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31081
Diagnostic Accuracy of Non-Invasive Diagnostic Tests for Nonalcoholic Fatty Liver Disease: A Systematic Review and Network Meta-Analysis
Published 2025-01-01“…We aimed to assess and compare the diagnostic accuracy of various NITs for NAFLD using network meta-analysis (NMA).Materials and Methods: We conducted a systematic search in seven databases up to April 2024 to identify studies evaluating the diagnostic values of NITs, with liver biopsy as the gold standard. …”
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31082
Associations between the Chinese Visceral Adiposity Index and the Self-Reported Menopausal Status: Results from Two Nationally Representative Population-Based Studies
Published 2025-05-01“…This study explores the Chinese visceral adiposity index (CVAI) as a potential indicator of menopausal status to aid in disease prevention.Patients and Methods: A cohort of 404 premenopausal Chinese women aged 45 years and above, from the China Health and Retirement Longitudinal Study (CHARLS), was included. …”
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31083
Serum Folic Acid Predicted Pre-Operative Aortic Rupture in Symptomatic Aortic Aneurysm Dissection: A Prospective, Single-Center, Observational Study
Published 2025-05-01“…The aim of this study was to evaluate the predictive value of serum folic acid level for pre-operative adverse events in patients with symptomatic aortic aneurysm/aortic dissection.Methods and Results: Patients with symptomatic aortic aneurysm/aortic dissection, presenting to the emergency department (ED), were enrolled in the study. …”
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31084
PREDICATIVE ARRANGEMENT OF NATIONAL ANTHEM TEXTS IN ENGLISH- AND GERMAN- SPEAKING COMMUNITIES
Published 2025-06-01“…This involves the comprehensive application of relevant linguistic methods (analytical-descriptive, structural semantic, functional grammatical, pragmalinguistic), techniques (classification, systematization), and procedures (contextual analysis, quantitative calculations). …”
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31085
Association Between Pain and Frailty in Middle-Aged and Older Patients: The Mediating Roles of Sleep and Mood
Published 2025-06-01“…This study aimed to investigate the association between pain and frailty, with a particular focus on the mediating roles of sleep and mood.Patients and Methods: A cross-sectional study was conducted involving 244 middle-aged and older participants in local hospital. …”
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31086
Plasma Aldosterone Elevation in Hypertensive Patients and Association with Urinary Stone Formation: A Large-Scale Population Study from Northwest China
Published 2025-05-01“…Therefore, this study aimed to investigate the relationship between PAC levels and urinary stones, including their subtypes, in patients with hypertension.Methods: This large-scale study included a total of 35161 hypertensive patients. …”
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31087
Effects of Dexmedetomidine as an Adjuvant in Preoperative Ultrasound-Guided Internal Branch of Superior Laryngeal Nerve Block on Postoperative Sore Throat and Hemodynamics in Patie...
Published 2025-01-01“…In this first randomized controlled trial to date, we aimed to investigate the effects of US-guided iSLNB, with or without perineural dexmedetomidine, on the incidence and severity of POST following DLTs.Methods: A total of 159 patients were randomly assigned to three groups: control, bilateral US-guided iSLNB (2 mL 0.20% ropivacaine + 1 mL saline on each side), and bilateral US-guided iSLNB combined with perineural dexmedetomidine group (2 mL 0.20% ropivacaine + 1 mL 0.5 μg·kg− 1 dexmedetomidine on each side). …”
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31088
Reflecting on the Implementation of United Kingdom (UK) General Practitioner Training Models in China: Highlights From a Train-the-Trainer Pilot Program
Published 2025-06-01“…This program aims to reflect on the effective implementation of innovative training models in the context of Chinese GPs training system, ultimately aiming to improve the trainers’ capability in training the future Chinese general practitioners.Methods: This study was a cross-sectional survey with an online questionnaire seeking feedback from the GP teachers and trainers who attended the train-the-trainer program featuring co-designed online and offline teaching.Results: All participants were general practitioners; average age 42.5± 5.41 years, including 65% female, 65% consultant general practitioners, 60% general practitioners with PhD, average years of clinical practice being 17.7± 6.96, average years of teaching being 6.0± 1.41, average hours of teaching weekly being 2.1± 0.85, and average number of residents trained being 39.6± 51.87. …”
