Optimization Design of Fast Neutron Target Station Beam Extraction Based on Genetic Algorithm by QIN Ziqian1, 2, 3, TAN Xinjian2, 3, ZHANG Xiaodong2, 3, PAN Qingquan1, LIU Xiao2, 3

“…During calibration, the intensity of neutrons will also affect the overall efficiency, so the value of the uncollided neutron flux is also an important design indicator. …”
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Effect of sanitation on soil-transmitted helminth infection: systematic review and meta-analysis. by Kathrin Ziegelbauer, Benjamin Speich, Daniel Mäusezahl, Robert Bos, Jennifer Keiser, Jürg Utzinger

“…However, rapid reinfection of humans occurs after successful deworming, and therefore effective preventive measures are required to achieve public health goals with optimal efficiency and sustainability.<h4>Methods and findings</h4>We conducted a systematic review and meta-analysis to assess the effect of sanitation (i.e., access and use of facilities for the safe disposal of human urine and feces) on infection with soil-transmitted helminths. …”
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Optimization and calibration of 384-well kinetic Ca2+ mobilization assays for the human transient receptor potential cation channels TRPM8, TRPV1, and TRPA1 by David A. Close, V. Blair Journigan, Paul A. Johnston

“…Heterologous expression of hTRPM8 in HEK293T cells was required for anti-TRPM8 antibody staining and TRPM8 agonist induced Ca2+ mobilization signals which were both used to optimize transfection efficiency. FLIPR Calcium 6 dye concentration, loading time, and TRPM8 transfected cell seeding density were optimized and a DMSO tolerance of ≤0.2 % was set. …”
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Clinical and microbial study of reinforced 3D-printed maxillary denture base resin: a randomized trial by Eman Mohamed Ahmed Teama, Hoda Mohamed Amin Rashad, Eman Abd El-salam Mohamed Shakal, Eman Elsayed Hegazy

“…The values of microbial colonization and patient satisfaction were analyzed via repeated-measures ANOVA followed by Tukey’s multiple comparison test. …”
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Applications of mutagenesis methods on affinity maturation of antibodies in vitro by LIU Yuan, LIN Manman, ZHANG Xiao, XU Chongxin, JIAO Linxia, ZHONG Jianfeng, WU Aihua, LIU Xianjin

“…But there are also some reports on producing the affinity-matured antibodies by heavy chain shuffling.These mutagenesis methods have been used with various degrees of success. However, the efficiency of these methods was relatively low and there was a lack of a rational guidance to choose these methods. …”
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Study of Knowledge, Attitude, and Practices of Use of Masks among Health-care Workers at a Tertiary Care Center in Mumbai by Sharan Sadashiva Kadamba, Kalpana Tikaram Suryavanshi, Khushi P. Bhatia

“…Results: The analysis of survey data provides insightful perspectives on respondents’ comprehension and attitudes toward airborne infection transmission and the usage of N-95 masks. 68.6% of respondents recognized that all listed diseases (measles, TB, and chickenpox) were spread by the airborne route. 55.6% of respondents correctly acknowledged that all masks, including surgical masks, N-95 masks, and cotton masks, do not offer airborne protection. 76.0% of respondents acknowledged that N-95 masks possess a high filtration efficiency against 0.3-micron particles, 58.3% correctly identified that “N” in N-95 stands for “not resistant to oil,” and 90.8% acknowledged that the N-95 respirator as the most common type of respirators. 41.7% correctly acknowledged that N-95 masks with an exhalation valve are not recommended for use. 22.2% of respondents incorrectly believe that wearing a face mask can lead to carbon dioxide poisoning, and 52.1% of respondents correctly identified that pulmonary TB patients need not be provided with N-95 masks in isolation rooms. 76.8% of respondents understood that fit testing is required every time one dons an N-95 mask. 95.5% of respondents recognized the necessity of hand hygiene before donning and after doffing N-95 masks. 82.7% of respondents agreed regarding the necessity for consultation before N-95 mask usage for chronic lung disease and asthma patients. 93.7% are aware that there is a protocol for donning and doffing N-95 masks. 71.3% of respondents understood that extended use involves wearing the same N-95 respirator for repeated close contact encounters without removing the mask between patient encounters, while 64.4% correctly define reuse as using the same N-95 respirator for multiple encounters but removing it after each encounter.…”
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WideConvNet: A Novel Wide Convolutional Neural Network Applied to ERP-Based Classification of Alcoholics by Abdul Baseer Buriro, Attaullah Buriro, Aziz Altaf Khuwaja, Abdul Aziz Memon, Nabeel Siddiqui, Stephen J. Weddell, Richard D. Jones

