Liposomal bupivacaine versus conventional anesthetics in adductor canal block for total knee arthroplasty: a meta-analysis of randomized controlled trials by Xiaoli Ye, Kaixi Shang, Lina Zhao, Quan Liang, Huanzhen Luo, Jing Shi

“…This meta-analysis aimed to compare LB with conventional anesthetics in ACB for TKA. Methods: Following PRISMA guidelines, we systematically searched PubMed, EMBASE, Cochrane Library, and Web of Science up to December 15, 2024, for randomized controlled trials (RCTs) evaluating adult patients undergoing TKA who received ACB with either LB or conventional anesthetics. …”
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Fu’s subcutaneous needling for knee osteoarthritis: a systematic review and meta-analysis by Xiaohu Zhao, Jingxuan Liu, Dake Li, Shangkun Si, Xuanhe Tian, Deke Zhang, Ping Jiang, Ping Jiang

“…The objective of this systematic review is to compare the efficacy and safety of FSN to routine acupuncture therapy (RAT) for KOA.MethodsChina National Knowledge Infrastructure, VIP, China Biomedical Literature Database, Wanfang Medical, Embase, PubMed, Ovid, and the Cochrane Library were searched from inception to March 2025, and randomized controlled trials on FSN for KOA were included. …”
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Analgesic application of a novel non-steroidal anti-inflammatory drug imrecoxib after total knee arthroplasty: a prospective randomized controlled study by Guoyang Bai, Xiangxiang Sun, Qunli Dou, Bowei Li, Kai Qin, Xiaobo Sun, Jianbing Ma, Chao Xu, Yuanchi Huang

“…Therefore, this study aims to explore the clinical efficacy and safety of imrecoxib in postoperative analgesia after TKA. Methods The 120 patients were randomly assigned to two groups. …”
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The study of functional asymmetry in students and schoolchildren practicing martial arts by Vyacheslav V. Romanenko, Olha O. Podrihalo, Leonid V. Podrigalo, Sergii S. Iermakov, Zhanna V. Sotnikova-Meleshkina, Oksana V. Bobrova

“…The study of functional asymmetry in students and schoolchildren practicing martial arts using a computer test. Material and Methods. The study involved students and schoolchildren (n = 38) practicing the martial arts (taekwondo, karate). …”
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The efficacy of core stabilization exercise in mild and moderate adolescent idiopathic scoliosis: a systematic review and meta-analysis by Xiaomei Liu, Yanyang Wang, Min Liu, Yu Zhang, Qiang Wu, Qian Wang

“…Objective To determine the efficacy of CSE in the patients with AIS in comparison with different intervention programs. Methods A comprehensive search was conducted across PubMed, Embase, The Cochrane Library, Web of Science, Wan Fang, Wei Pu, and CNKI databases, encompassing literature from their inception through December 31st, 2024. …”
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Reduction in Artemisia Pollen-Specific IgE Levels During House Dust Mite Allergen Immunotherapy in Polysensitized Allergic Rhinitis Patients: A Three-Year Retrospective Study in No... by Sun X, Li X, Gao T, Liu P, Liu N, Jin P, Zhi L

“…This study investigates the impact of house dust mite AIT on IgE responses to both dust mites and non-target allergens, specifically Artemisia pollen, in polysensitized allergic rhinitis patients.Methods:  This retrospective study included polysensitized patients aged 18 or older with a diagnosis of allergic rhinitis or rhinitis with asthma and positive IgE for both house dust mites and Artemisia pollen. …”
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Study of anatomy-diagnostic features of leaves of <i>Cynara scolymus</i> L. grown under the conditions of the Kyrgyz Republic by S. C. Chubakova, N. T. Farmanova, N. V. Bobkova, T. A. Mamatov

“…To study the macro and micromorphological characters of C. scolymus leaves for introduction into medical practice.Materials and methods. Dried leaves of artichoke (Cynara scolymus L.), collected in the flowering phase (June) of 2023, in the Osh region of the Kyrgyz Republic, were used as the object of the study. …”
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Features of ankylosing spondylitis at different stages in men and women by I. A. Cherentsova, E. N. Otteva