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31089
Efficacy and Safety of Eravacycline Combination Therapy for Carbapenem-Resistant Acinetobacter baumannii Pneumonia in ICU Patients: A Retrospective Study
Published 2025-06-01“…This study compares eravacycline with tigecycline for CRAB pneumonia in ICU patients.Methods: This retrospective study analyzed 65 ICU patients with CRAB pneumonia treated at Henan Provincial People’s Hospital from September 2023 to March 2024; the clinical efficacy and adverse reactions of eravacycline and tigecycline as target therapies were compared.Results: Both CRAB pneumonia cohorts exhibited more than 50% co-infection rates, predominantly Aspergillus and Klebsiella pneumoniae. …”
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31090
Inflammatory Burden Index: A Superior Prognostic Biomarker of Systemic Inflammation in Patients on Peritoneal Dialysis
Published 2024-12-01“…The purpose of this study was to evaluate the prognostic value of various systemic inflammation biomarkers and to identify the optimal one in PD patients.Patients and Methods: This longitudinal study involved 3,225 patients undergoing PD across China. …”
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31091
Low-dose Esketamine combined with Propofol in microscopic pediatric strabismus surgery: a randomized controlled study
Published 2025-05-01“…Abstract Objective To observe the effect of low-dose esketamine combined with propofol in pediatric strabismus surgery. Methods A total of 84 children aged 3–15 years, regardless of gender, with a BMI of 13–26 kg/m2, ASA grade I or II, were selected for elective microscopic strabismus surgery and divided into two groups based on the randomized numerical table: esketamine group (group E) and propofol group (group C), with 42 patients in each group. …”
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31092
Machine Learning and Experimental Validation Reveal MYH11 as a Novel Prognostic Biomarker and Therapeutic Target in Bladder Cancer
Published 2025-06-01“…This study aimed to explore the potential molecular mechanisms of BCa using multi-omics and single-cell analysis.Methods: First, differential analysis of transcriptome data related to BCa from public databases was performed, and a risk model was then developed using 101 different machine learning algorithms to determine prognostic genes, followed by independent prognostic analysis to construct a nomogram. …”
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31093
Chaihu-Shugan-San Ameliorated Osteoporosis of Mice with Depressive Behavior Caused by Chronic Unpredictable Mild Stress via Repressing Neuroinflammation and HPA Activity
Published 2024-12-01“…This study aimed to explore the development of osteoporosis in depressive mice model and investigate the beneficial effects of the classical herbal formula Chaihu-Shugan-San (CHSG) on the brain and bone.Methods: CHSG powder was prepared by spray-drying following extraction with water. …”
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31094
Factors Associated with Nursing Intention of Discharged Patients With Drainage Tubes During Transitional Care: a Case–Control Study
Published 2025-03-01“…Xiaoying Ding,* Weijie Jiao,* Xue Gong, Yuanyuan Sun, Lin Sang, Ming Yu Department of Ultrasound, Xijing Hospital, The Fourth Military Medical University, Xi’an, Shaanxi, 710032, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ming Yu, Department of Ultrasound, Xijing Hospital, The Fourth Military Medical University, No. 127 Changle West Road, Xi’an, Shaanxi, 710032, People’s Republic of China, Email yumingfmmu@126.comPurpose: This study aimed to assess the crucial factors that contribute to the self-nursing intention of discharged patients with drainage tubes, with a specific emphasis on percutaneous surgeries.Patients and Methods: A case–control study was conducted in accordance with the EQUATOR-STROBE statement. …”
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31095
NRF2 Deficiency in Bladder Epithelial Cells Owing to Ubiquitination by N6-Methyladenosine-Modified TRIM21 Induces Oxidative Stress and Inflammation to Aggravate IC/BPS
Published 2025-08-01“…This study aimed to investigate the effects of nuclear factor erythroid 2-related factor 2 (NRF2) on IC/BPS and the potential molecular mechanisms.Methods: Bladder mucosal biopsies from IC/BPS patients were subjected to RT-qPCR and immunoblotting to quantify NRF2 mRNA/protein expression. …”
