A Contribution of Shortest Paths Algorithms to the NetworkX Python Library by Miguel Cruz, Rui Carvalho, André Costa, Luis Pinto, Luis Dias, Paulino Cerqueira, Rodrigo Machado, Tiago Batista, Pedro Castro, Jorge Ribeiro

“…We have also done the benchmarking of the A*, comparing it with the new ones, and concluded the better efficiency of the A* extensions in tri-objective scenario parameters (length, cost and toll). …”
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EXERCISE THERAPY ON UNSTABLE SUPPORT AND HYDROKINETIC THERAPY IN THE REHABILITATION OF PATIENTS WITH BACK PAIN by E. V. Filatova, O. A. Boulakh, E. V. Polkovnikova, N. M. Privalova, Kh. M. Malaev

“…A comparative analysis of the efficiency of different procedures of exercise therapy is carried out: hydrokinesitherapy and therapeutic gymnastics with the use of exercise on an unstable support (stabiloplatform) depending on the sex of patients.Materials and methods. …”
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Time Zero for Net Zero: A Coal Mine Baseline for Decarbonising Heat by Alison A. Monaghan, Luke Bateson, Adrian J. Boyce, Neil M. Burnside, Rebecca Chambers, Julia R. de Rezende, Eilidh Dunnet, Paul A. Everett, Stuart M. V. Gilfillan, Muhammad S. Jibrin, Gareth Johnson, Richard Luckett, Donald John MacAllister, Alan M. MacDonald, John W. Moreau, Laura Newsome, Alessandro Novellino, Barbara Palumbo-Roe, Ryan Pereira, Douglas Smith, Mike J. Spence, Vanessa Starcher, Helen Taylor-Curran, Christopher H. Vane, Thomas Wagner, David B. Walls

“…Integration of the wide array of time zero observations and understanding of coupled subsurface processes has significant potential to inform development of efficient and resilient geothermal infrastructure and to inform the design of fit-for-purpose monitoring approaches in the quest towards meeting Net Zero targets.…”
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Development of a novel Cas13a/Cas12a-mediated 'one-pot' dual detection assay for genetically modified crops by Lin Ding, Xiaofu Wang, Xiaoyun Chen, Xiaoli Xu, Wei Wei, Lei Yang, Yi Ji, Jian Wu, Junfeng Xu, Cheng Peng

“…This innovative approach combined Multiplex RPA (recombinase polymerase amplification) with the Dual CRISPR (clustered regularly interspaced short palindromic repeat) assay technique, to provide a streamlined and efficient method for GM crop detection. …”
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Adeno‐Associated Virus 8 and 9 Myofibre Type/Size Tropism Profiling Reveals Therapeutic Effect of Microdystrophin in Canines by Matthew J. Burke, Braiden M. Blatt, James A. Teixeira, Dennis O. Pérez‐López, Yongping Yue, Xiufang Pan, Chady H. Hakim, Gang Yao, Roland W. Herzog, Dongsheng Duan

“…Conclusions Our studies suggest that AAV8 and AAV9 transduce fast and slow myofibres at equivalent efficiency. Importantly, uDys therapy effectively prevented dystrophic myofibre atrophy. …”
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Global drought tolerant maize research and development: Analysis and visualization of cutting-edge scientific technologies by Muhammad Azrai, Abdul Haris Bahrun, Roy Efendi, Nining Nurini Andayani, Muhammad Jihad, Bahtiar, Bunyamin Zainuddin, Muslimin, Muhammad Aqil

“…Integrating cutting-edge breeding tools such as HTPP and genome editing/CRISPR-Cas9 indicates a shift toward improving breeding efficiency and accuracy. Future research aims to refine precision editing techniques and promote transparent communication for ethical deployment. …”
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Reducing enteric methane emission in dairy goats: impact of dietary inclusions of quebracho tannin extract on ruminal microbiota by Paola Cremonesi, Marco Severgnini, Marco Severgnini, Marco Battelli, Valentina Monistero, Martina Penati, Alessia Libera Gazzonis, Alessia Libera Gazzonis, Bianca Castiglioni, Luca Rapetti, Maria Teresa Manfredi, Maria Teresa Manfredi, Maria Filippa Addis, Maria Filippa Addis

