaragdi, Karen Gonzalez, Ágnes Vetró, Dimitris Dikeos, Arne Popma, Christina Stadler, Kerstin Konrad, Christine M. Freitag, Graeme Fairchild, Rory T. Devine, Stephane A. De Brito

“…Youth with primary and secondary CU traits were equally high on levels of abuse, neglect, and maladaptive parenting (all p values >0.05). …”
Get full text

Impact of multidimensional assessment on anti-fracture treatment decisions in patients with fragility hip fractures within a Fracture Liaison Service by Chiara Ceolin, Stefania Sella, Cristina Simonato, Ester Bukli, Giulia Bano, Valentina Camozzi, Anna Bertocco, Marco Onofrio Torres, Alberta Cecchinato, Martin Diogo, Mor Peleg Falb, Francesca Guidolin, Maria Grazia Rodà, Michele Cannito, Antonio Berizzi, Andrea Venturin, Vito Cianci, Elisa Pala, Mariachiara Cerchiaro, Deris Gianni Boemo, Maria Vittoria Nesoti, Gaetano Paride Arcidiacono, Paolo Simioni, Pietro Ruggieri, Giuseppe Sergi, Sandro Giannini, Marina De Rui, on behalf of the Hip-POS working group

“…This study aimed to identify the primary factors influencing anti-fracture therapy decisions in older patients with fragility fractures, using a multidimensional geriatric assessment approach integrated into our FLS program. Methods A retrospective analysis was conducted on patients aged 65 and above with hip fractures admitted to Azienda Ospedale-Università Padova. …”
Get full text

A Multicenter Randomized Double-Blind Vehicle-Controlled Parallel Group Phase 2 Study Evaluating the Efficacy and Safety of GN-037 Cream in Patients with Mild-to-Moderate Plaque Ps... by Burhan Engin, Müge Güler Özden, Özge Sevil Karstarlı Bakay, Selda Pelin Kartal, İlkin Zindancı, Salih Levent Çınar, Recep Dursun, Gizem Pehlivan Ulutaş, Tuğba Özkök Özkök Akbulut, Fatma Aslı Hapa, Emel Bülbül Başkan, Mehmet Melikoğlu, Algün Polat Ekinci, Neslihan Demirel Öğüt, Pelin Hızlı, Zafer Türkoğlu, Özlem Su Küçük, Zeynep Topkarcı, Ümit Türsen, Filiz Canpolat, Hanife Uçgun, Şirin Yaşar, Selami Aykut Temiz, Asena Çiğdem Doğramacı, Sedat Altuğ, Serhat Kozlu, Nadir Ulu, Server Serdaroğlu

“…The present multicenter randomized double-blind vehicle-controlled parallel group phase 2 study aimed to investigate the efficacy and safety of GN-037 in patients with mild-to-moderate plaque psoriasis (MMPP). Methods Patients (n = 190) were randomized (2:2:1) to receive GN-037 or CP or vehicle (V) cream twice daily to a selected target body lesion for 4 weeks. …”
Get full text

Optimizing treatment for depression in primary care using psychotherapy versus antidepressant medication in a low-resource setting: protocol for the OptimizeD randomized controlled... by Julia R. Pozuelo, Anuja Lahiri, Rahul S. P. Singh, Arvind Kushwah, Mimansa Khanduri, Akanksha Shukla, Azaz Khan, Sruthi G., Varun Shende, Yashika Parashar, Yashwant K. Mehra, Anant Bhan, Ronald C. Kessler, Daisy R. Singla, John A. Naslund, Karmel W. Choi, Pim Cuijpers, Robert DeRubeis, Mohammad M. Herzallah, Chunling Lu, Jordan W. Smoller, Tyler J. VanderWeele, Abhijit R. Rozatkar, Tamonud Modak, Michelle Melwyn Joel, Debasis Biswas, Shubham Atal, Umay Kulsum, Steven D. Hollon, Vikram Patel

“…The Optimizing Depression (OptimizeD) trial aims to explore whether different patients respond differently to behavioral activation therapy versus antidepressant medication and if providing each patient with their optimal treatment improves outcomes in primary care. Methods We plan to randomize 1,500 patients with moderate to severe depression (defined as a Patient Health Questionnaire [PHQ-9] score ≥ 10) from primary healthcare settings in Bhopal, India, with equal allocation either to a culturally adapted behavioral activation therapy delivered by trained counselors (Healthy Activity Program) or to antidepressant medication (fluoxetine). …”
Get full text

Combination cancer immunotherapy targeting TNFR2 and PD-1/PD-L1 signaling reduces immunosuppressive effects in the microenvironment of pancreatic tumors by Yi Duan, Wen Chen, Jian Xu, Xiaoyu Zhang, Xiaozhen Zhang, Tingbo Liang, Xueli Bai, Mengyi Lao, Hanshen Yang, Muchun Li, Honggang Ying, Lihong He, Kang Sun, Chengxiang Guo, Haitao Jiang

Get full text

HHLA2 and PD-L1 co-expression predicts poor prognosis in patients with clear cell renal cell carcinoma by Xu Chen, Hai Huang, Qiong Wang, Qiang-Hua Zhou, Kai-Wen Li, Hai-Xia He, Sheng-Meng Peng, Shi-Rong Peng, Ze-An Li, Yi-Ran Tao, Wen-Li Cai, Ran-Yi Liu

Get full text