“…The findings suggest that WideConvNet, specifically on short-duration EEG signals, offers a balanced solution, combining robust classification performance with improved computational efficiency, making it suitable for clinical diagnosis and real-time brain-computer interface (BCI) applications.…”
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The effectiveness of myofascial massage of the gastrocnemius muscle on the threshold and pain tolerance by Karolina PAWLIKOWSKA, Aleksandra JAŻDŻEWSKA, Jakub KORTAS

“…Background: The aim of the study was to assess the effectiveness of the myofascial self-massage technique of the gastrocnemius muscle in determining the possibility of increasing pain tolerance and individual pain threshold, which could increase exercise efficiency, allow for greater training loads and accelerate post-exercise regeneration, as well as to determine the subjective assessment of pain intensity using the VAS scale. …”
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A soybean lysolecithin emulsion has small particle size and thermal, acid, and salt tolerance by Yasuhiko Tsuji, Makoto Matsushita, Yuki Fujimoto, Akihito Hayashi, Natsuko Miki, Rie Ito, Yusuke Iwasaki, Kazuhiro Kagotani, Hiroshi Akiyama

“…Thus, enzymatically hydrolyzed lecithin, specifically SLP-lyso, offers significantly higher production efficiency and emulsion stability than non-enzymatically hydrolyzed lecithin.…”
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RAD-Seq-derived SSR markers: a new paradigm for genetic analysis and construction of genetically improved production populations in Pinus koraiensis by Pingyu Yan, Wanying Zhang, Junfei Hao, Xiaotian Miao, Jun Wu, Zixiong Xie, Zhixin Li, Lei Zhang, Hanguo Zhang

“…Abstract Background The principal objective of this research is to develop highly specific polymorphic molecular markers, with the aim of addressing the paucity of simple sequence repeat (SSR) markers in Pinus koraiensis. The objective of this initiative is to facilitate the efficient management of genetic resources within Pinus koraiensis, enable precise pedigree identification and establish a foundational framework for subsequent whole-genome sequencing and assembly strategies. …”
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Integrated agro-morphological and molecular characterization for progeny testing to enhance alfalfa breeding in arid regions of Tunisia by Samir Tlahig, Amina Mohamed, Tebra Triki, Yassine Yahia, Jamila Yehmed, Hedi Yahia, Ferdaous Guasmi, Mohamed Loumerem

“…The integration of molecular and phenotypic data proved to be an efficient strategy for progeny testing and elite genotype selection. …”
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Design and Characterization of Bispecific and Trispecific Antibodies Targeting SARS-CoV-2 by Jiayang Wang, Qi Qian, Yushan Jiang, Zuxin Liang, Yun Peng, Wei Zhao, Yang Yang, Chenguang Shen

“…The pseudoviruses’ neutralization assay and the virus challenge to BALB/c mice were deployed to assess the efficiency of recombinant antibodies in vitro and in vivo. …”
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Subjective cognitive decline predicts longitudinal neuropsychological test performance in an unsupervised online setting in the Brain Health Registry by Jae Myeong Kang, Manchumad Manjavong, Chengshi Jin, Adam Diaz, Miriam T. Ashford, Joseph Eichenbaum, Emily Thorp, Elizabeth Wragg, Kenton H. Zavitz, Francesca Cormack, Anna Aaronson, R. Scott Mackin, Rachana Tank, Bernard Landavazo, Erika Cavallone, Diana Truran, Sarah Tomaszewski Farias, Michael W. Weiner, Rachel L. Nosheny