“…IntroductionCondensed tannins (CT) influence ruminal microbiota, feed digestibility, and methane emissions, yet their effects in goats are poorly understood.MethodsThis study evaluated the impact of dietary quebracho CT extract at 0%, 2%, 4%, or 6% of dry matter on the composition of the dairy goat ruminal microbiota with a two-times repeated 4 × 4 Latin square design. Bacterial, archaeal, fungal, and protozoan communities were analyzed at the end of each feeding period for relative abundance changes, and their relationship to methane production, nutrient digestibility and feed efficiency were also assessed.ResultsIncreasing CT levels reduced alpha- and beta-diversity, with the 6% CT diet showing the most pronounced decline. …”
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Unravelling the advances of CRISPR-Cas9 as a precise antimicrobial therapy: A systematic review by Hannay Crystynah Almeida de Souza, Pedro Panzenhagen, Anamaria Mota Pereira dos Santos, Ana Beatriz Portes, Juliana Fidelis, Carlos Adam Conte-Junior

“…This review highlights new perspectives for the clinical use of CRISPR-Cas9 as a specific and efficient antimicrobial agent, potentially replacing traditional broad-spectrum antimicrobials in the future.…”
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Durable HTT silencing using non-evolved dCas9 epigenome editors in patient-derived cells by Jennifer J. Waldo, Julian A.N.M. Halmai, Ankita Singh, Casiana E. Gonzalez, Yi-An Chen, Shaylyn A. Carthen, Jan A. Nolta, Kyle D. Fink

“…Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by a trinucleotide repeat expansion in exon 1 of the huntingtin (HTT) gene. …”
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Isotropic, high-resolution, whole-chest inversion recovery contrast-enhanced magnetic resonance angiography in under 4.5 min using image-based navigator fluoro trigger by Jason Craft, Roosha Parikh, Josh Y. Cheng, Nancy Diaz, Karl P. Kunze, Michaela Schmidt, Radhouene Neji, Amanda Leung, Suzanne Weber, Jonathan Weber, Timothy Carter, Sylvia Biso, Ann-Marie Yamashita, Eric H. Wolff, Claudia Prieto, Claudia Prieto, Rene M. Botnar, Rene M. Botnar, Rene M. Botnar

“…Electrocardiogram (ECG) gated, contrast-enhanced (CE), inversion recovery gradient echo MRA is efficient and historically provides low artifact burden, but the window for imaging with weak albumin binding extracellular gadolinium based contrast agents is small. …”
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Clinical–radiomics model for predicting internal mammary lymph node metastasis in operable breast cancer patients by Wei Wang, Wenyu Zhang, Ting Yu, Ting Yu, QingWei Wu, ChengLin Yang, ChengLin Yang, Jianbin Li

“…DCA substantiated the clinical–radiomics model’s optimal predictive efficiency, enhanced discriminatory ability, and maximum benefit. …”
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Genome editing in grain legumes for food security by Joshua Yeboah Asiamah, Sakina Haruna Mahdi, Kusum R. Tamang, Christian Bryan Carson, Prabesh Koirala, Emily Anne Reed, Aaron Tettey Asare, Anu Augustine, Milind B. Ratnaparkhe, Kailash C. Bansal, Babu Valliyodan

“…The advent of this technology has transformed genetic modification by offering exceptional precision and efficiency. This progress has enabled the creation of grain legumes that are more resistant to climate change and enhanced with improved nutritional content. …”
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Development of Rifampicin Eye Drops for the Treatment of Exudative Age-Related Macular Degeneration by Valory Anne S. Vailoces, Andrew J. Tolentino, Jose Fernando Arevalo, Ron A. Adelman, Robert Bhisitkul, Diana V. Do, Quan Dong Nguyen, Michael J. Tolentino, Masaki Tanito, Hiroaki Serizawa