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31096
AI in Home Care—Evaluation of Large Language Models for Future Training of Informal Caregivers: Observational Comparative Case Study
Published 2025-04-01“…Furthermore, it seeks to identify specific domains where LLMs show the most promise and where improvements are necessary to optimize their reliability for caregiver training. MethodsAn observational, comparative case study evaluated 3 LLMs—GPT-3.5, GPT-4o, and Microsoft Copilot—in 10 home care scenarios. …”
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31097
The impact of the universities closure on physical activity and academic performance in physical education in university students during the COVID-19 pandemic
Published 2021-02-01“…The purpose of the research was to assess overall and sport/fitness PA level and academic performance in PE in a sample of university students pre- to post-cancellation of face-to-face PE classes due to the COVID-19 pandemic. Material and Methods. Participants (n=209) – university students (19-20 years old). …”
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31098
Predictive Scores for Identifying Chronic Opioid Dependence After General Anesthesia Surgery
Published 2024-12-01“…Mingyang Sun,1,2,* Wan-Ming Chen,3,4,* Zhongyuan Lu,1,2 Shuang Lv,1,2 Ningning Fu,1,2 Yitian Yang,1,2 Yangyang Wang,1,2 Mengrong Miao,1,2 Szu-Yuan Wu,5– 11 Jiaqiang Zhang1,2 1Department of Anesthesiology and Perioperative Medicine, People’s Hospital of Zhengzhou University, Henan Provincial People’s Hospital, Zhengzhou, Henan, People’s Republic of China; 2Academy of Medical Sciences of Zhengzhou University, Zhengzhou, Henan, People’s Republic of China; 3Graduate Institute of Business Administration, College of Management, Fu Jen Catholic University, Taipei, Taiwan; 4Artificial Intelligence Development Center, Fu Jen Catholic University, Taipei, Taiwan; 5Department of Food Nutrition and Health Biotechnology, College of Medical and Health Science, Asia University, Taichung, Taiwan; 6Big Data Center, Lo-Hsu Medical Foundation, Lotung Poh-Ai Hospital, Yilan, Taiwan; 7Division of Radiation Oncology, Lo-Hsu Medical Foundation, Lotung Poh-Ai Hospital, Yilan, Taiwan; 8Department of Healthcare Administration, College of Medical and Health Science, Asia University, Taichung, Taiwan; 9Cancer Center, Lo-Hsu Medical Foundation, Lotung Poh-Ai Hospital, Yilan, Taiwan; 10Centers for Regional Anesthesia and Pain Medicine, Taipei Municipal Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; 11Department of Management, College of Management, Fo Guang University, Yilan, Taiwan*These authors contributed equally to this workCorrespondence: Szu-Yuan Wu, College of Medical and Health Science, Asia University, Taichung, Taiwan; Director, Big Data Center, Lo-Hsu Medical Foundation, LotungPoh-Ai Hospital, No. 83, Nanchang St., Luodong Township, Yilan County, 265, Taiwan, Email szuyuanwu5399@gmail.com Jiaqiang Zhang, Department of Anesthesiology and Perioperative Medicine, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, No. 7 Weiwu Road, Jinshui District, Zhengzhou, Henan, 450003, People’s Republic of China, Email jiaqiang197628@163.comPurpose: To address the prevalence and risk factors of postoperative chronic opioid dependence, focusing on the development of a predictive scoring system to identify high-risk populations.Methods: We analyzed data from the Taiwan Health Insurance Research Database spanning January 2016 to December 2018, encompassing adults undergoing major elective surgeries with general anesthesia. …”
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31099
Activation of TLR4/CCL2 in Intact Neurons Drives Radicular Injury-Induced Global Nerve Trunk Hypersensitivity in Radiculopathy Preclinical Models
Published 2025-08-01“…However, the underlying mechanisms remain unclear.Methods: An L5 spinal nerve compression rat model was established. …”
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31100
The effects of normal and interrupted sleep combined with acute caffeine supplementation on some immune system indices and anaerobic power in male athletes
Published 2024-08-01“…In the current study, the effects of normal and interrupted sleep combined with acute caffeine supplementation on some immune system indices and anaerobic power in male athletes were examined.Materials and Methods: This semi-experimental study was conducted using a randomized design. …”
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