Radiomic features and tumor immune microenvironment associated with anaplastic lymphoma kinase-rearranged lung adenocarcinoma and their prognostic value by Ying Han, Wenya Feng, Wenya Feng, Huaxin Li, Hua Wang, Hua Wang, Zhaoxiang Ye

“…The number of CD8+ T cells and Human leukocyte antigen class I (HLA-I)/programmed death ligand 1 (PD-L1) expression were determined using immunohistochemistry. …”
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Identification and analysis of cuproptosis associated molecular clusters and immunological profiles in atopic dermatitis by Liangzhe Wang, Bo Wang, Min Peng, Xiaoyan Yang, Sijia Huang, Ruixin Wang, Lin Du, Ruiqian Yao, Wei Wang, Baiping Dong, Yuanjie Zhu, Yuanjie Zhu

“…The role of cuproptosis, a novel form of programmed cell death, in AD is not yet understood.MethodsThe GSE107361 dataset was obtained from the Gene Expression Omnibus (GEO) database. …”
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Combining Unity with machine vision to create low latency, flexible and simple virtual realities by Yuri Ogawa, Raymond Aoukar, Richard Leibbrandt, Jake S. Manger, Zahra M. Bagheri, Luke Turnbull, Chris Johnston, Pavan K. Kaushik, Jaxon Mitchell, Jan M. Hemmi, Karin Nordström

“…In both cases, real‐time tracking was interfaced with Unity to control the location and rotation of the tethered animal's avatar in the virtual world. We developed a user‐friendly Unity Editor interface, CAVE, to simplify experimental design and data storage without the need for coding. …”
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The prevalence of metabolic syndrome in patients with non-alcoholic fatty liver disease in primary care clinics at King Saud University Medical City, Riyadh, Saudi Arabia by Alanoud Maan Alyousef, Alanoud Maan Alyousef, Doaa Zeinhom Mekawy, Doaa Zeinhom Mekawy, Yaser Yousef Bashumeel, Saleh Magdy Mohamed, Turky H. Almigbal, Turky H. Almigbal, Mohammed A. Batais, Mohammed A. Batais, Abdullah A. Alrasheed, Abdullah A. Alrasheed

“…Metabolic syndrome was defined according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP/ATP III) criteria, which require at least three of five metabolic risk factors to be present. …”
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Pre-treatment peripheral blood TCR repertoire as a predictor of response in patients with NSCLC treated with immunochemotherapy by Yong Yang, Hui-yu Jiang, Yuan Li, Fang Wu, Zhao-yang Chen, Guo-ping Zheng, Wen-Zhong Su, Hai-long Wang, Min Pang

“…Methods Blood samples were collected from patients with advanced NSCLC before initiating anti-programmed cell death 1 (anti-PD-1) antibody treatment in combination with chemotherapy. …”
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Liver metastases in thyroid cancer: epidemiology, risk stratification and survival outcomes in the immunotherapy era by Ming-Lu Xu, Yang-Yang Wang, Li-Ping Xie, Ning Ding, Jia-Jun Hui

“…The predictive nomogram was developed for liver metastasis risk assessment, validated using concordance index, calibration curves, receiver operating characteristic (ROC) curves, and decision curve analysis (DCA). …”
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Determining an Optimal Combination of Meteorological Factors to Reduce the Intensity of Atmospheric Pollution During Prescribed Straw Burning by Luyan He, Lingjian Duanmu, Li Guo, Yang Qin, Bowen Shi, Lin Liang, Weiwei Chen

“…This study conducted a three-year monitoring program in Changchun, a core agricultural area in Northeast China severely affected by straw burning. …”
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Secondary malignancies in non‐Hodgkin lymphoma survivors: 40 years of follow‐up assessed by treatment modality by Matthew W. Parsons, Calvin Rock, Jonathan J. Chipman, Harsh R. Shah, Boyu Hu, Deborah M. Stephens, Randa Tao, Jonathan D. Tward, David K. Gaffney

“…Results In total, 15,979 patients developed SM, more than the endemic rate (O/E 1.29; p < 0.05). …”
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How to improve support for people with (complex) multiple-problems through social prescribing in a vulnerable neighborhood; professionals’, experts-by-experience’ and clients’ pers... by C. Bos, S. Vader, N. van Vooren, K. Jerković-Ćosić, B. Keij