“…<b>Conclusions</b>: Rifampicin was delivered to the sub-retina in rabbits with an efficiency greater than the effective dose required for inhibiting neovascularization. …”
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Identification and Genetic Diversity Analysis of <i>Cucurbita</i> Varieties Based on SSR Markers by Jialong Zou, Xingting Wu, Xuejing Liu, Changcheng Peng, Yingxue Ma, Xiujie Zhang, Xuhong Yang, Shuailong Luo, Weigeng Xing, Hao Hong, Lang Li, Bin Tan, Ruonan Jing, Zhenjiang Xu

“…Our research results provide a new tool for population genetic analysis, variety identification, and protection in <i>Cucurbita</i> cultivars with high efficiency, accuracy, and lower costs compared to conventional methods.…”
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Role of GuaB, the inosine-5′-monophosphate dehydrogenase of uropathogenic Escherichia coli pathogenicity: a key factor for bladder infection by Mizuki Shimokawa, Ayako Takita, Kazutomo Suzue, Ayuko Kimura, Himari Tabo, Yumika Sato, Yuya Yanagita, Takuya Sadahira, Haruyoshi Tomita, Hidetada Hirakawa

“…The GuaB mutant showed impaired growth in urine-mimicking conditions and reduced infection efficiency, attributed to decreased GMP production. …”
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Problems of Regional Identification of Production Losses from the COVID-19 Pandemic and their Solutions in the System of International Statistical Standards by A. B. Dukhon, O. I. Obraztsova, N. D. Epshtein

“…The approved list of such types of activities over the past 2 months has been repeatedly adjusted by the Government of the Russian Federation, taking into account the recommendations of experts and proposals of business-structures, in order to ensure the highest efficiency and targeted state support for manufacturers. …”
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Long-Term Results of Laser Submucosal Destruction in the Treatment of Grade 2–3 Hemorrhoids by M. G. Yusova, V. Yu. Korolik, A. M. Kuzminov, D. V. Vyshegorodtsev, Yu. L. Trubacheva, T. A. Alibekova

“…Laser submucosal destruction of internal hemorrhoids using a laser with a wavelength of 1940 nm is a minimally invasive method for treating Grade 2–3 of hemorrhoidal disease, which has demonstrated high efficiency (good results) in the late postoperative period. …”
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A Model of Human Resource Management System Suitable for the New Generation Z in Executive Organizations with Thematic Analysis Approach by Moein Pourahmadi, Saeed Jafarinia, Yusuf Vakili, Akbar Hasanpour

“…Objective The continuity of a society is ensured by the process of socialization that transfers the social traditions of previous generations to new generations; that is, new generations never exactly repeat the social life of their predecessors step by step, but are always accompanied by criticism of some aspects of tradition or innovation. …”
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Modelling the potential financial impacts of expanding access to immune checkpoint inhibitors as monotherapy for treating advanced non-small cell lung cancerResearch in context by Kiu Tay-Teo, Dario Trapani, Manju Sengar, Zeba Aziz, Filip Meheus, André Ilbawi, Elisabeth G.E. de Vries, Lorenzo Moja

“…Policymakers should negotiate lower prices to ensure cost-effectiveness and affordability, improve spending efficiency by optimised dosing and treatment duration, and enhance health system capacity, including ensuring appropriate use and introducing biosimilars. …”
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Review of Demand Response-based Optimal Scheduling of Electric and Thermal Integrated Energy Systems by Jingshan MO, Guangxian YAN, Na SONG, Mingyang YUAN

“…Comparative analysis indicates that, compared to the unified solution, the hierarchical solution maintains the independence of each subsystem and achieves a globally optimal solution. However, the repeated iterations required during solving reduce solving efficiency. …”
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