“…The incidence of ankylosing spondylitis (AS) has recently increased with a substantial rise in the proportion of female patients, making this investigation relevant.Objective: to investigate the clinical and laboratory parameters of inflammatory activity and functional status in male and female patients with AS at different stages of the disease.Patients and methods. Examinations were performed in 119 patients (82 men and 37 women) (mean age, 36.4±0.9 years) with AS and 34 patients (24 men and 10 women) (mean age 27.0±1.6 years) with non-radiographic axial spondyloarthritis (nr-axSpA). …”
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Treatment Planning Strategies for Interstitial Ultrasound Ablation of Prostate Cancer by Pragya Gupta, Tamas Heffter, Muhammad Zubair, I-Chow Hsu, E. Clif Burdette, Chris J. Diederich

“…This involves the integration with a FDA 510(k) cleared catheter-based ultrasound interstitial applicators and delivery system. Methods: A 3D generalized &#x201C;prostate&#x201D; model was developed to generate temperature and thermal dose profiles for different applicator operating parameters and anticipated perfusion ranges. …”
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Spatiotemporal analysis of rainfall variability using satellite precipitation in watersheds by M.D. Syaifullah, A. Purwandani, M. Kudsy, Tukiyat , S. Tikno, A.E. Sakya, F.H. Widodo, S. Bahri, Muktiyono

“…This study aims to investigate how geomorphological and topographical differences across the Toba-Asahan, Brantas, and Larona-Malili watersheds in Indonesia influence rainfall distribution and trends, in order to support adaptive and sustainable watershed management.METHODS: This study analyzes rainfall variability in three distinct Indonesian watersheds, Toba-Asahan, Brantas, and Larona-Malili, using climate hazards group infrared precipitation with Station version 2 satellite precipitation data. …”
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Hymecromone Administration in Real Clinical Practice: Results of the Prospective Multicentre Observational Study in the Republic of Kazakhstan by A. V. Nersesov, D. A. Kaybullaeva, V. S. Rakhmetova, I. A. Lozinskaya, A. K. Kurmangalieva, V. S. Ayupova, A. B. Orazbaeva, A. K. Kanabaeva, Yu. O. Shulpekova

“…The objectives of the study included collection of clinical characteristics of patients, evaluation of Odeston effects in treatment of biliary pain and changes in the gallbladder emptying, evaluation of compliance to therapy, and treatment effect satisfaction.Materials and methods. The study was conducted from July 2020 to April 2021 at the premises of 60 study sites in 4 cities of the Republic of Kazakhstan. …”
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Keratinocyte-derived VEGF-A is an essential pro-migratory autocrine mediator, acting through the KDR/GEF-H1/RhoA pathway by Vida Maksimoska, Vida Maksimoska, Qinghong Dan, Neetu Rambharack, Neetu Rambharack, Katalin Szászi, Katalin Szászi, Katalin Szászi, Katalin Szászi

“…The overall objective of the current study was to explore the connection between inflammation-induced keratinocyte mediator release and enhanced migration, and to identify specific RhoA regulators involved.MethodsThe study was done using HaCat cells and primary adult keratinocytes. …”
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A multicenter, prospective, randomized trial of the efficacy and safety of Alflutop® in an alternating dosing regimen versus the standard one. Communication 2: Evaluation of the ef... by E. P. Sharapova, L. I. Alekseeva, E. A. Taskina, N. G. Kashevarova, S. G. Anikin, E. A. Strebkova, A. M. Lila, V. I. Mazurov, N. A. Shostak, E. I. Shmidt, E. P. Ilivanova

“…From this point of view, therapy seems to be relevant when the latter involves drugs that have both symptom- and structure-modifying properties and have a high safety profile.Objective: to compare the safety of alternating and standard treatment regimens with Alflutop® in patients with knee OA.Patients and methods. 130 patients were enrolled in the trial who had Kellgren-Lawrence Grade II–III primary tibiofemoral knee OA with pain intensity on walking ≥40 mm on a visual analogue scale and who needed to take nonsteroidal anti-inflammatory drugs (≥30 days in the previous 3 months). …”
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Exploring Ocular Fundus Changes and Biochemical Correlations in Pregnancy-Induced Hypertension: Two Year Observational Study in Tertiary Care Center, India by A. M. Raja, G Seema

“…This research underscores the value of ocular assessments in the management of PIH, supporting maternal health not only during pregnancy but also in the postpartum period. Materials and Methods: This cross-sectional study included 200 antenatal women diagnosed with PIH attending a tertiary care center in Palakkad, Kerala. …”
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Septal panniculitis as manifestation of COVID-19: own data by O. N. Egorova, R. G. Goloeva, D. I. Abdulganieva