“…Similar findings have been observed in the Netherlands, where a SP program has been developed in 2018. This study examines the perspectives of health and care professionals, experts-by-experience, and clients regarding the design and implementation of social prescribing in vulnerable neighborhoods in order to better support people with (complex) multiple-problems. …”
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Multicenter validation of an RNA-based assay to predict anti-PD-1 disease control in patients with recurrent or metastatic head and neck squamous cell carcinoma: the PREDAPT study by Howard L McLeod, A Dimitrios Colevas, Georges Azzi, Kevin C Flanagan, Douglas Adkins, Jessica Ley, Ezra E W Cohen, James Wade, Jon Earls, Jeffrey Hiken, Rachel L Wellinghoff, Michelle M Ponder, William H Westra, Vera Vavinskaya, Leisa Sutton, Ida Deichaite, Orlan K Macdonald, Karim Welaya, Andrew W Pippas, Jennifer Slim, Bruce Bank, Xingwei Sui, Steven E Kossman, Todd D Shenkenberg, Warren L Alexander, Katharine A Price, David N Messina, Jarret I Glasscock, Eric J Duncavage

“…Background Despite advances in cancer care and detection, &gt;65% of patients with squamous cell cancer of the head and neck (HNSCC) will develop recurrent and/or metastatic disease. The prognosis for these patients is poor with a 5-year overall survival of 39%. …”
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Quantitative insights into stroke recovery utilizing delayed vessel ratio from color-coded multiphase computed tomography angiography by Yu Lin, Yu Lin, Yu Lin, Xiaoxiao Zhang, Zhen Xing, Xiefeng Yang, Qingwen Tong, Shaomao Lv, Jinan Wang, Jinan Wang, Dairong Cao, Dairong Cao, Dairong Cao, Dairong Cao

“…Collateral ratio and delayed vessel ratio (DVR) were determined through semi-automatic delineation and calculation on the anterior cerebral artery regions and Alberta Stroke Program Early CT (ASPECT) Score regions of cmCTA maps. …”
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Digital therapeutics approach for young children with myopia using SAT-001 (DAYS): study protocol for a randomized controlled trial by Hae Jung Paik, Byung Joo Lee, Dong Hui Lim, So Young Han, Eun Hye Jung, Hyun Jin Shin, Hyun Kyung Kim, Ungsoo Samuel Kim, Won Jae Kim, Hee Young Choi, Jihae Park, Soolienah Rhiu, Jihye Lee, Moonjeong Kim, Kyunghee Kim

“…SAT-001 is a novel digital therapeutic software developed for myopia control and is designed to overcome the limitations of existing therapies. …”
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Breast cancer risk and prevention in 2024: An overview from the Breast Cancer UK ‐ Breast Cancer Prevention Conference by Britta Stordal, Michelle Harvie, Michael N. Antoniou, Michelle Bellingham, Doris S. M. Chan, Philippa Darbre, Oskar Karlsson, Andreas Kortenkamp, Pamela Magee, Stefano Mandriota, Elisabete Silva, James E. Turner, Laura N. Vandenberg, D. Gareth Evans

“…Increasing body‐mass index is associated with increased risk of developing postmenopausal breast cancer, but with decreased risk of premenopausal breast cancer. …”
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Machine Learning Accurately Predicts Need for Critical Care Support in Patients Admitted to Hospital for Community-Acquired Pneumonia by George S. Chen, BSc, Terry Lee, PhD, Jennifer L.Y. Tsang, MD, Alexandra Binnie, MD, Anne McCarthy, MD, Juthaporn Cowan, MD, Patrick Archambault, MD, Francois Lellouche, MD, Alexis F. Turgeon, MD, MSc, Jennifer Yoon, MD, Francois Lamontagne, MD, Allison McGeer, MD, Josh Douglas, MD, Peter Daley, MD, Robert Fowler, MD, David M. Maslove, MD, Brent W. Winston, MD, Todd C. Lee, MD, Karen C. Tran, MD, Matthew P. Cheng, MD, Donald C. Vinh, MD, John H. Boyd, MD, Keith R. Walley, MD, Joel Singer, PhD, John C. Marshall, MD, James A. Russell, MD, for the Community-Acquired Pneumonia: Toward InnoVAtive Treatment (CAPTIVATE) Investigators