“…Abstract Backgrounds Digital, online assessments are efficient means to detect early cognitive decline, but few studies have investigated the relationship between remotely collected subjective cognitive change and cognitive decline. …”
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Electrochemical modulation of tau protein phosphorylation levels with biomimetic polyaniline membranes by Shang-Chi Chien, Chia-Hsuan Chang, Hung-Ju Wang, Chien-Chih Hsu, Yu-Lin Wang, Ching-Cheng Chuang, Jung-Chih Chen

“…Electrochemical quartz crystal microbalance (EQCM) measurements showcased a maximum adsorption efficiency of 40 %, with desorption efficiencies reaching 16.67 % at negative potentials. …”
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Isolation and characterization of Acinetobacter phage vAbaIN10 active against carbapenem-resistant Acinetobacter baumannii (CRAB) isolates from healthcare-associated infections in... by Issa Ndiaye, Laurent Debarbieux, Ousmane Sow, Bissoume Sambe Ba, Moussa Moise Diagne, Abdoulaye Cissé, Cheikh Fall, Yakhya Dieye, Ndongo Dia, Guillaume Constantin de Magny, Abdoulaye Seck

“…Isolation, host range, efficiency of plating, temperature and pH stability, lysis kinetics, one-step growth test, sequencing, and genomic analysis were performed. …”
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The Effect of Mattress Firmness on Sleep Architecture and PSG Characteristics by Hu X, Gao Y, Song Y, Yang X, Liu K, Luo B, Sun Y, Li L

“…Sleep architecture and neurophysiological activity were assessed using polysomnography (PSG), with EEG-derived features, including power spectral characteristics, sleep spindle activity, and slow-wave parameters, further analyzed.Results: Our findings indicate that a medium-firm mattress provides better sleep quality, reflected in a narrower range (Range=xmax-xmin) of sleep duration, efficiency, and sleep latency, as well as increased sleep spindle activity. …”
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Recent advances in aptamer-based biosensing technology for isolation and detection of extracellular vesicles by Osama Alnaser-Almusa, Mohammed Mahmoud, Mohammed Ilyas, Raghda Adwan, Farah Abul Rub, Noha Alnaser-Almusa, Fayrouz Mustafa, Sana Ahmed, Alaa Alzhrani, Alaa Alzhrani, Alaa Alzhrani, Tanveer Ahmad Mir, Tanveer Ahmad Mir, Mubarak. Alabudahash, Raja Chinnappan, Raja Chinnappan, Ahmed Yaqinuddin

“…However, these techniques often suffer from limitations in sensitivity, specificity, and efficiency, hindering their performance and reliability in research and clinical settings. …”
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Analysis of microsatellite and single nucleotide polymorphism within transcriptomic database in Cymbidium ensi folium by Li Xiaobai, Xiang Lin, Luo Jie, Qin Dehui, Sun Chongbo

“…The program Msatcommander was used to analyze microsatellite (as called simple sequence repeat, SSR) frequencies. The minimum numbers of repeats for SSR detection were as follows: six repeats for di- SSRs; and four for tri-, tetra-, penta- and hexa-SSRs. …”
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Acute effects of isolated and combined dietary nitrate and caffeine ingestion on ergometer-based 1000 m time trial performance in highly trained kayakers by Johannes Pollex, Martin Behrens, Thomas Mittlmeier, Sven Bruhn, Matthias Weippert

“…These findings might be related to the dosage and/or a ceiling effect due to the already efficient vascular, metabolic, and muscle function, including high amounts of endogenous produced nitric oxide, in athletes.…”
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Pragmatic questionnaire-based evaluation of auditory function in individuals with major neurocognitive disorders and hearing loss in diverse contexts by Panagiotis Alexopoulos, Panagiotis Alexopoulos, Panagiotis Alexopoulos, Panagiotis Alexopoulos, Antonios Alexandros Demertzis, Panagiotis Biris, Polychronis Economou, Eric Frison, Piers Dawes, Iracema Leroi

“…The HHIE-8 model was less effective (MSE = 7.740), and the model including HHIE and no demographic data was the least reliable (MSE = 9.220).ConclusionHHIE-S and HHIE-2 combined with demographic data are practical and more efficient tools for assessing hearing loss severity in people with dementia and hearing impairment compared to HHIE, HHIE-S and HHIE-SP in different European countries. …”
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