“…Objective: to study the clinical and laboratory features of erythema nodosum (EN) in a cohort of patients with COVID-19 referred to a rheumatological center.Patients and methods. During 2020–2021 years 21 patients (18 women and 3 men, mean age 43.2±11.4 years) with EN and polyarthralgia/arthritis were examined. …”
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Evaluation of enhanced recovery after surgery combined with percutaneous acupoint electrical stimulation in perioperative nursing of patients with gastric cancer (快速康复护理联合经皮穴位电刺激在胃... by HUANG Yanying (黄艳颖), LI Wenjuan (李文娟)

“…Objective To investigate the effect of enhanced recovery after surgery combined with percutaneous acupoint electrical stimulation in perioperative nursing of patients with gastric cancer. Methods Totally 52 patients undergoing surgery for gastric cancer were randomly divided into the control group and study group, with 26 cases in each group. …”
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Clinical and Economic Outcomes of Intradiscal Injection of Condoliase for a Treatment of Lumbar Disc Herniation with Severe Low Back Pain: A Multicenter Study by Takashi Hirai, Takuya Takahashi, Yohei Takahashi, Kota Watanabe, Tomohiro Banno, Kyohei Sakaki, Yoshiyasu Arai, Yuichi Takano, Yawara Eguchi, Yuki Taniguchi, Satoshi Maki, Yasuchika Aoki, Shunichi Fujii, Kentaro Sakaeda, Yu Matsukura, Tsutomu Akazawa, Akihito Minamide, Hidetoshi Nojiri, Kenichiro Sakai, Satoshi Kato, Koji Tamai, Hidekazu Suzuki, Masayuki Miyagi, Hiroyuki Sato, Toshitaka Yoshii, Hiroshi Yamada, Takashi Kaito, Yutaka Hiraizumi, Masatsune Yamagata, Masaya Nakamura, Akihiro Hirakawa, Naofumi Hosogane, Seiji Ohtori

“…In this multicenter study, the effectiveness of condoliase injection for reducing severe LBP in patients with LDH was evaluated. Methods: This retrospective study involved patients treated with intradiscal condoliase injection for LDH at nine participating centers. …”
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Evaluating the Performance and Potential Bias of Predictive Models for Detection of Transthyretin Cardiac Amyloidosis by Jonathan Hourmozdi, MD, MSAI, MA, Nicholas Easton, MSAI, Simon Benigeri, MSAI, James D. Thomas, MD, Akhil Narang, MD, David Ouyang, MD, Grant Duffy, BS, Ross Upton, PhD, Will Hawkes, PhD, Ashley Akerman, PhD, Ike Okwuosa, MD, Adrienne Kline, MD, PhD, Abel N. Kho, MD, Yuan Luo, PhD, Sanjiv J. Shah, MD, Faraz S. Ahmad, MD, MS

“…Bias auditing met fairness criteria for equal opportunity among patients who identified as Black. …”
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Characterizing anticoagulation reversal practices in Colombia: Initial insights from a national registry by Sebastián Seni-Molina, Santiago Posso Marín, Juan Esteban Masmela, María Camila Naranjo-Ramírez, Arturo D. Mora, Juliana María Gutiérrez-Posso, Julio Diez-Sepúlveda, Juan David Victoria-Salcedo, Ana Cristina Montenegro Arenas, Camilo Andrés Rueda Ortiz, Edgar David Gómez Lahitton, Hoover O. León-Giraldo, Juan Esteban Gómez-Mesa

“…Despite its importance, evidence in Colombia is limited. Methods: RECCANT-AR (Registro Colombiano de Clínicas de Anticoagulación y el Uso de Agentes Reversores) is a multicenter, observational, ambispective study analyzing anticoagulated patients requiring reversal therapy due to bleeding or procedural needs. …”
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Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling by Asra Asgharzadeh, Mubarak Patel, Martin Connock, Sara Damery, Iman Ghosh, Mary Jordan, Karoline Freeman, Anna Brown, Rachel Court, Sharin Baldwin, Fatai Ogunlayi, Chris Stinton, Ewen Cummins, Lena Al-Khudairy

“…What is the cost-effectiveness of HCL for managing glucose in people who have type 1 diabetes and are having difficulty managing their condition despite prior use of at least one of the following technologies: CSII, rt-CGM, isCGM? Methods Systematic review methods followed the principles outlined in the Cochrane Handbook. …”
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