“…Hospitalized community-acquired pneumonia (CAP) patients are admitted for ventilation, vasopressors, and renal replacement therapy (RRT). This study aimed to develop a machine learning (ML) model that predicts the need for such interventions and compare its accuracy to that of logistic regression (LR). …”
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Comparative Benefits of Primary Percutaneous Coronary Intervention Versus Onsite Fibrinolytic for Patients With ST‐Segment–Elevation Myocardial Infarction: A Quasi‐Experimental Stu... by Shuduo Zhou, Siwei Xie, Binquan You, Dingcheng Xiang, Weiyi Fang, Michael G. Trisolini, Kenneth A. Labresh, Sidney C. Smith, Zhi‐Jie Zheng, Yinzi Jin, Feng Liu, Yong Huo

“…However, the contemporaneous data to inform the comparative benefits of primary PCI versus O‐FT, especially in developing countries, have been largely understudied. …”
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Low Genetic Diversity Study on Leopard Coral Grouper Plectropomus leopardus (Perciformes: Serranidae) from Sulawesi, Indonesia by Andi Aliah Hidayani, Asmi Citra Malina A. R. Tasakka, Widyastuti Umar, Md. Jobaidul Alam, Amit Kumer Neogi, Sapto Andriyono

“…DNA information has been beneficial in efforts to the breeding program and develop grouper aquaculture activities. …”
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Autoantibody-positivity before and seroconversion during treatment with anti-PD-1 is associated with immune-related adverse events in patients with melanoma by Diane van der Woude, Theo Rispens, Catharina M Korse, Sjoerd H van der Burg, Ellen Kapiteijn, John B A G Haanen, Winan J van Houdt, Els M E Verdegaal, Marij J P Welters, Jessica S W Borgers, Tineke J van Wesemael, Johannes V van Thienen, Kyra A Gelderman, Dirk J A R Moes

“…Introduction Treatment with the immune checkpoint inhibitor anti-programmed cell death protein-1 (PD-1) often causes immune-related adverse events (irAEs). …”
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Differential expansion of circulating human MDSC subsets in patients with cancer, infection and inflammation by Ang Lin, Sven Brandau, Stephan Lang, Luca Cassetta, Kirsten Bruderek, Joanna Skrzeczynska-Moncznik, Oktawia Osiecka, Xiaoying Hu, Ida Marie Rundgren, Kim Santegoets, Utku Horzum, Ana Godinho-Santos, Gennadiy Zelinskyy, Thalia Garcia-Tellez, Sunčica Bjelica, Bartłomiej Taciak, Astrid Olsnes Kittang, Benedikt Höing, Michael Dixon, Verena Müller, Jochen Sven Utikal, Derya Karakoç, Kerim Bora Yilmaz, Emilia Górka, Lubomir Bodnar, Olympia Evdoxia Anastasiou, Christine Bourgeois, Robert Badura, Monika Kapinska-Mrowiecka, Mirjana Gotic, Mark ter Laan, Esther Kers-Rebel, Magdalena Król, Juan Francisco Santibañez, Michaela Müller-Trutwin, Ulf Dittmer, Ana Espada de Sousa, Güneş Esendağlı, Gosse Adema, Karin Loré, Elisabeth Ersvær, Viktor Umansky, Jeffrey W Pollard, Joanna Cichy

“…PMN-MDSC expansion was more pronounced in cancer compared with infection and inflammation. Programmed death-ligand 1 was primarily expressed in M-MDSC and e-MDSC and was not upregulated as a consequence of disease. …”
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A mixed methods study protocol for CONFIVAC, an intervention to enhance paediatric nurses' and paediatricians' skills to promote vaccination and vaccine confidence by Elisabet Henderson, Sara Valmayor, Victoria Porthé, Alba Asensio, Xavier Bruna, Usue Elizondo-Alzola, Anna Ramirez-Morros, Gemma Ricós, Josep Vidal-Alaball, M. Isabel Pasarín, Cristina Rius, Elena Roel, Elia Díez

“…PHCWs in the intervention arm will participate in the training program CONFIVAC, which includes 10 h of online learning and 2 h of in-person training featuring role-playing exercises. …”
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Successful Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) deployment by emergency medicine physicians for refractory non-traumatic cardiac arrest by Graham Brant-Zawadzki, Guillaume L. Hoareau, H. Hill Stoecklein, Nicholas Levin, Craig H. Selzman, Anna Ciullo, Joseph Tonna, Christopher Kelly, Jamal Jones, Scott T. Youngquist, M. Austin Johnson

“…Methods: We describe an emergency medicine-driven training program and treatment protocol developed to deploy REBOA in the emergency department for patients experiencing refractory out-of-hospital cardiac arrest and deemed ineligible for ECPR. …”
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